The Role of Iron Metabolism, Lipid Metabolism, and Redox Homeostasis in Alzheimer’s Disease: from the Perspective of Ferroptosis

Loss of ferroportin induces memory impairment by promoting ferroptosis in Alzheimer’s disease

(2021) Wen-Dai Bao et al.   CELL DEATH AND DIFFERENTIATION

Correction to: Effects of Brazil nut consumption on selenium status and cognitive performance in older adults with mild cognitive impairment: a randomized controlled pilot trial

(2021) Barbara Rita Cardoso et al.   EUROPEAN JOURNAL OF NUTRITION

The Potential Role of Ferroptosis in Alzheimer’s Disease

(2021) Guimei Zhang et al.   JOURNAL OF ALZHEIMERS DISEASE

Ginkgolide B Maintains Calcium Homeostasis in Hypoxic Hippocampal Neurons by Inhibiting Calcium Influx and Intracellular Calcium Release

(2021) Li Wang et al.   Frontiers in Cellular Neuroscience

Alteration of Iron Concentration in Alzheimer’s Disease as a Possible Diagnostic Biomarker Unveiling Ferroptosis

(2021) Eleonora Ficiarà et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

N2L, a novel lipoic acid-niacin dimer, attenuates ferroptosis and decreases lipid peroxidation in HT22 cells

(2021) Weijia Peng et al.   BRAIN RESEARCH BULLETIN

Ferroptosis: A potential therapeutic target for neurodegenerative diseases

(2021) D. Vitalakumar et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Ferroptosis as a mechanism of neurodegeneration in Alzheimer's disease

(2021) Md. Jakaria et al.   JOURNAL OF NEUROCHEMISTRY

Mechanisms of Modulation of Ferroptosis and Its Role in Central Nervous System Diseases

(2021) Qingyun Tan et al.   Frontiers in Pharmacology

Ferroptosis, a Potential Therapeutic Target in Alzheimer’s Disease

(2021) Kai Chen et al.   Frontiers in Cell and Developmental Biology

Ginkgolide B protects against cognitive impairment in senescence-accelerated P8 mice by mitigating oxidative stress, inflammation and ferroptosis

(2021) Li Shao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Tetrahydroxy stilbene glycoside ameliorates Alzheimer’s disease in APP/PS1 mice via glutathione peroxidase related ferroptosis

(2021) Yan Gao et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Ferroptosis Mediated by Lipid Reactive Oxygen Species: A Possible Causal Link of Neuroinflammation to Neurological Disorders

(2021) Ying Cheng et al.   Oxidative Medicine and Cellular Longevity

Iron Metabolism, Ferroptosis, and the Links With Alzheimer’s Disease

(2020) Nao Yan et al.   Frontiers in Neuroscience

BRAIN LIPID PEROXIDATION AND ALZHEIMER DISEASE: SYNERGY BETWEEN THE BUTTERFIELD AND MATTSON LABORATORIES

(2020) D. Allan Butterfield   AGEING RESEARCH REVIEWS

Association Between Ambient Air Pollution and Daily Hospital Admissions for Depression in 75 Chinese Cities

(2020) Xuelin Gu et al.   AMERICAN JOURNAL OF PSYCHIATRY

Amyloidogenic processing of Alzheimer’s disease β-amyloid precursor protein induces cellular iron retention

(2020) Andrew Tsatsanis et al.   MOLECULAR PSYCHIATRY

Association of Plasma Transferrin With Cognitive Decline in Patients With Mild Cognitive Impairment and Alzheimer’s Disease

(2020) Jingjing Guan et al.   Frontiers in Aging Neuroscience

Preventive and Therapeutic Strategies in Alzheimer's Disease: Focus on Oxidative Stress, Redox Metals, and Ferroptosis

(2020) Germán Plascencia-Villa et al.   ANTIOXIDANTS & REDOX SIGNALING

Iron promotes the clearance of α‐synuclein

(2020) Qing‐Zhang Tuo et al.   JOURNAL OF NEUROCHEMISTRY

Increase in blood–brain barrier leakage in healthy, older adults

(2020) Inge C. M. Verheggen et al.   GeroScience

The Iron Chelator Deferiprone Improves the Phenotype in a Mouse Model of Tauopathy

(2020) Shalini S. Rao et al.   JOURNAL OF ALZHEIMERS DISEASE

The Application of Ferroptosis in Diseases

(2020) Yangmin Qiu et al.   PHARMACOLOGICAL RESEARCH

α‐Lipoic acid alleviates ferroptosis in the MPP + ‐induced PC12 cells via activating the PI3K/Akt/Nrf2 pathway

(2020) Lin Liu et al.   CELL BIOLOGY INTERNATIONAL

Ferroptosis: molecular mechanisms and health implications

(2020) Daolin Tang et al.   CELL RESEARCH

Ferroptosis Mechanisms Involved in Neurodegenerative Diseases

(2020) Cadiele Oliana Reichert et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Association of Brain Iron Overload With Brain Edema and Brain Atrophy After Intracerebral Hemorrhage

(2020) Ran Liu et al.   Frontiers in Neurology

Iron accumulation in microglia triggers a cascade of events that leads to altered metabolism and compromised function in APP/PS1 mice

(2019) Allison McIntosh et al.   BRAIN PATHOLOGY

Treating Alzheimer's disease by targeting iron

(2019) Sara Nikseresht et al.   BRITISH JOURNAL OF PHARMACOLOGY

NRF2 plays a critical role in mitigating lipid peroxidation and ferroptosis

(2019) Matthew Dodson et al.   Redox Biology

Iron in Neurodegeneration – Cause or Consequence?

(2019) Alain Ndayisaba et al.   Frontiers in Neuroscience

Brain iron is associated with accelerated cognitive decline in people with Alzheimer pathology

(2019) Scott Ayton et al.   MOLECULAR PSYCHIATRY

Ferroptosis and Brain Injury

(2019) Leslie Magtanong et al.   DEVELOPMENTAL NEUROSCIENCE

Selenium Drives a Transcriptional Adaptive Program to Block Ferroptosis and Treat Stroke

(2019) Ishraq Alim et al.   CELL

Iron Deposition Leads to Hyperphosphorylation of Tau and Disruption of Insulin Signaling

(2019) Wenbin Wan et al.   Frontiers in Neurology

Clinical utility of serum hepcidin and iron profile measurements in Alzheimer's disease

(2019) Oh Joo Kweon et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

The role of zinc, copper, manganese and iron in neurodegenerative diseases

(2019) Leda Mezzaroba et al.   NEUROTOXICOLOGY

Alzheimer Disease: An Update on Pathobiology and Treatment Strategies

(2019) Justin M. Long et al.   CELL

Iron Potentiates Microglial Interleukin‐1β Secretion Induced by Amyloid‐β

(2019) Israel C. Nnah et al.   JOURNAL OF NEUROCHEMISTRY

The chemical basis of ferroptosis

(2019) Marcus Conrad et al.   Nature Chemical Biology

Revisiting the intersection of amyloid, pathologically modified tau and iron in Alzheimer’s disease from a ferroptosis perspective

(2019) Paul J. Derry et al.   PROGRESS IN NEUROBIOLOGY

Selenium Utilization by GPX4 Is Required to Prevent Hydroperoxide-Induced Ferroptosis

(2018) Irina Ingold et al.   CELL

Metal Ion Effects on Aβ and Tau Aggregation

(2018) Anne Kim et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Iron and Alzheimer’s Disease: An Update on Emerging Mechanisms

(2018) Darius J.R. Lane et al.   JOURNAL OF ALZHEIMERS DISEASE

Oxidative Stress, Amyloid-β Peptide, and Altered Key Molecular Pathways in the Pathogenesis and Progression of Alzheimer’s Disease

(2018) D. Allan Butterfield et al.   JOURNAL OF ALZHEIMERS DISEASE

Postmortem MRI and histology demonstrate differential iron accumulation and cortical myelin organization in early- and late-onset Alzheimer's disease

(2018) Marjolein Bulk et al.   NEUROBIOLOGY OF AGING

Association of GPX1 and GPX4 polymorphisms with episodic memory and Alzheimer’s disease

(2018) Tatiane Jacobsen da Rocha et al.   NEUROSCIENCE LETTERS

Comparison of the effects of selenomethionine and selenium-enriched yeast in the triple-transgenic mouse model of Alzheimer's disease

(2018) Zhong-Hao Zhang et al.   Food & Function

α-Lipoic acid improves abnormal behavior by mitigation of oxidative stress, inflammation, ferroptosis, and tauopathy in P301S Tau transgenic mice

