- Home
- Publications
- Publication Search
- Publication Details
Title
Phosphodiesterase inhibitors in psychiatric disorders
Authors
Keywords
-
Journal
PSYCHOPHARMACOLOGY
Volume 240, Issue 6, Pages 1201-1219
Publisher
Springer Science and Business Media LLC
Online
2023-04-15
DOI
10.1007/s00213-023-06361-3
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Cilostazol as an adjunctive treatment in major depressive disorder: a pilot randomized, double-blind, and placebo-controlled clinical trial
- (2022) Aida Khadivi et al. PSYCHOPHARMACOLOGY
- Pharmaceutical management of sexual dysfunction in men on antidepressant therapy
- (2022) Ahmed M. Bakr et al. EXPERT OPINION ON PHARMACOTHERAPY
- Inhibition of Phosphodiesterase 2 Ameliorates Post-Traumatic Stress–Induced Alcohol Intake Disorder by Regulating cAMP/cGMP Signaling
- (2022) Xiaoyu Pan et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- Allopurinol, dipyridamole and calcium channel blockers in the treatment of bipolar disorder – A nationwide cohort study
- (2022) Jonne Lintunen et al. JOURNAL OF AFFECTIVE DISORDERS
- Emerging Potential of the Phosphodiesterase (PDE) Inhibitor Ibudilast for Neurodegenerative Diseases: An Update on Preclinical and Clinical Evidence
- (2022) Efthalia Angelopoulou et al. MOLECULES
- Recent developments of phosphodiesterase inhibitors: Clinical trials, emerging indications and novel molecules
- (2022) Andrey D. Bondarev et al. Frontiers in Pharmacology
- Role of phosphodiesterases in the pathophysiology of neurodevelopmental disorders
- (2021) Sébastien Delhaye et al. MOLECULAR PSYCHIATRY
- Challenges of Psychiatry Drug Development and the Role of Human Pharmacology Models in Early Development—A Drug Developer's Perspective
- (2021) Tong Zhu Frontiers in Psychiatry
- Phosphodiesterase type 1 inhibition alters medial prefrontal cortical activity during goal-driven behaviour and partially reverses neurophysiological deficits in the rat phencyclidine model of schizophrenia
- (2021) Jessica Hayes et al. NEUROPHARMACOLOGY
- Genome-wide analysis suggests the importance of vascular processes and neuroinflammation in late-life antidepressant response
- (2021) Victoria S. Marshe et al. Translational Psychiatry
- Efficacy and safety of pentoxifylline combination therapy in major depressive disorder: a randomized, double-blind, placebo-controlled clinical trial
- (2021) Mostafa Farajollahi-Moghadam et al. INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY
- Challenges on Cyclic Nucleotide Phosphodiesterases Imaging with Positron Emission Tomography: Novel Radioligands and (Pre-)Clinical Insights since 2016
- (2021) Susann Schröder et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Preliminary evidence for the phosphodiesterase type-4 inhibitor, roflumilast, in ameliorating cognitive flexibility deficits in patients with schizophrenia
- (2021) Nicholas R Livingston et al. JOURNAL OF PSYCHOPHARMACOLOGY
- Double‐blind, randomized, placebo‐controlled pilot study of the phosphodiesterase‐3 inhibitor cilostazol as an adjunctive to antidepressants in patients with major depressive disorder
- (2021) Mahmoud S. Abdallah et al. CNS Neuroscience & Therapeutics
- Pentoxifylline for treatment of major depression after percutaneous coronary intervention or coronary artery bypass grafting: A randomized, double-blind, placebo-controlled trial
- (2021) Seyyede-Ozra Yasrebi et al. JOURNAL OF PSYCHOSOMATIC RESEARCH
- Psychological Distress in Erectile Dysfunction: The Moderating Role of Attachment
- (2021) Francesc Maestre-Lorén et al. Sexual Medicine
- Therapeutic Potential of Phosphodiesterase Inhibitors against Neurodegeneration: The Perspective of the Medicinal Chemist
- (2020) Giovanni Ribaudo et al. ACS Chemical Neuroscience
