NETosis promotes chronic inflammation and fibrosis in systemic lupus erythematosus and COVID-19

Targeting chronic COVID-19 lung injury; Tofacitinib can be used against tissue-resident memory T cells

(2022) Sepideh Zununi Vahed et al.   BIOMEDICINE & PHARMACOTHERAPY

CX3CR1 might be a promising predictor of systemic lupus erythematosus patients with pulmonary fibrosis

(2021) Fen Qiu et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

IFN-γ and TNF-α drive a CXCL10+ CCL2+ macrophage phenotype expanded in severe COVID-19 lungs and inflammatory diseases with tissue inflammation

(2021) Fan Zhang et al.   Genome Medicine

Erythroid mitochondrial retention triggers myeloid-dependent type I interferon in human SLE

(2021) Simone Caielli et al.   CELL

Interplay between Extracellular Matrix and Neutrophils in Diseases

(2021) Yanyan Zhu et al.   Journal of Immunology Research

Neutrophil Extracellular Traps Induce the Epithelial-Mesenchymal Transition: Implications in Post-COVID-19 Fibrosis

(2021) Laura Pandolfi et al.   Frontiers in Immunology

First lung transplant in Wuhan for a critical and elderly COVID‐19 patient

(2021) Bo Wang et al.   Immunity Inflammation and Disease

Zinc-dependent histone deacetylases drive neutrophil extracellular trap formation and potentiate local and systemic inflammation

(2021) Valentina Poli et al.   iScience

Initial CT findings and temporal changes in patients with the novel coronavirus pneumonia (2019-nCoV): a study of 63 patients in Wuhan, China

(2020) Yueying Pan et al.   EUROPEAN RADIOLOGY

Pulmonary pathology of early phase 2019 novel coronavirus (COVID-19) pneumonia in two patients with lung cancer

(2020) Sufang Tian et al.   Journal of Thoracic Oncology

Abnormal pulmonary function in COVID-19 patients at time of hospital discharge

(2020) Xiaoneng Mo et al.   EUROPEAN RESPIRATORY JOURNAL

Post‐mortem examination of COVID19 patients reveals diffuse alveolar damage with severe capillary congestion and variegated findings of lungs and other organs suggesting vascular dysfunction

(2020) T. Menter et al.   HISTOPATHOLOGY

Postmortem Examination of Patients With COVID-19

(2020) Tina Schaller et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Retrospective analysis of laboratory testing in 54 patients with severe- or critical-type 2019 novel coronavirus pneumonia

(2020) Yanlei Li et al.   LABORATORY INVESTIGATION

Epidemiology, clinical course, and outcomes of critically ill adults with COVID-19 in New York City: a prospective cohort study

(2020) Matthew J Cummings et al.   LANCET

Pulmonary fibrosis secondary to COVID-19: a call to arms?

(2020) Paolo Spagnolo et al.   Lancet Respiratory Medicine

Pulmonary fibrosis and COVID-19: the potential role for antifibrotic therapy

(2020) Peter M George et al.   Lancet Respiratory Medicine

Chronic Hypersensitivity Pneumonitis, an Interstitial Lung Disease with Distinct Molecular Signatures

(2020) Haruhiko Furusawa et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Combined anti-fibrotic and anti-inflammatory properties of JAK-inhibitors on macrophages in vitro and in vivo: Perspectives for scleroderma-associated interstitial lung disease

(2020) Alain Lescoat et al.   BIOCHEMICAL PHARMACOLOGY

Neutrophil Extracellular Traps (NETs) Contribute to Immunothrombosis in COVID-19 Acute Respiratory Distress Syndrome

(2020) Elizabeth A Middleton et al.   BLOOD

Pathophysiology, Transmission, Diagnosis, and Treatment of Coronavirus Disease 2019 (COVID-19)

(2020) W. Joost Wiersinga et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Attenuation of Dupuytren’s fibrosis via targeting of the STAT1 modulated IL-13Rα1 response

(2020) Moeed Akbar et al.   Science Advances

Cannabidiol Modifies the Formation of NETs in Neutrophils of Psoriatic Patients

(2020) Piotr Wójcik et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Neutrophil extracellular traps infiltrate the lung airway, interstitial, and vascular compartments in severe COVID-19

(2020) Coraline Radermecker et al.   JOURNAL OF EXPERIMENTAL MEDICINE

SARS-CoV-2–triggered neutrophil extracellular traps mediate COVID-19 pathology

(2020) Flavio Protasio Veras et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Postmortem Findings in Italian Patients With COVID-19: A Descriptive Full Autopsy Study of Cases With and Without Comorbidities

(2020) Laura Falasca et al.   JOURNAL OF INFECTIOUS DISEASES

Respiratory follow-up of patients with COVID-19 pneumonia

(2020) Peter M George et al.   THORAX

Fibrosis: from mechanisms to medicines

(2020) Neil C. Henderson et al.   NATURE

Protein Arginine Deiminases (PADs): Biochemistry and Chemical Biology of Protein Citrullination

(2019) Santanu Mondal et al.   ACCOUNTS OF CHEMICAL RESEARCH

An emerging role of neutrophils and NETosis in chronic inflammation and fibrosis in systemic lupus erythematosus (SLE) and ANCA-associated vasculitides (AAV): Implications for the pathogenesis and treatment

(2019) Eleni Frangou et al.   AUTOIMMUNITY REVIEWS

Functional disparities within the TIMP family in cancer: hints from molecular divergence

(2019) Celina Eckfeld et al.   CANCER AND METASTASIS REVIEWS

Impaired efferocytosis and neutrophil extracellular traps clearance by macrophages in ARDS

(2018) Murielle Grégoire et al.   EUROPEAN RESPIRATORY JOURNAL

The NET-effect of combining rituximab with belimumab in severe systemic lupus erythematosus

(2018) Tineke Kraaij et al.   JOURNAL OF AUTOIMMUNITY

REDD1/autophagy pathway promotes thromboinflammation and fibrosis in human systemic lupus erythematosus (SLE) through NETs decorated with tissue factor (TF) and interleukin-17A (IL-17A)

(2018) Eleni Frangou et al.   ANNALS OF THE RHEUMATIC DISEASES

Regulated in development and DNA damage responses 1 (REDD1) links stress with IL-1β–mediated familial Mediterranean fever attack through autophagy-driven neutrophil extracellular traps

(2017) Panagiotis Skendros et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Complex heatmaps reveal patterns and correlations in multidimensional genomic data

(2016) Zuguang Gu et al.   BIOINFORMATICS

Peptidylarginine deiminase 4 promotes age-related organ fibrosis

(2016) Kimberly Martinod et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Neutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease

(2016) Christian Lood et al.   NATURE MEDICINE

Tofacitinib Ameliorates Murine Lupus and Its Associated Vascular Dysfunction

(2016) Yasuko Furumoto et al.   Arthritis & Rheumatology

Matrix Metalloproteinases as Therapeutic Targets for Idiopathic Pulmonary Fibrosis

(2015) Vanessa J. Craig et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Meta- and Orthogonal Integration of Influenza “OMICs” Data Defines a Role for UBR4 in Virus Budding

(2015) Shashank Tripathi et al.   Cell Host & Microbe

Treg depletion attenuates irradiation-induced pulmonary fibrosis by reducing fibrocyte accumulation, inducing Th17 response, and shifting IFN-γ, IL-12/IL-4, IL-5 balance

(2015) Shanshan Xiong et al.   IMMUNOBIOLOGY

Robust enumeration of cell subsets from tissue expression profiles

(2015) Aaron M Newman et al.   NATURE METHODS

Exhaled IL-8 in Systemic Lupus Erythematosus with and without Pulmonary Fibrosis

(2014) Agnieszka Nielepkowicz-Goździńska et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Diverse functions of matrix metalloproteinases during fibrosis

(2014) M. Giannandrea et al.   Disease Models & Mechanisms

Neutrophil extracellular traps promote differentiation and function of fibroblasts

(2014) Akrivi Chrysanthopoulou et al.   JOURNAL OF PATHOLOGY

Pulmonary Manifestations of Systemic Lupus Erythematosus

(2014) Charlene Fell et al.   SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

Profibrotic Activities for Matrix Metalloproteinase-8 during Bleomycin-Mediated Lung Injury

(2013) V. J. Craig et al.   JOURNAL OF IMMUNOLOGY

An Improved Strategy to Recover Large Fragments of Functional Human Neutrophil Extracellular Traps

(2013) Lorena Barrientos et al.   Frontiers in Immunology

NET balancing: a problem in inflammatory lung diseases

(2013) Olivia Z. Cheng et al.   Frontiers in Immunology

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Neutrophil Extracellular Traps Directly Induce Epithelial and Endothelial Cell Death: A Predominant Role of Histones

(2012) Mona Saffarzadeh et al.   PLoS One

Matrix Metalloproteinase 3 Is a Mediator of Pulmonary Fibrosis

(2011) Cory M. Yamashita et al.   AMERICAN JOURNAL OF PATHOLOGY

Dying for a cause: NETosis, mechanisms behind an antimicrobial cell death modality

(2011) Q Remijsen et al.   CELL DEATH AND DIFFERENTIATION

Systemic Lupus Erythematosus

(2011) George C. Tsokos   NEW ENGLAND JOURNAL OF MEDICINE

Impairment of neutrophil extracellular trap degradation is associated with lupus nephritis

(2010) A. Hakkim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA