Liaisons dangereuses: Intrinsic Disorder in Cellular Proteins Recruited to Viral Infection-Related Biocondensates

Prediction of liquid–liquid phase separating proteins using machine learning

(2022) Xiaoquan Chu et al.   BMC BIOINFORMATICS

Birnaviridae virus factories show features of liquid-liquid phase separation, and are distinct from paracrystalline arrays of virions observed by electron microscopy

(2022) Vishwanatha R. A. P. Reddy et al.   JOURNAL OF VIROLOGY

Liquid–liquid phase separation as an organizing principle of intracellular space: overview of the evolution of the cell compartmentalization concept

(2022) Iuliia A. Antifeeva et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The roles of G3BP1 in human diseases (review)

(2022) Yidong Ge et al.   GENE

BIAPSS: A Comprehensive Physicochemical Analyzer of Proteins Undergoing Liquid–Liquid Phase Separation

(2022) Aleksandra E. Badaczewska-Dawid et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

FuzDrop on AlphaFold: visualizing the sequence-dependent propensity of liquid–liquid phase separation and aggregation of proteins

(2022) Andras Hatos et al.   NUCLEIC ACIDS RESEARCH

Herpesvirus Replication Compartments: Dynamic Biomolecular Condensates?

(2022) Enrico Caragliano et al.   Viruses-Basel

Human Metapneumovirus Phosphoprotein Independently Drives Phase Separation and Recruits Nucleoprotein to Liquid-Like Bodies

(2022) Kerri Beth Boggs et al.   mBio

Recent progress on FAK inhibitors with dual targeting capabilities for cancer treatment

(2022) Xianbo Wu et al.   BIOMEDICINE & PHARMACOTHERAPY

Phase separation in viral infections

(2022) Haohua Li et al.   TRENDS IN MICROBIOLOGY

Liquid Phase Partitioning in Virus Replication: Observations and Opportunities

(2022) Chao Wu et al.   Annual Review of Virology

When liquid-liquid phase separation meets viral infections

(2022) Wenqiang Wei et al.   Frontiers in Immunology

Liquid–liquid phase separation mediates the formation of herpesvirus assembly compartments

(2022) Sheng Zhou et al.   JOURNAL OF CELL BIOLOGY

Intrinsic protein disorder and conditional folding in AlphaFoldDB

(2022) Damiano Piovesan et al.   PROTEIN SCIENCE

Scaffolding viral protein NC nucleates phase separation of the HIV-1 biomolecular condensate

(2022) Anne Monette et al.   Cell Reports

Biomolecular Condensation of the Human Papillomavirus E2 Master Regulator with p53: Implications in Viral Replication

(2022) Silvia Susana Borkosky et al.   JOURNAL OF MOLECULAR BIOLOGY

Rapid prediction and analysis of protein intrinsic disorder

(2022) Guy W. Dayhoff et al.   PROTEIN SCIENCE

Arg/Lys-containing IDRs are cryptic binding domains for ATP and nucleic acids that interplay to modulate LLPS

(2022) Mei Dang et al.   Communications Biology

Formation and Function of Liquid-Like Viral Factories in Negative-Sense Single-Stranded RNA Virus Infections

(2021) Justin M. Su et al.   Viruses-Basel

MDA5 Governs the Innate Immune Response to SARS-CoV-2 in Lung Epithelial Cells

(2021) Xin Yin et al.   Cell Reports

Recent Developments in the Field of Intrinsically Disordered Proteins: Intrinsic Disorder–Based Emergence in Cellular Biology in Light of the Physiological and Pathological Liquid–Liquid Phase Transitions

(2021) Vladimir N. Uversky   Annual Review of Biophysics

SARS-CoV-2 triggers an MDA-5-dependent interferon response which is unable to control replication in lung epithelial cells

(2021) Antoine Rebendenne et al.   JOURNAL OF VIROLOGY

Biomolecular condensates at the nexus of cellular stress, protein aggregation disease and ageing

(2021) Simon Alberti et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Liquid Biomolecular Condensates and Viral Lifecycles: Review and Perspectives

