Dimethyl fumarate attenuates experimental autoimmune neuritis through the nuclear factor erythroid-derived 2-related factor 2/hemoxygenase-1 pathway by altering the balance of M1/M2 macrophages

An overview of the molecular mechanisms and novel roles of Nrf2 in neurodegenerative disorders

(2015) Yang Yang et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Dimethyl Fumarate Ameliorates Lewis Rat Experimental Autoimmune Neuritis and Mediates Axonal Protection

(2015) Kalliopi Pitarokoili et al.   PLoS One

Dimethyl Fumarate Protects Brain From Damage Produced by Intracerebral Hemorrhage by Mechanism Involving Nrf2

(2015) Xiurong Zhao et al.   STROKE

Dimethyl fumarate in the treatment of relapsing–remitting multiple sclerosis: an overview

(2015) Roberto Bomprezzi   Therapeutic Advances in Neurological Disorders

Heme oxygenase-1 and anti-inflammatory M2 macrophages

(2014) Yuji Naito et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Hydroxycarboxylic acid receptor 2 mediates dimethyl fumarate’s protective effect in EAE

(2014) Hui Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

The Transcription Factor Nrf2 Is a Therapeutic Target against Brain Inflammation

(2014) N. G. Innamorato et al.   JOURNAL OF IMMUNOLOGY

Chrysin attenuates experimental autoimmune neuritis by suppressing immuno-inflammatory responses

(2014) J. Xiao et al.   NEUROSCIENCE

Dimethyl Fumarate Protects Pancreatic Islet Cells and Non-Endocrine Tissue in L-Arginine-Induced Chronic Pancreatitis

(2014) Lourdes Robles et al.   PLoS One

Th1/Th2/Th17/Treg cytokines in Guillain–Barré syndrome and experimental autoimmune neuritis

(2013) Hong-Liang Zhang et al.   CYTOKINE & GROWTH FACTOR REVIEWS

The fumaric acid ester BG-12: a new option in MS therapy

(2013) De-Hyung Lee et al.   Expert Review of Neurotherapeutics

Glatiramer acetate ameliorates experimental autoimmune neuritis

(2013) Cun-Jin Zhang et al.   IMMUNOLOGY AND CELL BIOLOGY

Macrophage biology in development, homeostasis and disease

(2013) Thomas A. Wynn et al.   NATURE

Mechanisms of Oxidative Damage in Multiple Sclerosis and Neurodegenerative Diseases: Therapeutic Modulation via Fumaric Acid Esters

(2012) De-Hyung Lee et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Macrophage plasticity and polarization: in vivo veritas

(2012) Antonio Sica et al.   JOURNAL OF CLINICAL INVESTIGATION

Macrophage plasticity and polarization in tissue repair and remodelling

(2012) Alberto Mantovani et al.   JOURNAL OF PATHOLOGY

Guillain–Barré Syndrome

(2012) Nobuhiro Yuki et al.   NEW ENGLAND JOURNAL OF MEDICINE

Placebo-Controlled Phase 3 Study of Oral BG-12 or Glatiramer in Multiple Sclerosis

(2012) Robert J. Fox et al.   NEW ENGLAND JOURNAL OF MEDICINE

Attenuated EAN in TNF-α Deficient Mice Is Associated with an Altered Balance of M1/M2 Macrophages

(2012) Hong-Liang Zhang et al.   PLoS One

Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway

(2011) Ralf A. Linker et al.   BRAIN

Molecular Mechanism for Adiponectin-dependent M2 Macrophage Polarization

(2011) Palash Mandal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fumarates improve psoriasis and multiple sclerosis by inducing type II dendritic cells

(2011) Kamran Ghoreschi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Signaling to heme oxygenase-1 and its anti-inflammatory therapeutic potential

(2010) Ananta Paine et al.   BIOCHEMICAL PHARMACOLOGY

Dimethyl fumarate for multiple sclerosis

(2010) Athina Papadopoulou et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

The Nrf2 System as a Potential Target for the Development of Indirect Antioxidants

(2010) Kyeong-Ah Jung et al.   MOLECULES

Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm

(2010) Subhra K Biswas et al.   NATURE IMMUNOLOGY

Heme Oxygenase-1/Carbon Monoxide

(2009) Stefan W. Ryter et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Compound A, a Plant Origin Ligand of Glucocorticoid Receptors, Increases Regulatory T Cells and M2 Macrophages to Attenuate Experimental Autoimmune Neuritis with Reduced Side Effects

(2009) Z. Zhang et al.   JOURNAL OF IMMUNOLOGY

Beneficial Effects of Dimethyl Fumarate on Experimental Autoimmune Myocarditis

(2008) Marina Milenković et al.   ARCHIVES OF MEDICAL RESEARCH

Efficacy and safety of oral fumarate in patients with relapsing-remitting multiple sclerosis: a multicentre, randomised, double-blind, placebo-controlled phase IIb study

(2008) Ludwig Kappos et al.   LANCET