- Home
- Publications
- Publication Search
- Publication Details
Title
The O-GlcNAcylation and its promotion to hepatocellular carcinoma
Authors
Keywords
-
Journal
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
Volume 1877, Issue 6, Pages 188806
Publisher
Elsevier BV
Online
2022-09-22
DOI
10.1016/j.bbcan.2022.188806
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- EZH2 depletion potentiates MYC degradation inhibiting neuroblastoma and small cell carcinoma tumor formation
- (2022) Liyuan Wang et al. Nature Communications
- Enhanced O-GlcNAc modification induced by the RAS/MAPK/CDK1 pathway is required for SOX2 protein expression and generation of cancer stem cells
- (2022) Masahiro Shimizu et al. Scientific Reports
- Genetic Landscape of Multistep Hepatocarcinogenesis
- (2022) Haruhiko Takeda et al. Cancers
- OGT as potential novel target: Structure, function and inhibitors
- (2022) Ning Zhang et al. CHEMICO-BIOLOGICAL INTERACTIONS
- EZH2 noncanonically binds cMyc and p300 through a cryptic transactivation domain to mediate gene activation and promote oncogenesis
- (2022) Jun Wang et al. NATURE CELL BIOLOGY
- The human O-GlcNAcome database and meta-analysis
- (2021) Eugenia Wulff-Fuentes et al. Scientific Data
- Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
- (2021) Hyuna Sung et al. CA-A CANCER JOURNAL FOR CLINICIANS
- O‐GlcNAcylation promotes the migratory ability of hepatocellular carcinoma cells via regulating FOXA2 stability and transcriptional activity
- (2021) Huang Huang et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Gluconeogenic enzyme PCK1 deficiency promotes CHK2 O-GlcNAcylation and hepatocellular carcinoma growth upon glucose deprivation
- (2021) Jin Xiang et al. JOURNAL OF CLINICAL INVESTIGATION
- The folate cycle enzyme MTHFD2 induces cancer immune evasion through PD-L1 up-regulation
- (2021) Man Shang et al. Nature Communications
- O-GlcNAcylation enhances sensitivity to RSL3-induced ferroptosis via the YAP/TFRC pathway in liver cancer
- (2021) Guoqing Zhu et al. Cell Death Discovery
- Upregulation of OGT by Caveolin‐1 promotes hepatocellular carcinoma cell migration and invasion
- (2021) Lingyan Wang et al. CELL BIOLOGY INTERNATIONAL
- Dual regulation of fatty acid synthase (FASN) expression by O-GlcNAc transferase (OGT) and mTOR pathway in proliferating liver cancer cells
- (2021) Sadia Raab et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Potential therapeutic strategies for targeting Y-box-binding protein 1 in cancers
- (2021) Jia-Wei Yang et al. CURRENT CANCER DRUG TARGETS
- SREBP1-Induced Glutamine Synthetase Triggers a Feedforward Loop to Upregulate SREBP1 through Sp1 O-GlcNAcylation and Augments Lipid Droplet Formation in Cancer Cells
- (2021) Jin-Wei Jhu et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- P53 suppresses the progression of hepatocellular carcinoma via miR‐15a by decreasing OGT expression and EZH2 stabilization
- (2021) Zhenyu You et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- FOXA2 inhibits doxorubicin-induced apoptosis via transcriptionally activating HBP rate-limiting enzyme GFPT1 in HCC cells
- (2021) Huang Huang et al. JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY
- Epigenetic modulation and understanding of HDAC inhibitors in cancer therapy
- (2021) M. Janaki Ramaiah et al. LIFE SCIENCES
- O-GlcNAcylated p53 in the liver modulates hepatic glucose production
- (2021) Maria J. Gonzalez-Rellan et al. Nature Communications
- RANBP2 Activates O-GlcNAcylation through Inducing CEBPα-Dependent OGA Downregulation to Promote Hepatocellular Carcinoma Malignant Phenotypes
- (2021) Xiaoming Liu et al. Cancers
- Transcription Control of Liver Development
- (2021) Evangelia C. Tachmatzidi et al. Cells
- Potential Therapies Targeting Metabolic Pathways in Cancer Stem Cells
- (2021) Yao-An Shen et al. Cells
- c-Myc-driven Hepatocarcinogenesis
- (2021) HYUK MOON et al. ANTICANCER RESEARCH
- Sublethal heat stress-induced O-GlcNAcylation coordinates the Warburg effect to promote hepatocellular carcinoma recurrence and metastasis after thermal ablation
- (2021) Ye Chen et al. CANCER LETTERS
