Crosstalk between phosphorylation and O-GlcNAcylation: friend or foe

Widespread bacterial protein histidine phosphorylation revealed by mass spectrometry-based proteomics

(2018) Clement M Potel et al.   NATURE METHODS

Middle-down proteomics: a still unexploited resource for chromatin biology

(2017) Simone Sidoli et al.   Expert Review of Proteomics

Peptide microarray analysis of the cross-talk between O-GlcNAcylation and tyrosine phosphorylation

(2017) Jie Shi et al.   FEBS LETTERS

Nuclear factor-erythroid-2 related transcription factor-1 (Nrf1) is regulated by O-GlcNAc transferase

(2017) Jeong Woo Han et al.   FREE RADICAL BIOLOGY AND MEDICINE

O-GlcNAc transferase regulates transcriptional activity of human Oct4

(2017) Sandii Constable et al.   GLYCOBIOLOGY

Checkpoint kinase 1–induced phosphorylation ofO-linked β-N-acetylglucosamine transferase regulates the intermediate filament network during cytokinesis

(2017) Zhe Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hyper-O-GlcNAcylation activates nuclear factor κ-light-chain-enhancer of activated B cells (NF-κB) signaling through interplay with phosphorylation and acetylation

(2017) Zhiyuan Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Recent advances in methods for the analysis of protein o-glycosylation at proteome level

(2017) Xin You et al.   JOURNAL OF SEPARATION SCIENCE

O-GlcNAcylation of STAT5 controls tyrosine phosphorylation and oncogenic transcription in STAT5-dependent malignancies

(2017) P Freund et al.   LEUKEMIA

Structural and functional insight into human O-GlcNAcase

(2017) Christian Roth et al.   Nature Chemical Biology

Insights into activity and inhibition from the crystal structure of human O-GlcNAcase

(2017) Nathaniel L Elsen et al.   Nature Chemical Biology

Protein O-GlcNAcylation: emerging mechanisms and functions

(2017) Xiaoyong Yang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Elucidating crosstalk mechanisms between phosphorylation and O-GlcNAcylation

(2017) Aneika C. Leney et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metabolic labeling in middle-down proteomics allows for investigation of the dynamics of the histone code

(2017) Simone Sidoli et al.   Epigenetics & Chromatin

Structural insights into the substrate binding adaptability and specificity of human O-GlcNAcase

(2017) Baobin Li et al.   Nature Communications

Recognition of a glycosylation substrate by the O-GlcNAc transferase TPR repeats

(2017) Karim Rafie et al.   Open Biology

Potential coordination role between O-GlcNAcylation and epigenetics

(2017) Donglu Wu et al.   Protein & Cell

Distributive O-GlcNAcylation on the Highly Repetitive C-Terminal Domain of RNA Polymerase II

(2016) Lei Lu et al.   BIOCHEMISTRY

O-LinkedN-Acetylglucosamine (O-GlcNAc) Transferase andO-GlcNAcase Interact with Mi2β Protein at theAγ-Globin Promoter

(2016) Zhen Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Profiling of Histone Post-Translational Modifications in Mouse Brain with High-Resolution Top-Down Mass Spectrometry

(2016) Mowei Zhou et al.   JOURNAL OF PROTEOME RESEARCH

Native Mass Spectrometry: What is in the Name?

(2016) Aneika C. Leney et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Roles of O-GlcNAc in chronic diseases of aging

(2016) Partha S. Banerjee et al.   MOLECULAR ASPECTS OF MEDICINE

Activity Based High-Throughput Screening for Novel O-GlcNAc Transferase Substrates Using a Dynamic Peptide Microarray

(2016) Jie Shi et al.   PLoS One

SOX2 O-GlcNAcylation alters its protein-protein interactions and genomic occupancy to modulate gene expression in pluripotent cells

(2016) Samuel A Myers et al.   eLife

Identification of the nuclear localisation signal of O-GlcNAc transferase and its nuclear import regulation

(2016) Hyeon Gyu Seo et al.   Scientific Reports

Benchmarking Multiple Fragmentation Methods on an Orbitrap Fusion for Top-down Phospho-Proteoform Characterization

