Iron Regulates Apolipoprotein E Expression and Secretion in Neurons and Astrocytes

Quantitative Susceptibility Mapping by Inversion of a Perturbation Field Model: Correlation With Brain Iron in Normal Aging

(2015) Clare B. Poynton et al.   IEEE TRANSACTIONS ON MEDICAL IMAGING

Iron misregulation and neurodegenerative disease in mouse models that lack iron regulatory proteins

(2015) Manik C. Ghosh et al.   NEUROBIOLOGY OF DISEASE

The relationship between iron dyshomeostasis and amyloidogenesis in Alzheimer's disease: Two sides of the same coin

(2015) Douglas G. Peters et al.   NEUROBIOLOGY OF DISEASE

Clioquinol rescues Parkinsonism and dementia phenotypes of the tau knockout mouse

(2015) Peng Lei et al.   NEUROBIOLOGY OF DISEASE

Ferritin levels in the cerebrospinal fluid predict Alzheimer’s disease outcomes and are regulated by APOE

(2015) Scott Ayton et al.   Nature Communications

Iron increases APP translation and amyloid-beta production in the retina

(2014) Lucie Y. Guo et al.   EXPERIMENTAL EYE RESEARCH

The role of iron in brain ageing and neurodegenerative disorders

(2014) Roberta J Ward et al.   LANCET NEUROLOGY

Iron accumulation confers neurotoxicity to a vulnerable population of nigral neurons: implications for Parkinson’s disease

(2014) Scott Ayton et al.   Molecular Neurodegeneration

Apolipoprotein E and lipid homeostasis in the etiology and treatment of sporadic Alzheimer's disease

(2014) Judes Poirier et al.   NEUROBIOLOGY OF AGING

Apolipoprotein E: Structure and function in lipid metabolism, neurobiology, and Alzheimer's diseases

(2014) Yadong Huang et al.   NEUROBIOLOGY OF DISEASE

MRI for Iron Mapping in Alzheimer's Disease

(2014) Christian Langkammer et al.   Neurodegenerative Diseases

Apolipoprotein E, amyloid-beta, and neuroinflammation in Alzheimer’s disease

(2014) Evan Dorey et al.   Neuroscience Bulletin

Brain Iron Homeostasis: From Molecular Mechanisms To Clinical Significance and Therapeutic Opportunities

(2013) Neena Singh et al.   ANTIOXIDANTS & REDOX SIGNALING

Iron levels in the human brain: A post-mortem study of anatomical region differences and age-related changes

(2013) Patrícia Ramos et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Altered APP Carboxyl-Terminal Processing Under Ferrous Iron Treatment in PC12 Cells

(2013) Chi Hyun Kim et al.   KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY

Profiling the iron, copper and zinc content in primary neuron and astrocyte cultures by rapid online quantitative size exclusion chromatography-inductively coupled plasma-mass spectrometry

(2013) Dominic J. Hare et al.   Metallomics

Both Targeted Mass Spectrometry and Flow Sorting Analysis Methods Detected the Decreased Serum Apolipoprotein E Level in Alzheimer's Disease Patients

(2013) Sun-Ho Han et al.   MOLECULAR & CELLULAR PROTEOMICS

ApoE influences amyloid-  (A ) clearance despite minimal apoE/A  association in physiological conditions

(2013) P. B. Verghese et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Apolipoprotein E and Apolipoprotein E Receptors: Normal Biology and Roles in Alzheimer Disease

(2013) D. M. Holtzman et al.   Cold Spring Harbor Perspectives in Medicine

Low-density Lipoprotein Receptor Represents an Apolipoprotein E-independent Pathway of Aβ Uptake and Degradation by Astrocytes

(2012) Jacob M. Basak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metal dyshomeostasis and oxidative stress in Alzheimer’s disease

(2012) Mark A. Greenough et al.   NEUROCHEMISTRY INTERNATIONAL

LRP-1 and LRP-2 receptors function in the membrane neuron. Trafficking mechanisms and proteolytic processing in Alzheimer's disease

(2012) Carlos Spuch et al.   Frontiers in Physiology

Association of ApoE and LRP mRNA levels with dementia and AD neuropathology

(2011) Afia Akram et al.   NEUROBIOLOGY OF AGING

MRI estimates of brain iron concentration in normal aging using quantitative susceptibility mapping

(2011) Berkin Bilgic et al.   NEUROIMAGE

Plasma apolipoprotein E and Alzheimer disease risk: The AIBL study of aging

(2011) V. B. Gupta et al.   NEUROLOGY

Metal Ionophore Treatment Restores Dendritic Spine Density and Synaptic Protein Levels in a Mouse Model of Alzheimer's Disease

(2011) Paul A. Adlard et al.   PLoS One

Apolipoprotein E: Isoform Specific Differences in Tertiary Structure and Interaction with Amyloid-β in Human Alzheimer Brain

(2011) Phillip B. Jones et al.   PLoS One

Apolipoprotein E ablation decreases synaptic vesicular zinc in the brain

(2010) Joo-Yong Lee et al.   BIOMETALS

Brain lipid metabolism, apolipoprotein E and the pathophysiology of Alzheimer's disease

(2010) Kelly R. Bales   NEUROPHARMACOLOGY

Aβ-independent roles of apolipoprotein E4 in the pathogenesis of Alzheimer's disease

(2010) Yadong Huang   TRENDS IN MOLECULAR MEDICINE

Ternary Complexes of Iron, Amyloid-β, and Nitrilotriacetic Acid: Binding Affinities, Redox Properties, and Relevance to Iron-Induced Oxidative Stress in Alzheimer’s Disease

(2009) Dianlu Jiang et al.   BIOCHEMISTRY

Genetic Interaction between Tau and the Apolipoprotein E Receptor LRP1 Increases Alzheimer’s Disease Risk

(2009) José Luis Vázquez-Higuera et al.   DEMENTIA AND GERIATRIC COGNITIVE DISORDERS

Genome-wide association studies in Alzheimer's disease

(2009) L. Bertram et al.   HUMAN MOLECULAR GENETICS

Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy

(2009) Guojun Bu   NATURE REVIEWS NEUROSCIENCE

Overexpression of Low-Density Lipoprotein Receptor in the Brain Markedly Inhibits Amyloid Deposition and Increases Extracellular Aβ Clearance

(2009) Jungsu Kim et al.   NEURON

Iron and the translation of the amyloid precursor protein (APP) and ferritin mRNAs: riboregulation against neural oxidative damage in Alzheimer's disease

(2008) Jack T. Rogers et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Physiological and pathological aspects of Aβ in iron homeostasis via 5'UTR in the APP mRNA and the therapeutic use of iron-chelators

(2008) Yael Avramovich-Tirosh et al.   BMC NEUROSCIENCE