- Glycogen accumulation and phase separation drives liver tumor initiation
- (2021) Qingxu Liu et al. CELL
- O-GlcNAc modified-TIP60/KAT5 is required for PCK1 deficiency-induced HCC metastasis
- (2021) Rui Liu et al. ONCOGENE
- Corosolic acid inhibits cancer progression by decreasing the level of CDK19-mediated O-GlcNAcylation in liver cancer cells
- (2021) Congcong Zhang et al. Cell Death & Disease
- Altered protein O-GlcNAcylation in placentas from mothers with diabetes causes aberrant endocytosis in placental trophoblast cells
- (2021) Victoria Palin et al. Scientific Reports
- Metabolic dysregulation and emerging therapeutical targets for hepatocellular carcinoma
- (2021) Danyu Du et al. Acta Pharmaceutica Sinica B
- Role and Function of O-GlcNAcylation in Cancer
- (2021) Jii Bum Lee et al. Cancers
- Wnt/β-Catenin Signaling as a Driver of Hepatocellular Carcinoma Progression: An Emphasis on Molecular Pathways
- (2021) Mahshid Deldar Abad Paskeh et al. Journal of Hepatocellular Carcinoma
- The positive feedback between ACSL4 expression and O-GlcNAcylation contributes to the growth and survival of hepatocellular carcinoma
- (2020) Jiachen Wang et al. Aging-US
- The clinicopathological and prognostic significance of P27kip in hepatocellular carcinoma patients: A systemic review and meta-analysis
- (2020) Yongxiang Luo et al. GENE
- O-GlcNAcylation regulates the methionine cycle to promote pluripotency of stem cells
- (2020) Qiang Zhu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- ACSL4 promotes hepatocellular carcinoma progression via c-Myc stability mediated by ERK/FBW7/c-Myc axis
- (2020) Junru Chen et al. Oncogenesis
- Prognosis and personalized treatment prediction in TP53-mutant hepatocellular carcinoma: an in silico strategy towards precision oncology
- (2020) Chen Yang et al. BRIEFINGS IN BIOINFORMATICS
- Regulation of histone deacetylase activities and functions by phosphorylation and its physiological relevance
- (2020) Sonali Bahl et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Role of O-Linked N-acetylglucosamine (O-GlcNAc) Protein Modification in Cellular (Patho)Physiology
- (2020) John C. Chatham et al. PHYSIOLOGICAL REVIEWS
- Molecular Bases of Drug Resistance in Hepatocellular Carcinoma
- (2020) Jose J.G. Marin et al. Cancers
- Mitochondrial metabolism and cancer metastasis
- (2020) Dandan Yu et al. Annals of Translational Medicine
- Phosphorylation of the mRNA cap-binding protein eIF4E and cancer
- (2020) Xiaotong Yang et al. CELLULAR SIGNALLING
- O ‐GlcNAcylation modulates HBV replication through regulating cellular autophagy at multiple levels
- (2020) Xueyu Wang et al. FASEB JOURNAL
- Lipopolysaccharide Induces GFAT2 Expression to Promote O-Linked β-N-Acetylglucosaminylation and Attenuate Inflammation in Macrophages
- (2020) Hasanain Al-Mukh et al. JOURNAL OF IMMUNOLOGY
- Metabolic rewiring in the promotion of cancer metastasis: mechanisms and therapeutic implications
- (2020) Qinyao Wei et al. ONCOGENE
- Cancer Metabolism: Phenotype, Signaling and Therapeutic Targets
- (2020) Jae Hyung Park et al. Cells
- Exosomal PD-L1: New Insights Into Tumor Immune Escape Mechanisms and Therapeutic Strategies
- (2020) Kaijian Zhou et al. Frontiers in Cell and Developmental Biology
- Post-translational modifications of EZH2 in cancer
- (2020) Zhongwei Li et al. Cell and Bioscience
- ACSL4 reprograms fatty acid metabolism in hepatocellular carcinoma via c-Myc/SREBP1 pathway
- (2020) Junru Chen et al. CANCER LETTERS
- O‐GlcNAc transferase activates stem‐like cell potential in hepatocarcinoma through O‐GlcNAcylation of eukaryotic initiation factor 4E
- (2019) Benjin Cao et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Reciprocal Regulation Between O-GlcNAcylation and β-Catenin Facilitates Cell Viability and Inhibits Apoptosis in Liver Cancer
- (2019) Sicheng Gao et al. DNA AND CELL BIOLOGY
- High Glucose Triggers Nucleotide Imbalance through O-GlcNAcylation of Key Enzymes and Induces KRAS Mutation in Pancreatic Cells
- (2019) Chun-Mei Hu et al. Cell Metabolism
- Metformin inhibits cervical cancer cell proliferation via decreased AMPK O-GlcNAcylation
- (2019) Min Young Kim et al. Animal Cells and Systems
- Functional microRNA screen uncovers O-linked N-acetylglucosamine transferase as a host factor modulating hepatitis C virus morphogenesis and infectivity
- (2019) Katharina Herzog et al. GUT
- Increased Six1 expression in macrophages promotes hepatocellular carcinoma growth and invasion by regulating MMP‐9
- (2019) Yongyu Zhang et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Analysis of the role of the Hippo pathway in cancer
- (2019) Yanyan Han Journal of Translational Medicine
- Fueling the fire: emerging role of the hexosamine biosynthetic pathway in cancer
- (2019) Neha M. Akella et al. BMC BIOLOGY
- HCF-1 Regulates De Novo Lipogenesis through a Nutrient-Sensitive Complex with ChREBP
- (2019) Elizabeth A. Lane et al. MOLECULAR CELL
- A novel YAP1/SLC35B4 regulatory axis contributes to proliferation and progression of gastric carcinoma
- (2019) Jun Liu et al. Cell Death & Disease
- Inhibiting the Hexosamine Biosynthetic Pathway Lowers O-GlcNAcylation Levels and Sensitizes Cancer to Environmental Stress
- (2019) Lisa A. Walter et al. BIOCHEMISTRY
- O-GlcNAcylated c-Jun antagonizes ferroptosis via inhibiting GSH synthesis in liver cancer
- (2019) Yan Chen et al. CELLULAR SIGNALLING
- Role of acyl-CoA synthetase ACSL4 in arachidonic acid metabolism
- (2019) Hiroshi Kuwata et al. PROSTAGLANDINS & OTHER LIPID MEDIATORS
- Curcumin Ameliorates Nonalcoholic Fatty Liver Disease through Inhibition of O-GlcNAcylation
- (2019) Da Eun Lee et al. Nutrients
- Molecular mechanisms regulating O-linked N-acetylglucosamine (O-GlcNAc)–processing enzymes
- (2019) Dustin T. King et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Tumour evolution in hepatocellular carcinoma
- (2019) Amanda J. Craig et al. Nature Reviews Gastroenterology & Hepatology
- Glutamine-fructose-6-phosphate transaminase 2 (GFPT2) promotes the EMT of serous ovarian cancer by activating the hexosamine biosynthetic pathway to increase the nuclear location of β-catenin
- (2019) Lin Zhou et al. PATHOLOGY RESEARCH AND PRACTICE
- AMOT is required for YAP function in high glucose induced liver malignancy
- (2018) Ya Liu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- SIX1 and DACH1 influence the proliferation and apoptosis of hepatocellular carcinoma through regulating p53
- (2018) Qi Cheng et al. CANCER BIOLOGY & THERAPY
- Transcriptional Regulation of the Warburg Effect in Cancer by SIX1
- (2018) Ling Li et al. CANCER CELL
- O-GlcNAcylation of the Tumor Suppressor FOXO3 Triggers Aberrant Cancer Cell Growth
- (2018) Heon Shin et al. CANCER RESEARCH
- Crosstalk between phosphorylation and O-GlcNAcylation: friend or foe
- (2018) Saar A. M. van der Laarse et al. FEBS Journal
- STAT3 and apoptosis challenges in cancer
- (2018) Nazanin Fathi et al. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
- O -GlcNAcylation of RACK1 promotes hepatocellular carcinogenesis
- (2018) Fangfang Duan et al. JOURNAL OF HEPATOLOGY
- Metabolic reprogramming by PCK1 promotes TCA cataplerosis, oxidative stress and apoptosis in liver cancer cells and suppresses hepatocellular carcinoma
- (2018) Meng-Xi Liu et al. ONCOGENE
- O-GlcNAc elevation through activation of the hexosamine biosynthetic pathway enhances cancer cell chemoresistance
- (2018) Yubo Liu et al. Cell Death & Disease
- Coordination of FOXA2 and SIRT6 suppresses the hepatocellular carcinoma progression through ZEB2 inhibition
- (2018) Jinghua Liu et al. Cancer Management and Research
- The Role for Myc in Coordinating Glycolysis, Oxidative Phosphorylation, Glutaminolysis, and Fatty Acid Metabolism in Normal and Neoplastic Tissues
- (2018) Eric S. Goetzman et al. Frontiers in Endocrinology
- DDX5 promotes hepatocellular carcinoma tumorigenesis via Akt signaling pathway
- (2018) Ying Xue et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Identification of O-GlcNAcylation Modification in Diabetic Retinopathy and Crosstalk with Phosphorylation of STAT3 in Retina Vascular Endothelium Cells
- (2018) Chong Xu et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Silibinin Ameliorates O-GlcNAcylation and Inflammation in a Mouse Model of Nonalcoholic Steatohepatitis
