SARS-CoV-2 infection and dysregulation of nuclear factor erythroid-2-related factor 2 (Nrf2) pathway

SARS‐COV‐2 infection and Parkinson's disease: Possible links and perspectives

(2023) Hayder M. Al‐kuraishy et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Receptor-dependent effects of sphingosine-1-phosphate (S1P) in COVID-19: the black side of the moon

(2023) Hayder M. Al-kuraishy et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Heparanase is the possible link between monkeypox and Covid-19: robust candidature in the mystic and present perspective

(2023) Hayder M. Al-Kuraishy et al.   AMB Express

Hippo-YAP signaling and SARS-CoV-2 infection: a new mechanistic pathway

(2023) Hayder M. Al-Kuraishy et al.   CELL STRESS & CHAPERONES

NF‐κB/NLRP3 inflammasome axis and risk of Parkinson's disease in Type 2 diabetes mellitus: A narrative review and new perspective

(2023) Mohammed Alrouji et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Immunological interactions in helminths‐SARS CoV‐2 coinfection: Could old enemy be a friend today?

(2023) Mohammed Alrouji et al.   PARASITE IMMUNOLOGY

Comparison of Vitamin D and Resveratrol Performances in COVID-19

(2023) Cristina Russo et al.   Nutrients

Long COVID and risk of erectile dysfunction in recovered patients from mild to moderate COVID-19

(2023) Hayder M. Al-kuraishy et al.   Scientific Reports

The potential therapeutic effect of statins in multiple sclerosis: beneficial or detrimental effects

(2023) Hayder M. Al-Kuraishy et al.   INFLAMMOPHARMACOLOGY

Potential role of tirzepatide towards Covid-19 infection in diabetic patients: a perspective approach

(2023) Gaber El-Saber Batiha et al.   INFLAMMOPHARMACOLOGY

SARS-CoV-2 Inhibits NRF2-Mediated Antioxidant Responses in Airway Epithelial Cells and in the Lung of a Murine Model of Infection

(2023) Yue Qu et al.   Microbiology Spectrum

Mixed storm in SARS‐CoV‐2 infection: A narrative review and new term in the Covid‐19 era

(2023) Basil Mohammed Alomair et al.   Immunity Inflammation and Disease

The potential role of scavenger receptor B type I (SR‐BI) in SARS‐CoV‐2 infection

(2023) Luay Alkazmi et al.   Immunity Inflammation and Disease

SARS‐CoV‐2 induced HDL dysfunction may affect the host's response to and recovery from COVID‐19

(2023) Hayder M. Al‐kuraishy et al.   Immunity Inflammation and Disease

The potential role of SARS‐CoV‐2 infection in acute coronary syndrome and type 2 myocardial infarction (T2MI): Intertwining spread

(2023) Aseel Awad Alsaidan et al.   Immunity Inflammation and Disease

Gentisic acid protects against diabetic nephropathy in Nicotinamide-Streptozotocin administered male mice by attenuating oxidative stress and inflammation: The role of miR-200a/Keap1/Nrf2 pathway, renin-angiotensin system (RAS) and NF-кB

(2023) Reza Noei Razliqi et al.   CHEMICO-BIOLOGICAL INTERACTIONS

The probable role and therapeutic potential of the PI3K/AKT signaling pathway in SARS-CoV-2 induced coagulopathy

(2022) Mohammad Rafi Khezri et al.   CELLULAR & MOLECULAR BIOLOGY LETTERS

Andrographolide Derivatives Target the KEAP1/NRF2 Axis and Possess Potent Anti‐SARS‐CoV‐2 Activity

(2022) Bianca Schulte et al.   ChemMedChem

The Prospective Effect of Allopurinol on the Oxidative Stress Index and Endothelial Dysfunction in Covid-19

(2022) Hayder M. Al-kuraishy et al.   INFLAMMATION

Oxidative stress and decreased Nrf2 level in pediatric patients with COVID‐19

(2022) Hüseyin Gümüş et al.   JOURNAL OF MEDICAL VIROLOGY

The crucial role of prolactin-lactogenic hormone in Covid-19

(2022) Hayder M. Al-Kuraishy et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

A New Butyrate Releaser Exerts a Protective Action against SARS-CoV-2 Infection in Human Intestine