(2021) Temitope Etibor et al.   Viruses-Basel

Herpes Simplex Virus and Pattern Recognition Receptors: An Arms Race

(2021) Jun Zhao et al.   Frontiers in Immunology

Integration of Data from Liquid–Liquid Phase Separation Databases Highlights Concentration and Dosage Sensitivity of LLPS Drivers

(2021) Nazanin Farahi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The HSV-1 Transcription Factor ICP4 Confers Liquid-Like Properties to Viral Replication Compartments

(2021) Michael Seyffert et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Critical assessment of protein intrinsic disorder prediction

(2021) Marco Necci et al.   NATURE METHODS

Mol* Viewer: modern web app for 3D visualization and analysis of large biomolecular structures

(2021) David Sehnal et al.   NUCLEIC ACIDS RESEARCH

Membraneless organelles restructured and built by pandemic viruses: HIV-1 and SARS-CoV-2

(2021) Viviana Scoca et al.   Journal of Molecular Cell Biology

The SARS-CoV-2 nucleocapsid protein is dynamic, disordered, and phase separates with RNA

(2021) Jasmine Cubuk et al.   Nature Communications

ISG15-dependent activation of the sensor MDA5 is antagonized by the SARS-CoV-2 papain-like protease to evade host innate immunity

(2021) GuanQun Liu et al.   Nature Microbiology

Liquid–liquid phase separation underpins the formation of replication factories in rotaviruses

(2021) Florian Geiger et al.   EMBO JOURNAL

Dengue and Zika virus capsid proteins bind to membranes and self-assemble into liquid droplets with nucleic acids

(2021) Ernesto E. Ambroggio et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sequence Determinants of the Aggregation of Proteins Within Condensates Generated by Liquid-liquid Phase Separation

(2021) Michele Vendruscolo et al.   JOURNAL OF MOLECULAR BIOLOGY

AlphaFold and Implications for Intrinsically Disordered Proteins

(2021) Kiersten M. Ruff et al.   JOURNAL OF MOLECULAR BIOLOGY

A condensate-hardening drug blocks RSV replication in vivo

(2021) Jennifer Risso-Ballester et al.   NATURE

Highly accurate protein structure prediction with AlphaFold

(2021) John Jumper et al.   NATURE

Targeting liquid–liquid phase separation of SARS-CoV-2 nucleocapsid protein promotes innate antiviral immunity by elevating MAVS activity

(2021) Shuai Wang et al.   NATURE CELL BIOLOGY

Deciphering CAD : Structure and function of a mega‐enzymatic pyrimidine factory in health and disease

(2021) Francisco Caño‐Ochoa et al.   PROTEIN SCIENCE

How Do Flaviviruses Hijack Host Cell Functions by Phase Separation?

(2021) Akatsuki Saito et al.   Viruses-Basel

Viroplasms: Assembly and Functions of Rotavirus Replication Factories

(2021) Guido Papa et al.   Viruses-Basel

Research Progress on the Structure and Function of G3BP

(2021) Weifang Kang et al.   Frontiers in Immunology

New Perspectives on the Biogenesis of Viral Inclusion Bodies in Negative-Sense RNA Virus Infections

(2021) Olga Dolnik et al.   Cells

Liquid-liquid phase separation as a common organizing principle of intracellular space and biomembranes providing dynamic adaptive responses

(2021) Semen V. Nesterov et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Borna disease virus phosphoprotein triggers the organization of viral inclusion bodies by liquid-liquid phase separation

(2021) Yuya Hirai et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Interferon responses to norovirus infections: current and future perspectives

(2021) Aminu S. Jahun et al.   JOURNAL OF GENERAL VIROLOGY

AlphaFold Protein Structure Database: massively expanding the structural coverage of protein-sequence space with high-accuracy models

(2021) Mihaly Varadi et al.   NUCLEIC ACIDS RESEARCH

DisProt in 2022: improved quality and accessibility of protein intrinsic disorder annotation

(2021) Federica Quaglia et al.   NUCLEIC ACIDS RESEARCH

The HIV-1 Nucleocapsid Regulates Its Own Condensation by Phase-Separated Activity-Enhancing Sequestration of the Viral Protease during Maturation

