A genome-wide siRNA screen identifies a druggable host pathway essential for the Ebola virus life cycle

Title
A genome-wide siRNA screen identifies a druggable host pathway essential for the Ebola virus life cycle
Authors
Keywords
Ebola virus, Carbamoyl phosphate synthetase 2 aspartate transcarbamylase and dihydroorotase, De novo pyrimidine synthesis, Dihydroorotate dehydrogenase, Host factor, Teriflunomide, siRNA screen, Non-segmented negative-sense RNA viruses, NNSV
Journal
Genome Medicine
Volume 10, Issue 1, Pages -
Publisher
Springer Nature
Online
2018-07-27
DOI
10.1186/s13073-018-0570-1

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