(2022) Lorella Paparo et al.   MOLECULES

ADAM Metalloproteinase Domain 17 Regulates Cholestasis-Associated Liver Injury and Sickness Behavior Development in Mice

(2022) Wagdi Almishri et al.   Frontiers in Immunology

Nrf2 Is Required for Optimal Alveolar-Macrophage-Mediated Apoptotic Neutrophil Clearance after Oxidant Injury

(2022) Narsa M. Reddy et al.   Antioxidants

Nrf2 activation reprograms macrophage intermediary metabolism and suppresses the type I interferon response

(2022) Dylan G. Ryan et al.   iScience

The possible role of ursolic acid in Covid-19: A real game changer

(2022) Hayder M. Al-kuraishy et al.   Clinical Nutrition ESPEN

mTOR substrate phosphorylation in growth control

(2022) Stefania Battaglioni et al.   CELL

AUF1 protects against ferroptosis to alleviate sepsis-induced acute lung injury by regulating NRF2 and ATF3

(2022) Yichun Wang et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Favipiravir in SARS-CoV-2 infection: Is it Worthwhile?

(2022) Gaber El-Saber Batiha et al.   COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING

Neutrophil Extracellular Traps (NETs) and Covid-19: A new frontiers for therapeutic modality

(2022) Hayder M. Al-Kuraishy et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Targeting Nrf2-Mediated Oxidative Stress Response in Traumatic Brain Injury: Therapeutic Perspectives of Phytochemicals

(2022) An-Guo Wu et al.   Oxidative Medicine and Cellular Longevity

Selinexor and COVID-19: The Neglected Warden

(2022) Gomaa Mostafa-Hedeab et al.   Frontiers in Pharmacology

A raising dawn of pentoxifylline in management of inflammatory disorders in Covid-19

(2022) Gomaa Mostafa-Hedeab et al.   INFLAMMOPHARMACOLOGY

COVID-19 and corticosteroids: a narrative review

(2022) Gaber El-Saber Batiha et al.   INFLAMMOPHARMACOLOGY

High-mobility group box 1 (HMGB1) in COVID-19: extrapolation of dangerous liaisons

(2022) Hayder M. Al-kuraishy et al.   INFLAMMOPHARMACOLOGY

Sodium thiosulfate acts as a hydrogen sulfide mimetic to prevent intimal hyperplasia via inhibition of tubulin polymerisation

(2022) Diane Macabrey et al.   EBioMedicine

Vinpocetine is the forthcoming adjuvant agent in the management of COVID-19

(2022) Hayder M Al-kuraishy et al.   Future Science OA

Hemolytic anemia in COVID-19

(2022) Hayder M. Al-kuraishy et al.   ANNALS OF HEMATOLOGY

Central effects of Ivermectin in alleviation of Covid-19-induced dysautonomia

(2022) Hayder M. Al-kuraishy et al.   CURRENT DRUG TARGETS

Calprotectin: the link between acute lung injury and gastrointestinal injury in Covid-19: Ban or boon

(2022) Hayder M. Al-kuraishy et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

SARS-CoV-2 infection and C1-esterase inhibitor: Camouflage pattern and new perspective

(2022) Hayder M. Al-kuraishy et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Targeting and Modulation of the Natriuretic Peptide System in Covid-19: A single or double-edged effect?

(2022) Hayder M. Al-kuraishy et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Fenofibrate for COVID-19 and related complications as an approach to improve treatment outcomes: the missed key for Holy Grail

(2022) Shadi Salem Alkhayyat et al.   INFLAMMATION RESEARCH

Ursolic acid and SARS-CoV-2 infection: a new horizon and perspective

(2022) Hayder M. Al-kuraishy et al.   INFLAMMOPHARMACOLOGY

The Spike Protein of SARS-CoV-2 Impairs Lipid Metabolism and Increases Susceptibility to Lipotoxicity: Implication for a Role of Nrf2

(2022) Vi Nguyen et al.   Cells

Changes in the Blood Viscosity in Patients With SARS-CoV-2 Infection

(2022) Hayder M. Al-kuraishy et al.   Frontiers in Medicine

An insight into the placental growth factor (PlGf)/angii axis in Covid-19: a detrimental intersection

(2022) Hayder M. Al-Kuraishy et al.   Biotechnology & Genetic Engineering Reviews

Prostaglandins and non-steroidal anti-inflammatory drugs in Covid-19

(2022) Hayder M. Al-Kuraishy et al.   Biotechnology & Genetic Engineering Reviews

5-HT/CGRP pathway and Sumatriptan role in Covid-19

(2022) Hayder M. Al-Kuraishy et al.   Biotechnology & Genetic Engineering Reviews

Mechanisms underlying Nrf2 nuclear translocation by non-lethal levels of hydrogen peroxide: p38 MAPK-dependent neutral sphingomyelinase2 membrane trafficking and ceramide/PKCζ/CK2 signaling

(2022) Tetsuro Ishii et al.   FREE RADICAL BIOLOGY AND MEDICINE

Nitazoxanide and COVID-19: A review

(2022) Hayder M. Al-kuraishy et al.   MOLECULAR BIOLOGY REPORTS

Oxytocin in diabetic Covid-19 patients: a new perspective

(2022) Hayder M. Al-kuraishy et al.   NATURAL PRODUCT RESEARCH

Citicoline and COVID-19: vis-à-vis conjectured

(2022) Hayder M. Al-kuraishy et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Pathophysiology of Post-COVID syndromes: a new perspective

(2022) Gaber El-Saber Batiha et al.   Virology Journal

Roxadustat for SARS-CoV-2 Infection: Old Signaling Raised New Hopes

(2022) Luay Alkazmi et al.   DRUGS IN R&D

Is sitagliptin effective for SARS-CoV-2 infection: false or true prophecy?

(2022) Basil Mohammed Alomair et al.   INFLAMMOPHARMACOLOGY

COVID-19 and diabetes: will novel drugs for diabetes help in COVID-19?

(2022) Pranav Kumar Prabhakar et al.   Current Molecular Pharmacology

The potential molecular implications of adiponectin in the evolution of SARS-CoV-2: Inbuilt tendency

(2022) Hayder M. Al-Kuraishy et al.   JOURNAL OF KING SAUD UNIVERSITY SCIENCE

The Potential Role of Growth Differentiation Factor 15 in COVID-19: A Corollary Subjective Effect or Not?

(2022) Ahmad O. Babalghith et al.   Diagnostics

Role of Neuropilin 1 in COVID-19 Patients with Acute Ischemic Stroke

(2022) Asma W. Al-Thomali et al.   Biomedicines

Montelukast and Acute Coronary Syndrome: The Endowed Drug

(2022) Basil Mohammed Alomair et al.   Pharmaceuticals

Cholinergic dysfunction in COVID-19: frantic search and hoping for the best

(2022) Eman Hassan Nadwa et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

A Potential Link Between Visceral Obesity and Risk of Alzheimer’s Disease

(2022) Hayder M. Al-Kuraishy et al.   NEUROCHEMICAL RESEARCH

Targeting of neuroinflammation by glibenclamide in Covid-19: old weapon from arsenal

(2022) Gaber El-Saber Batiha et al.   INFLAMMOPHARMACOLOGY

Potential Therapeutic Benefits of Metformin Alone and in Combination with Sitagliptin in the Management of Type 2 Diabetes Patients with COVID-19

(2022) Hayder M. Al-Kuraishy et al.   Pharmaceuticals

Common NLRP3 inflammasome inhibitors and Covid-19: Divide and conquer

(2022) Gaber El-Saber Batiha et al.   Scientific African

Quercetin Alleviates Oxidative Damage by Activating Nuclear Factor Erythroid 2-Related Factor 2 Signaling in Porcine Enterocytes

(2021) Hai Jia et al.   Nutrients

Nrf2 Activation Sensitizes K-Ras Mutant Pancreatic Cancer Cells to Glutaminase Inhibition

(2021) Shin Hamada et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Divulging the Intricacies of Crosstalk Between NF-Kb and Nrf2-Keap1 Pathway in Neurological Complications of COVID-19

(2021) Ranjana Bhandari et al.   MOLECULAR NEUROBIOLOGY

Therapeutic Potential of Resveratrol in COVID-19-Associated Hemostatic Disorders

(2021) Roberta Giordo et al.   MOLECULES

Antioxidants and pentoxifylline as coadjuvant measures to standard therapy to improve prognosis of patients with pneumonia by COVID-19

(2021) Adrián Palacios Chavarria et al.   Computational and Structural Biotechnology Journal