(2018) Yan-Hui Zhang et al.   Redox Biology

Deferiprone Reduces Amyloid-β and Tau Phosphorylation Levels but not Reactive Oxygen Species Generation in Hippocampus of Rabbits Fed a Cholesterol-Enriched Diet

(2018) Jaya R.P. Prasanthi et al.   JOURNAL OF ALZHEIMERS DISEASE

Role of Brain Iron Accumulation in Cognitive Dysfunction: Evidence from Animal Models and Human Studies

(2018) Nadja Schröder et al.   JOURNAL OF ALZHEIMERS DISEASE

Increased Iron Levels and Decreased Tissue Integrity in Hippocampus of Alzheimer's Disease Detected in vivo with Magnetic Resonance Imaging

(2018) Erika P. Raven et al.   JOURNAL OF ALZHEIMERS DISEASE

Marked Age-Related Changes in Brain Iron Homeostasis in Amyloid Protein Precursor Knockout Mice

(2018) Abdel A. Belaidi et al.   Neurotherapeutics

Vitamin E hydroquinone is an endogenous regulator of ferroptosis via redox control of 15-lipoxygenase

(2018) Andrew Hinman et al.   PLoS One

Untangling Tau and Iron: Exploring the Interaction Between Iron and Tau in Neurodegeneration

(2018) Shalini S. Rao et al.   Frontiers in Molecular Neuroscience

A review on iron chelators as potential therapeutic agents for the treatment of Alzheimer’s and Parkinson’s diseases

(2018) Yash Pal Singh et al.   MOLECULAR DIVERSITY

Role of 4-hydroxy-2-nonenal (HNE) in the pathogenesis of alzheimer disease and other selected age-related neurodegenerative disorders

(2017) Fabio Di Domenico et al.   FREE RADICAL BIOLOGY AND MEDICINE

Role of Vitamin E in the Treatment of Alzheimer’s Disease: Evidence from Animal Models

(2017) Agnese Gugliandolo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Phytochemical Ginkgolide B Attenuates Amyloid-β1-42 Induced Oxidative Damage and Altered Cellular Responses in Human Neuroblastoma SH-SY5Y Cells

(2017) Iqbal Gill et al.   JOURNAL OF ALZHEIMERS DISEASE

Evidence that iron accelerates Alzheimer’s pathology: a CSF biomarker study

(2017) Scott Ayton et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Elevated plasma ferritin in elderly individuals with high neocortical amyloid-β load

(2017) K Goozee et al.   MOLECULAR PSYCHIATRY

Iron addiction: a novel therapeutic target in ovarian cancer

(2017) D Basuli et al.   ONCOGENE

Association of Antioxidant Supplement Use and Dementia in the Prevention of Alzheimer’s Disease by Vitamin E and Selenium Trial (PREADViSE)

(2017) Richard J. Kryscio et al.   JAMA Neurology

Association of Cerebrospinal Fluid Ferritin Level With Preclinical Cognitive Decline in APOE-ε4 Carriers

(2017) Scott Ayton et al.   JAMA Neurology

Three-Dimensional Tomographic Imaging and Characterization of Iron Compounds within Alzheimer's Plaque Core Material

(2017) Joanna F. Collingwood et al.   JOURNAL OF ALZHEIMERS DISEASE

Clioquinol Decreases Amyloid-β Burden and Reduces Working Memory Impairment in a Transgenic Mouse Model of Alzheimer's Disease

(2017) Cristina Grossi et al.   JOURNAL OF ALZHEIMERS DISEASE

NMR Studies of Zinc, Copper, and Iron Binding to Histidine, the Principal Metal Ion Complexing Site of Amyloid-β Peptide

(2017) Nanditha G. Nair et al.   JOURNAL OF ALZHEIMERS DISEASE

Brain iron chelation by deferiprone in a phase 2 randomised double-blinded placebo controlled clinical trial in Parkinson’s disease

(2017) Antonio Martin-Bastida et al.   Scientific Reports

Identification of ACSL4 as a biomarker and contributor of ferroptosis

(2016) Hua Yuan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Iron uptake and transport across physiological barriers

(2016) Kari A. Duck et al.   BIOMETALS

Regulated cell death and adaptive stress responses

(2016) Lorenzo Galluzzi et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Activation of the NLRP3 inflammasome by cellular labile iron

