Challenges and opportunities for drug discovery in psychiatric disorders: the drug hunters' perspective
Published 2010 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Challenges and opportunities for drug discovery in psychiatric disorders: the drug hunters' perspective
Authors
Keywords
-
Journal
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
Volume 13, Issue 09, Pages 1269-1284
Publisher
Oxford University Press (OUP)
Online
2010-08-18
DOI
10.1017/s1461145710000866
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Simultaneous EEG-fMRI: Perspectives in Psychiatry
- (2012) Christoph Mulert et al. CLINICAL EEG AND NEUROSCIENCE
- Antidepressant drug action: a neuropsychological perspective
- (2010) Catherine J. Harmer DEPRESSION AND ANXIETY
- 2009 FDA drug approvals
- (2010) Bethan Hughes NATURE REVIEWS DRUG DISCOVERY
- 5-HT1A Autoreceptor Levels Determine Vulnerability to Stress and Response to Antidepressants
- (2010) Jesse W. Richardson-Jones et al. NEURON
- The effectiveness of multi-target agents in schizophrenia and mood disorders: Relevance of receptor signature to clinical action
- (2010) Erik H.F. Wong et al. PHARMACOLOGY & THERAPEUTICS
- Translating Scientific Opportunity Into Public Health Impact
- (2009) Thomas R. Insel ARCHIVES OF GENERAL PSYCHIATRY
- Epigenetic Mechanisms in Psychiatry
- (2009) Eric J. Nestler BIOLOGICAL PSYCHIATRY
- Endophenotypes: Bridging Genomic Complexity and Disorder Heterogeneity
- (2009) Thomas R. Insel et al. BIOLOGICAL PSYCHIATRY
- Pharmacoepigenetics: Its Role in Interindividual Differences in Drug Response
- (2009) A Gomez et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- The complexity of the GABAA receptor shapes unique pharmacological profiles
- (2009) Charlotte D’Hulst et al. DRUG DISCOVERY TODAY
- Early integration of pharmacokinetic and dynamic reasoning is essential for optimal development of lead compounds: strategic considerations
- (2009) Johan Gabrielsson et al. DRUG DISCOVERY TODAY
- Visualizing the drug target landscape
- (2009) Stephen J. Campbell et al. DRUG DISCOVERY TODAY
- Mirtazapine and paroxetine in major depression: A comparison of monotherapy versus their combination from treatment initiation
- (2009) Pierre Blier et al. EUROPEAN NEUROPSYCHOPHARMACOLOGY
- Interaction Between the Serotonin Transporter Gene (5-HTTLPR), Stressful Life Events, and Risk of Depression
- (2009) Neil Risch et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Disruptive insights in psychiatry: transforming a clinical discipline
- (2009) Thomas R. Insel JOURNAL OF CLINICAL INVESTIGATION
- Antidepressant Actions of Histone Deacetylase Inhibitors
- (2009) H. E. Covington et al. JOURNAL OF NEUROSCIENCE
- Common genetic determinants of schizophrenia and bipolar disorder in Swedish families: a population-based study
- (2009) Paul Lichtenstein et al. LANCET
- The moderation by the serotonin transporter gene of environmental adversity in the etiology of depression: 2009 update
- (2009) R Uher et al. MOLECULAR PSYCHIATRY
- DISC-1 Leu607Phe alleles differentially affect centrosomal PCM1 localization and neurotransmitter release
- (2009) S L Eastwood et al. MOLECULAR PSYCHIATRY
- The CRF system, stress, depression and anxiety—insights from human genetic studies
- (2009) E B Binder et al. MOLECULAR PSYCHIATRY
- Finding the missing heritability of complex diseases
- (2009) Teri A. Manolio et al. NATURE
- Predicting new molecular targets for known drugs
- (2009) Michael J. Keiser et al. NATURE