Pharmacotherapy against Oxidative Stress in Chronic Kidney Disease: Promising Small Molecule Natural Products Targeting Nrf2-HO-1 Signaling

(2021) Md Jamal Uddin et al.   Antioxidants

COVID-19 and Risk of Acute Ischemic Stroke and Acute Lung Injury in Patients With Type II Diabetes Mellitus: The Anti-inflammatory Role of Metformin

(2021) Hayder M. Al-kuraishy et al.   Frontiers in Medicine

Case Report: Hyperbilirubinemia in Gilbert Syndrome Attenuates Covid-19-Induced Metabolic Disturbances

(2021) Hayder M. Al-kuraishy et al.   Frontiers in Cardiovascular Medicine

Role of leukotriene pathway and montelukast in pulmonary and extrapulmonary manifestations of Covid-19: The enigmatic entity

(2021) Hayder M. Al-kuraishy et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Effects of SARS-CoV-2 on Cardiovascular System: The Dual Role of Angiotensin-Converting Enzyme 2 (ACE2) as the Virus Receptor and Homeostasis Regulator-Review

(2021) Aneta Aleksova et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Chrysin Ameliorates Sepsis-Induced Cardiac Dysfunction Through Upregulating Nfr2/Heme Oxygenase 1 Pathway

(2021) Li Xingyue et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Ashwagandha (Withania somnifera) root extract attenuates hepatic and cognitive deficits in thioacetamide-induced rat model of hepatic encephalopathy via induction of Nrf2/HO-1 and mitigation of NF-kB/MAPK signaling pathways

(2021) Heba M.A. Khalil et al.   JOURNAL OF ETHNOPHARMACOLOGY

Role of pirfenidone in TGF-β pathways and other inflammatory pathways in acute respiratory syndrome coronavirus 2 (SARS-Cov-2) infection: a theoretical perspective

(2021) Seyed Hootan Hamidi et al.   Pharmacological Reports

Sulforaphane inhibits the expression of interleukin-6 and interleukin-8 induced in bronchial epithelial IB3-1 cells by exposure to the SARS-CoV-2 Spike protein

(2021) Jessica Gasparello et al.   PHYTOMEDICINE

Soluble receptor for advanced glycation end products (sRAGE) as a biomarker of COVID-19 disease severity and indicator of the need for mechanical ventilation, ARDS and mortality

(2021) Adeline Lim et al.   Annals of Intensive Care

Pleiotropic Effects of Tetracyclines in the Management of COVID-19: Emerging Perspectives

(2021) Hayder M. Al-kuraishy et al.   Frontiers in Pharmacology

The Looming Effects of Estrogen in Covid-19: A Rocky Rollout

(2021) Hayder M. Al-kuraishy et al.   Frontiers in Nutrition

The role of understudied post‐translational modifications for the behavior and function of Signal Transducer and Activator of Transcription 3

(2021) Mickael Diallo et al.   FEBS Journal

Phase I study of mTORC1/2 inhibitor sapanisertib (TAK-228) in combination with metformin in patients (pts) with mTOR/AKT/PI3K pathway alterations and advanced solid malignancies.

(2021) Niamh Coleman et al.   JOURNAL OF CLINICAL ONCOLOGY

Nuclear IL-33 Plays an Important Role in IL-31‒Mediated Downregulation of FLG, Keratin 1, and Keratin 10 by Regulating Signal Transducer and Activator of Transcription 3 Activation in Human Keratinocytes

(2021) Xiuju Dai et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The potential role of neopterin in Covid-19: a new perspective

(2021) Hayder M. Al-kuraishy et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Anti-inflammatory Therapy by Cholinergic and Purinergic Modulation in Multiple Sclerosis Associated with SARS-CoV-2 Infection

(2021) Júlia Leão Batista Simões et al.   MOLECULAR NEUROBIOLOGY

Covid-19 and development of heart failure: mystery and truth

(2021) Hope Onohuean et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Formononetin attenuates H2O2-induced cell death through decreasing ROS level by PI3K/Akt-Nrf2-activated antioxidant gene expression and suppressing MAPK-regulated apoptosis in neuronal SH-SY5Y cells

(2021) Mayuko Sugimoto et al.   NEUROTOXICOLOGY

The Antiviral Roles of Hydrogen Sulfide by Blocking the Interaction between SARS-CoV-2 and Its Potential Cell Surface Receptors

