A novel PDE9 inhibitor WYQ-C36D ameliorates corticosterone-induced neurotoxicity and depression-like behaviors by cGMP-CREB-related signaling
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
A novel PDE9 inhibitor WYQ-C36D ameliorates corticosterone-induced neurotoxicity and depression-like behaviors by cGMP-CREB-related signaling
Authors
Keywords
-
Journal
CNS Neuroscience & Therapeutics
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2018-05-03
DOI
10.1111/cns.12864
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Inhibition of phosphodiesterase 2 reverses impaired cognition and neuronal remodeling caused by chronic stress
- (2015) Ying Xu et al. NEUROBIOLOGY OF AGING
- Discovery of a Phosphodiesterase 9A Inhibitor as a Potential Hypoglycemic Agent
- (2014) Yong-xian Shao et al. JOURNAL OF MEDICINAL CHEMISTRY
- Advances in targeting cyclic nucleotide phosphodiesterases
- (2014) Donald H. Maurice et al. NATURE REVIEWS DRUG DISCOVERY
- Mechanisms underlying the antidepressant response and treatment resistance
- (2014) Marjorie R. Levinstein et al. Frontiers in Behavioral Neuroscience
- Antidepressant-like responses in the forced swimming test elicited by glutathione and redox modulation
- (2013) Juliana M. Rosa et al. BEHAVIOURAL BRAIN RESEARCH
- Tau Protein Phosphorylation in Diverse Brain Areas of Normal and CRH Deficient Mice: Up-Regulation by Stress
- (2012) Peter Filipcik et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- Phosphodiesterase-2 inhibitor reverses corticosterone-induced neurotoxicity and related behavioural changes via cGMP/PKG dependent pathway
- (2012) Ying Xu et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- Design and Discovery of 6-[(3S,4S)-4-Methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-1-(tetrahydro-2H-pyran-4-yl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (PF-04447943), a Selective Brain Penetrant PDE9A Inhibitor for the Treatment of Cognitive Disorders
- (2012) Patrick R. Verhoest et al. JOURNAL OF MEDICINAL CHEMISTRY
- Application of Structure-Based Drug Design and Parallel Chemistry to Identify Selective, Brain Penetrant, In Vivo Active Phosphodiesterase 9A Inhibitors
- (2012) Michelle M. Claffey et al. JOURNAL OF MEDICINAL CHEMISTRY
- Structure-Based Discovery of Highly Selective Phosphodiesterase-9A Inhibitors and Implications for Inhibitor Design
- (2012) Fei Meng et al. JOURNAL OF MEDICINAL CHEMISTRY
- The Selective Phosphodiesterase 9 (PDE9) Inhibitor PF-04447943 Attenuates a Scopolamine-Induced Deficit in a Novel Rodent Attention Task
- (2011) Joshua D. Vardigan et al. JOURNAL OF NEUROGENETICS
- Hippocampal Neuronal Nitric Oxide Synthase Mediates the Stress-Related Depressive Behaviors of Glucocorticoids by Downregulating Glucocorticoid Receptor
- (2011) Q.-G. Zhou et al. JOURNAL OF NEUROSCIENCE
- Corticosterone induced morphological changes of hippocampal and amygdaloid cell lines are dependent on 5-HT7 receptor related signal pathway
- (2011) Y. Xu et al. NEUROSCIENCE
- Regulation of Genotoxic Stress Response by Homeodomain-interacting Protein Kinase 2 through Phosphorylation of Cyclic AMP Response Element-binding Protein at Serine 271
- (2010) Kensuke Sakamoto et al. MOLECULAR BIOLOGY OF THE CELL
- Acute Stress Impairs Hippocampal Mossy Fiber-CA3 Long-Term Potentiation by Enhancing cAMP-Specific Phosphodiesterase 4 Activity
- (2010) Chien-Chung Chen et al. NEUROPSYCHOPHARMACOLOGY
- Curcumin reverses impaired cognition and neuronal plasticity induced by chronic stress
- (2009) Ying Xu et al. NEUROPHARMACOLOGY
- Reversal of Oxidative Stress-Induced Anxiety by Inhibition of Phosphodiesterase-2 in Mice
- (2008) A. Masood et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- HT22 hippocampal neuronal cell line possesses functional cholinergic properties
- (2008) Jun Liu et al. LIFE SCIENCES
- The novel selective PDE9 inhibitor BAY 73-6691 improves learning and memory in rodents
- (2008) F. Josef van der Staay et al. NEUROPHARMACOLOGY
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now