Loss ofPLA2G6leads to elevated mitochondrial lipid peroxidation and mitochondrial dysfunction

Lipid peroxidation is essential for phospholipase C activity and the inositol-trisphosphate-related Ca2+ signal

(2013) A.-M. Domijan et al.   JOURNAL OF CELL SCIENCE

Disturbed brain phospholipid and docosahexaenoic acid metabolism in calcium-independent phospholipase A2-VIA (iPLA2β)-knockout mice

(2012) Yewon Cheon et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Cardiolipin remodeling and the function of tafazzin

(2012) Michael Schlame   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Small amounts of isotope-reinforced polyunsaturated fatty acids suppress lipid autoxidation

(2012) Shauna Hill et al.   FREE RADICAL BIOLOGY AND MEDICINE

Severe disturbance in the Ca2+ signaling in astrocytes from mouse models of human infantile neuroaxonal dystrophy with mutated Pla2g6

(2012) M. Strokin et al.   HUMAN MOLECULAR GENETICS

Four novel rare mutations of PLA2G6 in Chinese population with Parkinson's disease

(2012) Ya-Xing Gui et al.   PARKINSONISM & RELATED DISORDERS

Association of the iPLA2β gene with bipolar disorder and assessment of its interaction with TRPM2 gene polymorphisms

(2012) Chun Xu et al.   PSYCHIATRIC GENETICS

Neuroaxonal Dystrophy in Calcium-Independent Phospholipase A2  Deficiency Results from Insufficient Remodeling and Degeneration of Mitochondrial and Presynaptic Membranes

(2011) G. Beck et al.   JOURNAL OF NEUROSCIENCE

Genetic Ablation of PLA2G6 in Mice Leads to Cerebellar Atrophy Characterized by Purkinje Cell Loss and Glial Cell Activation

(2011) Zhengshan Zhao et al.   PLoS One

Isotopic reinforcement of essential polyunsaturated fatty acids diminishes nigrostriatal degeneration in a mouse model of Parkinson's disease

(2011) Mikhail S. Shchepinov et al.   TOXICOLOGY LETTERS

Isotope-reinforced polyunsaturated fatty acids protect yeast cells from oxidative stress

(2010) Shauna Hill et al.   FREE RADICAL BIOLOGY AND MEDICINE

Dopamine Induces Ca2+Signaling in Astrocytes through Reactive Oxygen Species Generated by Monoamine Oxidase

(2010) Annika Vaarmann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Widespread Lewy body and tau accumulation in childhood and adult onset dystonia-parkinsonism cases with PLA2G6 mutations

(2010) Coro Paisán-Ruiz et al.   NEUROBIOLOGY OF AGING

Catalytic Function of PLA2G6 Is Impaired by Mutations Associated with Infantile Neuroaxonal Dystrophy but Not Dystonia-Parkinsonism

(2010) Laura A. Engel et al.   PLoS One

Critical role of complex III in the early metabolic changes following myocardial infarction

(2009) L. C. Heather et al.   CARDIOVASCULAR RESEARCH

Consequences of long-term oral administration of the mitochondria-targeted antioxidant MitoQ to wild-type mice

(2009) Sergio Rodriguez-Cuenca et al.   FREE RADICAL BIOLOGY AND MEDICINE

Lipid Droplet Biogenesis Induced by Stress Involves Triacylglycerol Synthesis That Depends on Group VIA Phospholipase A2

(2009) Albert Gubern et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of calcium-independent phospholipase A2 in the pathogenesis of Barth syndrome

(2009) A. Malhotra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characterization of PLA2G6 as a locus for dystonia-parkinsonism

(2008) Coro Paisan-Ruiz et al.   ANNALS OF NEUROLOGY

Oxidative stress and mitochondrial dysfunction in neurodegeneration; cardiolipin a critical target?

(2008) Simon Pope et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Starvation resistance is positively correlated with body lipid proportion in five wild caught Drosophila simulans populations

(2008) J. William O. Ballard et al.   JOURNAL OF INSECT PHYSIOLOGY

Neurodegeneration associated with genetic defects in phospholipase A2

(2008) A. Gregory et al.   NEUROLOGY

Cholinergic and glutamatergic alterations beginning at the early stages of Alzheimer disease: participation of the phospholipase A2 enzyme

(2008) Evelin L. Schaeffer et al.   PSYCHOPHARMACOLOGY