(2015) Andrea M. Brunner et al.   ANALYTICAL CHEMISTRY

Phosphoproteomics in the Age of Rapid and Deep Proteome Profiling

(2015) Nicholas M. Riley et al.   ANALYTICAL CHEMISTRY

Regulatory O-GlcNAcylation sites on FoxO1 are yet to be identified

(2015) Yann Fardini et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Akt/PKB: one kinase, many modifications

(2015) Guillermo Risso et al.   BIOCHEMICAL JOURNAL

A two-layered machine learning method to identify protein O-GlcNAcylation sites with O-GlcNAc transferase substrate motifs

(2015) Hui-Ju Kao et al.   BMC BIOINFORMATICS

The interplay of histone modifications - writers that read

(2015) T. Zhang et al.   EMBO REPORTS

Undetectable histone O-GlcNAcylation in mammalian cells

(2015) Jessica Gagnon et al.   Epigenetics

PGlcS: Prediction of protein O-GlcNAcylation sites with multiple features and analysis

(2015) Xiaowei Zhao et al.   JOURNAL OF THEORETICAL BIOLOGY

Chromatin-wide Profiling of DYRK1A Reveals a Role as a Gene-Specific RNA Polymerase II CTD Kinase

(2015) Chiara Di Vona et al.   MOLECULAR CELL

The active site of O-GlcNAc transferase imposes constraints on substrate sequence

(2015) Shalini Pathak et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Glycogen synthase kinase-3 (GSK3): Regulation, actions, and diseases

(2015) Eleonore Beurel et al.   PHARMACOLOGY & THERAPEUTICS

Detection and identification ofO-GlcNAcylated proteins by proteomic approaches

(2015) Anne-Sophie Vercoutter-Edouart et al.   PROTEOMICS

Tissue-based map of the human proteome

(2015) M. Uhlen et al.   SCIENCE

The active site of O-GlcNAc transferase imposes constraints on substrate sequence

(2015) Shalini Pathak et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Systematic Analysis and Prediction ofIn SituCross Talk of O-GlcNAcylation and Phosphorylation

(2015) Heming Yao et al.   Biomed Research International

Mass Spectrometry-Based Detection and Assignment of Protein Posttranslational Modifications

(2014) Sophia Doll et al.   ACS Chemical Biology

Simultaneous Assessment of Kinetic, Site-Specific, and Structural Aspects of Enzymatic Protein Phosphorylation

(2014) Michiel van de Waterbeemd et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nutrient Regulation of Signaling, Transcription, and Cell Physiology by O-GlcNAcylation

(2014) Stéphan Hardivillé et al.   Cell Metabolism

O-GlcNAcylation stabilizes β-catenin through direct competition with phosphorylation at threonine 41

(2014) Stéphanie Olivier-Van Stichelen et al.   FASEB JOURNAL

AMP-activated protein kinase mediates the antioxidant effects of resveratrol through regulation of the transcription factor FoxO1

(2014) Hee Yun et al.   FEBS Journal

Cross-talk between Two Essential Nutrient-sensitive Enzymes

(2014) John W. Bullen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Microarray Discovery of New OGT Substrates: The Medulloblastoma Oncogene OTX2 Is O-GlcNAcylated

(2014) Rodrigo F. Ortiz-Meoz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Post-translational modifications of intermediate filament proteins: mechanisms and functions

(2014) Natasha T. Snider et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

AMPK regulates histone H2B O-GlcNAcylation

(2014) Qiuran Xu et al.   NUCLEIC ACIDS RESEARCH

Global identification ofO-GlcNAc transferase (OGT) interactors by a human proteome microarray and the construction of an OGT interactome

(2014) Rui-Ping Deng et al.   PROTEOMICS

Proteomic approaches for site-specific O-GlcNAcylation analysis

(2014) Sheng Wang et al.   Bioanalysis

Physicochemical mechanisms of protein regulation by phosphorylation

(2014) Hafumi Nishi et al.   Frontiers in Genetics

O-GlcNAc Cycling: A Link Between Metabolism and Chronic Disease

(2013) Michelle R. Bond et al.   Annual Review of Nutrition

Validation of the reliability of computational O-GlcNAc prediction

(2013) Ramona Jochmann et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Glucose Sensor O-GlcNAcylation Coordinates with Phosphorylation to Regulate Circadian Clock

