A Critical Role for Ceramide Synthase 2 in Liver Homeostasis

A Critical Role for Ceramide Synthase 2 in Liver Homeostasis

(2010) Yael Pewzner-Jung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Disruption of ceramide synthesis by CerS2 down-regulation leads to autophagy and the unfolded protein response

(2009) Stefka D. Spassieva et al.   BIOCHEMICAL JOURNAL

Ceramide synthases and ceramide levels are increased in breast cancer tissue

(2009) Susanne Schiffmann et al.   CARCINOGENESIS

Adult Ceramide Synthase 2 (CERS2)-deficient Mice Exhibit Myelin Sheath Defects, Cerebellar Degeneration, and Hepatocarcinomas

(2009) Silke Imgrund et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial degeneration and not apoptosis is the primary cause of embryonic lethality in ceramide transfer protein mutant mice

(2009) Xin Wang et al.   JOURNAL OF CELL BIOLOGY

Sumoylated PPARα mediates sex-specific gene repression and protects the liver from estrogen-induced toxicity in mice

(2009) Nicolas Leuenberger et al.   JOURNAL OF CLINICAL INVESTIGATION

Sorafenib and Vorinostat Kill Colon Cancer Cells by CD95-Dependent and -Independent Mechanisms

(2009) T. Walker et al.   MOLECULAR PHARMACOLOGY

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Protection of C. elegans from Anoxia by HYL-2 Ceramide Synthase

(2009) V. Menuz et al.   SCIENCE

Ontologizer 2.0--a multifunctional tool for GO term enrichment analysis and data exploration

(2008) S. Bauer et al.   BIOINFORMATICS

BioVenn – a web application for the comparison and visualization of biological lists using area-proportional Venn diagrams

(2008) Tim Hulsen et al.   BMC GENOMICS

Role of very long fatty acid-containing glycosphingolipids in membrane organization and cell signaling: the model of lactosylceramide in neutrophils

(2008) Sandro Sonnino et al.   GLYCOCONJUGATE JOURNAL

Ceramide Generated by Sphingomyelin Hydrolysis and the Salvage Pathway Is Involved in Hypoxia/Reoxygenation-induced Bax Redistribution to Mitochondria in NT-2 Cells

(2008) Junfei Jin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Liver gene expression analysis reveals endoplasmic reticulum stress and metabolic dysfunction in SCD1-deficient mice fed a very low-fat diet

(2008) Matthew T. Flowers et al.   PHYSIOLOGICAL GENOMICS

De novo N-palmitoylsphingosine synthesis is the major biochemical mechanism of ceramide accumulation following p53 up-regulation

(2008) Shoghag Panjarian et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Ceramide Biogenesis Is Required for Radiation-Induced Apoptosis in the Germ Line of C. elegans

(2008) X. Deng et al.   SCIENCE