- (2018) Su Lee et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- High glucose stimulates proliferative capacity of liver cancer cells possibly via O -GlcNAcylation-dependent transcriptional regulation of GJC1
- (2018) Yan Chen et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Identification of UAP1L1 as a critical factor for protein O-GlcNAcylation and cell proliferation in human hepatoma cells
- (2018) Ching-Yu Lai et al. ONCOGENE
- O-GlcNAcylation on Rab3A attenuates its effects on mitochondrial oxidative phosphorylation and metastasis in hepatocellular carcinoma
- (2018) Weicheng Wu et al. Cell Death & Disease
- KAT5 promotes invasion and metastasis through C-MYC stabilization in ATC
- (2018) Xi Wei et al. ENDOCRINE-RELATED CANCER
- O-GlcNAcylation promotes colorectal cancer progression by regulating protein stability and potential catcinogenic function of DDX5
- (2018) Nan Wu et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Wnt–β-catenin signalling in liver development, health and disease
- (2018) Maria J. Perugorria et al. Nature Reviews Gastroenterology & Hepatology
- Induced Pluripotent Stem Cells and Their Use in Human Models of Disease and Development
- (2018) Peter Karagiannis et al. PHYSIOLOGICAL REVIEWS
- CHK2 overexpression and mislocalisation within mitotic structures enhances chromosomal instability and hepatocellular carcinoma progression
- (2017) Vinicio Carloni et al. GUT
- Angiomotin Family Members: Oncogenes or Tumor Suppressors?
- (2017) Meng Lv et al. International Journal of Biological Sciences
- O-GlcNAc transferase promotes fatty liver-associated liver cancer through inducing palmitic acid and activating endoplasmic reticulum stress
- (2017) Weiqi Xu et al. JOURNAL OF HEPATOLOGY
- The New Chemical Reporter 6-Alkynyl-6-deoxy-GlcNAc Reveals O-GlcNAc Modification of the Apoptotic Caspases That Can Block the Cleavage/Activation of Caspase-8
- (2017) Kelly N. Chuh et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Regulation of the Hippo-YAP Pathway by Glucose Sensor O-GlcNAcylation
- (2017) Changmin Peng et al. MOLECULAR CELL
- Protein O-GlcNAcylation: emerging mechanisms and functions
- (2017) Xiaoyong Yang et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The essential role of YAP O-GlcNAcylation in high-glucose-stimulated liver tumorigenesis
- (2017) Xiao Zhang et al. Nature Communications
- Role of Y Box Protein-1 in cancer: As potential biomarker and novel therapeutic target
- (2017) Pramod Kumar Maurya et al. Journal of Cancer
- Nucleocytoplasmic human O-GlcNAc transferase is sufficient for O-GlcNAcylation of mitochondrial proteins
- (2016) R. Trapannone et al. BIOCHEMICAL JOURNAL
- Regulation of OGT by URI in Response to Glucose Confers c-MYC-Dependent Survival Mechanisms
- (2016) Stefan Burén et al. CANCER CELL
- Reciprocal regulation between O-GlcNAcylation and tribbles pseudokinase 2 (TRIB2) maintains transformative phenotypes in liver cancer cells
- (2016) Bingjie Yao et al. CELLULAR SIGNALLING
- High Glucose Stimulates Tumorigenesis in Hepatocellular Carcinoma Cells Through AGER-Dependent O-GlcNAcylation of c-Jun
- (2016) Yongxia Qiao et al. DIABETES
- Hyper-O-GlcNAcylation of YB-1 affects Ser102 phosphorylation and promotes cell proliferation in hepatocellular carcinoma
- (2016) Qingqing Liu et al. EXPERIMENTAL CELL RESEARCH
- O-GlcNAcylation of histone deacetylases 1 in hepatocellular carcinoma promotes cancer progression
- (2016) Guizhou Zhu et al. GLYCOBIOLOGY
- The Nutrient-Dependent O -GlcNAc Modification Controls the Expression of Liver Fatty Acid Synthase
- (2016) Steffi F. Baldini et al. JOURNAL OF MOLECULAR BIOLOGY
- Glycogen metabolism has a key role in the cancer microenvironment and provides new targets for cancer therapy
- (2016) Christos E. Zois et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Modification of p27 with O-linked N-acetylglucosamine regulates cell proliferation in hepatocellular carcinoma
- (2016) Huiyuan Qiu et al. MOLECULAR CARCINOGENESIS
- Metastasis and Oxidative Stress: Are Antioxidants a Metabolic Driver of Progression?
