Negri bodies and other virus membrane-less replication compartments

Phase separation of Epstein-Barr Virus EBNA2 and Its Coactivator EBNALP controls gene expression

(2020) Qiu Peng et al.   JOURNAL OF VIROLOGY

Structure of a rabies virus polymerase complex from electron cryo-microscopy

(2020) Joshua A. Horwitz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of a paramyxovirus polymerase complex reveals a unique methyltransferase-CTD conformation

(2020) Ryan Abdella et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endoplasmic reticulum contact sites regulate the dynamics of membraneless organelles

(2020) Jason E. Lee et al.   SCIENCE

Replication Compartments of DNA Viruses in the Nucleus: Location, Location, Location

(2020) Matthew Charman et al.   Viruses-Basel

Structure of the Vesicular Stomatitis Virus L Protein in Complex with Its Phosphoprotein Cofactor

(2020) Simon Jenni et al.   Cell Reports

The Role of Promyelocytic Leukemia Nuclear Bodies During HPV Infection

(2020) Lucile G. Guion et al.   Frontiers in Cellular and Infection Microbiology

The Ebola Virus Nucleoprotein Recruits the Nuclear RNA Export Factor NXF1 into Inclusion Bodies to Facilitate Viral Protein Expression

(2020) Lisa Wendt et al.   Cells

G3BP1 Is a Tunable Switch that Triggers Phase Separation to Assemble Stress Granules

(2020) Peiguo Yang et al.   CELL

Measles virus nucleo- and phosphoproteins form liquid-like phase-separated compartments that promote nucleocapsid assembly

(2020) Serafima Guseva et al.   Science Advances

The Cellular Protein CAD is Recruited into Ebola Virus Inclusion Bodies by the Nucleoprotein NP to Facilitate Genome Replication and Transcription

(2020) Janine Brandt et al.   Cells

Ebola Virus Inclusion Body Formation and RNA Synthesis Are Controlled by a Novel Domain of Nucleoprotein Interacting with VP35

(2020) Tsuyoshi Miyake et al.   JOURNAL OF VIROLOGY

Function, Architecture, and Biogenesis of Reovirus Replication Neoorganelles

(2019) Raquel Tenorio et al.   Viruses-Basel

Considerations and Challenges in Studying Liquid-Liquid Phase Separation and Biomolecular Condensates

(2019) Simon Alberti et al.   CELL

Coalescing replication compartments provide the opportunity for recombination between coinfecting herpesviruses

(2019) Enosh Tomer et al.   FASEB JOURNAL

Nipah virus induces two inclusion body populations: Identification of novel inclusions at the plasma membrane

(2019) Marc Ringel et al.   PLoS Pathogens

Evidence for DNA-mediated nuclear compartmentalization distinct from phase separation

(2019) David Trombley McSwiggen et al.   eLife

Influenza A virus ribonucleoproteins form liquid organelles at endoplasmic reticulum exit sites

(2019) Marta Alenquer et al.   Nature Communications

Human antiviral protein MxA forms novel metastable membrane-less cytoplasmic condensates exhibiting rapid reversible tonicity-driven phase transitions

(2019) Deodate Davis et al.   JOURNAL OF VIROLOGY

Measles Virus Forms Inclusion Bodies with Properties of Liquid Organelles

(2019) Yuqin Zhou et al.   JOURNAL OF VIROLOGY

PKR-dependent cytosolic cGAS foci are necessary for intracellular DNA sensing

(2019) Siqi Hu et al.   Science Signaling

Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules

(2018) Sebastian Markmiller et al.   CELL

FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-π Interactions

(2018) Seema Qamar et al.   CELL

In vivo labelling of adenovirus DNA identifies chromatin anchoring and biphasic genome replication.

(2018) Tetsuro Komatsu et al.   JOURNAL OF VIROLOGY

Cytoplasmic Relocalization and Colocalization with Viroplasms of Host Cell Proteins, and Their Role in Rotavirus Infection

(2018) Poonam Dhillon et al.   JOURNAL OF VIROLOGY

High-Density Proximity Mapping Reveals the Subcellular Organization of mRNA-Associated Granules and Bodies

(2018) Ji-Young Youn et al.   MOLECULAR CELL

DNA-induced liquid phase condensation of cGAS activates innate immune signaling

(2018) Mingjian Du et al.   SCIENCE

The dynamics of both filamentous and globular mammalian reovirus viral factories rely on the microtubule network

