Activated platelets present high mobility group box 1 to neutrophils, inducing autophagy and promoting the extrusion of neutrophil extracellular traps

Instructive influences of phagocytic clearance of dying cells on neutrophil extracellular trap generation

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Leukocyte HMGB1 Is Required for Vessel Remodeling in Regenerating Muscles

(2014) L. Campana et al.   JOURNAL OF IMMUNOLOGY

Neutrophil extracellular traps form predominantly during the organizing stage of human venous thromboembolism development

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Oxidative Stress Elicits Platelet/Leukocyte Inflammatory Interactions via HMGB1: A Candidate for Microvessel Injury in Sytemic Sclerosis

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Elevated Levels of Circulating DNA and Chromatin Are Independently Associated With Severe Coronary Atherosclerosis and a Prothrombotic State

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Neutrophils Recruited to Sites of Infection Protect from Virus Challenge by Releasing Neutrophil Extracellular Traps

(2013) Craig N. Jenne et al.   Cell Host & Microbe

Cellular signalling of the receptor for advanced glycation end products (RAGE)

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Circulating platelets as a source of the damage-associated molecular pattern HMGB1 in patients with systemic sclerosis

(2012) Norma Maugeri et al.   AUTOIMMUNITY

Extracellular DNA traps are associated with the pathogenesis of TRALI in humans and mice

(2012) G. M. Thomas et al.   BLOOD

Neutrophil extracellular traps (NETs) and infection-related vascular dysfunction

(2012) Elizabeth E. Gardiner et al.   BLOOD REVIEWS

p53/HMGB1 Complexes Regulate Autophagy and Apoptosis

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Neutrophil extracellular traps: Is immunity the second function of chromatin?

(2012) Volker Brinkmann et al.   JOURNAL OF CELL BIOLOGY

Platelets induce neutrophil extracellular traps in transfusion-related acute lung injury

(2012) Axelle Caudrillier et al.   JOURNAL OF CLINICAL INVESTIGATION

Mutually exclusive redox forms of HMGB1 promote cell recruitment or proinflammatory cytokine release

(2012) Emilie Venereau et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo

(2012) Marie-Luise von Brühl et al.   JOURNAL OF EXPERIMENTAL MEDICINE

An Intense and Short-Lasting Burst of Neutrophil Activation Differentiates Early Acute Myocardial Infarction from Systemic Inflammatory Syndromes

(2012) Norma Maugeri et al.   PLoS One

Autophagy Mediates the Delivery of Thrombogenic Tissue Factor to Neutrophil Extracellular Traps in Human Sepsis

(2012) Konstantinos Kambas et al.   PLoS One

Platelet-leukocyte deregulated interactions foster sterile inflammation and tissue damage in immune-mediated vessel diseases

(2012) Norma Maugeri et al.   THROMBOSIS RESEARCH

HMGB1 Is a Therapeutic Target for Sterile Inflammation and Infection

(2011) Ulf Andersson et al.   Annual Review of Immunology

Metabolic regulation by HMGB1-mediated autophagy and mitophagy

(2011) Rui Kang et al.   Autophagy

Clearance of circulating activated platelets in polycythemia vera and essential thrombocythemia

(2011) N. Maugeri et al.   BLOOD

Extracellular histones promote thrombin generation through platelet-dependent mechanisms: involvement of platelet TLR2 and TLR4

(2011) F. Semeraro et al.   BLOOD

Dying for a cause: NETosis, mechanisms behind an antimicrobial cell death modality

(2011) Q Remijsen et al.   CELL DEATH AND DIFFERENTIATION

High-Mobility Group Box 1 Is Essential for Mitochondrial Quality Control

(2011) Daolin Tang et al.   Cell Metabolism

Repeat measurements of glycated haemoglobin A1c and N-terminal pro-B-type natriuretic peptide: divergent behaviour in diabetes mellitus

(2011) Stephanie Neuhold et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Early and Transient Release of Leukocyte Pentraxin 3 during Acute Myocardial Infarction

(2011) N. Maugeri et al.   JOURNAL OF IMMUNOLOGY

Extracellular histones increase plasma thrombin generation by impairing thrombomodulin-dependent protein C activation

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Neutrophil extracellular traps promote deep vein thrombosis in mice

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The neutrophil in vascular inflammation

(2011) Mia Phillipson et al.   NATURE MEDICINE

Neutrophil Extracellular Trap Formation Is Associated with IL-1β and Autophagy-Related Signaling in Gout

(2011) Ioannis Mitroulis et al.   PLoS One

Platelet–Leukocyte Interactions in Cardiovascular Disease and Beyond

(2010) Licia Totani et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Neutrophil extracellular trap cell death requires both autophagy and superoxide generation

(2010) Quinten Remijsen et al.   CELL RESEARCH

Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibition

(2010) Alessandro Luciani et al.   NATURE CELL BIOLOGY

Reciprocal coupling of coagulation and innate immunity via neutrophil serine proteases

(2010) Steffen Massberg et al.   NATURE MEDICINE

Extracellular DNA traps promote thrombosis

(2010) T. A. Fuchs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proteomic identification of interactions between histones and plasma proteins: Implications for cytoprotection

(2010) Alan D. Pemberton et al.   PROTEOMICS

Leukocyte and platelet activation in patients with giant cell arteritis and polymyalgia rheumatica: A clue to thromboembolic risks?

(2009) Norma Maugeri et al.   AUTOIMMUNITY

Neutrophils phagocytose activated platelets in vivo: a phosphatidylserine, P-selectin, and  2 integrin-dependent cell clearance program

(2009) N. Maugeri et al.   BLOOD

Platelets: Guardians of Tumor Vasculature

(2009) B. Ho-Tin-Noe et al.   CANCER RESEARCH

Dangerous connections: neutrophils and the phagocytic clearance of activated platelets

(2009) Angelo A Manfredi et al.   CURRENT OPINION IN HEMATOLOGY

The alarmin HMGB1 acts in synergy with endogenous and exogenous danger signals to promote inflammation

(2009) Hulda Sigridur Hreggvidsdottir et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Platelet functions beyond hemostasis

(2009) S. S. SMYTH et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Heterotypic interactions enabled by polarized neutrophil microdomains mediate thromboinflammatory injury

(2009) Andrés Hidalgo et al.   NATURE MEDICINE

Netting neutrophils in autoimmune small-vessel vasculitis

(2009) Kai Kessenbrock et al.   NATURE MEDICINE

Significant Association Between Neutrophil Aggregation in Aspirated Thrombus and Myocardial Damage in Patients With ST-Segment Elevation Acute Myocardial Infarction

(2008) Kentaro Arakawa et al.   CIRCULATION JOURNAL