- The decline in sexual function, psychological disorders (anxiety and depression) and life satisfaction in older men: A cross‐sectional study in a hospital‐based population
- (2020) Yi Lu et al. ANDROLOGIA
- The Role of BDNF on Neural Plasticity in Depression
- (2020) Tao Yang et al. Frontiers in Cellular Neuroscience
- Dominant-Negative Attenuation of cAMP-Selective Phosphodiesterase PDE4D Action Affects Learning and Behavior
- (2020) Graeme B. Bolger et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Persistence of the extinction of fear memory requires late-phase cAMP/PKA signaling in the infralimbic cortex
- (2020) Jeferson Machado Batista Sohn et al. NEUROBIOLOGY OF LEARNING AND MEMORY
- The effects of roflumilast, a phosphodiesterase type-4 inhibitor, on EEG biomarkers in schizophrenia: A randomised controlled trial
- (2020) James Gilleen et al. JOURNAL OF PSYCHOPHARMACOLOGY
- Tadalafil versus linaclotide in gastrointestinal dysfunction and depressive behavior in constipation–predominant irritable bowel syndrome
- (2020) Amina Ahmed Sedky et al. LIFE SCIENCES
- Phosphodiesterase-4 enzyme as a therapeutic target in neurological disorders
- (2020) Abid Bhat et al. PHARMACOLOGICAL RESEARCH
- Antipsychotic-like effects of a novel phosphodiesterase 10A inhibitor MT-3014 in rats
- (2020) Misae Takakuwa et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- Phosphodiesterase-2 inhibitor reverses post-traumatic stress induced fear memory deficits and behavioral changes via cAMP/cGMP pathway
- (2020) Ling Chen et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Inhibition of phosphodiesterase-4 suppresses HMGB1/RAGE signaling pathway and NLRP3 inflammasome activation in mice exposed to chronic unpredictable mild stress
- (2020) Jinfeng Xie et al. BRAIN BEHAVIOR AND IMMUNITY
- Schizophrenia, Dopamine and the Striatum: From Biology to Symptoms
- (2019) Robert A. McCutcheon et al. TRENDS IN NEUROSCIENCES
- Reduced phosphodiesterase-2 activity in the amygdala results in anxiolytic-like effects on behavior in mice
- (2019) Ling Chen et al. JOURNAL OF PSYCHOPHARMACOLOGY
- Target Engagement of a Phosphodiesterase 2 (PDE2) Inhibitor Affecting Long-Term Memory in the Rat
- (2019) Guibao Gu et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- The antidepressant- and anxiolytic-like effects of resveratrol: Involvement of phosphodiesterase-4D inhibition
- (2019) Xia Zhu et al. NEUROPHARMACOLOGY
- Fear renewal activates cyclic adenosine monophosphate signaling in the dentate gyrus
- (2019) Yan-Wei Shi et al. Brain and Behavior
- Molecular targets for the interactive effect of etazolate during post-traumatic stress disorder: Role of oxidative stress, BDNF and histones
- (2019) Karem H. Alzoubi et al. BEHAVIOURAL BRAIN RESEARCH
- Impaired Hippocampus-Dependent Associative Learning as a Mechanism Underlying PTSD: A Meta-Analysis
- (2019) Hilary K. Lambert et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- Association study of the PDE4D gene and obsessive-compulsive disorder in a Chinese Han population
- (2019) Xing Huang et al. PSYCHIATRIC GENETICS
- Understanding PDE4's function in Alzheimer's disease; a target for novel therapeutic approaches
- (2019) Amy J. Tibbo et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Balanced activation of striatal output pathways by faster off-rate PDE10A inhibitors elicits not only antipsychotic-like effects but also procognitive effects in rodents
- (2019) Akina Harada et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- A Novel Phosphodiesterase 1 Inhibitor DSR-141562 Exhibits Efficacies in Animal Models for Positive, Negative, and Cognitive Symptoms Associated with Schizophrenia
- (2019) Takeshi Enomoto et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Antipsychotic-like effects of a novel phosphodiesterase 10A inhibitor T-251 in rodents
