Roxadustat for SARS-CoV-2 Infection: Old Signaling Raised New Hopes

Innate immunological pathways in COVID-19 pathogenesis

(2022) Søren R. Paludan et al.   Science Immunology

Melatonin increased hypoxia‐inducible factor ( HIF ) by inhibiting prolyl hydroxylase: A hypothesis for treating anaemia, ischaemia, and covid‐19

(2022) Mohammad Hossein Hosseinzadeh et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Roxadustat for the treatment of anemia in chronic kidney disease patients not on dialysis: a phase 3, randomized, double-blind, placebo-controlled study (ALPS)

(2021) Evgeny Shutov et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

HIF Prolyl Hydroxylase Inhibitors for COVID-19 Treatment: Pros and Cons

(2021) Andrey A. Poloznikov et al.   Frontiers in Pharmacology

Hypoxic and pharmacological activation of HIF inhibits SARS-CoV-2 infection of lung epithelial cells

(2021) Peter A.C. Wing et al.   Cell Reports

COVID-19 in Relation to Hyperglycemia and Diabetes Mellitus

(2021) Hayder M. Al-kuraishy et al.   Frontiers in Cardiovascular Medicine

Population pharmacokinetics of roxadustat in Japanese dialysis‐dependent chronic kidney disease patients with anaemia

(2021) Akitsugu Takada et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

The potential role of neopterin in Covid-19: a new perspective

(2021) Hayder M. Al-kuraishy et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

CD209L/L-SIGN and CD209/DC-SIGN Act as Receptors for SARS-CoV-2

(2021) Razie Amraei et al.   ACS Central Science

Roxadustat Does Not Affect Platelet Production, Activation, and Thrombosis Formation

(2021) Jiaxin Zhao et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors for Anemia in CKD

(2021) Patrick Parfrey   NEW ENGLAND JOURNAL OF MEDICINE

Hypoxia-inducible factor (HIF)-prolyl hydroxylase 3 (PHD3) maintains high HIF2A mRNA levels in clear cell renal cell carcinoma

(2019) Petra Miikkulainen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Roxadustat in the treatment of anaemia in chronic kidney disease

(2017) Lucia Del Vecchio et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS