Ceramides and ceramide synthases in cancer: Focus on apoptosis and autophagy
Published 2023 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Ceramides and ceramide synthases in cancer: Focus on apoptosis and autophagy
Authors
Keywords
-
Journal
EUROPEAN JOURNAL OF CELL BIOLOGY
Volume 102, Issue 3, Pages 151337
Publisher
Elsevier BV
Online
2023-06-27
DOI
10.1016/j.ejcb.2023.151337
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Role of ceramides in diabetic foot ulcers (Review)
- (2023) Ying Wang et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Temozolomide, Simvastatin and Acetylshikonin Combination Induces Mitochondrial-Dependent Apoptosis in GBM Cells, Which Is Regulated by Autophagy
- (2023) Sima Hajiahmadi et al. Biology-Basel
- Fatty acid transport protein 2 interacts with ceramide synthase 2 to promote ceramide synthesis
- (2022) Jiyoon L. Kim et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Integration of Automatic Text Mining and Genomic and Proteomic Analysis to Unravel Prostate Cancer Biomarkers
- (2022) Tânia Lima et al. JOURNAL OF PROTEOME RESEARCH
- Autophagy in acute myeloid leukemia: a paradoxical role in chemoresistance
- (2022) Aafreen Khan et al. Clinical & Translational Oncology
- Ceramide synthase 6 impacts T-cell allogeneic response and graft-versus-host disease through regulating N-RAS/ERK pathway
- (2022) M. Hanief Sofi et al. LEUKEMIA
- Degradation Mechanism of Autophagy-Related Proteins and Research Progress
- (2022) Yanhui Zhou et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Autophagy: A Key Regulator of Homeostasis and Disease: An Overview of Molecular Mechanisms and Modulators
- (2022) Laura Gómez-Virgilio et al. Cells
- The Role of Endoplasmic Reticulum Stress in Differentiation of Cells of Mesenchymal Origin
- (2022) Ekaterina Turishcheva et al. BIOCHEMISTRY-MOSCOW
- Epigenetic regulation of autophagy in gastrointestinal cancers
- (2022) Saeid Ghavami et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Ceramide Acyl Chain Length and Its Relevance to Intracellular Lipid Regulation
- (2022) Qing Wei Calvin Ho et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Enhancing autophagy in Alzheimer's disease through drug repositioning
- (2022) Mehdi Eshraghi et al. PHARMACOLOGY & THERAPEUTICS
- Lipid metabolism characterization in gastric cancer identifies signatures to predict prognostic and therapeutic responses
- (2022) Jiawei Zeng et al. Frontiers in Genetics
- The Role of Sphingomyelin and Ceramide in Motor Neuron Diseases
- (2022) Gavin McCluskey et al. Journal of Personalized Medicine
- Sphingolipid metabolism and signaling in cardiovascular diseases
- (2022) Sonia Borodzicz-Jażdżyk et al. Frontiers in Cardiovascular Medicine
- PSMA2 knockdown impacts expression of proteins involved in immune and cellular stress responses in human lung cells
- (2022) Mahamud-ur Rashid et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Targeting UGCG Overcomes Resistance to Lysosomal Autophagy Inhibition
- (2022) Vaibhav Jain et al. Cancer Discovery
- Revisiting the role of TRAIL/TRAIL-R in cancer biology and therapy
- (2021) Deepika Singh et al. Future Oncology
- Mechanisms of mitochondrial cell death
- (2021) Shashank Dadsena et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- The application of BH3 mimetics in myeloid leukemias
- (2021) Narissa Parry et al. Cell Death & Disease
- Ceramide induces the apoptosis of non‑small cell lung cancer cells through the Txnip/Trx1 complex
