The 2-Oxoacid Dehydrogenase Complexes in Mitochondria Can Produce Superoxide/Hydrogen Peroxide at Much Higher Rates Than Complex I

Molecular dynamics study of the structural basis of dysfunction and the modulation of reactive oxygen species generation by pathogenic mutants of human dihydrolipoamide dehydrogenase

(2013) Attila Ambrus et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Partitioning of superoxide and hydrogen peroxide production by mitochondrial respiratory complex I

(2013) Vera G. Grivennikova et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

The role of mitochondrial function and cellular bioenergetics in ageing and disease

(2013) M.D. Brand et al.   BRITISH JOURNAL OF DERMATOLOGY

Sites of superoxide and hydrogen peroxide production during fatty acid oxidation in rat skeletal muscle mitochondria

(2013) Irina V. Perevoshchikova et al.   FREE RADICAL BIOLOGY AND MEDICINE

Inhibitors of ROS production by the ubiquinone-binding site of mitochondrial complex I identified by chemical screening

(2013) Adam L. Orr et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondrial glutathione depletion reveals a novel role for the pyruvate dehydrogenase complex as a key H2O2-emitting source under conditions of nutrient overload

(2013) Kelsey H. Fisher-Wellman et al.   FREE RADICAL BIOLOGY AND MEDICINE

Sites of reactive oxygen species generation by mitochondria oxidizing different substrates

(2013) Casey L. Quinlan et al.   Redox Biology

Mitochondrial hydrogen peroxide production as determined by the pyridine nucleotide pool and its redox state

(2012) Alexandra V. Kareyeva et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Native rates of superoxide production from multiple sites in isolated mitochondria measured using endogenous reporters

(2012) Casey L. Quinlan et al.   FREE RADICAL BIOLOGY AND MEDICINE

A Refined Analysis of Superoxide Production by Mitochondrialsn-Glycerol 3-Phosphate Dehydrogenase

(2012) Adam L. Orr et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial Complex II Can Generate Reactive Oxygen Species at High Rates in Both the Forward and Reverse Reactions

(2012) Casey L. Quinlan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Detailed kinetics and regulation of mammalian 2-oxoglutarate dehydrogenase

(2011) Feng Qi et al.   BMC BIOCHEMISTRY

The Mechanism of Superoxide Production by the Antimycin-inhibited Mitochondrial Q-cycle

(2011) Casey L. Quinlan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Superoxide Is Produced by the Reduced Flavin in Mitochondrial Complex I

(2011) Kenneth R. Pryde et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evidence for Two Sites of Superoxide Production by Mitochondrial NADH-Ubiquinone Oxidoreductase (Complex I)

(2011) Jason R. Treberg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The sites and topology of mitochondrial superoxide production

(2010) Martin D. Brand   EXPERIMENTAL GERONTOLOGY

Hydrogen peroxide efflux from muscle mitochondria underestimates matrix superoxide production - a correction using glutathione depletion

(2010) Jason R. Treberg et al.   FEBS Journal

Molecular identification of the enzyme responsible for the mitochondrial NADH-supported ammonium-dependent hydrogen peroxide production

(2010) Alexandra V. Kareyeva et al.   FEBS LETTERS

Metabolic control exerted by the 2-oxoglutarate dehydrogenase reaction: a cross-kingdom comparison of the crossroad between energy production and nitrogen assimilation

(2009) Victoria I. Bunik et al.   BIOCHEMICAL JOURNAL

Reactive oxygen species regulation by AIF- and complex I-depleted brain mitochondria

(2009) Shankar J. Chinta et al.   FREE RADICAL BIOLOGY AND MEDICINE

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

Diphenyleneiodonium acutely inhibits reactive oxygen species production by mitochondrial complex I during reverse, but not forward electron transport

(2008) Adrian J. Lambert et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Dissociation of superoxide production by mitochondrial complex I from NAD(P)H redox state

(2008) Adrian J. Lambert et al.   FEBS LETTERS

α-Ketoglutarate dehydrogenase contributes to production of reactive oxygen species in glutamate-stimulated hippocampal neurons in situ

(2008) G. Zündorf et al.   NEUROSCIENCE

Investigations of the potential effects of phosphorylation of the MWFE and ESSS subunits on complex I activity and assembly

(2007) N. Yadava et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY