Effects of β-Blockers on the Sympathetic and Cytokines Storms in Covid-19

Central and peripheral nervous system complications of COVID-19: a prospective tertiary center cohort with 3-month follow-up

(2021) Vardan Nersesjan et al.   JOURNAL OF NEUROLOGY

PDE4 inhibition as a therapeutic strategy for improvement of pulmonary dysfunctions in Covid-19 and cigarette smoking

(2021) Claire Lugnier et al.   BIOCHEMICAL PHARMACOLOGY

SARS-CoV-2 mediated neuroinflammation and the impact of COVID-19 in neurological disorders

(2021) Narayanappa Amruta et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Immune cartography of macrophage activation syndrome in the COVID-19 era

(2021) Dennis McGonagle et al.   Nature Reviews Rheumatology

Sequential doxycycline and colchicine combination therapy in Covid-19: The salutary effects

(2021) Hayder M. Al-kuraishy et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Oxidative Stress Status in COVID-19 Patients Hospitalized in Intensive Care Unit for Severe Pneumonia. A Pilot Study

(2021) Joël Pincemail et al.   Antioxidants

COVID-19 and Risk of Acute Ischemic Stroke and Acute Lung Injury in Patients With Type II Diabetes Mellitus: The Anti-inflammatory Role of Metformin

(2021) Hayder M. Al-kuraishy et al.   Frontiers in Medicine

Case Report: Hyperbilirubinemia in Gilbert Syndrome Attenuates Covid-19-Induced Metabolic Disturbances

(2021) Hayder M. Al-kuraishy et al.   Frontiers in Cardiovascular Medicine

Role of leukotriene pathway and montelukast in pulmonary and extrapulmonary manifestations of Covid-19: The enigmatic entity

(2021) Hayder M. Al-kuraishy et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Pleiotropic Effects of Tetracyclines in the Management of COVID-19: Emerging Perspectives

(2021) Hayder M. Al-kuraishy et al.   Frontiers in Pharmacology

Immunological Interfaces: The COVID-19 Pandemic and Depression

(2021) Austin Perlmutter   Frontiers in Neurology

The Association Between Alpha-1 Adrenergic Receptor Antagonists and In-Hospital Mortality From COVID-19

(2021) Liam Rose et al.   Frontiers in Medicine

Global Incidence of Neurological Manifestations Among Patients Hospitalized With COVID-19—A Report for the GCS-NeuroCOVID Consortium and the ENERGY Consortium

(2021) Sherry H.-Y. Chou et al.   JAMA Network Open

COVID-19 in Relation to Hyperglycemia and Diabetes Mellitus

(2021) Hayder M. Al-kuraishy et al.   Frontiers in Cardiovascular Medicine

The potential role of neopterin in Covid-19: a new perspective

(2021) Hayder M. Al-kuraishy et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Emerging COVID-19 Neurological Manifestations: Present Outlook and Potential Neurological Challenges in COVID-19 Pandemic

(2021) Saikat Dewanjee et al.   MOLECULAR NEUROBIOLOGY

Levamisole Therapy in COVID-19

(2021) Hayder M. Al-kuraishy et al.   VIRAL IMMUNOLOGY

Impact of Sitagliptin in Non-Diabetic Covid-19 Patients

(2021) Hayder M. Al-kuraishy et al.   Current Molecular Pharmacology

Paroxysmal Sympathetic Hyperactivity in Moderate-to-Severe Traumatic Brain Injury and the Role of Beta-Blockers: A Scoping Review

(2021) Stéphane Nguembu et al.   Emergency Medicine International

The Rise of SARS-CoV-2 Variants and the Role of Convalescent Plasma Therapy for Management of Infections

(2021) Mohamed Moubarak et al.   Life-Basel

Serial markers of coagulation and inflammation and the occurrence of clinical pulmonary thromboembolism in mechanically ventilated patients with SARS-CoV-2 infection; the prospective Maastricht intensive care COVID cohort

(2021) Mark M. G. Mulder et al.   Thrombosis Journal

Arginine vasopressin and pathophysiology of COVID-19: An innovative perspective

(2021) Hayder M. Al-kuraishy et al.   BIOMEDICINE & PHARMACOTHERAPY

A rational roadmap for SARS‐CoV‐2/COVID‐19 pharmacotherapeutic research and development. IUPHAR Review 29

(2020) S.P.H. Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

COVID-19 and Multiorgan Response

(2020) Sevim Zaim et al.   CURRENT PROBLEMS IN CARDIOLOGY

Preventing cytokine storm syndrome in COVID-19 using α-1 adrenergic receptor antagonists

(2020) Maximilian F. Konig et al.   JOURNAL OF CLINICAL INVESTIGATION

Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy

(2020) Ning Tang et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Involvement of the Nervous System in SARS-CoV-2 Infection

(2020) Hao Li et al.   NEUROTOXICITY RESEARCH

Vascular Endothelial Growth Factor (VEGF) as a Vital Target for Brain Inflammation during the COVID-19 Outbreak

(2020) Xi-Xi Yin et al.   ACS Chemical Neuroscience

Distribution of ACE2, CD147, CD26 and other SARS‐CoV‐2 associated molecules in tissues and immune cells in health and in asthma, COPD, obesity, hypertension, and COVID‐19 risk factors

(2020) U. Radzikowska et al.   ALLERGY

The potential role of the Carotid Body in COVID-19

(2020) Andrea Porzionato et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Sympathetic activation: a potential link between comorbidities and COVID‐19

(2020) Andrea Porzionato et al.   FEBS Journal

Inflammation suppression by dexamethasone via inhibition of CD147-mediated NF-κB pathway in collagen-induced arthritis rats

(2020) Qishan Wang et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

COVID-19, Mast Cells, Cytokine Storm, Psychological Stress, and Neuroinflammation

(2020) Duraisamy Kempuraj et al.   NEUROSCIENTIST

Rugosic acid A, derived from Rosa rugosa Thunb., is novel inhibitory agent for NF‐κB and IL ‐6/ STAT3 axis in acute lung injury model

(2020) Kang‐Hoon Kim et al.   PHYTOTHERAPY RESEARCH

Targeting the NLRP3 Inflammasome in Severe COVID-19

(2020) Tracey L. Freeman et al.   Frontiers in Immunology

Neutrophils and Neutrophil Extracellular Traps Drive Necroinflammation in COVID-19

(2020) Bhawna Tomar et al.   Cells

Intensive care of traumatic brain injury and aneurysmal subarachnoid hemorrhage in Helsinki during the Covid-19 pandemic

(2020) Teemu Luostarinen et al.   ACTA NEUROCHIRURGICA

Beta‐Adrenergic Blockers as a Potential Treatment for COVID‐19 Patients

(2020) Natesan Vasanthakumar   BIOESSAYS

β2-AR blockade potentiates MEK1/2 inhibitor effect on HNSCC by regulating the Nrf2-mediated defense mechanism

(2020) Luigi Mele et al.   Cell Death & Disease

Potential Role of Autonomic Dysfunction in Covid-19 Morbidity and Mortality

(2020) Rodrigo Del Rio et al.   Frontiers in Physiology

Can Beta-2-Adrenergic Pathway Be a New Target to Combat SARS-CoV-2 Hyperinflammatory Syndrome?—Lessons Learned From Cancer

(2020) Antonio Barbieri et al.   Frontiers in Immunology

Locus Coeruleus Modulates Neuroinflammation in Parkinsonism and Dementia

(2020) Filippo Sean Giorgi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Blood Biomarkers for Detection of Brain Injury in COVID-19 Patients

(2020) Steven T. DeKosky et al.   JOURNAL OF NEUROTRAUMA

Gamma-oryzanol as a potential modulator of oxidative stress and inflammation via PPAR-y in adipose tissue: a hypothetical therapeutic for cytokine storm in COVID-19?

(2020) Fabiane Valentini Francisqueti-Ferron et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Beta-adrenergic receptor antagonism is proinflammatory and exacerbates neuroinflammation in a mouse model of Alzheimer's Disease

(2020) Andrew K. Evans et al.   NEUROBIOLOGY OF DISEASE

Cytokine Storm

(2020) David C. Fajgenbaum et al.   NEW ENGLAND JOURNAL OF MEDICINE

Catecholamine physiology and its implications in patients with COVID-19

(2020) Sriram Gubbi et al.   Lancet Diabetes & Endocrinology

Angiotensin II and vascular damage in hypertension: Role of oxidative stress and sympathetic activation

(2019) Stefano Masi et al.   VASCULAR PHARMACOLOGY

β blockers to prevent decompensation of cirrhosis in patients with clinically significant portal hypertension (PREDESCI): a randomised, double-blind, placebo-controlled, multicentre trial

(2019) Càndid Villanueva et al.   LANCET

Nebivolol Improves Obesity-Induced Vascular Remodeling by Suppressing NLRP3 Activation

(2019) Jing Gao et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Augmented β2-adrenergic signaling dampens the neuroinflammatory response following ischemic stroke and increases stroke size

(2019) Kendra J. Lechtenberg et al.   Journal of Neuroinflammation

Capillary leak syndrome: a cytokine and catecholamine storm?

(2019) Eric Siddall et al.   KIDNEY INTERNATIONAL

Catecholamines contribute to the neovascularization of lung cancer via tumor-associated macrophages

(2019) Yun Xia et al.   BRAIN BEHAVIOR AND IMMUNITY

Shaping the future of an ultra-rare disease

(2019) Cormac McCarthy et al.   CURRENT OPINION IN PULMONARY MEDICINE

Effect of β-blockers on triggering of symptomatic atrial fibrillation by anger or stress

(2019) Rachel Lampert et al.   HEART RHYTHM

Inhibition of CD147 Attenuates Stroke-Associated Pneumonia Through Modulating Lung Immune Response in Mice

(2019) Rong Jin et al.   Frontiers in Neurology

ACE2 and ADAM17 Interaction Regulates the Activity of Presympathetic Neurons

(2019) Snigdha Mukerjee et al.   HYPERTENSION

Obesity Affects β2 Adrenergic Regulation of the Inflammatory Profile and Phenotype of Circulating Monocytes from Exercised Animals

(2019) Isabel Gálvez et al.   Nutrients

Neuroinflammation in heart failure: new insights for an old disease

(2019) Hugo S. Díaz et al.   JOURNAL OF PHYSIOLOGY-LONDON

Neuroinflammation and sympathetic overactivity: Mechanisms and implications in hypertension

(2018) Dhanush Haspula et al.   AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL

Inhibition of the cyclophilin A–CD147 interaction attenuates right ventricular injury and dysfunction after acute pulmonary embolism in rats

(2018) Guangdong Lu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adrenergic and glucocorticoid receptor antagonists reduce ozone-induced lung injury and inflammation

(2018) Andres R. Henriquez et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Disruption of a self-amplifying catecholamine loop reduces cytokine release syndrome

(2018) Verena Staedtke et al.   NATURE

Adrenaline fuels a cytokine storm during immunotherapy

(2018) Stanley R. RIddell   NATURE

Bidirectional Role of β2-Adrenergic Receptor in Autoimmune Diseases

(2018) Li Wu et al.   Frontiers in Pharmacology

Beta-blockers for heart failure with reduced, mid-range, and preserved ejection fraction: an individual patient-level analysis of double-blind randomized trials

(2017) John G F Cleland et al.   EUROPEAN HEART JOURNAL

Lethal concentration of perfluoroisobutylene induces acute lung injury in mice mediated via cytokine storm, oxidative stress and apoptosis

(2017) Yingjie Zhang et al.   INHALATION TOXICOLOGY

Propranolol treatment prevents chronic central sensitization induced by repeated dural stimulation

(2017) Nelly Boyer et al.   PAIN

Inhibition of CD147 (Cluster of Differentiation 147) Ameliorates Acute Ischemic Stroke in Mice by Reducing Thromboinflammation

(2017) Rong Jin et al.   STROKE

Novel Biomarkers for Cardiac Hypertrophy, Fibrosis and Failure: Cyclophilin A and Basigin—Clinical Application of Basic Research-

(2016) Kimio Satoh et al.   JOURNAL OF CARDIAC FAILURE

Treatment with non-selective beta blockers is associated with reduced severity of systemic inflammation and improved survival of patients with acute-on-chronic liver failure

(2016) Rajeshwar P. Mookerjee et al.   JOURNAL OF HEPATOLOGY

Propranolol Attenuates Surgical Stress–Induced Elevation of the Regulatory T Cell Response in Patients Undergoing Radical Mastectomy

(2016) Lei Zhou et al.   JOURNAL OF IMMUNOLOGY

Propranolol induced G0/G1/S phase arrest and apoptosis in melanoma cells via AKT/MAPK pathway

(2016) Chengfang Zhou et al.   Oncotarget

Reply: β2-Agonists and Acute Respiratory Distress Syndrome

(2014) G. R. Scott Budinger et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Cross-talk between the inflammatory response, sympathetic activation and pulmonary infection in the ischemic stroke

(2014) Pawel J Winklewski et al.   Journal of Neuroinflammation

Uptitration of Renin-Angiotensin System Blocker and Beta-Blocker Therapy in Patients Hospitalized for Heart Failure With Reduced Versus Preserved Left Ventricular Ejection Fractions

(2013) Frederik H. Verbrugge et al.   AMERICAN JOURNAL OF CARDIOLOGY

Treatment of Acute Lung Injury: Current and Emerging Pharmacological Therapies

(2013) Rob Sweeney et al.   SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE

CD147 induces angiogenesis through a vascular endothelial growth factor and hypoxia-inducible transcription factor 1α-mediated pathway in rheumatoid arthritis

(2011) Cong-hua Wang et al.   ARTHRITIS AND RHEUMATISM

β-Adrenergic receptors (β-AR) regulate VEGF and IL-6 production by divergent pathways in high β-AR-expressing breast cancer cell lines

(2011) Kelley S. Madden et al.   BREAST CANCER RESEARCH AND TREATMENT

Role of endothelial nitric oxide synthase (eNOS) in chronic stress-promoted tumour growth

(2011) Antonio Barbieri et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Paroxysmal Sympathetic Hyperactivity (Sympathetic Storm) in a Patient with Permanent Vegetative State

(2011) Emily R. Levy et al.   JOURNAL OF PALLIATIVE MEDICINE

The β2-subtype of adrenoceptors mediates inhibition of pro-fibrotic events in human lung fibroblasts

(2011) F. Lamyel et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Regulation of tonic GABA inhibitory function, presympathetic neuronal activity and sympathetic outflow from the paraventricular nucleus by astroglial GABA transporters

(2009) Jin Bong Park et al.   JOURNAL OF PHYSIOLOGY-LONDON

Type I and Type II Interferons Inhibit the Translation of Murine Norovirus Proteins

(2009) H. Changotra et al.   JOURNAL OF VIROLOGY

Upregulation of Phagocyte-Derived Catecholamines Augments the Acute Inflammatory Response

(2009) Michael A. Flierl et al.   PLoS One

Alveolar Epithelial β2-Adrenergic Receptors

(2007) Gökhan M. Mutlu et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY