Role of Vitamin E in the Treatment of Alzheimer’s Disease: Evidence from Animal Models

Vitamin E: Emerging aspects and new directions

(2017) Francesco Galli et al.   FREE RADICAL BIOLOGY AND MEDICINE

Do low-serum vitamin E levels increase the risk of Alzheimer disease in older people? Evidence from a meta-analysis of case-control studies

(2017) Yonghai Dong et al.   INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY

Clinical practice with anti-dementia drugs: A revised (third) consensus statement from the British Association for Psychopharmacology

(2017) John T O’Brien et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Plaque formation and the intraneuronal accumulation of β-amyloid in Alzheimer's disease

(2017) Reisuke H. Takahashi et al.   PATHOLOGY INTERNATIONAL

Association of Antioxidant Supplement Use and Dementia in the Prevention of Alzheimer’s Disease by Vitamin E and Selenium Trial (PREADViSE)

(2017) Richard J. Kryscio et al.   JAMA Neurology

Vitamin E Paradox in Alzheimer's Disease: It Does Not Prevent Loss of Cognition and May Even Be Detrimental

(2017) Ana Lloret et al.   JOURNAL OF ALZHEIMERS DISEASE

High Plasma Levels of Vitamin E Forms and Reduced Alzheimer's Disease Risk in Advanced Age

(2017) Francesca Mangialasche et al.   JOURNAL OF ALZHEIMERS DISEASE

Use of Vitamin E and C Supplements for the Prevention of Cognitive Decline

(2016) Luta Luse Basambombo et al.   ANNALS OF PHARMACOTHERAPY

Alpha-tocopherol quinine ameliorates spatial memory deficits by reducing beta-amyloid oligomers, neuroinflammation and oxidative stress in transgenic mice with Alzheimer's disease

(2016) Shao-wei Wang et al.   BEHAVIOURAL BRAIN RESEARCH

Tocotrienol-Rich Fraction Modulates Amyloid Pathology and Improves Cognitive Function in AβPP/PS1 Mice

(2016) Nor Faeizah Ibrahim et al.   JOURNAL OF ALZHEIMERS DISEASE

Multiple mechanisms of age-dependent accumulation of amyloid beta protein in rat brain: Prevention by dietary supplementation with N-acetylcysteine, α-lipoic acid and α-tocopherol

(2016) Maitrayee Sinha et al.   NEUROCHEMISTRY INTERNATIONAL

Brain tocopherols related to Alzheimer's disease neuropathology in humans

(2015) Martha Clare Morris et al.   Alzheimers & Dementia

Long-Term Vitamin E-Deficient Mice Exhibit Cognitive Dysfunction via Elevation of Brain Oxidation

(2015) Koji FUKUI et al.   JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY

Vitamin E and neurodegeneration

(2015) Lynn M. Ulatowski et al.   NEUROBIOLOGY OF DISEASE

Alzheimer's disease

(2015) Colin L. Masters et al.   Nature Reviews Disease Primers

Natural forms of vitamin E: metabolism, antioxidant, and anti-inflammatory activities and their role in disease prevention and therapy

(2014) Qing Jiang   FREE RADICAL BIOLOGY AND MEDICINE

Tau Protein Modifications and Interactions: Their Role in Function and Dysfunction

(2014) Anna Mietelska-Porowska et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Effect of Vitamin E and Memantine on Functional Decline in Alzheimer Disease

(2014) Maurice W. Dysken et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Amyloid-Beta: A Crucial Factor in Alzheimer's Disease

(2014) Saeed Sadigh-Eteghad et al.   MEDICAL PRINCIPLES AND PRACTICE

Models of β-amyloid induced Tau-pathology: the long and “folded” road to understand the mechanism

(2014) Ilie-Cosmin Stancu et al.   Molecular Neurodegeneration

Amyloid-β and Tau

(2014) George S. Bloom   JAMA Neurology

Aβ and tau toxicities in Alzheimer’s are linked via oxidative stress-induced p38 activation: Protective role of vitamin E

(2014) E. Giraldo et al.   Redox Biology

Abeta, oxidative stress in Alzheimer disease: Evidence based on proteomics studies

(2013) Aaron M. Swomley et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Combination of N-acetylcysteine, α-lipoic acid and α-tocopherol substantially prevents the brain synaptosomal alterations and memory and learning deficits of aged rats

(2013) Ishita Guha Thakurta et al.   EXPERIMENTAL GERONTOLOGY

The amyloid precursor protein: A biochemical enigma in brain development, function and disease