(2021) Jing Dai et al.   Oxidative Medicine and Cellular Longevity

Resveratrol and endothelial function: A literature review

(2021) Negin Parsamanesh et al.   PHARMACOLOGICAL RESEARCH

Levamisole Therapy in COVID-19

(2021) Hayder M. Al-kuraishy et al.   VIRAL IMMUNOLOGY

Interplay between nuclear factor erythroid 2-related factor 2 and inflammatory mediators in COVID-19-related liver injury

(2021) Dan-Dan Zhu et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Testosterone in COVID-19: An Adversary Bane or Comrade Boon

(2021) Hayder M. Al-kuraishy et al.   Frontiers in Cellular and Infection Microbiology

Management of COVID-19-induced cytokine storm by Keap1-Nrf2 system: a review

(2021) Ekta Singh et al.   INFLAMMOPHARMACOLOGY

Impact of Sitagliptin in Non-Diabetic Covid-19 Patients

(2021) Hayder M. Al-kuraishy et al.   Current Molecular Pharmacology

Resveratrol as an Adjunctive Therapy for Excessive Oxidative Stress in Aging COVID-19 Patients

(2021) Min-Tser Liao et al.   Antioxidants

The Rise of SARS-CoV-2 Variants and the Role of Convalescent Plasma Therapy for Management of Infections

(2021) Mohamed Moubarak et al.   Life-Basel

Possible Therapeutic Effects of Adjuvant Quercetin Supplementation Against Early-Stage COVID-19 Infection: A Prospective, Randomized, Controlled, and Open-Label Study

(2021) Francesco Di Pierro et al.   International Journal of General Medicine

Arginine vasopressin and pathophysiology of COVID-19: An innovative perspective

(2021) Hayder M. Al-kuraishy et al.   BIOMEDICINE & PHARMACOTHERAPY

The PI3K/Akt/mTOR pathway: A potential pharmacological target in COVID-19

(2021) Maria Sofia Basile et al.   DRUG DISCOVERY TODAY

Lycopene attenuates zearalenone-induced oxidative damage of piglet sertoli cells through the nuclear factor erythroid-2 related factor 2 signaling pathway

(2021) Li Cao et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Niclosamide for Covid-19: bridging the gap

(2021) Hayder M. Al-kuraishy et al.   MOLECULAR BIOLOGY REPORTS

Inhibitory effects of sulforaphane on NLRP3 inflammasome activation

(2021) Cagla Kiser et al.   MOLECULAR IMMUNOLOGY

Effects of β-Blockers on the Sympathetic and Cytokines Storms in Covid-19

(2021) Hayder M. Al-kuraishy et al.   Frontiers in Immunology

Maternal Transmission of SARS-CoV-2: Safety of Breastfeeding in Infants Born to Infected Mothers

(2021) Hayder M. Al-kuraishy et al.   Frontiers in Pediatrics

Acute kidney injury and COVID-19

(2021) Hayder M. Al-kuraishy et al.   The Egyptian Journal of Internal Medicine

Re-epithelialization and immune cell behaviour in an ex vivo human skin model

(2020) Ana Rakita et al.   Scientific Reports

Possible application of H2S-producing compounds in therapy of coronavirus (COVID-19) infection and pneumonia

(2020) Mikhail B. Evgen’ev et al.   CELL STRESS & CHAPERONES

Transcription Factor Nrf2 as a Potential Therapeutic Target for Prevention of Cytokine Storm in COVID-19 Patients

(2020) R. A. Zinovkin et al.   BIOCHEMISTRY-MOSCOW

COVID‐19 in dimethyl fumarate‐treated patients with multiple sclerosis

(2020) Vittorio Mantero et al.   JOURNAL OF NEUROLOGY

Cytokine Storm in COVID-19—Immunopathological Mechanisms, Clinical Considerations, and Therapeutic Approaches: The REPROGRAM Consortium Position Paper

(2020) Sonu Bhaskar et al.   Frontiers in Immunology

Nrf2 Activator PB125® as a Potential Therapeutic Agent against COVID-19

(2020) Joe M. McCord et al.   Antioxidants

Flavonoids Activation of the Transcription Factor Nrf2 as a Hypothesis Approach for the Prevention and Modulation of SARS-CoV-2 Infection Severity

(2020) Patricia Mendonca et al.   Antioxidants

Cytokine storm induced by SARS-CoV-2

(2020) Peipei Song et al.   CLINICA CHIMICA ACTA

COVID-19 medical management including World Health Organization (WHO) suggested management strategies

(2020) Dr. R.B. McFee   DM DISEASE-A-MONTH

Can Activation of NRF2 Be a Strategy against COVID-19?

