Defense systems to avoid ferroptosis caused by lipid peroxidation-mediated membrane damage

Dietary restriction of cysteine and methionine sensitizes gliomas to ferroptosis and induces alterations in energetic metabolism

(2023) Pavan S. Upadhyayula et al.   Nature Communications

p53 in ferroptosis regulation: the new weapon for the old guardian

(2022) Yanqing Liu et al.   CELL DEATH AND DIFFERENTIATION

COX-2/PGE2 Pathway Inhibits the Ferroptosis Induced by Cerebral Ischemia Reperfusion

(2022) Yunfei Xu et al.   MOLECULAR NEUROBIOLOGY

PKCβII phosphorylates ACSL4 to amplify lipid peroxidation to induce ferroptosis

(2022) Hai-Liang Zhang et al.   NATURE CELL BIOLOGY

5-Lipoxygenase Inhibition Protects Retinal Pigment Epithelium from Sodium Iodate-Induced Ferroptosis and Prevents Retinal Degeneration

(2022) Jong-Jer Lee et al.   Oxidative Medicine and Cellular Longevity

Nutritional and Metabolic Control of Ferroptosis

(2022) Eikan Mishima et al.   Annual Review of Nutrition

Redox Activation of Mitochondrial DAMPs and the Metabolic Consequences for Development of Autoimmunity

(2022) Andreas Koenig et al.   ANTIOXIDANTS & REDOX SIGNALING

CD8+ T cells and fatty acids orchestrate tumor ferroptosis and immunity via ACSL4

(2022) Peng Liao et al.   CANCER CELL

Hydrogen sulfide alleviates particulate matter-induced emphysema and airway inflammation by suppressing ferroptosis

(2022) Ying Wang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Activation of MAT2A-ACSL3 pathway protects cells from ferroptosis in gastric cancer

(2022) Mingzhe Ma et al.   FREE RADICAL BIOLOGY AND MEDICINE

Involvement of FSP1-CoQ10-NADH and GSH-GPx-4 pathways in retinal pigment epithelium ferroptosis

(2022) Ming Yang et al.   Cell Death & Disease

Which cell death modality wins the contest for photodynamic therapy of cancer?

(2022) Tatiana Mishchenko et al.   Cell Death & Disease

A targetable CoQ-FSP1 axis drives ferroptosis- and radiation-resistance in KEAP1 inactive lung cancers

(2022) Pranavi Koppula et al.   Nature Communications

Methionine Deprivation Reveals the Pivotal Roles of Cell Cycle Progression in Ferroptosis That Is Induced by Cysteine Starvation

(2022) Takujiro Homma et al.   Cells

PLA2G6 Silencing Suppresses Melanoma Progression and Affects Ferroptosis Revealed by Quantitative Proteomics

(2022) Yifei Wang et al.   Frontiers in Oncology

The Role of Photodynamic Therapy in Triggering Cell Death and Facilitating Antitumor Immunology

(2022) Liuchang Tan et al.   Frontiers in Oncology

Edaravone Modulates Neuronal GPX4/ACSL4/5-LOX to Promote Recovery After Spinal Cord Injury

(2022) Yilin Pang et al.   Frontiers in Cell and Developmental Biology

Superoxide Radicals in the Execution of Cell Death

(2022) Junichi Fujii et al.   Antioxidants

Ferroptosis turns 10: Emerging mechanisms, physiological functions, and therapeutic applications

(2022) Brent R. Stockwell   CELL

Peroxisome proliferator-activated receptor-γ ameliorates neuronal ferroptosis after traumatic brain injury in mice by inhibiting cyclooxygenase-2

(2022) Hui Liang et al.   EXPERIMENTAL NEUROLOGY

Half is enough: Oxidized lysophospholipids as novel bioactive molecules

(2022) Toni Petan et al.   FREE RADICAL BIOLOGY AND MEDICINE

A non-canonical vitamin K cycle is a potent ferroptosis suppressor

(2022) Eikan Mishima et al.   NATURE

Hydrogen Sulfide Inhibits Ferroptosis in Cardiomyocytes to Protect Cardiac Function in Aging Rats

(2022) Zihui Liang et al.   Frontiers in Molecular Biosciences

Ascorbate Is a Primary Antioxidant in Mammals

(2022) Junichi Fujii et al.   MOLECULES

Hydropersulfides inhibit lipid peroxidation and ferroptosis by scavenging radicals

(2022) Uladzimir Barayeu et al.   Nature Chemical Biology

Acute lymphoblastic leukemia necessitates GSH-dependent ferroptosis defenses to overcome FSP1-epigenetic silencing

(2022) Lucas B. Pontel et al.   Redox Biology

The lipid flippase SLC47A1 blocks metabolic vulnerability to ferroptosis

(2022) Zhi Lin et al.   Nature Communications

Metformin attenuates hyperlipidaemia-associated vascular calcification through anti-ferroptotic effects

(2021) Wen-Qi Ma et al.   FREE RADICAL BIOLOGY AND MEDICINE

Oxidative Stress and Lipid Mediators Modulate Immune Cell Functions in Autoimmune Diseases

(2021) Piotr Wójcik et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Ferroptosis: mechanisms, biology and role in disease

(2021) Xuejun Jiang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Release mechanisms of major DAMPs

(2021) Atsushi Murao et al.   APOPTOSIS

Detection and structural analysis of lipid-derived radicals in vitro and in vivo

(2021) Yuta Matsuoka et al.   FREE RADICAL RESEARCH

Phospholipase iPLA2β averts ferroptosis by eliminating a redox lipid death signal

(2021) Wan-Yang Sun et al.   Nature Chemical Biology

Redox Epiphospholipidome in Programmed Cell Death Signaling: Catalytic Mechanisms and Regulation

(2021) Valerian E. Kagan et al.   Frontiers in Endocrinology

CoenzymeQ in cellular redox regulation and clinical heart failure

(2021) Shuai Yuan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Juggling with lipids, a game of Russian roulette

(2021) Maceler Aldrovandi et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Mitochondrial ferritin attenuates cerebral ischaemia/reperfusion injury by inhibiting ferroptosis

(2021) Peina Wang et al.   Cell Death & Disease

Ferroptotic cell death triggered by conjugated linolenic acids is mediated by ACSL1

(2021) Alexander Beatty et al.   Nature Communications

Signaling pathways and defense mechanisms of ferroptosis

(2021) Jiao Liu et al.   FEBS Journal

Sp1-mediated upregulation of Prdx6 expression prevents podocyte injury in diabetic nephropathy via mitigation of oxidative stress and ferroptosis

(2021) Qianjin Zhang et al.   LIFE SCIENCES

iPLA2β Contributes to ER Stress-Induced Apoptosis during Myocardial Ischemia/Reperfusion Injury

(2021) Tingting Jin et al.   Cells

Mitochondrial Ferritin: Its Role in Physiological and Pathological Conditions

(2021) Sonia Levi et al.   Cells

ACSL family: The regulatory mechanisms and therapeutic implications in cancer

(2021) Jing Quan et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

A novel mechanism linking ferroptosis and endoplasmic reticulum stress via the circPtpn14/miR-351-5p/5-LOX signaling in melatonin-mediated treatment of traumatic brain injury

(2021) Chenrui Wu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Diverse cytoprotective actions of vitamin E isoforms- role as peroxyl radical scavengers and complementary functions with selenoproteins

(2021) Yoshiro Saito   FREE RADICAL BIOLOGY AND MEDICINE

Vitamin E: How much is enough, too much and why!

(2021) Maret G. Traber et al.   FREE RADICAL BIOLOGY AND MEDICINE

Prevention of ferroptosis in acute scenarios: an in vitro study with classic and novel anti-ferroptotic compounds

(2021) Aline Aita Naime et al.   FREE RADICAL RESEARCH

Persister cancer cells: Iron addiction and vulnerability to ferroptosis

(2021) Raphaël Rodriguez et al.   MOLECULAR CELL

Nitric oxide protects against ferroptosis by aborting the lipid peroxidation chain reaction

(2021) Takujiro Homma et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Structural library and visualization of endogenously oxidized phosphatidylcholines using mass spectrometry-based techniques

(2021) Yuta Matsuoka et al.   Nature Communications

Edaravone may prevent ferroptosis in ALS.