- (2021) Yining Shi et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- The Role of Ceramide Metabolism and Signaling in the Regulation of Mitophagy and Cancer Therapy
- (2021) Megan Sheridan et al. Cancers
- Casein Kinase-1-Alpha Inhibitor (D4476) Sensitizes Microsatellite Instable Colorectal Cancer Cells to 5-Fluorouracil via Authophagy Flux Inhibition
- (2021) Morvarid Siri et al. ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS
- Autophagy in major human diseases
- (2021) Daniel J Klionsky et al. EMBO JOURNAL
- Inhibition of Autophagy Flux Promotes Secretion of Chondroitin Sulfate Proteoglycans in Primary Rat Astrocytes
- (2021) Javad Alizadeh et al. MOLECULAR NEUROBIOLOGY
- Acid ceramidase controls apoptosis and increases autophagy in human melanoma cells treated with doxorubicin
- (2021) Michele Lai et al. Scientific Reports
- Harnessing TRAIL-Induced Apoptosis Pathway for Cancer Immunotherapy and Associated Challenges
- (2021) Ehsan Razeghian et al. Frontiers in Immunology
- Autophagy, Apoptosis, the Unfolded Protein Response, and Lung Function in Idiopathic Pulmonary Fibrosis
- (2021) Pawan Sharma et al. Cells
- Role of AMPK mediated pathways in autophagy and aging
- (2021) Yuchen Ge et al. BIOCHIMIE
- Further exploration of the structure-activity relationship of dual soluble epoxide hydrolase/fatty acid amide hydrolase inhibitors
- (2021) Stephanie Wilt et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Role of ceramide/sphingomyelin (SM) balance regulated through “SM cycle” in cancer
- (2021) Makoto Taniguchi et al. CELLULAR SIGNALLING
- Ceramide Transfer Protein (CERT): An Overlooked Molecular Player in Cancer
- (2021) Long Hoa Chung et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- A novel C-terminal DxRSDxE motif in ceramide synthases involved in dimer formation
- (2021) Jiyoon L. Kim et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The acid sphingomyelinase/ceramide system in COVID-19
- (2021) Johannes Kornhuber et al. MOLECULAR PSYCHIATRY
- Autophagy: The Potential Link between SARS-CoV-2 and Cancer
- (2021) Parham Habibzadeh et al. Cancers
- The Emerging Roles of Autophagy in Human Diseases
- (2021) Yuchen Lei et al. Biomedicines
- Autophagy and bone diseases
- (2021) Marie-Charlotte Trojani et al. JOINT BONE SPINE
- Cell death induced by the ER stressor thapsigargin involves death receptor 5, a non-autophagic function of MAP1LC3B, and distinct contributions from unfolded protein response components
- (2020) Paula Lindner et al. Cell Communication and Signaling
- Autophagy and disease: unanswered questions
- (2020) Ying Yang et al. CELL DEATH AND DIFFERENTIATION
- Ceramide-Induced Cell Death Depends on Calcium and Caspase-Like Activity in Rice
- (2020) Quan-Fang Zhang et al. Frontiers in Plant Science
- C6-ceramide induces salivary adenoid cystic carcinoma cell apoptosis via IP3R-activated UPR and UPR-independent pathways
- (2020) Ling Qiu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Investigating Programmed Cell Death and Tumor Invasion in a Three-Dimensional (3D) Microfluidic Model of Glioblastoma
- (2020) Ehsan Samiei et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The regulatory activity of autophagy in conjunctival fibroblasts and its possible role in vernal keratoconjunctivitis
- (2020) Paola Brun et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Multitargeting Compounds: A Promising Strategy to Overcome Multi-Drug Resistant Tuberculosis