(2016) Kyohei Nakamura et al.   EXPERIMENTAL HEMATOLOGY

Pre-treatment of rats with ad-hepcidin prevents iron-induced oxidative stress in the brain

(2016) Jing Gong et al.   FREE RADICAL BIOLOGY AND MEDICINE

Iron Regulates Apolipoprotein E Expression and Secretion in Neurons and Astrocytes

(2016) He Xu et al.   JOURNAL OF ALZHEIMERS DISEASE

Patterns of Brain Iron Accumulation in Vascular Dementia and Alzheimer’s Dementia Using Quantitative Susceptibility Mapping Imaging

(2016) Yeonsil Moon et al.   JOURNAL OF ALZHEIMERS DISEASE

Prochelator strategies for site-selective activation of metal chelators

(2016) Valentina Oliveri et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

The Complex Role of Apolipoprotein E in Alzheimer’s Disease: an Overview and Update

(2016) Laura Mahoney-Sanchez et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Iron neurochemistry in Alzheimer's disease and Parkinson's disease: targets for therapeutics

(2016) Abdel A. Belaidi et al.   JOURNAL OF NEUROCHEMISTRY

Glutathione peroxidase 4: a new player in neurodegeneration?

(2016) B R Cardoso et al.   MOLECULAR PSYCHIATRY

Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis

(2016) Valerian E Kagan et al.   Nature Chemical Biology

ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition

(2016) Sebastian Doll et al.   Nature Chemical Biology

A combination of an iron chelator with an antioxidant effectively diminishes the dendritic loss, tau-hyperphosphorylation, amyloids-β accumulation and brain mitochondrial dynamic disruption in rats with chronic iron-overload

(2016) Jirapas Sripetchwandee et al.   NEUROSCIENCE

Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis

(2016) Wan Seok Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ferroptosis: Death by Lipid Peroxidation

(2016) Wan Seok Yang et al.   TRENDS IN CELL BIOLOGY

Ferroptosis is induced following siramesine and lapatinib treatment of breast cancer cells

(2016) S Ma et al.   Cell Death & Disease

Mammalian lipoxygenases and their biological relevance

(2015) Hartmut Kuhn et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Tau reduction prevents Aβ-induced axonal transport deficits by blocking activation of GSK3β

(2015) Keith A. Vossel et al.   JOURNAL OF CELL BIOLOGY

Parkinson's Disease Iron Deposition Caused by Nitric Oxide-Induced Loss of  -Amyloid Precursor Protein

(2015) S. Ayton et al.   JOURNAL OF NEUROSCIENCE

Neurodegenerative diseases and therapeutic strategies using iron chelators

(2015) Roberta J. Ward et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Expression of Iron-Related Proteins at the Neurovascular Unit Supports Reduction and Reoxidation of Iron for Transport Through the Blood-Brain Barrier

(2015) Annette Burkhart et al.   MOLECULAR NEUROBIOLOGY

Ferroptosis as a p53-mediated activity during tumour suppression

(2015) Le Jiang et al.   NATURE

Tau in physiology and pathology

(2015) Yipeng Wang et al.   NATURE REVIEWS NEUROSCIENCE

7T T2∗-weighted magnetic resonance imaging reveals cortical phase differences between early- and late-onset Alzheimer's disease

(2015) Sanneke van Rooden et al.   NEUROBIOLOGY OF AGING

The relationship between iron dyshomeostasis and amyloidogenesis in Alzheimer's disease: Two sides of the same coin

(2015) Douglas G. Peters et al.   NEUROBIOLOGY OF DISEASE

Detailed comparison of amyloid PET and CSF biomarkers for identifying early Alzheimer disease

(2015) Sebastian Palmqvist et al.   NEUROLOGY

Intranasal deferoxamine engages multiple pathways to decrease memory loss in the APP/PS1 model of amyloid accumulation

(2015) Jared M. Fine et al.   NEUROSCIENCE LETTERS

Ferritin levels in the cerebrospinal fluid predict Alzheimer’s disease outcomes and are regulated by APOE

(2015) Scott Ayton et al.   Nature Communications

Age-related iron deposition in the basal ganglia of controls and Alzheimer disease patients quantified using susceptibility weighted imaging

