Loss of ceramide synthase 3 causes lethal skin barrier disruption

LC/MS analysis of stratum corneum lipids: ceramide profiling and discovery

(2011) Jeroen van Smeden et al.   JOURNAL OF LIPID RESEARCH

An Innate Role for IL-17

(2011) M. Dominguez-Villar et al.   SCIENCE

Chronic Mucocutaneous Candidiasis in Humans with Inborn Errors of Interleukin-17 Immunity

(2011) A. Puel et al.   SCIENCE

Self-Improvement of Keratinocyte Differentiation Defects During Skin Maturation in ABCA12-Deficient Harlequin Ichthyosis Model Mice

(2010) Teruki Yanagi et al.   AMERICAN JOURNAL OF PATHOLOGY

Inborn errors of mucocutaneous immunity to Candida albicans in humans: a role for IL-17 cytokines?

(2010) Anne Puel et al.   CURRENT OPINION IN IMMUNOLOGY

ABCA12 mutations and autosomal recessive congenital ichthyosis: A review of genotype/phenotype correlations and of pathogenetic conceptsa

(2010) Masashi Akiyama   HUMAN MUTATION

Neutral Lipid Storage Leads to Acylceramide Deficiency, Likely Contributing to the Pathogenesis of Dorfman–Chanarin Syndrome

(2010) Yoshikazu Uchida et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Changes in the Ceramide Profile of Atopic Dermatitis Patients

(2010) Junko Ishikawa et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Revised nomenclature and classification of inherited ichthyoses: Results of the First Ichthyosis Consensus Conference in Sorèze 2009

(2010) Vinzenz Oji et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Mutations in the Fatty Acid Transport Protein 4 Gene Cause the Ichthyosis Prematurity Syndrome

(2009) Joakim Klar et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Ceramide biosynthesis in keratinocyte and its role in skin function

(2009) Yukiko Mizutani et al.   BIOCHIMIE

Phytosphingosine kills Candida albicans by disrupting its cell membrane

(2009) Enno C.I. Veerman et al.   BIOLOGICAL CHEMISTRY

Disruption of blood-testis barrier dynamics in ether-lipid-deficient mice

(2009) Dorde Komljenovic et al.   CELL AND TISSUE RESEARCH

Very long chain sphingolipids: Tissue expression, function and synthesis

(2009) Roger Sandhoff   FEBS LETTERS

Filaggrin deficiency confers a paracellular barrier abnormality that reduces inflammatory thresholds to irritants and haptens

(2009) Tiffany C. Scharschmidt et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Growth Retardation, Impaired Triacylglycerol Catabolism, Hepatic Steatosis, and Lethal Skin Barrier Defect in Mice Lacking Comparative Gene Identification-58 (CGI-58)

(2009) Franz P. W. Radner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Filaggrin in the frontline: role in skin barrier function and disease

(2009) A. Sandilands et al.   JOURNAL OF CELL SCIENCE

Interpreting Neonatal Lethal Phenotypes in Mouse Mutants: Insights Into Gene Function and Human Diseases

(2009) Benjamin Turgeon et al.   PHYSIOLOGICAL REVIEWS

Protection of C. elegans from Anoxia by HYL-2 Ceramide Synthase

(2009) V. Menuz et al.   SCIENCE

Harlequin ichthyosis model mouse reveals alveolar collapse and severe fetal skin barrier defects

(2008) T. Yanagi et al.   HUMAN MOLECULAR GENETICS

ABCA12 Maintains the Epidermal Lipid Permeability Barrier by Facilitating Formation of Ceramide Linoleic Esters

(2008) Ying Zuo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Male Germ Cells Require Polyenoic Sphingolipids with Complex Glycosylation for Completion of Meiosis

(2008) Mariona Rabionet et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Omega-O-acylceramide, a lipid essential for mammalian survival

(2008) Yoshikazu Uchida et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Thematic review series: Skin Lipids.Pathogenesis of permeability barrier abnormalities in the ichthyoses: inherited disorders of lipid metabolism

(2008) Peter M. Elias et al.   JOURNAL OF LIPID RESEARCH