Serum extracellular traps associate with the activation of myeloid cells in SLE patients with the low level of anti-DNA antibodies

TLR7 gain-of-function genetic variation causes human lupus

(2022) Grant J. Brown et al.   NATURE

Potentiation of NETs release is novel characteristic of TREM-1 activation and the pharmacological inhibition of TREM-1 could prevent from the deleterious consequences of NETs release in sepsis

(2021) Amir Boufenzer et al.   Cellular & Molecular Immunology

Bite of the wolf: innate immune responses propagate autoimmunity in lupus

(2021) Sarthak Gupta et al.   JOURNAL OF CLINICAL INVESTIGATION

C-Reactive Protein Levels in Systemic Lupus Erythematosus Are Modulated by the Interferon Gene Signature and CRP Gene Polymorphism rs1205

(2021) Helena Enocsson et al.   Frontiers in Immunology

Dynamic landscape of immune cell-specific gene regulation in immune-mediated diseases

(2021) Mineto Ota et al.   CELL

ELISA detection of MPO-DNA complexes in human plasma is error-prone and yields limited information on neutrophil extracellular traps formed in vivo

(2021) Hubert Hayden et al.   PLoS One

Phase 1 double-blind randomized safety trial of the Janus kinase inhibitor tofacitinib in systemic lupus erythematosus

(2021) Sarfaraz A. Hasni et al.   Nature Communications

Monocyte-driven atypical cytokine storm and aberrant neutrophil activation as key mediators of COVID-19 disease severity

(2021) L. Vanderbeke et al.   Nature Communications

Comment on: Neutrophil extracellular traps in giant cell arteritis biopsies: presentation, localization and co-expression with inflammatory cytokines

(2021) Norio Hanata et al.   RHEUMATOLOGY

Neutrophil Extracellular Traps Contribute to COVID-19 Hyperinflammation and Humoral Autoimmunity

(2021) Jiram Torres-Ruiz et al.   Cells

Peptidylarginine Deiminase 4 Promotes the Renal Infiltration of Neutrophils and Exacerbates the TLR7 Agonist-Induced Lupus Mice

(2020) Norio Hanata et al.   Frontiers in Immunology

Neutrophil extracellular traps in COVID-19

(2020) Yu Zuo et al.   JCI Insight

Modulation of cardiometabolic disease markers by type I interferon inhibition in systemic lupus erythematosus

(2020) Kerry A Casey et al.   Arthritis & Rheumatology

2019 update of the EULAR recommendations for the management of systemic lupus erythematosus

(2019) Antonis Fanouriakis et al.   ANNALS OF THE RHEUMATIC DISEASES

Neutrophil Extracellular Traps (NETs) profiles in patients with incident SLE and lupus nephritis

(2019) Maurizio Bruschi et al.   JOURNAL OF RHEUMATOLOGY

Combined genetic and transcriptome analysis of patients with SLE: distinct, targetable signatures for susceptibility and severity

(2019) Nikolaos I Panousis et al.   ANNALS OF THE RHEUMATIC DISEASES

A Neutrophil Activation Biomarker Panel in Prognosis and Monitoring of Patients with Rheumatoid Arthritis

(2019) Mary Bach et al.   Arthritis & Rheumatology

Pathogenic and Therapeutic Relevance of JAK/STAT Signaling in Systemic Lupus Erythematosus: Integration of Distinct Inflammatory Pathways and the Prospect of Their Inhibition with an Oral Agent

(2019) Alessia Alunno et al.   Cells

Transcriptomic, epigenetic, and functional analyses implicate neutrophil diversity in the pathogenesis of systemic lupus erythematosus

(2019) Pragnesh Mistry et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neutrophil extracellular traps identify patients at risk of increased disease activity and cardiovascular comorbidity in systemic lupus erythematosus

(2019) Stanley Moore et al.   JOURNAL OF RHEUMATOLOGY

Differential ubiquitination in NETs regulates macrophage responses in systemic lupus erythematosus

(2018) Ana Barrera-Vargas et al.   ANNALS OF THE RHEUMATIC DISEASES

The ratio of erythrocyte sedimentation rate to C-reactive protein is useful in distinguishing infection from flare in systemic lupus erythematosus patients presenting with fever

(2018) E Littlejohn et al.   LUPUS

Peripheral Immunophenotyping Identifies Three Subgroups Based on T Cell Heterogeneity in Lupus Patients

(2017) Satoshi Kubo et al.   Arthritis & Rheumatology

Transcriptional firing helps to drive NETosis

(2017) Meraj A. Khan et al.   Scientific Reports

Neutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease

(2016) Christian Lood et al.   NATURE MEDICINE

Neutrophil Extracellular Trap Formation Is Independent of De Novo Gene Expression

(2016) Gabriel Sollberger et al.   PLoS One

Enhanced Formation and Disordered Regulation of NETs in Myeloperoxidase-ANCA-Associated Microscopic Polyangiitis

(2014) D. Nakazawa et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Plasma IL-6 levels correlate with clinical and ultrasound measures of arthritis in patients with systemic lupus erythematosus

(2013) EMA Ball et al.   LUPUS

Low-density granulocytes: a distinct class of neutrophils in systemic autoimmunity

(2013) Carmelo Carmona-Rivera et al.   Seminars in Immunopathology

Derivation and validation of the Systemic Lupus International Collaborating Clinics classification criteria for systemic lupus erythematosus

(2012) Michelle Petri et al.   ARTHRITIS AND RHEUMATISM

Systemic Lupus Erythematosus

(2011) George C. Tsokos   NEW ENGLAND JOURNAL OF MEDICINE

Neutrophils Activate Plasmacytoid Dendritic Cells by Releasing Self-DNA-Peptide Complexes in Systemic Lupus Erythematosus

(2011) R. Lande et al.   Science Translational Medicine

Netting Neutrophils Are Major Inducers of Type I IFN Production in Pediatric Systemic Lupus Erythematosus

(2011) G. S. Garcia-Romo et al.   Science Translational Medicine

C4BPB/C4BPA is a new susceptibility locus for venous thrombosis with unknown protein S-independent mechanism: results from genome-wide association and gene expression analyses followed by case-control studies

(2010) A. Buil et al.   BLOOD

Impairment of neutrophil extracellular trap degradation is associated with lupus nephritis

(2010) A. Hakkim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Extracellular DNA traps promote thrombosis

(2010) T. A. Fuchs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Netting neutrophils in autoimmune small-vessel vasculitis

(2009) Kai Kessenbrock et al.   NATURE MEDICINE