- (2015) Maria Peiris-Pagès et al. Cell Metabolism
- Twist-BRD4 Complex: Potential Drug Target for Basal-like Breast Cancer
- (2015) Jian Shi et al. CURRENT PHARMACEUTICAL DESIGN
- A little sugar goes a long way: The cell biology of O-GlcNAc
- (2015) Michelle R. Bond et al. JOURNAL OF CELL BIOLOGY
- Structural Basis of Targeting the Exportin CRM1 in Cancer
- (2015) Achim Dickmanns et al. Cells
- FOXA2 suppresses the metastasis of hepatocellular carcinoma partially through matrix metalloproteinase-9 inhibition
- (2014) Jian Wang et al. CARCINOGENESIS
- Antibodies That DetectO-Linked β-d-N-Acetylglucosamine on the Extracellular Domain of Cell Surface Glycoproteins
- (2014) Yuko Tashima et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- CHK2 kinase in the DNA damage response and beyond
- (2014) L. Zannini et al. Journal of Molecular Cell Biology
- A novel CyclinE/CyclinA-CDK Inhibitor targets p27Kip1 degradation, cell cycle progression and cell survival: Implications in cancer therapy
- (2013) Lu Dai et al. CANCER LETTERS
- Defining the structural origin of the substrate sequence independence of O-GlcNAcase using a combination of molecular docking and dynamics simulation
- (2013) Joanne C Martin et al. GLYCOBIOLOGY
- Impaired Phosphorylation and Ubiquitination by p70 S6 Kinase (p70S6K) and Smad Ubiquitination Regulatory Factor 1 (Smurf1) Promote Tribbles Homolog 2 (TRIB2) Stability and Carcinogenic Property in Liver Cancer
- (2013) Jiayi Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Hyper-O-GlcNAcylation Is Anti-apoptotic and Maintains Constitutive NF-κB Activity in Pancreatic Cancer Cells
- (2013) Zhiyuan Ma et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TRIB2 Acts Downstream of Wnt/TCF in Liver Cancer Cells to Regulate YAP and C/EBPα Function
- (2013) Jiayi Wang et al. MOLECULAR CELL
- Synergistic function of Kras mutation and HBx in initiation and progression of hepatocellular carcinoma in mice
- (2013) H Ye et al. ONCOGENE
- Targeting nuclear kinases in cancer: Development of cell cycle kinase inhibitors
- (2013) Todd M. Pitts et al. PHARMACOLOGY & THERAPEUTICS
- O-GlcNAc Transferase/Host Cell Factor C1 Complex Regulates Gluconeogenesis by Modulating PGC-1α Stability
- (2012) Hai-Bin Ruan et al. Cell Metabolism
- O-GlcNAc Regulates Pluripotency and Reprogramming by Directly Acting on Core Components of the Pluripotency Network
- (2012) Hyonchol Jang et al. Cell Stem Cell
- Enhancer of zeste homolog 2 epigenetically silences multiple tumor suppressor microRNAs to promote liver cancer metastasis
- (2012) Sandy Leung-Kuen Au et al. HEPATOLOGY
- Deciphering the retinoblastoma protein phosphorylation code
- (2012) Seth M. Rubin TRENDS IN BIOCHEMICAL SCIENCES
- Novel candidate colorectal cancer biomarkers identified by methylation microarray-based scanning
- (2011) Y. Mori et al. ENDOCRINE-RELATED CANCER
- A lipid-droplet-targeted O-GlcNAcase isoform is a key regulator of the proteasome
- (2011) C. N. Keembiyehetty et al. JOURNAL OF CELL SCIENCE
- O-GlcNAcylation plays a role in tumor recurrence of hepatocellular carcinoma following liver transplantation
- (2011) Qianqian Zhu et al. MEDICAL ONCOLOGY
- Nuclear Export-independent Inhibition of Foxa2 by Insulin
- (2009) Jessica J. Howell et al. JOURNAL OF BIOLOGICAL CHEMISTRY
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started