- (2019) Misae Takakuwa et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- Pentoxifylline prevents post-traumatic stress disorder induced memory impairment
- (2018) Karem H. Alzoubi et al. BRAIN RESEARCH BULLETIN
- A novel PDE9 inhibitor WYQ-C36D ameliorates corticosterone-induced neurotoxicity and depression-like behaviors by cGMP-CREB-related signaling
- (2018) Xian-Feng Huang et al. CNS Neuroscience & Therapeutics
- The neuroprotective and antidepressant-like effects of Hcyb1, a novel selective PDE2 inhibitor
- (2018) Li Liu et al. CNS Neuroscience & Therapeutics
- Inhibition of Phosphodiesterase 4 by FCPR03 Alleviates Lipopolysaccharide-Induced Depressive-Like Behaviors in Mice: Involvement of p38 and JNK Signaling Pathways
- (2018) Hui Yu et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Single-Prolonged Stress: A Review of Two Decades of Progress in a Rodent Model of Post-traumatic Stress Disorder
- (2018) Michael J. Lisieski et al. Frontiers in Psychiatry
- Inhibition of phosphodiesterase 2 reverses gp91phox oxidase-mediated depression- and anxiety-like behavior
- (2018) Xianfeng Huang et al. NEUROPHARMACOLOGY
- The Phosphodiesterase Inhibitor Pentoxifylline as a Novel Adjunct to Antidepressants in Major Depressive Disorder Patients: A Proof-of-Concept, Randomized, Double-Blind, Placebo-Controlled Trial
- (2018) Sahar Mohamed El-Haggar et al. PSYCHOTHERAPY AND PSYCHOSOMATICS
- cAMP Response Element-Binding Protein (CREB): A Possible Signaling Molecule Link in the Pathophysiology of Schizophrenia
- (2018) Haitao Wang et al. Frontiers in Molecular Neuroscience
- Synaptic Plasticity in PTSD and associated Comorbidities: The Function and Mechanism for Diagnostics and Therapy
- (2018) Mei He et al. CURRENT PHARMACEUTICAL DESIGN
- Inhibition of Phosphodiesterase 4 by FCPR03 Alleviates Chronic Unpredictable Mild Stress-Induced Depressive-Like Behaviors and Prevents Dendritic Spine Loss in Mice Hippocampi
- (2018) Hui Yu et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- An experimental medicine study of the phosphodiesterase-4 inhibitor, roflumilast, on working memory-related brain activity and episodic memory in schizophrenia patients
- (2018) James Gilleen et al. PSYCHOPHARMACOLOGY
- Phosphodiesterase-4 Inhibitors for the Treatment of Inflammatory Diseases
- (2018) Heng Li et al. Frontiers in Pharmacology
- FCPR16, a novel phosphodiesterase 4 inhibitor, produces an antidepressant-like effect in mice exposed to chronic unpredictable mild stress
- (2018) Qiuping Zhong et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Cilostazol adjunctive therapy in treatment of negative symptoms in chronic schizophrenia: Randomized, double-blind, placebo-controlled study
- (2017) Farzin Rezaei et al. HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL
- Chronic obstructive pulmonary disease
- (2017) Klaus F Rabe et al. LANCET
- Attenuation of ethanol abstinence-induced anxiety- and depressive-like behavior by the phosphodiesterase-4 inhibitor rolipram in rodents
- (2017) Mei-Fang Gong et al. PSYCHOPHARMACOLOGY
- Genetic compensation: A phenomenon in search of mechanisms
- (2017) Mohamed A. El-Brolosy et al. PLoS Genetics
- Comparison of the Pharmacological Profiles of Selective PDE4B and PDE4D Inhibitors in the Central Nervous System
- (2017) Chong Zhang et al. Scientific Reports
- The phosphodiesterase type 2 inhibitor BAY 60-7550 reverses functional impairments induced by brain ischemia by decreasing hippocampal neurodegeneration and enhancing hippocampal neuronal plasticity
- (2016) Ligia Mendes Soares et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- The microRNA network is altered in anterior cingulate cortex of patients with unipolar and bipolar depression