- (2020) Giovanni Stelitano et al. MOLECULES
- Mechanisms, regulation and functions of the unfolded protein response
- (2020) Claudio Hetz et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- IRE1 signaling pathway mediates protective autophagic response against manganese-induced neuronal apoptosis in vivo and in vitro
- (2020) Chang Liu et al. SCIENCE OF THE TOTAL ENVIRONMENT
- Cardio-Metabolic Effects of High-Fat Diets and Their Underlying Mechanisms—A Narrative Review
- (2020) Jibran A. Wali et al. Nutrients
- Association of Aβ with ceramide-enriched astrosomes mediates Aβ neurotoxicity
- (2020) Ahmed Elsherbini et al. Acta Neuropathologica Communications
- Recent advances in multitarget-directed ligands targeting G-protein-coupled receptors
- (2020) Hongguang Ma et al. DRUG DISCOVERY TODAY
- Association of CASP8 polymorphisms and cancer susceptibility: A meta-analysis
- (2020) Mohammad Hashemi et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Crosstalk between Noxa, Bcl-2, and ceramide in mediating p53-dependent apoptosis in Molt-4 human T-cell leukemia
- (2020) Hadile Kobeissy et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- CERS6 required for cell migration and metastasis in lung cancer
- (2020) Motoshi Suzuki et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Pleiotropic effects of statins: A focus on cancer
- (2020) Mazaher Ahmadi et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Ceramide mediates radiation-induced germ cell apoptosis via regulating mitochondria function and MAPK factors in Caenorhabditis elegans
- (2020) Yaning Yang et al. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
- Serine-70 phosphorylated Bcl-2 prevents oxidative stress-induced DNA damage by modulating the mitochondrial redox metabolism
- (2020) Stephen Jun Fei Chong et al. NUCLEIC ACIDS RESEARCH
- Alkaline ceramidase family: The first two decades
- (2020) Ruijuan Xu et al. CELLULAR SIGNALLING
- On the nature of ceramide-mitochondria interactions – Dissection using comprehensive mitochondrial phenotyping
- (2020) Kelsey H. Fisher-Wellman et al. CELLULAR SIGNALLING
- Rational Design of Multitarget-Directed Ligands: Strategies and Emerging Paradigms
- (2019) Junting Zhou et al. JOURNAL OF MEDICINAL CHEMISTRY
- Ceramides bind VDAC2 to trigger mitochondrial apoptosis
- (2019) Shashank Dadsena et al. Nature Communications
- Jnk Activation Is Accompanied By Ceramides And Diacylglycerol Accumulation In Isolated Hepatocytes
- (2019) G. Kravchenko et al. ATHEROSCLEROSIS
- Simvastatin Increases Temozolomide‐induced Cell Death by Targeting the Fusion of Autophagosomes and Lysosomes
- (2019) Shahla Shojaei et al. FEBS Journal
- Mechanisms of simvastatin myotoxicity: The role of autophagy flux inhibition
- (2019) Arya Emami et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- CPTP: A sphingolipid transfer protein that regulates autophagy and inflammasome activation
- (2018) Shrawan Kumar Mishra et al. Autophagy
- Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
- (2018) Lorenzo Galluzzi et al. CELL DEATH AND DIFFERENTIATION
- Sphingolipid regulation of lung epithelial cell mitophagy and necroptosis during cigarette smoke exposure
- (2018) Kenji Mizumura et al. FASEB JOURNAL
- Down-regulation of intracellular anti-apoptotic proteins, particularly c-FLIP by therapeutic agents; the novel view to overcome resistance to TRAIL
- (2018) Ali Hassanzadeh et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Does This Schlank Make Me Look Fat?