(2014) Dan Wang et al.   ARCHIVES OF GERONTOLOGY AND GERIATRICS

Golgi defects enhance APP amyloidogenic processing in Alzheimer's disease

(2014) Gunjan Joshi et al.   BIOESSAYS

Evaluation of Selenium, Redox Status and Their Association with Plasma Amyloid/Tau in Alzheimer’s Disease

(2014) Sreeram Krishnan et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Regulation of Ferroptotic Cancer Cell Death by GPX4

(2014) Wan Seok Yang et al.   CELL

Effect of Vitamin E and Memantine on Functional Decline in Alzheimer Disease

(2014) Maurice W. Dysken et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The role of iron in brain ageing and neurodegenerative disorders

(2014) Roberta J Ward et al.   LANCET NEUROLOGY

Hepcidin Suppresses Brain Iron Accumulation by Downregulating Iron Transport Proteins in Iron-Overloaded Rats

(2014) Fang Du et al.   MOLECULAR NEUROBIOLOGY

Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

(2014) Jose Pedro Friedmann Angeli et al.   NATURE CELL BIOLOGY

Iron overload accelerates neuronal amyloid-β production and cognitive impairment in transgenic mice model of Alzheimer's disease

(2014) Javier Becerril-Ortega et al.   NEUROBIOLOGY OF AGING

Lipid Peroxidation: Production, Metabolism, and Signaling Mechanisms of Malondialdehyde and 4-Hydroxy-2-Nonenal

(2014) Antonio Ayala et al.   Oxidative Medicine and Cellular Longevity

Combined Therapy of Iron Chelator and Antioxidant Completely Restores Brain Dysfunction Induced by Iron Toxicity

(2014) Jirapas Sripetchwandee et al.   PLoS One

β-Amyloid Precursor Protein Does Not Possess Ferroxidase Activity but Does Stabilize the Cell Surface Ferrous Iron Exporter Ferroportin

(2014) Bruce X. Wong et al.   PLoS One

Human astrocytes express a novel NLRP2 inflammasome

(2013) Julia Minkiewicz et al.   GLIA

Reversal of Metabolic Deficits by Lipoic Acid in a Triple Transgenic Mouse Model of Alzheimer's Disease: A 13C NMR Study

(2013) Harsh Sancheti et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Mapping of the N-Linked Glycoproteome of Human Spermatozoa

(2013) Gaigai Wang et al.   JOURNAL OF PROTEOME RESEARCH

Iron levels in the human brain: A post-mortem study of anatomical region differences and age-related changes

(2013) Patrícia Ramos et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Enhanced Brain Delivery of Deferasirox–Lactoferrin Conjugates for Iron Chelation Therapy in Neurodegenerative Disorders: In Vitro and in Vivo Studies

(2013) Golnaz Kamalinia et al.   MOLECULAR PHARMACEUTICS

Age-Dependent Modulation of Synaptic Plasticity and Insulin Mimetic Effect of Lipoic Acid on a Mouse Model of Alzheimer’s Disease

(2013) Harsh Sancheti et al.   PLoS One

The Correlation of Hippocampal T2-Mapping with Neuropsychology Test in Patients with Alzheimer’s Disease

(2013) Zhuren Luo et al.   PLoS One

Neuropathological Alterations in Alzheimer Disease

(2013) A. Serrano-Pozo et al.   Cold Spring Harbor Perspectives in Medicine

A delicate balance: Iron metabolism and diseases of the brain

(2013) Dominic Hare et al.   Frontiers in Aging Neuroscience

The systemic iron-regulatory proteins hepcidin and ferroportin are reduced in the brain in Alzheimer’s disease

(2013) Animesh Raha et al.   Acta Neuropathologica Communications

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

A Reversible Early Oxidized Redox State That Precedes Macromolecular ROS Damage in Aging Nontransgenic and 3xTg-AD Mouse Neurons

(2012) D. Ghosh et al.   JOURNAL OF NEUROSCIENCE

Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export

(2012) Peng Lei et al.   NATURE MEDICINE

Intranasal deferoxamine reverses iron-induced memory deficits and inhibits amyloidogenic APP processing in a transgenic mouse model of Alzheimer's disease

(2012) Chuang Guo et al.   NEUROBIOLOGY OF AGING

Deferoxamine inhibits iron induced hippocampal tau phosphorylation in the Alzheimer transgenic mouse brain