(2020) Antonio Cuadrado et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Dissecting the Crosstalk between NRF2 Signaling and Metabolic Processes in Cancer

(2020) Janine M. DeBlasi et al.   Cancers

mTOR inhibition in COVID‐19: A commentary and review of efficacy in RNA viruses

(2020) Basil S. Karam et al.   JOURNAL OF MEDICAL VIROLOGY

Aqueous extract of Whitmania pigra Whitman ameliorates ferric chloride-induced venous thrombosis in rats via antioxidation

(2020) Peng Li et al.   JOURNAL OF THROMBOSIS AND THROMBOLYSIS

An Overview of Nrf2 Signaling Pathway and Its Role in Inflammation

(2020) Sarmistha Saha et al.   MOLECULES

Calming the (Cytokine) Storm: Dimethyl Fumarate as a Therapeutic Candidate for COVID-19

(2020) Cara A. Timpani et al.   Pharmaceuticals

Hydrogen gas reduces HMGB1 release in lung tissues of septic mice in an Nrf2/HO-1-dependent pathway

(2019) Yang Yu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Concomitant Nrf2- and ATF4-activation by Carnosic Acid Cooperatively Induces Expression of Cytoprotective Genes

(2019) Junsei Mimura et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Nrf2 as a Potential Mediator of Cardiovascular Risk in Metabolic Diseases

(2019) Rafael M. da Costa et al.   Frontiers in Pharmacology

Curcumin upregulates the Nrf2 system by repressing inflammatory signaling-mediated Keap1 expression in insulin-resistant conditions

(2019) Liwei Ren et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Broccoli or Sulforaphane: Is It the Source or Dose That Matters?

(2019) Yoko Yagishita et al.   MOLECULES

β-Lactoglobulin Heptapeptide Reduces Oxidative Stress in Intestinal Epithelial Cells and Angiotensin II-Induced Vasoconstriction on Mouse Mesenteric Arteries by Induction of Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) Translocation

(2019) Giacomo Pepe et al.   Oxidative Medicine and Cellular Longevity

Single-cell RNA-sequencing of herpes simplex virus 1-infected cells connects NRF2 activation to an antiviral program

(2019) Emanuel Wyler et al.   Nature Communications

Pathogenesis of chronic obstructive pulmonary disease (COPD) induced by cigarette smoke

(2019) Mari Hikichi et al.   Journal of Thoracic Disease

Interaction Energetics and Druggability of the Protein–Protein Interaction between Kelch-like ECH-Associated Protein 1 (KEAP1) and Nuclear Factor Erythroid 2 Like 2 (Nrf2)

(2019) Mengqi Zhong et al.   BIOCHEMISTRY

The pivotal role of nuclear factor erythroid 2-related factor 2 in diabetes-induced endothelial dysfunction

(2019) Amin Karan et al.   PHARMACOLOGICAL RESEARCH

Nrf2 as regulator of innate immunity: A molecular Swiss army knife!

(2018) Maurizio Battino et al.   BIOTECHNOLOGY ADVANCES

Nrf2 protects against acute lung injury and inflammation by modulating TLR4 and Akt signaling

(2018) Jia Yan et al.   FREE RADICAL BIOLOGY AND MEDICINE

The role of Nrf2 transcription factor in viral infection

(2018) Ali Ramezani et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Role of Nrf2 in preventing oxidative stress induced chloride current alteration in human lung cells

(2018) Rita Canella et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Eucommia ulmoides Ameliorates Glucotoxicity by Suppressing Advanced Glycation End-Products in Diabetic Mice Kidney

(2018) Moon Do et al.   Nutrients

Alleviation of Acute Lung Injury in Rats with Sepsis by Resveratrol via the Phosphatidylinositol 3-Kinase/Nuclear Factor-Erythroid 2 Related Factor 2/Heme Oxygenase-1 (PI3K/Nrf2/HO-1) Pathway