- Novel consortium to address shortfall in innovative medicines for psychiatric disorders
- (2009) Bethan Hughes NATURE REVIEWS DRUG DISCOVERY
- Lessons from 60 years of pharmaceutical innovation
- (2009) Bernard Munos NATURE REVIEWS DRUG DISCOVERY
- The role of the nucleus accumbens and rostral anterior cingulate cortex in anhedonia: Integration of resting EEG, fMRI, and volumetric techniques
- (2009) Jan Wacker et al. NEUROIMAGE
- The current state, challenges and perspectives of MR-PET
- (2009) Hans Herzog et al. NEUROIMAGE
- From synapse to nucleus: Novel targets for treating depression
- (2009) Herbert E. Covington et al. NEUROPHARMACOLOGY
- Neurocircuitry of Mood Disorders
- (2009) Joseph L Price et al. NEUROPSYCHOPHARMACOLOGY
- Criteria for validating mouse models of psychiatric diseases
- (2008) Kathryn K. Chadman et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS
- A 6-Week Randomized, Placebo-Controlled Trial of CP-316,311 (a Selective CRH1Antagonist) in the Treatment of Major Depression
- (2008) Brendon Binneman et al. AMERICAN JOURNAL OF PSYCHIATRY
- Assessing the Economic Costs of Serious Mental Illness
- (2008) Thomas R. Insel AMERICAN JOURNAL OF PSYCHIATRY
- Akt/GSK3 Signaling in the Action of Psychotropic Drugs
- (2008) Jean-Martin Beaulieu et al. Annual Review of Pharmacology and Toxicology
- Glycine Transport Inhibitors and the Treatment of Schizophrenia
- (2008) Daniel C. Javitt BIOLOGICAL PSYCHIATRY
- The State of Innovation in Drug Development
- (2008) I Kola CLINICAL PHARMACOLOGY & THERAPEUTICS
- Central auditory dysfunction in schizophrenia as revealed by the mismatch negativity (MMN) and its magnetic equivalent MMNm: a review
- (2008) Risto Näätänen et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- An Innovative Design to Establish Proof of Concept of the Antidepressant Effects of the NR2B Subunit Selective N-Methyl-D-Aspartate Antagonist, CP-101,606, in Patients With Treatment-Refractory Major Depressive Disorder
- (2008) Sheldon H. Preskorn et al. JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY
- A comparison of the effects of a subtype selective and non-selective benzodiazepine receptor agonist in two CO2 models of experimental human anxiety
- (2008) JE Bailey et al. JOURNAL OF PSYCHOPHARMACOLOGY
- Intermediate phenotypes in schizophrenia genetics redux: is it a no brainer?
- (2008) H-Y Tan et al. MOLECULAR PSYCHIATRY
- Gene-wide analyses of genome-wide association data sets: evidence for multiple common risk alleles for schizophrenia and bipolar disorder and for overlap in genetic risk
- (2008) V Moskvina et al. MOLECULAR PSYCHIATRY
- The Role of Imaging in Proof of Concept for CNS Drug Discovery and Development
- (2008) Dean F Wong et al. NEUROPSYCHOPHARMACOLOGY
- Opportunities and Challenges of Psychiatric Drug Discovery: Roles for Scientists in Academic, Industry and Government Settings
- (2008) P Jeffrey Conn et al. NEUROPSYCHOPHARMACOLOGY
- Novel Drugs and Therapeutic Targets for Severe Mood Disorders
- (2008) Sanjay J Mathew et al. NEUROPSYCHOPHARMACOLOGY
- Dual- and triple-acting agents for treating core and co-morbid symptoms of major depression: novel concepts, new drugs
- (2008) Mark J. Millan Neurotherapeutics
- Realistic expectations of prepulse inhibition in translational models for schizophrenia research
- (2008) Neal R. Swerdlow et al. PSYCHOPHARMACOLOGY
- HPA Axis Reactivity: A Mechanism Underlying the Associations Among 5-HTTLPR, Stress, and Depression
- (2007) Ian H. Gotlib et al. BIOLOGICAL PSYCHIATRY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now