(2012) Chuang Guo et al.   NEUROCHEMISTRY INTERNATIONAL

An Investigation of Age-Related Iron Deposition Using Susceptibility Weighted Imaging

(2012) Dan Wang et al.   PLoS One

Intranasal delivery of deferoxamine reduces spatial memory loss in APP/PS1 mice

(2012) Leah R. Hanson et al.   Drug Delivery and Translational Research

Pharmacologic Blockade of 5-Lipoxygenase Improves the Amyloidotic Phenotype of an Alzheimer's Disease Transgenic Mouse Model

(2011) Jin Chu et al.   AMERICAN JOURNAL OF PATHOLOGY

Hepcidin Treatment Modulates the Expression of Divalent Metal Transporter-1, Ceruloplasmin, and Ferroportin-1 in the Rat Cerebral Cortex and Hippocampus

(2011) Lin Li et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Glutathione: a key component of the cytoplasmic labile iron pool

(2011) Robert C. Hider et al.   BIOMETALS

The Alzheimer’s therapeutic PBT2 promotes amyloid-β degradation and GSK3 phosphorylation via a metal chaperone activity

(2011) Peter J. Crouch et al.   JOURNAL OF NEUROCHEMISTRY

Amelioration of social isolation-triggered onset of early Alzheimer's disease-related cognitive deficit by N-acetylcysteine in a transgenic mouse model

(2011) Ya-Hsin Hsiao et al.   NEUROBIOLOGY OF DISEASE

5-lipoxygenase as an endogenous modulator of amyloid beta formation in vivo

(2010) Jin Chu et al.   ANNALS OF NEUROLOGY

Iron-Export Ferroxidase Activity of β-Amyloid Precursor Protein Is Inhibited by Zinc in Alzheimer's Disease

(2010) James A. Duce et al.   CELL

Selective Translational Control of the Alzheimer Amyloid Precursor Protein Transcript by Iron Regulatory Protein-1

(2010) Hyun-Hee Cho et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oxidative Stress in the Progression of Alzheimer Disease in the Frontal Cortex

(2010) Mubeen A. Ansari et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Delineating the Role of Glutathione Peroxidase 4 in Protecting Cells Against Lipid Hydroperoxide Damage and in Alzheimer's Disease

(2009) Min-Hyuk Yoo et al.   ANTIOXIDANTS & REDOX SIGNALING

Lipid peroxidation: Physiological levels and dual biological effects

(2009) Etsuo Niki   FREE RADICAL BIOLOGY AND MEDICINE

Mechanisms of brain iron transport: insight into neurodegeneration and CNS disorders

(2009) Eric Mills et al.   Future Medicinal Chemistry

Innate immunity and neuroinflammation in the CNS: The role of microglia in Toll-like receptor-mediated neuronal injury

(2009) Seija Lehnardt   GLIA

MRI and histological analysis of beta-amyloid plaques in both human Alzheimer's disease and APP/PS1 transgenic mice

(2009) Mark D. Meadowcroft et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Age-related Iron Deposition in the Basal Ganglia: Quantitative Analysis in Healthy Subjects

(2009) Domenico Aquino et al.   RADIOLOGY

Evolutionary and Structural Insights Into the Multifaceted Glutathione Peroxidase (Gpx) Superfamily

(2008) Stefano Toppo et al.   ANTIOXIDANTS & REDOX SIGNALING

Iron and the translation of the amyloid precursor protein (APP) and ferritin mRNAs: riboregulation against neural oxidative damage in Alzheimer's disease

(2008) Jack T. Rogers et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Synthetic Lethal Screening Identifies Compounds Activating Iron-Dependent, Nonapoptotic Cell Death in Oncogenic-RAS-Harboring Cancer Cells

(2008) Wan Seok Yang et al.   CHEMISTRY & BIOLOGY

Brain oxidative stress in a triple-transgenic mouse model of Alzheimer disease

(2008) Rosa Resende et al.   FREE RADICAL BIOLOGY AND MEDICINE

Elevated levels of pro-apoptotic p53 and its oxidative modification by the lipid peroxidation product, HNE,in brain from subjects with amnestic mild cognitive impairment and Alzheimer's disease

(2008) Giovanna Cenini et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Hepcidin Regulation of Iron Transport

(2008) James F. Collins et al.   JOURNAL OF NUTRITION