(2021) Sébastien Lyonnais et al.   Viruses-Basel

Determinants for intrinsically disordered protein recruitment into phase-separated protein condensates

(2021) Yongsang Jo et al.   Chemical Science

Deconstructing virus condensation

(2021) Nora Lopez et al.   PLoS Pathogens

SARS-CoV-2 nucleocapsid protein binds host mRNAs and attenuates stress granules to impair host stress response

(2021) Syed Nabeel-Shah et al.   iScience

P53 and The Immune Response: 40 Years of Exploration—A Plan for the Future

(2020) Arnold J. Levine   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Can phase separation buffer cellular noise?

(2020) Joshua A. Riback et al.   SCIENCE

Valence and patterning of aromatic residues determine the phase behavior of prion-like domains

(2020) Erik W. Martin et al.   SCIENCE

Competing Protein-RNA Interaction Networks Control Multiphase Intracellular Organization

(2020) David W. Sanders et al.   CELL

NOD1 Promotes Antiviral Signaling by Binding Viral RNA and Regulating the Interaction of MDA5 and MAVS

(2020) Xiao Man Wu et al.   JOURNAL OF IMMUNOLOGY

Measles virus nucleo- and phosphoproteins form liquid-like phase-separated compartments that promote nucleocapsid assembly

(2020) Serafima Guseva et al.   Science Advances

The Cellular Protein CAD is Recruited into Ebola Virus Inclusion Bodies by the Nucleoprotein NP to Facilitate Genome Replication and Transcription

(2020) Janine Brandt et al.   Cells

Liquid–liquid phase separation by SARS-CoV-2 nucleocapsid protein and RNA

(2020) Hui Chen et al.   CELL RESEARCH

Respiratory Syncytial Virus Sequesters NF-κB Subunit p65 to Cytoplasmic Inclusion Bodies To Inhibit Innate Immune Signaling

(2020) Fatoumatta Jobe et al.   JOURNAL OF VIROLOGY

Expansion of Intrinsically Disordered Proteins Increases the Range of Stability of Liquid–Liquid Phase Separation

(2020) Adiran Garaizar et al.   MOLECULES

Minimal Elements Required for the Formation of Respiratory Syncytial Virus Cytoplasmic Inclusion Bodies In Vivo and In Vitro

(2020) Marie Galloux et al.   mBio

Molecular mechanisms of stress granule assembly and disassembly

(2020) Sarah Hofmann et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Negri bodies and other virus membrane-less replication compartments

(2020) Quentin Nevers et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

MobiDB-lite 3.0: fast consensus annotation of intrinsic disorder flavors in proteins

(2020) Marco Necci et al.   BIOINFORMATICS

SARS‐CoV‐2 nucleocapsid protein phase‐separates with RNA and with human hnRNPs

(2020) Theodora Myrto Perdikari et al.   EMBO JOURNAL

Liquid–Liquid Phase Separation by Intrinsically Disordered Protein Regions of Viruses: Roles in Viral Life Cycle and Control of Virus–Host Interactions

(2020) Stefania Brocca et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Phosphoregulation of Phase Separation by the SARS-CoV-2 N Protein Suggests a Biophysical Basis for its Dual Functions

(2020) Christopher R. Carlson et al.   MOLECULAR CELL

UniProt: the universal protein knowledgebase in 2021

(2020) et al.   NUCLEIC ACIDS RESEARCH

Widespread occurrence of the droplet state of proteins in the human proteome

(2020) Maarten Hardenberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nucleocapsid protein of SARS-CoV-2 phase separates into RNA-rich polymerase-containing condensates

(2020) Adriana Savastano et al.   Nature Communications

MAPKAPK2: the master regulator of RNA-binding proteins modulates transcript stability and tumor progression

(2019) Sourabh Soni et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

The nucleolus functions as a phase-separated protein quality control compartment

(2019) F. Frottin et al.   SCIENCE

Influenza A virus ribonucleoproteins form liquid organelles at endoplasmic reticulum exit sites

(2019) Marta Alenquer et al.   Nature Communications

Measles Virus Forms Inclusion Bodies with Properties of Liquid Organelles

(2019) Yuqin Zhou et al.   JOURNAL OF VIROLOGY

Formation of adenovirus DNA replication compartments

(2019) Paloma Hidalgo et al.   FEBS LETTERS

PhaSepDB: a database of liquid–liquid phase separation related proteins

(2019) Kaiqiang You et al.   NUCLEIC ACIDS RESEARCH

Strategies for Success. Viral Infections and Membraneless Organelles

(2019) Aracelly Gaete-Argel et al.   Frontiers in Cellular and Infection Microbiology

IUPred2A: context-dependent prediction of protein disorder as a function of redox state and protein binding

(2018) Bálint Mészáros et al.   NUCLEIC ACIDS RESEARCH

Protein Phase Separation: A New Phase in Cell Biology

(2018) Steven Boeynaems et al.   TRENDS IN CELL BIOLOGY

RSV hijacks cellular protein phosphatase 1 to regulate M2-1 phosphorylation and viral transcription

(2018) Charles-Adrien Richard et al.   PLoS Pathogens

Intrinsic Disorder and Posttranslational Modifications: The Darker Side of the Biological Dark Matter

(2018) April L. Darling et al.   Frontiers in Genetics

Inhibiting pyrimidine biosynthesis impairs Ebola virus replication through depletion of nucleoside pools and activation of innate immune responses

(2018) Priya Luthra et al.   ANTIVIRAL RESEARCH

The molecular language of membraneless organelles

(2018) Edward Gomes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The roles and mechanisms of G3BP1 in tumour promotion

(2018) Cong-Hui Zhang et al.   JOURNAL OF DRUG TARGETING

Who's In and Who's Out—Compositional Control of Biomolecular Condensates

(2018) Jonathon A. Ditlev et al.   JOURNAL OF MOLECULAR BIOLOGY

Phase Transitions Drive the Formation of Vesicular Stomatitis Virus Replication Compartments

(2018) Bianca S. Heinrich et al.   mBio

Controllable protein phase separation and modular recruitment to form responsive membraneless organelles

(2018) Benjamin S. Schuster et al.   Nature Communications

A genome-wide siRNA screen identifies a druggable host pathway essential for the Ebola virus life cycle

(2018) Scott Martin et al.   Genome Medicine

Phosphatidylinositide 3-Kinase Contributes to the Anti-Inflammatory Effect of Abutilon crispum L. Medik Methanol Extract

(2018) Stephanie Triseptya Hunto et al.   Evidence-based Complementary and Alternative Medicine

G3BP1 promotes DNA binding and activation of cGAS

(2018) Zhao-Shan Liu et al.   NATURE IMMUNOLOGY

Modulation of the transcription factor NF-κB in antigen-presenting cells by bovine respiratory syncytial virus small hydrophobic protein

(2017) Nicola Pollock et al.   JOURNAL OF GENERAL VIROLOGY

Human Metapneumovirus Induces Formation of Inclusion Bodies for Efficient Genome Replication and Transcription

(2017) Nicolás Cifuentes-Muñoz et al.   JOURNAL OF VIROLOGY

Biomolecular condensates: organizers of cellular biochemistry

(2017) Salman F. Banani et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Structural characterization of interactions between transactivation domain 1 of the p65 subunit of NF-κB and transcription regulatory factors

(2017) Lauriane Lecoq et al.   NUCLEIC ACIDS RESEARCH

Liquid phase condensation in cell physiology and disease

(2017) Yongdae Shin et al.   SCIENCE

Ebola virus VP35 blocks stress granule assembly

(2017) Valerie Le Sage et al.   VIROLOGY

The stress granule component G3BP is a novel interaction partner for the nuclear shuttle proteins of the nanovirus pea necrotic yellow dwarf virus and geminivirus abutilon mosaic virus

(2017) Susanna Krapp et al.   VIRUS RESEARCH

Negri bodies are viral factories with properties of liquid organelles

(2017) Jovan Nikolic et al.   Nature Communications

Functional organization of cytoplasmic inclusion bodies in cells infected by respiratory syncytial virus