- (2018) Bhagirath Chaurasia et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Ceramide Synthase Schlank Is a Transcriptional Regulator Adapting Gene Expression to Energy Requirements
- (2018) Mariangela Sociale et al. Cell Reports
- The combination of a sphingosine kinase 2 inhibitor (ABC294640) and a Bcl-2 inhibitor (ABT-199) displays synergistic anti-myeloma effects in myeloma cells without a t(11;14) translocation
- (2018) Pasupathi Sundaramoorthy et al. Cancer Medicine
- Polypharmacology by Design: A Medicinal Chemist’s Perspective on Multitargeting Compounds
- (2018) Ewgenij Proschak et al. JOURNAL OF MEDICINAL CHEMISTRY
- Ceramide synthase-6 confers resistance to chemotherapy by binding to CD95/Fas in T-cell acute lymphoblastic leukemia
- (2018) Dattesh Verlekar et al. Cell Death & Disease
- Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies
- (2018) Andrew P. Morris et al. Nature Communications
- VDAC2 enables BAX to mediate apoptosis and limit tumor development
- (2018) Hui San Chin et al. Nature Communications
- Autophagy: An Essential Degradation Program for Cellular Homeostasis and Life
- (2018) Yoomi Chun et al. Cells
- Bax, Bak and beyond - mitochondrial performance in apoptosis
- (2017) Aida Peña-Blanco et al. FEBS Journal
- ABC294640, A Novel Sphingosine Kinase 2 Inhibitor, Induces Oncogenic Virus–Infected Cell Autophagic Death and Represses Tumor Growth
- (2017) Lu Dai et al. MOLECULAR CANCER THERAPEUTICS
- Unfolded protein response: Reacting to membrane stress
- (2017) Paulina Strzyz NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Repair, Reuse, Recycle: The Expanding Role of Autophagy in Genome Maintenance
- (2017) Graeme Hewitt et al. TRENDS IN CELL BIOLOGY
- Overexpression of ceramide synthase 1 increases C18-ceramide and leads to lethal autophagy in human glioma
- (2017) Zheng Wang et al. Oncotarget
- Evidence for the involvement of lipid rafts localized at the ER-mitochondria associated membranes in autophagosome formation
- (2016) Tina Garofalo et al. Autophagy
- Targeting FLT3-ITD signaling mediates ceramide-dependent mitophagy and attenuates drug resistance in AML
- (2016) Mohammed Dany et al. BLOOD
- Apoptosis, autophagy and unfolded protein response pathways in Arbovirus replication and pathogenesis
- (2016) Mahmoud Iranpour et al. EXPERT REVIEWS IN MOLECULAR MEDICINE
- Ceramide channels and mitochondrial outer membrane permeability
- (2016) Marco Colombini JOURNAL OF BIOENERGETICS AND BIOMEMBRANES
- Ceramide Synthase 5 Is Essential to Maintain C16:0-Ceramide Pools and Contributes to the Development of Diet-induced Obesity
- (2016) Dominic Gosejacob et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Silencing of CerS6 increases the invasion and glycolysis of melanoma WM35, WM451 and SK28 cell lines via increased GLUT1-induced downregulation of WNT5A
- (2016) YUANYUAN TANG et al. ONCOLOGY REPORTS
- The enigma of ceramide synthase regulation in mammalian cells
- (2016) Marthe-Susanna Wegner et al. PROGRESS IN LIPID RESEARCH
- RIPK3 regulates p62–LC3 complex formation via the caspase-8-dependent cleavage of p62
- (2015) Yu Matsuzawa et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Ceramide channels: destabilization by Bcl-xL and role in apoptosis
- (2015) Kai-Ti Chang et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- The role of CD95 and CD95 ligand in cancer
- (2015) M E Peter et al. CELL DEATH AND DIFFERENTIATION
- Ceramide-Induced Apoptosis in Renal Tubular Cells: A Role of Mitochondria and Sphingosine-1-Phoshate
- (2015) Norishi Ueda INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- UPR, autophagy, and mitochondria crosstalk underlies the ER stress response