- (2016) Joshua A. Azevedo et al. JOURNAL OF PSYCHIATRIC RESEARCH
- PDE11A negatively regulates lithium responsivity
- (2016) G Pathak et al. MOLECULAR PSYCHIATRY
- Purification and Characterization of Progenitor and Mature Human Astrocytes Reveals Transcriptional and Functional Differences with Mouse
- (2016) Ye Zhang et al. NEURON
- TAK-063, a PDE10A Inhibitor with Balanced Activation of Direct and Indirect Pathways, Provides Potent Antipsychotic-Like Effects in Multiple Paradigms
- (2016) Kazunori Suzuki et al. NEUROPSYCHOPHARMACOLOGY
- Rolipram improves cognition, reduces anxiety- and despair-like behaviors and impacts hippocampal neuroplasticity after transient global cerebral ischemia
- (2016) Lígia Mendes Soares et al. NEUROSCIENCE
- The centrality of fear extinction in linking risk factors to PTSD: A narrative review
- (2016) Daniel V. Zuj et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- Behavioral and qEEG effects of the PDE10A inhibitor THPP-1 in a novel rhesus model of antipsychotic activity
- (2016) Joshua D. Vardigan et al. PSYCHOPHARMACOLOGY
- Characterisation of Lu AF33241: A novel, brain-penetrant, dual inhibitor of phosphodiesterase (PDE) 2A and PDE10A
- (2015) John P. Redrobe et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Lipoic acid and pentoxifylline mitigate nandrolone decanoate-induced neurobehavioral perturbations in rats via re-balance of brain neurotransmitters, up-regulation of Nrf2/HO-1 pathway, and down-regulation of TNFR1 expression
- (2015) Maha A.E. Ahmed et al. HORMONES AND BEHAVIOR
- Specific Inhibition of Phosphodiesterase-4B Results in Anxiolysis and Facilitates Memory Acquisition
- (2015) Alexander McGirr et al. NEUROPSYCHOPHARMACOLOGY
- Anti-depressant effects of phosphodiesterase 3 inhibitor cilostazol in chronic mild stress-treated mice after ischemic stroke
- (2015) Yu Ri Kim et al. PSYCHOPHARMACOLOGY
- Protective effects of phosphodiesterase 2 inhibitor on depression- and anxiety-like behaviors: Involvement of antioxidant and anti-apoptotic mechanisms
- (2014) Lianshu Ding et al. BEHAVIOURAL BRAIN RESEARCH
- An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex
- (2014) Y. Zhang et al. JOURNAL OF NEUROSCIENCE
- Antidepressant-like effects of the phosphodiesterase-4 inhibitor etazolate and phosphodiesterase-5 inhibitor sildenafil via cyclic AMP or cyclic GMP signaling in mice
- (2014) Chuang Wang et al. METABOLIC BRAIN DISEASE
- Improved Long-Term Memory via Enhancing cGMP-PKG Signaling Requires cAMP-PKA Signaling
- (2014) Eva Bollen et al. NEUROPSYCHOPHARMACOLOGY
- Etazolate abrogates the lipopolysaccharide (LPS)-induced downregulation of the cAMP/pCREB/BDNF signaling, neuroinflammatory response and depressive-like behavior in mice
- (2014) J. Guo et al. NEUROSCIENCE
- Cilostazol improves hippocampus-dependent long-term memory in mice
- (2014) Shuichi Yanai et al. PSYCHOPHARMACOLOGY
- In vitro and in vivo characterisation of Lu AF64280, a novel, brain penetrant phosphodiesterase (PDE) 2A inhibitor: potential relevance to cognitive deficits in schizophrenia
- (2014) John P. Redrobe et al. PSYCHOPHARMACOLOGY
- A phosphodiesterase 4-controlled switch between memory extinction and strengthening in the hippocampus
- (2014) Rafael Roesler et al. Frontiers in Behavioral Neuroscience
- Genetic Deletion and Pharmacological Inhibition of Phosphodiesterase 10A Protects Mice From Diet-Induced Obesity and Insulin Resistance
- (2013) A. R. Nawrocki et al. DIABETES
- Comparative Effectiveness and Safety of Oral Phosphodiesterase Type 5 Inhibitors for Erectile Dysfunction: A Systematic Review and Network Meta-analysis
- (2013) JinQiu Yuan et al. EUROPEAN UROLOGY
- Effects of daily low-dose treatment with phosphodiesterase type 5 inhibitor on cognition, depression, somatization and erectile function in patients with erectile dysfunction: a double-blind, placebo-controlled study