(2018) Yu Wang et al.   MEDICAL SCIENCE MONITOR

Protective Role of Nuclear Factor Erythroid 2-Related Factor 2 Against Respiratory Syncytial Virus and Human Metapneumovirus Infections

(2018) Teodora Ivanciuc et al.   Frontiers in Immunology

HYCO-3, a dual CO-releaser/Nrf2 activator, reduces tissue inflammation in mice challenged with lipopolysaccharide

(2018) Roberto Motterlini et al.   Redox Biology

Nrf2, the Master Regulator of Anti-Oxidative Responses

(2017) Sandra Vomund et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Isoliquiritigenin Activates Nuclear Factor Erythroid-2 Related Factor 2 to Suppress the NOD-Like Receptor Protein 3 Inflammasome and Inhibits the NF-κB Pathway in Macrophages and in Acute Lung Injury

(2017) Qinmei Liu et al.   Frontiers in Immunology

Dimethylfumarate Impairs Neutrophil Functions

(2016) Susen Müller et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Dimethyl fumarate attenuates experimental autoimmune neuritis through the nuclear factor erythroid-derived 2-related factor 2/hemoxygenase-1 pathway by altering the balance of M1/M2 macrophages

(2016) Ranran Han et al.   Journal of Neuroinflammation

Multiple regulations of Keap1/Nrf2 system by dietary phytochemicals

(2016) Si Qin et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription

(2016) Eri H. Kobayashi et al.   Nature Communications

Sulforaphane protects against rotenone-induced neurotoxicity in vivo: Involvement of the mTOR, Nrf2 and autophagy pathways

(2016) Qian Zhou et al.   Scientific Reports

The antioxidant function of sestrins is mediated by promotion of autophagic degradation of Keap1 and Nrf2 activation and by inhibition of mTORC1

(2015) Sue Goo Rhee et al.   FREE RADICAL BIOLOGY AND MEDICINE

Activation of Nuclear Factor Erythroid 2-Related Factor 2 Coordinates Dimethylarginine Dimethylaminohydrolase/PPAR- /Endothelial Nitric Oxide Synthase Pathways That Enhance Nitric Oxide Generation in Human Glomerular Endothelial Cells

(2015) Z. Luo et al.   HYPERTENSION

Sappanone A exhibits anti-inflammatory effects via modulation of Nrf2 and NF-κB

(2015) Suhyun Lee et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The role of Nrf2 in oxidative stress-induced endothelial injuries

(2015) B. Chen et al.   JOURNAL OF ENDOCRINOLOGY

Dietary ellagic acid improves oxidant-induced endothelial dysfunction and atherosclerosis: Role of Nrf2 activation

(2014) Yi Ding et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Apurinic/Apyrimidinic Endonuclease/Redox Factor-1 (APE1/Ref-1) Redox Function Negatively Regulates NRF2

(2014) Melissa L. Fishel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nrf2/ARE pathway activation, HO-1 and NQO1 induction by polychlorinated biphenyl quinone is associated with reactive oxygen species and PI3K/AKT signaling

(2013) Lingrui Li et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Targeting the transcription factor Nrf2 to ameliorate oxidative stress and inflammation in chronic kidney disease

(2013) Stacey Ruiz et al.   KIDNEY INTERNATIONAL

Modulation of Nrf2/Keap1 system by Wasabi 6-methylthiohexyl isothiocyanate in ARE-mediatedNQO1expression

(2013) Yoshimi Korenori et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Inhibition of Nuclear Factor Erythroid 2-Related Factor 2 Exacerbates HIV-1 gp120-Induced Oxidative and Inflammatory Response: Role in HIV Associated Neurocognitive Disorder

(2012) Pichili Vijaya Bhaskar Reddy et al.   NEUROCHEMICAL RESEARCH

Sodium Thiosulfate Pharmacokinetics in Hemodialysis Patients and Healthy Volunteers

(2011) S. Farese et al.   Clinical Journal of the American Society of Nephrology

TNF Mediates the Sustained Activation of Nrf2 in Human Monocytes

(2011) S. A. Rushworth et al.   JOURNAL OF IMMUNOLOGY

Keap1-Nrf2 activation in the presence and absence of DJ-1

(2010) Li Gan et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

The Nrf2 System as a Potential Target for the Development of Indirect Antioxidants

(2010) Kyeong-Ah Jung et al.   MOLECULES