- (2015) Daniela Senft et al. TRENDS IN BIOCHEMICAL SCIENCES
- Hepatitis B and C virus-induced hepatitis: Apoptosis, autophagy, and unfolded protein response
- (2015) Behzad Yeganeh WORLD JOURNAL OF GASTROENTEROLOGY
- Cytoplasmic sphingosine-1-phosphate pathway modulates neuronal autophagy
- (2015) Jose Felix Moruno Manchon et al. Scientific Reports
- Bcl-2 family members: Dual regulators of apoptosis and autophagy
- (2014) Beth Levine et al. Autophagy
- Defining and measuring autophagosome flux—concept and reality
- (2014) Ben Loos et al. Autophagy
- Evidence for the involvement of GD3 ganglioside in autophagosome formation and maturation
- (2014) Paola Matarrese et al. Autophagy
- Evolving concepts in cancer therapy through targeting sphingolipid metabolism
- (2014) Jean-Philip Truman et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Airway mesenchymal cell death by mevalonate cascade inhibition: Integration of autophagy, unfolded protein response and apoptosis focusing on Bcl2 family proteins
- (2014) Saeid Ghavami et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Stress-induced ceramide generation and apoptosis via the phosphorylation and activation of nSMase1 by JNK signaling
- (2014) T Yabu et al. CELL DEATH AND DIFFERENTIATION
- Caspases: A Molecular Switch Node in the Crosstalk between Autophagy and Apoptosis
- (2014) Haijian Wu et al. International Journal of Biological Sciences
- Sphingolipid metabolites in inflammatory disease
- (2014) Michael Maceyka et al. NATURE
- Coupling between endocytosis and sphingosine kinase 1 recruitment
- (2014) Hongying Shen et al. NATURE CELL BIOLOGY
- An Overview of Autophagy: Morphology, Mechanism, and Regulation
- (2013) Katherine R. Parzych et al. ANTIOXIDANTS & REDOX SIGNALING
- BAK activation is necessary and sufficient to drive ceramide synthase-dependent ceramide accumulation following inhibition of BCL2-like proteins
- (2013) Levi J. Beverly et al. BIOCHEMICAL JOURNAL
- Ceramide synthases as potential targets for therapeutic intervention in human diseases
- (2013) Joo-Won Park et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Proapoptotic Bax and Bak Proteins Form Stable Protein-permeable Pores of Tunable Size
- (2013) Stephanie Bleicken et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Changes in membrane biophysical properties induced by sphingomyelinase depend on the sphingolipidN-acyl chain
- (2013) Sandra N. Pinto et al. JOURNAL OF LIPID RESEARCH
- Rab11 facilitates cross-talk between autophagy and endosomal pathway through regulation of Hook localization
- (2013) Zsuzsanna Szatmári et al. MOLECULAR BIOLOGY OF THE CELL
- Autophagy in Human Health and Disease
- (2013) Augustine M.K. Choi et al. NEW ENGLAND JOURNAL OF MEDICINE
- The mitochondrial permeability transition pore: a mystery solved?
- (2013) Paolo Bernardi Frontiers in Physiology
- Regulation of Autophagy by Sphingolipids
- (2012) Carmen Bedia et al. Anti-Cancer Agents in Medicinal Chemistry
- Cleavage of Atg3 protein by caspase-8 regulates autophagy during receptor-activated cell death
- (2012) Ozlem Oral et al. APOPTOSIS
- Bax and Bcl-xL exert their regulation on different sites of the ceramide channel
- (2012) Meenu N. Perera et al. BIOCHEMICAL JOURNAL
- Ceramide synthases at the centre of sphingolipid metabolism and biology
- (2012) Thomas D. Mullen et al. BIOCHEMICAL JOURNAL
- Ceramide channels: Influence of molecular structure on channel formation in membranes
- (2012) Meenu N. Perera et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Autophagy regulates trans fatty acid-mediated apoptosis in primary cardiac myofibroblasts
- (2012) Saeid Ghavami et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Mitophagy: mechanisms, pathophysiological roles, and analysis
- (2012) Wen-Xing Ding et al. BIOLOGICAL CHEMISTRY
- The Dynamics of Bax Channel Formation: Influence of Ionic Strength
- (2012) Vidyaramanan Ganesan et al. BIOPHYSICAL JOURNAL
- Proteolysis of Ambra1 during apoptosis has a role in the inhibition of the autophagic pro-survival response
- (2012) V Pagliarini et al. CELL DEATH AND DIFFERENTIATION
- Long chain ceramides and very long chain ceramides have opposite effects on human breast and colon cancer cell growth
- (2012) Daniela Hartmann et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Dihydroceramide delays cell cycle G1/S transition via activation of ER stress and induction of autophagy
- (2012) Vincenzo Gagliostro et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Regulation of Autophagy and Its Associated Cell Death by “Sphingolipid Rheostat”
- (2012) Makoto Taniguchi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Modulation of Ceramide Synthase Activity via Dimerization
- (2012) Elad L. Laviad et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TBC1D14 regulates autophagosome formation via Rab11- and ULK1-positive recycling endosomes
- (2012) Andrea Longatti et al. JOURNAL OF CELL BIOLOGY
- Atg9 vesicles are an important membrane source during early steps of autophagosome formation
- (2012) Hayashi Yamamoto et al. JOURNAL OF CELL BIOLOGY
- Ceramide synthase 5 mediates lipid-induced autophagy and hypertrophy in cardiomyocytes
- (2012) Sarah Brice Russo et al. JOURNAL OF CLINICAL INVESTIGATION
- Ablation of ceramide synthase 2 strongly affects biophysical properties of membranes
- (2012) Liana C. Silva et al. JOURNAL OF LIPID RESEARCH
- Sphingolipids: regulators of crosstalk between apoptosis and autophagy
- (2012) Megan M. Young et al. JOURNAL OF LIPID RESEARCH
- TRAIL induces autophagic protein cleavage through caspase activation in melanoma cell lines under arginine deprivation
- (2012) Min You et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Ceramide targets autophagosomes to mitochondria and induces lethal mitophagy
- (2012) R David Sentelle et al. Nature Chemical Biology
- Mitochondrial Apoptosis-Induced Channel (MAC) Function Triggers a Bax/Bak-Dependent Bystander Effect
- (2011) Pablo M. Peixoto et al. AMERICAN JOURNAL OF PATHOLOGY
- A novel mechanism of dasatinib-induced apoptosis in chronic myeloid leukemia; ceramide synthase and ceramide clearance genes
- (2011) Emel B. Gencer et al. ANNALS OF HEMATOLOGY
- Ceramide synthase 4 andde novoproduction of ceramides with specific N-acyl chain lengths are involved in glucolipotoxicity-induced apoptosis of INS-1 β-cells
- (2011) Julien Véret et al. BIOCHEMICAL JOURNAL
- Effect of ceramide structure on membrane biophysical properties: The role of acyl chain length and unsaturation
- (2011) Sandra N. Pinto et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Inhibitors of specific ceramide synthases
- (2011) Susanne Schiffmann et al. BIOCHIMIE
- The Beclin 1 network regulates autophagy and apoptosis
- (2011) R Kang et al. CELL DEATH AND DIFFERENTIATION
- Autophagy in the Cellular Energetic Balance
- (2011) Rajat Singh et al. Cell Metabolism
- Bioinformatics and Systems Biology of the Lipidome
- (2011) Shankar Subramaniam et al. CHEMICAL REVIEWS
- Loss of ceramide synthase 3 causes lethal skin barrier disruption
- (2011) Richard Jennemann et al. HUMAN MOLECULAR GENETICS
- Acyl Chain Specificity of Ceramide Synthases Is Determined within a Region of 150 Residues in the Tram-Lag-CLN8 (TLC) Domain
