Decreased miR-4512 Levels in Monocytes and Macrophages of Individuals With Systemic Lupus Erythematosus Contribute to Innate Immune Activation and Neutrsophil NETosis by Targeting TLR4 and CXCL2

Cultured human uveal melanocytes express/secrete CXCL1 and CXCL2 constitutively and increased by lipopolysaccharide via activation of Toll-like receptor 4

(2021) Dan-Ning Hu et al.   CURRENT EYE RESEARCH

Efficacy and safety of NI-0101, an anti-toll-like receptor 4 monoclonal antibody, in patients with rheumatoid arthritis after inadequate response to methotrexate: a phase II study

(2020) Emmanuel Monnet et al.   ANNALS OF THE RHEUMATIC DISEASES

Neutrophil extracellular traps amplify neutrophil recruitment and inflammation in neutrophilic asthma by stimulating the airway epithelial cells to activate the TLR4/ NF-κB pathway and secrete chemokines

(2020) Rongjun Wan et al.   Aging-US

MicroRNA-30e-5p has an Integrated Role in the Regulation of the Innate Immune Response during Virus Infection and Systemic Lupus Erythematosus

(2020) Richa Mishra et al.   iScience

Innate Immune Cells' Contribution to Systemic Lupus Erythematosus

(2019) Andrés A. Herrada et al.   Frontiers in Immunology

ANA as an entry criterion for the classification of SLE

(2019) David S. Pisetsky et al.   AUTOIMMUNITY REVIEWS

Innate immunity as the trigger of systemic autoimmune diseases

(2019) Victoria Saferding et al.   JOURNAL OF AUTOIMMUNITY

miR-125b is downregulated in systemic lupus erythematosus patients and inhibits autophagy by targeting UVRAG

(2018) Wenting Cao et al.   BIOMEDICINE & PHARMACOTHERAPY

The role of neutrophil extracellular traps in rheumatic diseases

(2018) Falko Apel et al.   Nature Reviews Rheumatology

Enhanced expression of TREM-1 in splenic cDCs in lupus prone mice and it was modulated by miRNA-150

(2017) Sheng Gao et al.   MOLECULAR IMMUNOLOGY

Diminished neutrophil extracellular trap (NET) formation is a novel innate immune deficiency induced by acute ethanol exposure in polymicrobial sepsis, which can be rescued by CXCL1

(2017) Liliang Jin et al.   PLoS Pathogens

Profiling analysis of circulating microRNA in peripheral blood of patients with class IV lupus nephritis

(2017) Elkin Navarro-Quiroz et al.   PLoS One

The role of microRNAs in the pathogenesis of autoimmune diseases

(2016) Ji-Qing Chen et al.   AUTOIMMUNITY REVIEWS

Dual blockade of the pro-inflammatory chemokine CCL2 and the homeostatic chemokine CXCL12 is as effective as high dose cyclophosphamide in murine proliferative lupus nephritis

(2016) Satish Kumar Devarapu et al.   CLINICAL IMMUNOLOGY

CCL21 and IP-10 as blood biomarkers for pulmonary involvement in systemic lupus erythematosus patients

(2016) B Odler et al.   LUPUS

The role of neutrophils and NETosis in autoimmune and renal diseases

(2016) Sarthak Gupta et al.   Nature Reviews Nephrology

CXCL13 blockade attenuates lupus nephritis of MRL/lpr mice

(2015) Xiaobei Wu et al.   ACTA HISTOCHEMICA

MiR-125a targets effector programs to stabilize Treg-mediated immune homeostasis

(2015) Wen Pan et al.   Nature Communications

Type I Interferon Inhibition of MicroRNA-146a Maturation Through Up-Regulation of Monocyte Chemotactic Protein-Induced Protein 1 in Systemic Lupus Erythematosus

(2015) Bo Qu et al.   Arthritis & Rheumatology

A Comparative Review of Toll-Like Receptor 4 Expression and Functionality in Different Animal Species

(2014) Céline Vaure et al.   Frontiers in Immunology

Chemokine (C–X–C motif) ligand (CXCL)10 in autoimmune diseases

(2013) Alessandro Antonelli et al.   AUTOIMMUNITY REVIEWS

Mast cell and macrophage chemokines CXCL1/CXCL2 control the early stage of neutrophil recruitment during tissue inflammation

(2013) K. De Filippo et al.   BLOOD

Anticancer Properties of the IL-12 Family - Focus on Colorectal Cancer

(2012) M. A. Engel et al.   CURRENT MEDICINAL CHEMISTRY

Dysregulated expression of CXCR4/CXCL12 in subsets of patients with systemic lupus erythematosus

(2010) Andrew Wang et al.   ARTHRITIS AND RHEUMATISM

Inducible microRNA-155 Feedback Promotes Type I IFN Signaling in Antiviral Innate Immunity by Targeting Suppressor of Cytokine Signaling 1

(2010) P. Wang et al.   JOURNAL OF IMMUNOLOGY

CXCR2 mediates NADPH oxidase–independent neutrophil extracellular trap formation in cystic fibrosis airway inflammation

(2010) Veronica Marcos et al.   NATURE MEDICINE

Critical Role of TLR2 and TLR4 in Autoantibody Production and Glomerulonephritis in lpr Mutation-Induced Mouse Lupus

(2009) A. Lartigue et al.   JOURNAL OF IMMUNOLOGY

Immunopathogenesis of HCV-related endocrine manifestations in chronic hepatitis and mixed cryoglobulinemia

(2008) Alessandro Antonelli et al.   AUTOIMMUNITY REVIEWS