(2020) Snežana Spasić et al.   CURRENT DRUG TARGETS

Redox lipid reprogramming commands susceptibility of macrophages and microglia to ferroptotic death

(2020) Alexandr A. Kapralov et al.   Nature Chemical Biology

Cytochrome P450 oxidoreductase contributes to phospholipid peroxidation in ferroptosis

(2020) Yilong Zou et al.   Nature Chemical Biology

Dihydrolipoamide dehydrogenase regulates cystine deprivation-induced ferroptosis in head and neck cancer

(2020) Daiha Shin et al.   Redox Biology

Identification of Frataxin as a regulator of ferroptosis

(2020) Jing Du et al.   Redox Biology

Lipid peroxidation and ferroptosis: The role of GSH and GPx4

(2020) Fulvio Ursini et al.   FREE RADICAL BIOLOGY AND MEDICINE

Structural and Chemical Biology of the Interaction of Cyclooxygenase with Substrates and Non-Steroidal Anti-Inflammatory Drugs

(2020) Carol A. Rouzer et al.   CHEMICAL REVIEWS

Cysteine preservation confers resistance to glutathione-depleted cells against ferroptosis via CDGSH iron sulphur domain-containing proteins (CISDs)

(2020) Takujiro Homma et al.   FREE RADICAL RESEARCH

Non-steroidal anti-inflammatory drugs (NSAIDs) and organ damage: A current perspective

(2020) Samik Bindu et al.   BIOCHEMICAL PHARMACOLOGY

Lymph protects metastasizing melanoma cells from ferroptosis

(2020) Jessalyn M. Ubellacker et al.   NATURE

Plasticity of ether lipids promotes ferroptosis susceptibility and evasion

(2020) Yilong Zou et al.   NATURE

PLA2G6 guards placental trophoblasts against ferroptotic injury

(2020) Ofer Beharier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Membrane Damage during Ferroptosis Is Caused by Oxidation of Phospholipids Catalyzed by the Oxidoreductases POR and CYB5R1

(2020) Bo Yan et al.   MOLECULAR CELL

The Biosynthesis of Enzymatically Oxidized Lipids

(2020) Ali A. Hajeyah et al.   Frontiers in Endocrinology

Characterization of a rat monoclonal antibody raised against ferroptotic cells

(2020) Sho Kobayashi et al.   JOURNAL OF IMMUNOLOGICAL METHODS

ROS and Oxidative Stress Are Elevated in Mitosis during Asynchronous Cell Cycle Progression and Are Exacerbated by Mitotic Arrest

(2019) Jesse C. Patterson et al.   Cell Systems

Chaperone-mediated autophagy is involved in the execution of ferroptosis

(2019) Zheming Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The multiple mechanisms that regulate p53 activity and cell fate

(2019) Antonina Hafner et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Singlet Molecular Oxygen Reactions with Nucleic Acids, Lipids, and Proteins

(2019) Paolo Di Mascio et al.   CHEMICAL REVIEWS

Deubiquitinases Maintain Protein Homeostasis and Survival of Cancer Cells upon Glutathione Depletion

(2019) Isaac S. Harris et al.   Cell Metabolism

Identification of PRDX6 as a regulator of ferroptosis

(2019) Bin Lu et al.   ACTA PHARMACOLOGICA SINICA

The molecular machinery of regulated cell death

(2019) Daolin Tang et al.   CELL RESEARCH

ALOX12 is required for p53-mediated tumour suppression through a distinct ferroptosis pathway

(2019) Bo Chu et al.   NATURE CELL BIOLOGY

Ferroptosis caused by cysteine insufficiency and oxidative insult

(2019) Junichi Fujii et al.   FREE RADICAL RESEARCH

Induction of ferroptosis by singlet oxygen generated from naphthalene endoperoxide

(2019) Takujiro Homma et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Edaravone, a free radical scavenger, protects against ferroptotic cell death in vitro

(2019) Takujiro Homma et al.   EXPERIMENTAL CELL RESEARCH

S1QELs suppress mitochondrial superoxide/hydrogen peroxide production from site IQ without inhibiting reverse electron flow through Complex I

(2019) Hoi-Shan Wong et al.   FREE RADICAL BIOLOGY AND MEDICINE

The relevance of pathophysiological alterations in redox signaling of 4-hydroxynonenal for pharmacological therapies of major stress-associated diseases

(2019) Morana Jaganjac et al.   FREE RADICAL BIOLOGY AND MEDICINE

FSP1 is a glutathione-independent ferroptosis suppressor

(2019) Sebastian Doll et al.   NATURE

The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis

(2019) Kirill Bersuker et al.   NATURE

Regulatory Phenomena in the Glutathione Peroxidase Superfamily

(2019) Regina Brigelius-Flohé et al.   ANTIOXIDANTS & REDOX SIGNALING

Insight into the mechanism of ferroptosis inhibition by ferrostatin-1

(2019) Giovanni Miotto et al.   Redox Biology

GTP Cyclohydrolase 1/Tetrahydrobiopterin Counteract Ferroptosis through Lipid Remodeling

(2019) Vanessa A. N. Kraft et al.   ACS Central Science

Selenium Utilization by GPX4 Is Required to Prevent Hydroperoxide-Induced Ferroptosis

(2018) Irina Ingold et al.   CELL

The tumor suppressor protein p53 and the ferroptosis network

(2018) Rui Kang et al.   FREE RADICAL BIOLOGY AND MEDICINE

How is edaravone effective against acute ischemic stroke and amyotrophic lateral sclerosis?

(2018) Kazutoshi Watanabe et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

12/15 lipoxygenase: A crucial enzyme in diverse types of cell death

(2018) Qiu-Qi Li et al.   NEUROCHEMISTRY INTERNATIONAL

Oxygen radicals, nitric oxide, and peroxynitrite: Redox pathways in molecular medicine

(2018) Rafael Radi   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Unsolved mysteries: How does lipid peroxidation cause ferroptosis?

(2018) Huizhong Feng et al.   PLOS BIOLOGY

Peroxiredoxin 6 phospholipid hydroperoxidase activity in the repair of peroxidized cell membranes

(2018) Aron B. Fisher et al.   Redox Biology

Resolving the Role of Lipoxygenases in the Initiation and Execution of Ferroptosis

(2018) Ron Shah et al.   ACS Central Science

Ferroptosis and necroinflammation, a yet poorly explored link

(2018) Bettina Proneth et al.   CELL DEATH AND DIFFERENTIATION

Emerging cellular functions of the lipid metabolizing enzyme 15-Lipoxygenase-1

(2018) Melis Çolakoğlu et al.   CELL PROLIFERATION

Iron catalysis of lipid peroxidation in ferroptosis: Regulated enzymatic or random free radical reaction?

(2018) D.A. Stoyanovsky et al.   FREE RADICAL BIOLOGY AND MEDICINE

Role of GPX4 in ferroptosis and its pharmacological implication

(2018) Tobias M. Seibt et al.   FREE RADICAL BIOLOGY AND MEDICINE

Role of Mitochondria in Ferroptosis

(2018) Minghui Gao et al.   MOLECULAR CELL

Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways

(2018) David L. Duffy et al.   Nature Communications

DHA inhibits proliferation and induces ferroptosis of leukemia cells through autophagy dependent degradation of ferritin

(2018) Jing Du et al.   FREE RADICAL BIOLOGY AND MEDICINE

The viability of primary hepatocytes is maintained under a low cysteine-glutathione redox state with a marked elevation in ophthalmic acid production

(2017) Jaeyong Lee et al.   EXPERIMENTAL CELL RESEARCH

Iron and thiol redox signaling in cancer: An exquisite balance to escape ferroptosis