(2017) Vincent Rincheval et al.   Nature Communications

Influenza virus genome reaches the plasma membrane via a modified endoplasmic reticulum and Rab11-dependent vesicles

(2017) Isabel Fernández de Castro Martin et al.   Nature Communications

ALS mutant SOD1 interacts with G3BP1 and affects stress granule dynamics

(2016) Jozsef Gal et al.   ACTA NEUROPATHOLOGICA

Mechanisms of FUS mutations in familial amyotrophic lateral sclerosis

(2016) Yulei Shang et al.   BRAIN RESEARCH

Compositional Control of Phase-Separated Cellular Bodies

(2016) Salman F. Banani et al.   CELL

Intrinsic disorder in proteins involved in amyotrophic lateral sclerosis

(2016) Nikolas Santamaria et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The hnRNP family: insights into their role in health and disease

(2016) Thomas Geuens et al.   HUMAN GENETICS

p53 Proteoforms and Intrinsic Disorder: An Illustration of the Protein Structure–Function Continuum Concept

(2016) Vladimir Uversky   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Ebola Virus Does Not Induce Stress Granule Formation during Infection and Sequesters Stress Granule Proteins within Viral Inclusions

(2016) Emily V. Nelson et al.   JOURNAL OF VIROLOGY

DisProt 7.0: a major update of the database of disordered proteins

(2016) Damiano Piovesan et al.   NUCLEIC ACIDS RESEARCH

Rabies Virus Infection Induces the Formation of Stress Granules Closely Connected to the Viral Factories

(2016) Jovan Nikolic et al.   PLoS Pathogens

ALS mutations in TLS/FUS disrupt target gene expression

(2015) Tristan H. Coady et al.   GENES & DEVELOPMENT

The role of TDP-43 in the pathogenesis of ALS and FTLD: Figure 1

(2015) Marco Baralle et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Improving protein order-disorder classification using charge-hydropathy plots

(2015) Fei Huang et al.   BMC BIOINFORMATICS

Targeting FAK in human cancer: from finding to first clinical trials

(2014) Vita Golubovskaya   Frontiers in Bioscience-Landmark

ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects

(2014) Haiyan Qiu et al.   JOURNAL OF CLINICAL INVESTIGATION

Recombinant bovine respiratory syncytial virus with deletion of the SH gene induces increased apoptosis and pro-inflammatory cytokines in vitro, and is attenuated and induces protective immunity in calves

(2014) G. Taylor et al.   JOURNAL OF GENERAL VIROLOGY

Focal Adhesion Kinase Is Involved in Rabies Virus Infection through Its Interaction with Viral Phosphoprotein P

(2014) Baptiste Fouquet et al.   JOURNAL OF VIROLOGY

The role of FUS gene variants in neurodegenerative diseases

(2014) Hao Deng et al.   Nature Reviews Neurology

The interferon response to intracellular DNA: Why so many receptors?

(2013) Leonie Unterholzner   IMMUNOBIOLOGY

The RNA-binding Protein Fused in Sarcoma (FUS) Functions Downstream of Poly(ADP-ribose) Polymerase (PARP) in Response to DNA Damage

(2013) Adam S. Mastrocola et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS

(2013) Hong Joo Kim et al.   NATURE

Diversion of stress granules and P-bodies during viral infection

(2013) Lucas C. Reineke et al.   VIROLOGY

Regulation of protein phosphatase 1 by intrinsically disordered proteins

(2012) Meng S. Choy et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Cell-free Formation of RNA Granules: Bound RNAs Identify Features and Components of Cellular Assemblies

(2012) Tina W. Han et al.   CELL

Both G3BP1 and G3BP2 contribute to stress granule formation

(2012) Hideaki Matsuki et al.   GENES TO CELLS

RNA-binding ability of FUS regulates neurodegeneration, cytoplasmic mislocalization and incorporation into stress granules associated with FUS carrying ALS-linked mutations

(2012) J. G. Daigle et al.   HUMAN MOLECULAR GENETICS

Ndfip1 Negatively Regulates RIG-I-Dependent Immune Signaling by Enhancing E3 Ligase Smurf1-Mediated MAVS Degradation

