The systemic iron-regulatory proteins hepcidin and ferroportin are reduced in the brain in Alzheimer’s disease

Inflammation alters the expression of DMT1, FPN1 and hepcidin, and it causes iron accumulation in central nervous system cells

(2013) Pamela Urrutia et al.   JOURNAL OF NEUROCHEMISTRY

Decreased iron levels in the temporal cortex in postmortem human brains with Parkinson disease

(2013) X. Yu et al.   NEUROLOGY

Deficiency in Mural Vascular Cells Coincides with Blood-Brain Barrier Disruption in Alzheimer's Disease

(2012) Jesse D. Sengillo et al.   BRAIN PATHOLOGY

Iron homeostasis in astrocytes and microglia is differentially regulated by TNF-α and TGF-β1

(2012) Khizr I. Rathore et al.   GLIA

Blood–Spinal Cord Barrier Pericyte Reductions Contribute to Increased Capillary Permeability

(2012) Ethan A Winkler et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Interactions between Amyloid-β and Hemoglobin: Implications for Amyloid Plaque Formation in Alzheimer's Disease

(2012) Jia-Ying Chuang et al.   PLoS One

Vascular β-amyloid and early astrocyte alterations impair cerebrovascular function and cerebral metabolism in transgenic arcAβ mice

(2011) Mario Merlini et al.   ACTA NEUROPATHOLOGICA

Intraneuronal Aβ as a trigger for neuron loss: can this be translated into human pathology?

(2011) Thomas A. Bayer et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Hepcidin Treatment Modulates the Expression of Divalent Metal Transporter-1, Ceruloplasmin, and Ferroportin-1 in the Rat Cerebral Cortex and Hippocampus

(2011) Lin Li et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Hepcidin and iron regulation, 10 years later

(2011) T. Ganz   BLOOD

Comparison of changes in gene expression of transferrin receptor-1 and other iron-regulatory proteins in rat liver and brain during acute-phase response

(2011) Ihtzaz Ahmed Malik et al.   CELL AND TISSUE RESEARCH

Neurovascular dysfunction, inflammation and endothelial activation: Implications for the pathogenesis of Alzheimer's disease

(2011) Paula Grammas   Journal of Neuroinflammation

Role of metal dyshomeostasis in Alzheimer's disease

(2011) David J. Bonda et al.   Metallomics

Syndromes of neurodegeneration with brain iron accumulation (NBIA): An update on clinical presentations, histological and genetic underpinnings, and treatment considerations

(2011) Susanne A. Schneider et al.   MOVEMENT DISORDERS

Central nervous system pericytes in health and disease

(2011) Ethan A Winkler et al.   NATURE NEUROSCIENCE

Hepcidin Is Involved in Iron Regulation in the Ischemic Brain

(2011) Hui Ding et al.   PLoS One

The overlap between neurodegenerative and vascular factors in the pathogenesis of dementia

(2010) Costantino Iadecola   ACTA NEUROPATHOLOGICA

Iron-Export Ferroxidase Activity of β-Amyloid Precursor Protein Is Inhibited by Zinc in Alzheimer's Disease

(2010) James A. Duce et al.   CELL

Two to Tango: Regulation of Mammalian Iron Metabolism

(2010) Matthias W. Hentze et al.   CELL

Hepcidin expression in anemia of chronic disease and concomitant iron-deficiency anemia

(2010) Pan-pan Cheng et al.   CLINICAL AND EXPERIMENTAL MEDICINE

Hereditary Hemochromatosis: Pathogenesis, Diagnosis, and Treatment

(2010) Antonello Pietrangelo   GASTROENTEROLOGY

Increased BMP6 Levels in the Brains of Alzheimer's Disease Patients and APP Transgenic Mice Are Accompanied by Impaired Neurogenesis

(2010) L. Crews et al.   JOURNAL OF NEUROSCIENCE

Loss of human Greatwall results in G2 arrest and multiple mitotic defects due to deregulation of the cyclin B-Cdc2/PP2A balance

(2010) Andrew Burgess et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inflammation in Alzheimer's disease: relevance to pathogenesis and therapy

(2010) Elina Zotova et al.   Alzheimers Research & Therapy

Role of hepcidin in murine brain iron metabolism

(2009) S.-M. Wang et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Astrocytes and oligodendrocytes can be generated from NG2+progenitors after acute brain injury: intracellular localization of oligodendrocyte transcription factor 2 is associated with their fate choice

(2009) Jing-Wei Zhao et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Combined deletion of Hfe and transferrin receptor 2 in mice leads to marked dysregulation of hepcidin and iron overload

(2009) Daniel F. Wallace et al.   HEPATOLOGY

Development of a method for the sensitive and quantitative determination of hepcidin in human serum using LC-MS/MS

(2009) Hongyan Li et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Apolipoprotein E, an important player in longevity and age-related diseases

(2008) Lisa S. Ang et al.   EXPERIMENTAL GERONTOLOGY

apoE isoform–specific disruption of amyloid β peptide clearance from mouse brain

(2008) Rashid Deane et al.   JOURNAL OF CLINICAL INVESTIGATION

Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

(2008) Ganesh M Shankar et al.   NATURE MEDICINE

The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders

(2008) Berislav V. Zlokovic   NEURON