- (2013) Y S Shim et al. INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH
- From Pavlov to PTSD: The extinction of conditioned fear in rodents, humans, and anxiety disorders
- (2013) Michael B. VanElzakker et al. NEUROBIOLOGY OF LEARNING AND MEMORY
- Etazolate, a phosphodiesterase 4 inhibitor reverses chronic unpredictable mild stress-induced depression-like behavior and brain oxidative damage
- (2013) Ankur Jindal et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- Definition and description of schizophrenia in the DSM-5
- (2013) Rajiv Tandon et al. SCHIZOPHRENIA RESEARCH
- Resting Amygdala and Medial Prefrontal Metabolism Predicts Functional Activation of the Fear Extinction Circuit
- (2012) Clas Linnman et al. AMERICAN JOURNAL OF PSYCHIATRY
- Antidepressant-like effect of etazolate, a cyclic nucleotide phosphodiesterase 4 inhibitor—an approach using rodent behavioral antidepressant tests battery
- (2012) Ankur Jindal et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- A new model ofPde4ddeficiency: genetic knock-down of PDE4D enzyme in rats produces an antidepressant phenotype without spatial cognitive effects
- (2012) T. L. Schaefer et al. GENES BRAIN AND BEHAVIOR
- Does Current Scientific and Clinical Evidence Support the Use of Phosphodiesterase Type 5 Inhibitors for the Treatment of Premature Ejaculation? A Systematic Review and Meta‐analysis
- (2012) Anastasios D. Asimakopoulos et al. Journal of Sexual Medicine
- Bidirectional Association Between Depression and Sexual Dysfunction: A Systematic Review and Meta-Analysis
- (2012) Evan Atlantis et al. Journal of Sexual Medicine
- Chronic treatment with the phosphodiesterase type 5 inhibitors sildenafil and tadalafil display anxiolytic effects in Flinders Sensitive Line rats
- (2012) Nico Liebenberg et al. METABOLIC BRAIN DISEASE
- Dual inhibitor of PDE7 and GSK-3 – VP1.15 acts as antipsychotic and cognitive enhancer in C57BL/6J mice
- (2012) Tatiana V. Lipina et al. NEUROPHARMACOLOGY
- The molecular biology of memory: cAMP, PKA, CRE, CREB-1, CREB-2, and CPEB
- (2012) Eric R Kandel Molecular Brain
- Animal models of schizophrenia
- (2011) CA Jones et al. BRITISH JOURNAL OF PHARMACOLOGY
- Cyclic nucleotide phosphodiesterase (PDE) isozymes as targets of the intracellular signalling network: benefits of PDE inhibitors in various diseases and perspectives for future therapeutic developments
- (2011) Thérèse Keravis et al. BRITISH JOURNAL OF PHARMACOLOGY
- Guanylyl cyclase structure, function and regulation
- (2011) Lincoln R. Potter CELLULAR SIGNALLING
- Effects of sildenafil and vardenafil treatments on sleep quality and depression in hemodialysis patients with erectile dysfunction
- (2011) Y Solak et al. INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH
- Enhanced long-term depression and impaired reversal learning in phosphodiesterase 4B-knockout (PDE4B−/−) mice
- (2011) Kris Rutten et al. NEUROPHARMACOLOGY
- Synergistic interactions between PDE4B and GSK-3: DISC1 mutant mice
- (2011) Tatiana V. Lipina et al. NEUROPHARMACOLOGY
- Genome-Wide Association Study in Bipolar Patients Stratified by Co-Morbidity
- (2011) Berit Kerner et al. PLoS One
- Effect of PDE10A inhibitors on MK-801-induced immobility in the forced swim test
- (2011) Barbara Langen et al. PSYCHOPHARMACOLOGY
- Investigating the role of protein kinase-G in the antidepressant-like response of sildenafil in combination with muscarinic acetylcholine receptor antagonism
- (2010) Nico Liebenberg et al. BEHAVIOURAL BRAIN RESEARCH
- A multicenter, double-blind, placebo-controlled study of sildenafil citrate in Canadian men with erectile dysfunction and untreated symptoms of depression, in the absence of major depressive disorder