(2012) Y. Wang et al.   JOURNAL OF IMMUNOLOGY

p38 and OGT Sequestration into Viral Inclusion Bodies in Cells Infected with Human Respiratory Syncytial Virus Suppresses MK2 Activities and Stress Granule Assembly

(2012) Jens Fricke et al.   JOURNAL OF VIROLOGY

Hsp70 Protein Positively Regulates Rabies Virus Infection

(2012) X. Lahaye et al.   JOURNAL OF VIROLOGY

Human Respiratory Syncytial Virus Nucleoprotein and Inclusion Bodies Antagonize the Innate Immune Response Mediated by MDA5 and MAVS

(2012) A. W. Lifland et al.   JOURNAL OF VIROLOGY

Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs

(2012) Clotilde Lagier-Tourenne et al.   NATURE NEUROSCIENCE

D2P2: database of disordered protein predictions

(2012) Matt E. Oates et al.   NUCLEIC ACIDS RESEARCH

TLS/FUS (translocated in liposarcoma/fused in sarcoma) regulates target gene transcription via single-stranded DNA response elements

(2012) A. Y. Tan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of stress granules in virus systems

(2012) James P. White et al.   TRENDS IN MICROBIOLOGY

How Do Viruses Interact with Stress-Associated RNA Granules?

(2012) Richard E. Lloyd   PLoS Pathogens

ESpritz: accurate and fast prediction of protein disorder

(2011) Ian Walsh et al.   BIOINFORMATICS

Distinct p53 Transcriptional Programs Dictate Acute DNA-Damage Responses and Tumor Suppression

(2011) Colleen A. Brady et al.   CELL

A majority of the cancer/testis antigens are intrinsically disordered proteins

(2011) Krithika Rajagopalan et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Characterizing the RNA targets and position-dependent splicing regulation by TDP-43

(2011) James R Tollervey et al.   NATURE NEUROSCIENCE

PhosphoSitePlus: a comprehensive resource for investigating the structure and function of experimentally determined post-translational modifications in man and mouse

(2011) P. V. Hornbeck et al.   NUCLEIC ACIDS RESEARCH

Heat Shock Protein 70 Inhibits the Activity of Influenza A Virus Ribonucleoprotein and Blocks the Replication of Virus In Vitro and In Vivo

(2011) Gang Li et al.   PLoS One

Emerging picture of host chaperone and cyclophilin roles in RNA virus replication

(2011) P.D. Nagy et al.   VIROLOGY

Thousands of Rab GTPases for the Cell Biologist

(2011) Yoan Diekmann et al.   PLoS Computational Biology

TDP-43 pathology in sporadic ALS occurs in motor neurons lacking the RNA editing enzyme ADAR2

(2010) Hitoshi Aizawa et al.   ACTA NEUROPATHOLOGICA

PONDR-FIT: A meta-predictor of intrinsically disordered amino acids

(2010) Bin Xue et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

MOBI: a web server to define and visualize structural mobility in NMR protein ensembles

(2010) A. J. M. Martin et al.   BIOINFORMATICS

Peroxisomes Are Signaling Platforms for Antiviral Innate Immunity

(2010) Evelyn Dixit et al.   CELL

ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import

(2010) Dorothee Dormann et al.   EMBO JOURNAL

DEAD/H BOX 3 (DDX3) helicase binds the RIG-I adaptor IPS-1 to up-regulate IFN-β-inducing potential

(2010) Hiroyuki Oshiumi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Cellular functions of FAK kinases: insight into molecular mechanisms and novel functions

(2010) M. D. Schaller   JOURNAL OF CELL SCIENCE

Respiratory Syncytial Virus-Mediated NF- B p65 Phosphorylation at Serine 536 Is Dependent on RIG-I, TRAF6, and IKK 

