Borna disease virus phosphoprotein triggers the organization of viral inclusion bodies by liquid-liquid phase separation

The SARS-CoV-2 nucleocapsid phosphoprotein forms mutually exclusive condensates with RNA and the membrane-associated M protein

(2021) Shan Lu et al.   Nature Communications

GCG inhibits SARS-CoV-2 replication by disrupting the liquid phase condensation of its nucleocapsid protein

(2021) Ming Zhao et al.   Nature Communications

The SARS-CoV-2 nucleocapsid protein is dynamic, disordered, and phase separates with RNA

(2021) Jasmine Cubuk et al.   Nature Communications

A condensate-hardening drug blocks RSV replication in vivo

(2021) Jennifer Risso-Ballester et al.   NATURE

Measles virus nucleo- and phosphoproteins form liquid-like phase-separated compartments that promote nucleocapsid assembly

(2020) Serafima Guseva et al.   Science Advances

Minimal Elements Required for the Formation of Respiratory Syncytial Virus Cytoplasmic Inclusion Bodies In Vivo and In Vitro

(2020) Marie Galloux et al.   mBio

Negri bodies and other virus membrane-less replication compartments

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SARS‐CoV‐2 nucleocapsid protein phase‐separates with RNA and with human hnRNPs

(2020) Theodora Myrto Perdikari et al.   EMBO JOURNAL

Phosphoregulation of Phase Separation by the SARS-CoV-2 N Protein Suggests a Biophysical Basis for its Dual Functions

(2020) Christopher R. Carlson et al.   MOLECULAR CELL

Genomic RNA Elements Drive Phase Separation of the SARS-CoV-2 Nucleocapsid

(2020) Christiane Iserman et al.   MOLECULAR CELL

Nucleocapsid protein of SARS-CoV-2 phase separates into RNA-rich polymerase-containing condensates

(2020) Adriana Savastano et al.   Nature Communications

Nipah virus induces two inclusion body populations: Identification of novel inclusions at the plasma membrane

(2019) Marc Ringel et al.   PLoS Pathogens

Measles Virus Forms Inclusion Bodies with Properties of Liquid Organelles

(2019) Yuqin Zhou et al.   JOURNAL OF VIROLOGY

IUPred2A: context-dependent prediction of protein disorder as a function of redox state and protein binding

(2018) Bálint Mészáros et al.   NUCLEIC ACIDS RESEARCH

RNA buffers the phase separation behavior of prion-like RNA binding proteins

(2018) Shovamayee Maharana et al.   SCIENCE

Phase Transitions Drive the Formation of Vesicular Stomatitis Virus Replication Compartments

(2018) Bianca S. Heinrich et al.   mBio

Negri bodies are viral factories with properties of liquid organelles

(2017) Jovan Nikolic et al.   Nature Communications

Toxic PR Poly-Dipeptides Encoded by the C9orf72 Repeat Expansion Target LC Domain Polymers

(2016) Yi Lin et al.   CELL

Borna Disease Virus Assembles Porous Cage-like Viral Factories in the Nucleus

(2016) Yuya Hirai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synergistic antiviral activity of ribavirin and interferon-α against parrot bornaviruses in avian cells

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A simple and efficient seamless DNA cloning method using SLiCE from Escherichia coli laboratory strains and its application to SLiP site-directed mutagenesis

(2015) Ken Motohashi   BMC BIOTECHNOLOGY

Phase Separation by Low Complexity Domains Promotes Stress Granule Assembly and Drives Pathological Fibrillization

(2015) Amandine Molliex et al.   CELL

X-linked RNA-binding motif protein (RBMX) is required for the maintenance of Borna disease virus nuclear viral factories

(2015) Yuya Hirai et al.   JOURNAL OF GENERAL VIROLOGY

RNA Controls PolyQ Protein Phase Transitions

(2015) Huaiying Zhang et al.   MOLECULAR CELL

Formation and Maturation of Phase-Separated Liquid Droplets by RNA-Binding Proteins

(2015) Yuan Lin et al.   MOLECULAR CELL

Phase Transition of a Disordered Nuage Protein Generates Environmentally Responsive Membraneless Organelles

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RNA transcription modulates phase transition-driven nuclear body assembly

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Liquid demixing of intrinsically disordered proteins is seeded by poly(ADP-ribose)

(2015) Matthias Altmeyer et al.   Nature Communications

Taxonomic reorganization of the family Bornaviridae

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An Amino Acid of Human Parainfluenza Virus Type 3 Nucleoprotein Is Critical for Template Function and Cytoplasmic Inclusion Body Formation

(2013) S. Zhang et al.   JOURNAL OF VIROLOGY

Analysis of Borna Disease Virus Trafficking in Live Infected Cells by Using a Virus Encoding a Tetracysteine-Tagged P Protein

(2013) C. M. Charlier et al.   JOURNAL OF VIROLOGY

Bornavirus Closely Associates and Segregates with Host Chromosomes to Ensure Persistent Intranuclear Infection

(2012) Yusuke Matsumoto et al.   Cell Host & Microbe

Germline P Granules Are Liquid Droplets That Localize by Controlled Dissolution/Condensation

(2009) C. P. Brangwynne et al.   SCIENCE

Human metapneumovirus nucleoprotein and phosphoprotein interact and provide the minimal requirements for inclusion body formation

(2008) A. Derdowski et al.   JOURNAL OF GENERAL VIROLOGY