- (2010) Sidney H. Kennedy et al. INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY
- Challenges and opportunities for drug discovery in psychiatric disorders: the drug hunters' perspective
- (2010) Erik H. F. Wong et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- The type IV phosphodiesterase inhibitor rolipram disturbs expression and extinction of conditioned fear in mice
- (2010) Erik M. Mueller et al. NEUROPHARMACOLOGY
- Quantitative comparison of phosphodiesterase mRNA distribution in human brain and peripheral tissues
- (2010) Viktor Lakics et al. NEUROPHARMACOLOGY
- A Double-Blind, Randomized, Placebo-Controlled 4-Week Study on the Efficacy and Safety of the Purinergic Agents Allopurinol and Dipyridamole Adjunctive to Lithium in Acute Bipolar Mania
- (2009) Rodrigo Machado-Vieira et al. JOURNAL OF CLINICAL PSYCHIATRY
- Phosphodiesterase 10A Inhibitor Activity in Preclinical Models of the Positive, Cognitive, and Negative Symptoms of Schizophrenia
- (2009) S. M. Grauer et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- ORIGINAL RESEARCH—ED PHARMACOTHERAPY: Sildenafil Citrate 100 mg Starting Dose in Men with Erectile Dysfunction in an International, Double-Blind, Placebo-Controlled Study: Effect on the Sexual Experience and Reducing Feelings of Anxiety About the Next Intercourse Attempt
- (2009) Oleg B. Loran et al. Journal of Sexual Medicine
- Antidepressant- and Anxiolytic-like Effects of the Phosphodiesterase-4 Inhibitor Rolipram on Behavior Depend on Cyclic AMP Response Element Binding Protein-Mediated Neurogenesis in the Hippocampus
- (2009) Yun-Feng Li et al. NEUROPSYCHOPHARMACOLOGY
- Regulation of amygdalar PKA by -arrestin-2/phosphodiesterase-4 complex is critical for fear conditioning
- (2009) Y. Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A new model of the disrupted latent inhibition in C57BL/6J mice after bupropion treatment
- (2009) Tatiana Lipina et al. PSYCHOPHARMACOLOGY
- Phosphodiesterase genes and antidepressant treatment response: A review
- (2008) Karin Esposito et al. ANNALS OF MEDICINE
- Enhanced long-term potentiation and impaired learning in phosphodiesterase 4D-knockout (PDE4D−/−) mice
- (2008) Kris Rutten et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- An Open-Label Pilot Study to Evaluate the Efficacy of Sildenafil Citrate in Middle-Aged Men With Late-Onset Dysthymia
- (2008) Guy Orr et al. JOURNAL OF NERVOUS AND MENTAL DISEASE
- Antipsychotic-Like Properties of Phosphodiesterase 4 Inhibitors: Evaluation of 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone (RO-20-1724) with Auditory Event-Related Potentials and Prepulse Inhibition of Startle
- (2008) T. B. Halene et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Reversal of Oxidative Stress-Induced Anxiety by Inhibition of Phosphodiesterase-2 in Mice
- (2008) A. Masood et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- The NO-cGMP-PKG signaling pathway regulates synaptic plasticity and fear memory consolidation in the lateral amygdala via activation of ERK/MAP kinase
- (2008) K. T. Ota et al. LEARNING & MEMORY
- Phosphodiesterase-4A expression is reduced in cerebella of patients with bipolar disorder
- (2008) S. Hossein Fatemi et al. PSYCHIATRIC GENETICS
- A placebo-controlled study of sildenafil effects on cognition in schizophrenia
- (2008) Donald C. Goff et al. PSYCHOPHARMACOLOGY
- PDE4B polymorphisms and decreased PDE4B expression are associated with schizophrenia
- (2008) S. Hossein Fatemi et al. SCHIZOPHRENIA RESEARCH
- Phosphodiesterase 10A inhibition is associated with locomotor and cognitive deficits and increased anxiety in mice
- (2007) Andrea L.O. Hebb et al. EUROPEAN NEUROPSYCHOPHARMACOLOGY
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started