(2010) F. Yoboua et al.   JOURNAL OF VIROLOGY

Gymnastics of Molecular Chaperones

(2010) Matthias P. Mayer   MOLECULAR CELL

SUPERFAMILY 1.75 including a domain-centric gene ontology method

(2010) D. A. de Lima Morais et al.   NUCLEIC ACIDS RESEARCH

The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored

(2010) D. Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Tar DNA Binding Protein-43 (TDP-43) Associates with Stress Granules: Analysis of Cultured Cells and Pathological Brain Tissue

(2010) Liqun Liu-Yesucevitz et al.   PLoS One

Hepatitis C Virus Core Protein Abrogates the DDX3 Function That Enhances IPS-1-Mediated IFN–Beta Induction

(2010) Hiroyuki Oshiumi et al.   PLoS One

The extended PP1 toolkit: designed to create specificity

(2010) Mathieu Bollen et al.   TRENDS IN BIOCHEMICAL SCIENCES

The role of posttranslational modifications in the assembly of stress granules

(2010) Takbum Ohn et al.   Wiley Interdisciplinary Reviews-RNA

Induction of type I interferon by RNA viruses: cellular receptors and their substrates

(2009) Alina Baum et al.   AMINO ACIDS

ANCHOR: web server for predicting protein binding regions in disordered proteins

(2009) Z. Dosztanyi et al.   BIOINFORMATICS

RNA Polymerase III Detects Cytosolic DNA and Induces Type I Interferons through the RIG-I Pathway

(2009) Yu-Hsin Chiu et al.   CELL

Predicting intrinsic disorder in proteins: an overview

(2009) Bo He et al.   CELL RESEARCH

Pathogen Recognition and Inflammatory Signaling in Innate Immune Defenses

(2009) T. H. Mogensen   CLINICAL MICROBIOLOGY REVIEWS

CDF it all: Consensus prediction of intrinsically disordered proteins based on various cumulative distribution functions

(2009) Bin Xue et al.   FEBS LETTERS

Rotavirus and Reovirus Modulation of the Interferon Response

(2009) Barbara Sherry   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Global Analysis of TDP-43 Interacting Proteins Reveals Strong Association with RNA Splicing and Translation Machinery

(2009) Brian D. Freibaum et al.   JOURNAL OF PROTEOME RESEARCH

A Targeted Analysis of Cellular Chaperones Reveals Contrasting Roles for Heat Shock Protein 70 in Flock House Virus RNA Replication

(2009) S. A. Weeks et al.   JOURNAL OF VIROLOGY

Functional Characterization of Negri Bodies (NBs) in Rabies Virus-Infected Cells: Evidence that NBs Are Sites of Viral Transcription and Replication

(2009) X. Lahaye et al.   JOURNAL OF VIROLOGY

Prediction of Protein Binding Regions in Disordered Proteins

(2009) Bálint Mészáros et al.   PLoS Computational Biology

Structural Biology of the Tumor Suppressor p53

(2008) Andreas C. Joerger et al.   Annual Review of Biochemistry

Protective effect of a RSV subunit vaccine candidate G1F/M2 was enhanced by a HSP70-Like protein in mice

(2008) Ruihong Zeng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

MeDor: a metaserver for predicting protein disorder

(2008) Philippe Lieutaud et al.   BMC GENOMICS

Nuclear functions of heterogeneous nuclear ribonucleoproteins A/B

(2008) Yaowu He et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid–inducible gene-I and melanoma differentiation–associated gene 5

(2008) Hiroki Kato et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A Plant Virus Movement Protein Forms Ringlike Complexes with the Major Nucleolar Protein, Fibrillarin, In Vitro

(2008) Elisabetta Canetta et al.   JOURNAL OF MOLECULAR BIOLOGY

Intrinsic disorder in pathogenic and non-pathogenic microbes: discovering and analyzing the unfoldomes of early-branching eukaryotes

(2008) Amrita Mohan et al.   Molecular BioSystems

A functional RNAi screen links O-GlcNAc modification of ribosomal proteins to stress granule and processing body assembly

(2008) Takbum Ohn et al.   NATURE CELL BIOLOGY

TOP-IDP-Scale: A New Amino Acid Scale Measuring Propensity for Intrinsic Disorder

(2008) Andrew Campen et al.   PROTEIN AND PEPTIDE LETTERS