An experimental medicine study of the phosphodiesterase-4 inhibitor, roflumilast, on working memory-related brain activity and episodic memory in schizophrenia patients

Acute administration of roflumilast enhances immediate recall of verbal word memory in healthy young adults

(2018) M.A. Van Duinen et al.   NEUROPHARMACOLOGY

The PDE4-inhibitor roflumilast improves memory: findings from a translational perspective

(2017) M.A. Van Duinen et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

The PDE4 inhibitor roflumilast improves memory in rodents at non-emetic doses

(2016) Tim Vanmierlo et al.   BEHAVIOURAL BRAIN RESEARCH

Treatment of Cognitive Impairment in Schizophrenia: Potential Value of Phosphodiesterase Inhibitors in Prefrontal Dysfunction

(2015) Marlies Duinen et al.   CURRENT PHARMACEUTICAL DESIGN

Effects of rolipram and roflumilast, phosphodiesterase-4 inhibitors, on hypertension-induced defects in memory function in rats

(2015) Sobhana George Sugin Lal Jabaris et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Effects of Selective Phosphodiesterases-4 Inhibitors on Learning and Memory: A Review of Recent Research

(2014) Sheng Peng et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Modafinil combined with cognitive training is associated with improved learning in healthy volunteers – A randomised controlled trial

(2014) J. Gilleen et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

PDE Inhibition and cognition enhancement

(2012) Arjan Blokland et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Effects of protein kinase A and G inhibitors on hippocampal cholinergic markers expressions in rolipram- and sildenafil-induced spatial memory improvement

(2012) Ali Hosseini-Sharifabad et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Selective phosphodiesterase inhibitors improve performance on the ED/ID cognitive task in rats

(2011) Joshua S. Rodefer et al.   NEUROPHARMACOLOGY

Pattern Classification of Working Memory Networks Reveals Differential Effects of Methylphenidate, Atomoxetine and Placebo in Healthy Volunteers

(2011) Andre F Marquand et al.   NEUROPSYCHOPHARMACOLOGY

Drug targets for cognitive enhancement in neuropsychiatric disorders

(2011) Tanya L. Wallace et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Phosphodiesterase 4 inhibition enhances the dopamine D1 receptor/PKA/DARPP-32 signaling cascade in frontal cortex

(2011) Mahomi Kuroiwa et al.   PSYCHOPHARMACOLOGY

Phosphodiesterase Inhibitors Enhance Object Memory Independent of Cerebral Blood Flow and Glucose Utilization in Rats

(2009) Kris Rutten et al.   NEUROPSYCHOPHARMACOLOGY

The MATRICS Consensus Cognitive Battery, Part 1: Test Selection, Reliability, and Validity

(2008) Keith H. Nuechterlein et al.   AMERICAN JOURNAL OF PSYCHIATRY