Methionine Deprivation Reveals the Pivotal Roles of Cell Cycle Progression in Ferroptosis That Is Induced by Cysteine Starvation

Superoxide produced by mitochondrial complex III plays a pivotal role in the execution of ferroptosis induced by cysteine starvation

(2021) Takujiro Homma et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

PDK4 dictates metabolic resistance to ferroptosis by suppressing pyruvate oxidation and fatty acid synthesis

(2021) Xinxin Song et al.   Cell Reports

Energy-stress-mediated AMPK activation inhibits ferroptosis

(2020) Hyemin Lee et al.   NATURE CELL BIOLOGY

HNF4α regulates sulfur amino acid metabolism and confers sensitivity to methionine restriction in liver cancer

(2020) Qing Xu et al.   Nature Communications

The Apparent Requirement for Protein Synthesis during G2 Phase Is due to Checkpoint Activation

(2020) Sarah Lockhead et al.   Cell Reports

The Mechanism of Ferroptosis and Applications in Tumor Treatment

(2020) Xinyue Lin et al.   Frontiers in Pharmacology

ROS and Oxidative Stress Are Elevated in Mitosis during Asynchronous Cell Cycle Progression and Are Exacerbated by Mitotic Arrest

(2019) Jesse C. Patterson et al.   Cell Systems

Ferroptosis caused by cysteine insufficiency and oxidative insult

(2019) Junichi Fujii et al.   FREE RADICAL RESEARCH

Transsulfuration Activity Can Support Cell Growth upon Extracellular Cysteine Limitation

(2019) Jiajun Zhu et al.   Cell Metabolism

Edaravone, a free radical scavenger, protects against ferroptotic cell death in vitro

(2019) Takujiro Homma et al.   EXPERIMENTAL CELL RESEARCH

Role of Mammalian DNA Methyltransferases in Development

(2019) Zhiyuan Chen et al.   Annual Review of Biochemistry

Cell growth potential drives ferroptosis susceptibility in rhabdomyosarcoma and myoblast cell lines

(2018) Silvia Codenotti et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Role of Mitochondria in Ferroptosis

(2018) Minghui Gao et al.   MOLECULAR CELL

The viability of primary hepatocytes is maintained under a low cysteine-glutathione redox state with a marked elevation in ophthalmic acid production

(2017) Jaeyong Lee et al.   EXPERIMENTAL CELL RESEARCH

Loss of cysteinyl-tRNA synthetase (CARS) induces the transsulfuration pathway and inhibits ferroptosis induced by cystine deprivation

(2015) M Hayano et al.   CELL DEATH AND DIFFERENTIATION

Dietary l-methionine restriction decreases oxidative stress in porcine liver mitochondria

(2015) Yang Ying et al.   EXPERIMENTAL GERONTOLOGY

Control of the pericentrosomal H2O2level by peroxiredoxin I is critical for mitotic progression

(2015) Jung Mi Lim et al.   JOURNAL OF CELL BIOLOGY

Glutaminolysis and Transferrin Regulate Ferroptosis

(2015) Minghui Gao et al.   MOLECULAR CELL

Regulation of Ferroptotic Cancer Cell Death by GPX4

(2014) Wan Seok Yang et al.   CELL

Histological detection of catalytic ferrous iron with the selective turn-on fluorescent probe RhoNox-1 in a Fenton reaction-based rat renal carcinogenesis model

(2014) T. Mukaide et al.   FREE RADICAL RESEARCH

Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

(2014) Jose Pedro Friedmann Angeli et al.   NATURE CELL BIOLOGY

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

The influence of reactive oxygen species on cell cycle progression in mammalian cells

(2012) Eline Hendrike Verbon et al.   GENE

The transsulfuration pathway: a source of cysteine for glutathione in astrocytes

(2011) Gethin J. McBean   AMINO ACIDS

The oxidative stress-inducible cystine/glutamate antiporter, system x c − : cystine supplier and beyond

(2011) Marcus Conrad et al.   AMINO ACIDS

Forty percent methionine restriction lowers DNA methylation, complex I ROS generation, and oxidative damage to mtDNA and mitochondrial proteins in rat heart

(2011) Ines Sanchez-Roman et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

A nuclear glutathione cycle within the cell cycle

(2010) Pedro Diaz Vivancos et al.   BIOCHEMICAL JOURNAL

Visualizing Spatiotemporal Dynamics of Multicellular Cell-Cycle Progression

(2008) Asako Sakaue-Sawano et al.   CELL