- (2011) Rotem Tidhar et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Acid Ceramidase Expression Modulates the Sensitivity of A375 Melanoma Cells to Dacarbazine
- (2011) Carmen Bedia et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Encephalopathy Caused by Ablation of Very Long Acyl Chain Ceramide Synthesis May Be Largely Due to Reduced Galactosylceramide Levels
- (2011) Oshrit Ben-David et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Alteration of Ceramide Synthase 6/C16-Ceramide Induces Activating Transcription Factor 6-mediated Endoplasmic Reticulum (ER) Stress and Apoptosis via Perturbation of Cellular Ca2+and ER/Golgi Membrane Network
- (2011) Can E. Senkal et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Dihydroceramide-based Response to Hypoxia
- (2011) Cecilia M. Devlin et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Roles of ceramide synthase and ceramide clearence genes in nilotinib-induced cell death in chronic myeloidleukemia cells
- (2011) Aylin Camgoz et al. LEUKEMIA & LYMPHOMA
- Mitochondrial Ceramide-Rich Macrodomains Functionalize Bax upon Irradiation
- (2011) Hyunmi Lee et al. PLoS One
- Ceramide and activated Bax act synergistically to permeabilize the mitochondrial outer membrane
- (2010) Vidyaramanan Ganesan et al. APOPTOSIS
- Celecoxib-induced apoptosis is enhanced by ABT-737 and by inhibition of autophagy in human colorectal cancer cells
- (2010) Shengbing Huang et al. Autophagy
- Activation of ceramide synthase 6 by celecoxib leads to a selective induction of C16:0-ceramide
- (2010) Susanne Schiffmann et al. BIOCHEMICAL PHARMACOLOGY
- Ceramide channels and their role in mitochondria-mediated apoptosis
- (2010) Marco Colombini BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Involvement of caspase-9 in autophagy-mediated cell survival pathway
- (2010) Hyo-Soon Jeong et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Vorinostat and sorafenib increase ER stress, autophagy and apoptosis via ceramide-dependent CD95 and PERK activation
- (2010) Margaret A. Park et al. CANCER BIOLOGY & THERAPY
- A new take on ceramide: Starving cells by cutting off the nutrient supply
- (2010) Garret G. Guenther et al. CELL CYCLE
- Ceramide synthases 2, 5, and 6 confer distinct roles in radiation-induced apoptosis in HeLa cells
- (2010) Judith Mesicek et al. CELLULAR SIGNALLING
- Altered lipid content inhibits autophagic vesicular fusion
- (2010) Hiroshi Koga et al. FASEB JOURNAL
- Sphingolipids and cancer: ceramide and sphingosine-1-phosphate in the regulation of cell death and drug resistance
- (2010) Suriyan Ponnusamy et al. Future Oncology
- Mammalian ceramide synthases
- (2010) Michal Levy et al. IUBMB LIFE
- A Critical Role for Ceramide Synthase 2 in Liver Homeostasis
- (2010) Yael Pewzner-Jung et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mitochondrially targeted ceramides preferentially promote autophagy, retard cell growth, and induce apoptosis
- (2010) Qi Hou et al. JOURNAL OF LIPID RESEARCH
- Selective knockdown of ceramide synthases reveals complex interregulation of sphingolipid metabolism
- (2010) Thomas D. Mullen et al. JOURNAL OF LIPID RESEARCH
- Eaten alive: a history of macroautophagy
- (2010) Zhifen Yang et al. NATURE CELL BIOLOGY
- Autophagy is increased in prostate cancer cells overexpressing acid ceramidase and enhances resistance to C6 ceramide
- (2010) L S Turner et al. PROSTATE CANCER AND PROSTATIC DISEASES
- Caspase-mediated cleavage of Beclin-1 inactivates Beclin-1-induced autophagy and enhances apoptosis by promoting the release of proapoptotic factors from mitochondria
- (2010) E Wirawan et al. Cell Death & Disease
- Ceramide-induced autophagy: To junk or to protect cells?
- (2009) Sophie Pattingre et al. Autophagy
- Increased ceramide synthase 2 and 6 mRNA levels in breast cancer tissues and correlation with sphingosine kinase expression
- (2009) Racheli Erez-Roman et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Disruption of ceramide synthesis by CerS2 down-regulation leads to autophagy and the unfolded protein response
- (2009) Stefka D. Spassieva et al. BIOCHEMICAL JOURNAL
- Starvation in the midst of plenty: making sense of ceramide-induced autophagy by analysing nutrient transporter expression
- (2009) Aimee L. Edinger BIOCHEMICAL SOCIETY TRANSACTIONS
- Ceramide synthase 1 is regulated by proteasomal mediated turnover
- (2009) Priya Sridevi et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Dihydroceramide intracellular increase in response to resveratrol treatment mediates autophagy in gastric cancer cells
- (2009) Paola Signorelli et al. CANCER LETTERS
- Ceramide synthases and ceramide levels are increased in breast cancer tissue
- (2009) Susanne Schiffmann et al. CARCINOGENESIS
- Antiapoptotic roles of ceramide-synthase-6-generated C16-ceramide via selective regulation of the ATF6/CHOP arm of ER-stress-response pathways
- (2009) Can E. Senkal et al. FASEB JOURNAL
- Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells
- (2009) María Salazar et al. JOURNAL OF CLINICAL INVESTIGATION
- Ceramide and neurodegeneration: Susceptibility of neurons and oligodendrocytes to cell damage and death
- (2009) Arundhati Jana et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Sorafenib and Vorinostat Kill Colon Cancer Cells by CD95-Dependent and -Independent Mechanisms
- (2009) T. Walker et al. MOLECULAR PHARMACOLOGY
- Ceramide synthase 6 modulates TRAIL sensitivity and nuclear translocation of active caspase-3 in colon cancer cells
- (2009) S White-Gilbertson et al. ONCOGENE
- Anti-ceramidase LCL385 acutely reduces BCL-2 expression in the hippocampus but is not associated with an increase of learned helplessness in rats
- (2008) Z NAHAS et al. BEHAVIOURAL BRAIN RESEARCH
- Protein phosphatase 2A inactivates Bcl2's antiapoptotic function by dephosphorylation and up-regulation of Bcl2-p53 binding
- (2008) X. Deng et al. BLOOD
- Autophagy in the Pathogenesis of Disease
- (2008) Beth Levine et al. CELL
- Mitochondrial Autophagy Is an HIF-1-dependent Adaptive Metabolic Response to Hypoxia
- (2008) Huafeng Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Ceramide Generated by Sphingomyelin Hydrolysis and the Salvage Pathway Is Involved in Hypoxia/Reoxygenation-induced Bax Redistribution to Mitochondria in NT-2 Cells
- (2008) Junfei Jin et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Male Germ Cells Require Polyenoic Sphingolipids with Complex Glycosylation for Completion of Meiosis
- (2008) Mariona Rabionet et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Role of JNK1-dependent Bcl-2 Phosphorylation in Ceramide-induced Macroautophagy
- (2008) Sophie Pattingre et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Anti-apoptotic Bcl-2 Family Proteins Disassemble Ceramide Channels
- (2008) Leah J. Siskind et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The selective COX-2 inhibitor celecoxib modulates sphingolipid synthesis
- (2008) Susanne Schiffmann et al. JOURNAL OF LIPID RESEARCH
- 2-Hydroxy-ceramide synthesis by ceramide synthase family: enzymatic basis for the preference of FA chain length
- (2008) Yukiko Mizutani et al. JOURNAL OF LIPID RESEARCH
- Multi-target-Directed Ligands To Combat Neurodegenerative Diseases
- (2008) Andrea Cavalli et al. JOURNAL OF MEDICINAL CHEMISTRY
- Acid Ceramidase Upregulation in Prostate Cancer Cells Confers Resistance to Radiation: AC Inhibition, a Potential Radiosensitizer
- (2008) Ayman EM Mahdy et al. MOLECULAR THERAPY
- Autophagy fights disease through cellular self-digestion
- (2008) Noboru Mizushima et al. NATURE
- The pivotal role of c-Jun NH2-terminal kinase-mediated Beclin 1 expression during anticancer agents-induced autophagy in cancer cells
- (2008) D-D Li et al. ONCOGENE
- Ceramide starves cells to death by downregulating nutrient transporter proteins
- (2008) G. G. Guenther et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started