(2017) Shinya Toyokuni et al.   FREE RADICAL BIOLOGY AND MEDICINE

Lipid peroxidation in face of DNA damage, DNA repair and other cellular processes

(2017) Barbara Tudek et al.   FREE RADICAL BIOLOGY AND MEDICINE

Genotoxicity of lipid oxidation compounds

(2017) Peter M. Eckl et al.   FREE RADICAL BIOLOGY AND MEDICINE

Pathophysiology of mitochondrial lipid oxidation: Role of 4-hydroxynonenal (4-HNE) and other bioactive lipids in mitochondria

(2017) Mengqing Xiao et al.   FREE RADICAL BIOLOGY AND MEDICINE

Chemistry and analysis of HNE and other prominent carbonyl-containing lipid oxidation compounds

(2017) Bebiana C. Sousa et al.   FREE RADICAL BIOLOGY AND MEDICINE

NFS1 undergoes positive selection in lung tumours and protects cells from ferroptosis

(2017) Samantha W. Alvarez et al.   NATURE

Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway

(2017) Vasanthi S. Viswanathan et al.   NATURE

Mitochondrial complex I inhibition triggers a mitophagy-dependent ROS increase leading to necroptosis and ferroptosis in melanoma cells

(2017) Farhan Basit et al.   Cell Death & Disease

BID links ferroptosis to mitochondrial cell death pathways

(2017) Sandra Neitemeier et al.   Redox Biology

On the Mechanism of Cytoprotection by Ferrostatin-1 and Liproxstatin-1 and the Role of Lipid Peroxidation in Ferroptotic Cell Death

(2017) Omkar Zilka et al.   ACS Central Science

“Only a Life Lived for Others Is Worth Living”: Redox Signaling by Oxygenated Phospholipids in Cell Fate Decisions

(2017) Yulia Y. Tyurina et al.   ANTIOXIDANTS & REDOX SIGNALING

Autophagy promotes ferroptosis by degradation of ferritin

(2016) Wen Hou et al.   Autophagy

iPLA2β deficiency attenuates obesity and hepatic steatosis in ob / ob mice through hepatic fatty-acyl phospholipid remodeling

(2016) Xiuling Deng et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Suppressors of Superoxide-H 2 O 2 Production at Site I Q of Mitochondrial Complex I Protect against Stem Cell Hyperplasia and Ischemia-Reperfusion Injury

(2016) Martin D. Brand et al.   Cell Metabolism

Peroxiredoxin 6 homodimerization and heterodimerization with glutathione S-transferase pi are required for its peroxidase but not phospholipase A2 activity

(2016) Suiping Zhou et al.   FREE RADICAL BIOLOGY AND MEDICINE

Fluorescence probes to detect lipid-derived radicals

(2016) Ken-ichi Yamada et al.   Nature Chemical Biology

Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis

(2016) Valerian E Kagan et al.   Nature Chemical Biology

ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition

(2016) Sebastian Doll et al.   Nature Chemical Biology

Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis

(2016) Wan Seok Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ferroptosis: Death by Lipid Peroxidation

(2016) Wan Seok Yang et al.   TRENDS IN CELL BIOLOGY

The Protective Role of Mitochondrial Ferritin on Erastin-Induced Ferroptosis

(2016) Yue-Qi Wang et al.   Frontiers in Aging Neuroscience

Glutathione peroxidase 4 and vitamin E cooperatively prevent hepatocellular degeneration

(2016) Bradley A. Carlson et al.   Redox Biology

Systematic Analysis of Gene Expression Alterations and Clinical Outcomes for Long-Chain Acyl-Coenzyme A Synthetase Family in Cancer

(2016) Wei-Ching Chen et al.   PLoS One

Expression of Inactive Glutathione Peroxidase 4 Leads to Embryonic Lethality, and Inactivation of the Alox15 Gene Does Not Rescue Such Knock-In Mice

(2015) Simone Hanna Brütsch et al.   ANTIOXIDANTS & REDOX SIGNALING

Peroxiredoxin 6 triggers melanoma cell growth by increasing arachidonic acid-dependent lipid signalling