(2018) Catherine Eichwald et al.   VIROLOGY

RSV hijacks cellular protein phosphatase 1 to regulate M2-1 phosphorylation and viral transcription

(2018) Charles-Adrien Richard et al.   PLoS Pathogens

Rotavirus induces formation of remodeled stress granules and P-bodies and their sequestration in viroplasms to promote progeny virus production

(2018) Poonam Dhillon et al.   JOURNAL OF VIROLOGY

Phase Transitions Drive the Formation of Vesicular Stomatitis Virus Replication Compartments

(2018) Bianca S. Heinrich et al.   mBio

Human Metapneumovirus Induces Formation of Inclusion Bodies for Efficient Genome Replication and Transcription

(2017) Nicolás Cifuentes-Muñoz et al.   JOURNAL OF VIROLOGY

Mammalian Orthoreovirus Factories Modulate Stress Granule Protein Localization by Interaction with G3BP1

(2017) Promisree Choudhury et al.   JOURNAL OF VIROLOGY

Upon Infection, Cellular WD Repeat-Containing Protein 5 (WDR5) Localizes to Cytoplasmic Inclusion Bodies and Enhances Measles Virus Replication

(2017) Dzwokai Ma et al.   JOURNAL OF VIROLOGY

Biomolecular condensates: organizers of cellular biochemistry

(2017) Salman F. Banani et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Assembly of a nucleus-like structure during viral replication in bacteria

(2017) Vorrapon Chaikeeratisak et al.   SCIENCE

Negri bodies are viral factories with properties of liquid organelles

(2017) Jovan Nikolic et al.   Nature Communications

Functional organization of cytoplasmic inclusion bodies in cells infected by respiratory syncytial virus

(2017) Vincent Rincheval et al.   Nature Communications

ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure

(2016) Saumya Jain et al.   CELL

Compositional Control of Phase-Separated Cellular Bodies

(2016) Salman F. Banani et al.   CELL

Toxic PR Poly-Dipeptides Encoded by the C9orf72 Repeat Expansion Target LC Domain Polymers

(2016) Yi Lin et al.   CELL

Coexisting Liquid Phases Underlie Nucleolar Subcompartments

(2016) Marina Feric et al.   CELL

Higher‐order oligomerization promotes localization of SPOP to liquid nuclear speckles

(2016) Melissa R Marzahn et al.   EMBO JOURNAL

Droplet organelles?

(2016) Edward M Courchaine et al.   EMBO JOURNAL

Emerging Role of PML Nuclear Bodies in Innate Immune Signaling

(2016) Myriam Scherer et al.   JOURNAL OF VIROLOGY

Inclusion Body Fusion of Human Parainfluenza Virus Type 3 Regulated by Acetylated α-Tubulin Enhances Viral Replication

(2016) Shengwei Zhang et al.   JOURNAL OF VIROLOGY

Membraneless organelles can melt nucleic acid duplexes and act as biomolecular filters

(2016) Timothy J. Nott et al.   Nature Chemistry

Paramyxovirus RNA synthesis, mRNA editing, and genome hexamer phase: A review

(2016) Daniel Kolakofsky   VIROLOGY

Rabies Virus Infection Induces the Formation of Stress Granules Closely Connected to the Viral Factories

(2016) Jovan Nikolic et al.   PLoS Pathogens

Phase Separation by Low Complexity Domains Promotes Stress Granule Assembly and Drives Pathological Fibrillization

(2015) Amandine Molliex et al.   CELL

Crystal Structure of the Measles Virus Nucleoprotein Core in Complex with an N-Terminal Region of Phosphoprotein

(2015) Sergey G. Guryanov et al.   JOURNAL OF VIROLOGY

Actin-Modulating Protein Cofilin Is Involved in the Formation of Measles Virus Ribonucleoprotein Complex at the Perinuclear Region

(2015) Ritsuko Koga et al.   JOURNAL OF VIROLOGY

Near-atomic cryo-EM structure of the helical measles virus nucleocapsid

(2015) I. Gutsche et al.   SCIENCE

Mx GTPases: dynamin-like antiviral machines of innate immunity

(2015) Otto Haller et al.   TRENDS IN MICROBIOLOGY

Heat Shock Protein 70 Regulates Degradation of the Mumps Virus Phosphoprotein via the Ubiquitin-Proteasome Pathway

(2015) Hiroshi Katoh et al.   JOURNAL OF VIROLOGY

The Nucleocapsid Protein of Human Coronavirus NL63

(2015) Kaja Zuwała et al.   PLoS One

Focal Adhesion Kinase Is Involved in Rabies Virus Infection through Its Interaction with Viral Phosphoprotein P

(2014) Baptiste Fouquet et al.   JOURNAL OF VIROLOGY

The chaperonin CCTα is required for efficient transcription and replication of rabies virus

(2014) Jinyang Zhang et al.   MICROBIOLOGY AND IMMUNOLOGY

DHX36 Enhances RIG-I Signaling by Facilitating PKR-Mediated Antiviral Stress Granule Formation

(2014) Ji-Seung Yoo et al.   PLoS Pathogens

Cellular Chaperonin CCT  Contributes to Rabies Virus Replication during Infection

(2013) J. Zhang et al.   JOURNAL OF VIROLOGY

DNA Virus Replication Compartments

(2013) M. Schmid et al.   JOURNAL OF VIROLOGY

An Amino Acid of Human Parainfluenza Virus Type 3 Nucleoprotein Is Critical for Template Function and Cytoplasmic Inclusion Body Formation

(2013) S. Zhang et al.   JOURNAL OF VIROLOGY

Analysis of Borna Disease Virus Trafficking in Live Infected Cells by Using a Virus Encoding a Tetracysteine-Tagged P Protein

(2013) C. M. Charlier et al.   JOURNAL OF VIROLOGY

MDA5 Localizes to Stress Granules, but This Localization Is Not Required for the Induction of Type I Interferon

(2013) M. A. Langereis et al.   JOURNAL OF VIROLOGY

Structure of the Tetramerization Domain of Measles Virus Phosphoprotein

(2013) G. Communie et al.   JOURNAL OF VIROLOGY

Control of human adenovirus type 5 gene expression by cellular Daxx/ATRX chromatin-associated complexes

(2013) Sabrina Schreiner et al.   NUCLEIC ACIDS RESEARCH

Live-cell imaging of Marburg virus-infected cells uncovers actin-dependent transport of nucleocapsids over long distances

(2013) G. Schudt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sp100 Provides Intrinsic Immunity against Human Papillomavirus Infection

(2013) W. H. Stepp et al.   mBio

The spatio-temporal distribution dynamics of Ebola virus proteins and RNA in infected cells

(2013) Asuka Nanbo et al.   Scientific Reports

Virus factories: biogenesis and structural design

(2012) Isabel Fernández de Castro et al.   CELLULAR MICROBIOLOGY

Inclusion Bodies Are a Site of Ebolavirus Replication

(2012) T. Hoenen et al.   JOURNAL OF VIROLOGY

p38 and OGT Sequestration into Viral Inclusion Bodies in Cells Infected with Human Respiratory Syncytial Virus Suppresses MK2 Activities and Stress Granule Assembly

(2012) Jens Fricke et al.   JOURNAL OF VIROLOGY

The Adenoviral Oncogene E1A-13S Interacts with a Specific Isoform of the Tumor Suppressor PML To Enhance Viral Transcription

(2012) J. Berscheminski et al.   JOURNAL OF VIROLOGY

Hsp70 Protein Positively Regulates Rabies Virus Infection

(2012) X. Lahaye et al.   JOURNAL OF VIROLOGY

Induction of Stress Granule-Like Structures in Vesicular Stomatitis Virus-Infected Cells

(2012) P. X. Dinh et al.   JOURNAL OF VIROLOGY

Correction: Critical Role of an Antiviral Stress Granule Containing RIG-I and PKR in Viral Detection and Innate Immunity

(2012) Koji Onomoto et al.   PLoS One

Rotavirus Viroplasm Fusion and Perinuclear Localization Are Dynamic Processes Requiring Stabilized Microtubules

(2012) Catherine Eichwald et al.   PLoS One

Structural basis for Marburg virus VP35-mediated immune evasion mechanisms

(2012) P. Ramanan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of Promyelocytic Leukemia Protein in Host Antiviral Defense

(2011) Marie-Claude Geoffroy et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Structural Organisation of the Rotavirus Nonstructural Protein NSP5

(2011) Davy Martin et al.   JOURNAL OF MOLECULAR BIOLOGY

Human Cytomegalovirus Infection Causes Degradation of Sp100 Proteins That Suppress Viral Gene Expression

(2011) Y.-E. Kim et al.   JOURNAL OF VIROLOGY

Interplay between Innate Immunity and Negative-Strand RNA Viruses: towards a Rational Model

(2011) D. Gerlier et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Structural disorder within paramyxovirus nucleoproteins and phosphoproteins

(2011) Johnny Habchi et al.   Molecular BioSystems

Active liquid-like behavior of nucleoli determines their size and shape in Xenopus laevis oocytes

(2011) C. P. Brangwynne et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Herpesviral replication compartments move and coalesce at nuclear speckles to enhance export of viral late mRNA

(2011) L. Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Virus factories, double membrane vesicles and viroplasm generated in animal cells

(2011) Christopher L Netherton et al.   Current Opinion in Virology

Structure of the Vesicular Stomatitis Virus N0-P Complex

(2011) Cédric Leyrat et al.   PLoS Pathogens

A Viral Ubiquitin Ligase Has Substrate Preferential SUMO Targeted Ubiquitin Ligase Activity that Counteracts Intrinsic Antiviral Defence

(2011) Chris Boutell et al.   PLoS Pathogens

Rotavirus NSP5 orchestrates recruitment of viroplasmic proteins

(2010) R. Contin et al.   JOURNAL OF GENERAL VIROLOGY

Solution structure of the C-terminal X domain of the measles virus phosphoprotein and interaction with the intrinsically disordered C-terminal domain of the nucleoprotein

(2010) Stéphane Gely et al.   JOURNAL OF MOLECULAR RECOGNITION

Structure of the Dimerization Domain of the Rabies Virus Phosphoprotein

(2010) I. Ivanov et al.   JOURNAL OF VIROLOGY

Resistance to Rabies Virus Infection Conferred by the PMLIV Isoform

(2010) Danielle Blondel et al.   JOURNAL OF VIROLOGY

Formation of Antiviral Cytoplasmic Granules during Orthopoxvirus Infection

(2010) M. Simpson-Holley et al.   JOURNAL OF VIROLOGY

Protein Expression Redirects Vesicular Stomatitis Virus RNA Synthesis to Cytoplasmic Inclusions

(2010) Bianca S. Heinrich et al.   PLoS Pathogens

Differential suppressive effect of promyelocytic leukemia protein on the replication of different subtypes/strains of influenza A virus

(2009) Weizhong Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Parainfluenza virus 5 genomes are located in viral cytoplasmic bodies whilst the virus dismantles the interferon-induced antiviral state of cells

(2009) T. S. Carlos et al.   JOURNAL OF GENERAL VIROLOGY

Modular Organization of Rabies Virus Phosphoprotein

(2009) Francine C.A. Gerard et al.   JOURNAL OF MOLECULAR BIOLOGY

Ebola Virus VP35 Antagonizes PKR Activity through Its C-Terminal Interferon Inhibitory Domain

(2009) M. Schumann et al.   JOURNAL OF VIROLOGY

Mammalian Orthoreovirus Particles Induce and Are Recruited into Stress Granules at Early Times Postinfection

(2009) Q. Qin et al.   JOURNAL OF VIROLOGY

Functional Characterization of Negri Bodies (NBs) in Rabies Virus-Infected Cells: Evidence that NBs Are Sites of Viral Transcription and Replication

(2009) X. Lahaye et al.   JOURNAL OF VIROLOGY

Ebola Virus Protein VP35 Impairs the Function of Interferon Regulatory Factor-Activating Kinases IKK  and TBK-1

(2009) K. C. Prins et al.   JOURNAL OF VIROLOGY

Structure of the vesicular stomatitis virus nucleocapsid in complex with the nucleocapsid-binding domain of the small polymerase cofactor, P

(2009) Todd J. Green et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Germline P Granules Are Liquid Droplets That Localize by Controlled Dissolution/Condensation

(2009) C. P. Brangwynne et al.   SCIENCE

Toll-Like Receptor 3 (TLR3) Plays a Major Role in the Formation of Rabies Virus Negri Bodies

(2009) Pauline Ménager et al.   PLoS Pathogens

Human metapneumovirus nucleoprotein and phosphoprotein interact and provide the minimal requirements for inclusion body formation

(2008) A. Derdowski et al.   JOURNAL OF GENERAL VIROLOGY

Solution Structure of the C-Terminal Nucleoprotein–RNA Binding Domain of the Vesicular Stomatitis Virus Phosphoprotein

(2008) Euripedes A. Ribeiro et al.   JOURNAL OF MOLECULAR BIOLOGY

Live Cell Dynamics of Promyelocytic Leukemia Nuclear Bodies upon Entry into and Exit from Mitosis

(2008) Yi-Chun M. Chen et al.   MOLECULAR BIOLOGY OF THE CELL