(2013) Natalia N. Nalivaeva et al.   FEBS LETTERS

Role of vitamin E as a lipid-soluble peroxyl radical scavenger: in vitro and in vivo evidence

(2013) Etsuo Niki   FREE RADICAL BIOLOGY AND MEDICINE

Involvement of brain oxidation in the cognitive impairment in a triple transgenic mouse model of Alzheimer's disease: Noninvasive measurement of the brain redox state by magnetic resonance imaging

(2013) Y. Ishihara et al.   FREE RADICAL RESEARCH

Amyloid- 1-42 Slows Clearance of Synaptically Released Glutamate by Mislocalizing Astrocytic GLT-1

(2013) A. Scimemi et al.   JOURNAL OF NEUROSCIENCE

Increased Amyloid-β Peptide-Induced Memory Deficits in Phospholipid Transfer Protein (PLTP) Gene Knockout Mice

(2013) Catherine Desrumaux et al.   NEUROPSYCHOPHARMACOLOGY

Vitamin E is essential for Purkinje neuron integrity

(2013) L. Ulatowski et al.   NEUROSCIENCE

Oxidative Stress and the Pathogenesis of Alzheimer's Disease

(2013) Yan Zhao et al.   Oxidative Medicine and Cellular Longevity

The Genetics of Alzheimer Disease

(2013) R. E. Tanzi   Cold Spring Harbor Perspectives in Medicine

The Clinical Problem of Symptomatic Alzheimer Disease and Mild Cognitive Impairment

(2013) R. Tarawneh et al.   Cold Spring Harbor Perspectives in Medicine

Mitochondrion-Derived Reactive Oxygen Species Lead to Enhanced Amyloid Beta Formation

(2012) Kristina Leuner et al.   ANTIOXIDANTS & REDOX SIGNALING

Amyloid β-Peptide (1–42)-Induced Oxidative Stress in Alzheimer Disease: Importance in Disease Pathogenesis and Progression

(2012) D. Allan Butterfield et al.   ANTIOXIDANTS & REDOX SIGNALING

Dietary supplementation with N-acetyl cysteine, α-tocopherol and α-lipoic acid reduces the extent of oxidative stress and proinflammatory state in aged rat brain

(2012) Ishita Guha Thakurta et al.   BIOGERONTOLOGY

Tocotrienol research: past into present

(2012) Rebecca SY Wong et al.   NUTRITION REVIEWS

Dietary Antioxidants and Long-term Risk of Dementia

(2010) Elizabeth E. Devore et al.   ARCHIVES OF NEUROLOGY

Alpha-tocopherol quinone inhibits beta-amyloid aggregation and cytotoxicity, disaggregates preformed fibrils and decreases the production of reactive oxygen species, NO and inflammatory cytokines

(2010) Shi-gao Yang et al.   NEUROCHEMISTRY INTERNATIONAL

Ataxia with vitamin E deficiency: update of molecular diagnosis

(2010) I. Di Donato et al.   NEUROLOGICAL SCIENCES

Vitamin E Use Is Associated with Improved Survival in an Alzheimer’s Disease Cohort

(2009) Valory N. Pavlik et al.   DEMENTIA AND GERIATRIC COGNITIVE DISORDERS

Depletion of Vitamin E Increases Amyloid β Accumulation by Decreasing Its Clearances from Brain and Blood in a Mouse Model of Alzheimer Disease

(2009) Yoichiro Nishida et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The role of α-tocopherol in motor hypofunction with aging in α-tocopherol transfer protein knockout mice as assessed by oxidative stress biomarkers

(2009) Yasukazu Yoshida et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Soluble fibrillar oligomer levels are elevated in Alzheimer's disease brain and correlate with cognitive dysfunction

(2009) Jennifer L. Tomic et al.   NEUROBIOLOGY OF DISEASE

Antioxidants and cognitive training interact to affect oxidative stress and memory in APP/PSEN1 mice

(2009) F.E. Harrison et al.   NUTRITIONAL NEUROSCIENCE

Chronic treatment with tocotrienol, an isoform of vitamin E, prevents intracerebroventricular streptozotocin-induced cognitive impairment and oxidative–nitrosative stress in rats

(2009) Vinod Tiwari et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Brain oxidative stress in a triple-transgenic mouse model of Alzheimer disease

(2008) Rosa Resende et al.   FREE RADICAL BIOLOGY AND MEDICINE

Amyloid β-Protein Toxicity and the Pathogenesis of Alzheimer Disease

(2008) Bruce A. Yankner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Alzheimer's disease-type neuronal tau hyperphosphorylation induced by Aβ oligomers

(2007) Fernanda G. De Felice et al.   NEUROBIOLOGY OF AGING