(2015) A. Schmitt et al.   BIOCHEMICAL JOURNAL

Loss ofPLA2G6leads to elevated mitochondrial lipid peroxidation and mitochondrial dysfunction

(2015) Kerri J. Kinghorn et al.   BRAIN

Calcium-independent phospholipases A2and their roles in biological processes and diseases

(2015) Sasanka Ramanadham et al.   JOURNAL OF LIPID RESEARCH

Glutaminolysis and Transferrin Regulate Ferroptosis

(2015) Minghui Gao et al.   MOLECULAR CELL

Ferroptosis as a p53-mediated activity during tumour suppression

(2015) Le Jiang et al.   NATURE

Regulation of Ferroptotic Cancer Cell Death by GPX4

(2014) Wan Seok Yang et al.   CELL

The 2-Oxoacid Dehydrogenase Complexes in Mitochondria Can Produce Superoxide/Hydrogen Peroxide at Much Higher Rates Than Complex I

(2014) Casey L. Quinlan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ferrostatins Inhibit Oxidative Lipid Damage and Cell Death in Diverse Disease Models

(2014) Rachid Skouta et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

(2014) Jose Pedro Friedmann Angeli et al.   NATURE CELL BIOLOGY

Reactive cysteine persulfides and S-polythiolation regulate oxidative stress and redox signaling

(2014) T. Ida et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Redox status in mammalian cells and stem cells during culture in vitro: Critical roles of Nrf2 and cystine transporter activity in the maintenance of redox balance

(2014) Tetsuro Ishii et al.   Redox Biology

Catalytic Characterization of Human Microsomal Glutathione S-Transferase 2: Identification of Rate-Limiting Steps

(2013) Shabbir Ahmad et al.   BIOCHEMISTRY

Chemistry of phospholipid oxidation

(2012) Ana Reis et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

Polymorphisms in Nevus-Associated Genes MTAP, PLA2G6, and IRF4 and the Risk of Invasive Cutaneous Melanoma

(2012) Marina Kvaskoff et al.   Twin Research and Human Genetics

The oxidative stress-inducible cystine/glutamate antiporter, system x c − : cystine supplier and beyond

(2011) Marcus Conrad et al.   AMINO ACIDS

Programmed Cell Death in Animal Development and Disease

(2011) Yaron Fuchs et al.   CELL

Kinetic and Structural Investigations of the Allosteric Site in Human Epithelial 15-Lipoxygenase-2

(2009) Aaron T. Wecksler et al.   BIOCHEMISTRY

Lipid peroxidation: Physiological levels and dual biological effects

(2009) Etsuo Niki   FREE RADICAL BIOLOGY AND MEDICINE

Protein S-glutathionylation: a regulatory device from bacteria to humans

(2009) Isabella Dalle-Donne et al.   TRENDS IN BIOCHEMICAL SCIENCES

Age-Related Changes in Bone Morphology Are Accelerated in Group VIA Phospholipase A2 (iPLA2β)-Null Mice

(2008) Sasanka Ramanadham et al.   AMERICAN JOURNAL OF PATHOLOGY

Autoimmunity and oxidatively modified autoantigens

(2008) Biji T. Kurien et al.   AUTOIMMUNITY REVIEWS

Expression of Ca2+-independent and Ca2+-dependent phospholipases A2 and cyclooxygenases in human melanocytes and malignant melanoma cell lines

(2008) Mariagrazia Rita Scuderi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Bid-induced release of AIF from mitochondria causes immediate neuronal cell death

(2008) S Landshamer et al.   CELL DEATH AND DIFFERENTIATION

Glutathione Peroxidase 4 Senses and Translates Oxidative Stress into 12/15-Lipoxygenase Dependent- and AIF-Mediated Cell Death

(2008) Alexander Seiler et al.   Cell Metabolism

The nitrate–nitrite–nitric oxide pathway in physiology and therapeutics

(2008) Jon O. Lundberg et al.   NATURE REVIEWS DRUG DISCOVERY