(2013) Krista Kaasik et al.   Cell Metabolism

Insulin signaling controls the expression of O-GlcNAc transferase and its interaction with lipid microdomains

(2013) Yobana Perez-Cervera et al.   FASEB JOURNAL

Status of Large-scale Analysis of Post-translational Modifications by Mass Spectrometry

(2013) Jesper V. Olsen et al.   MOLECULAR & CELLULAR PROTEOMICS

O-GlcNAcPRED: a sensitive predictor to capture protein O-GlcNAcylation sites

(2013) Cang-Zhi Jia et al.   Molecular BioSystems

Evolution and functional cross-talk of protein post-translational modifications

(2013) Pedro Beltrao et al.   Molecular Systems Biology

The next level of complexity: Crosstalk of posttranslational modifications

(2013) A. Saskia Venne et al.   PROTEOMICS

HCF-1 Is Cleaved in the Active Site of O-GlcNAc Transferase

(2013) M. B. Lazarus et al.   SCIENCE

Cracking the O-GlcNAc code in metabolism

(2013) Hai-Bin Ruan et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Structure of a bacterial putative acetyltransferase defines the fold of the human O-GlcNAcase C-terminal domain

(2013) F. V. Rao et al.   Open Biology

O-GlcNAcylation of kinases

(2012) Wagner B. Dias et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Regulatory modules: Coupling protein stability to phopshoregulation during cell division

(2012) Liam J. Holt   FEBS LETTERS

Global Identification and Characterization of BothO-GlcNAcylation and Phosphorylation at the Murine Synapse

(2012) Jonathan C. Trinidad et al.   MOLECULAR & CELLULAR PROTEOMICS

Regulation of CK2 by phosphorylation and O-GlcNAcylation revealed by semisynthesis

(2012) Mary Katherine Tarrant et al.   Nature Chemical Biology

ERK1/2 MAP kinases: Structure, function, and regulation

(2012) Robert Roskoski   PHARMACOLOGICAL RESEARCH

Modular evolution of phosphorylation-based signalling systems

(2012) J. Jin et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

BRD4 is an atypical kinase that phosphorylates Serine2 of the RNA Polymerase II carboxy-terminal domain

(2012) B. N. Devaiah et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Kinase Consensus Sequences: A Breeding Ground for Crosstalk

(2011) Heather L. Rust et al.   ACS Chemical Biology

Cross Talk Between O-GlcNAcylation and Phosphorylation: Roles in Signaling, Transcription, and Chronic Disease

(2011) Gerald W. Hart et al.   Annual Review of Biochemistry

Glycans as cancer biomarkers

(2011) Barbara Adamczyk et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

dbOGAP - An Integrated Bioinformatics Resource for Protein O-GlcNAcylation

(2011) Jinlian Wang et al.   BMC BIOINFORMATICS

O-GlcNAc modification: why so intimately associated with phosphorylation?

(2011) Suresh Mishra et al.   Cell Communication and Signaling

The Cyclin K/Cdk12 complex maintains genomic stability via regulation of expression of DNA damage response genes

(2011) D. Blazek et al.   GENES & DEVELOPMENT

GlcNAcylation of histone H2B facilitates its monoubiquitination

(2011) Ryoji Fujiki et al.   NATURE

Structure of human O-GlcNAc transferase and its complex with a peptide substrate

(2011) Michael B. Lazarus et al.   NATURE

Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells

(2011) S. A. Myers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNAP II CTD Phosphorylated on Threonine-4 Is Required for Histone mRNA 3' End Processing

(2011) J.-P. Hsin et al.   SCIENCE

Proteome-wide post-translational modification statistics: frequency analysis and curation of the swiss-prot database

(2011) George A. Khoury et al.   Scientific Reports

Site-specific interplay between O-GlcNAcylation and phosphorylation in cellular regulation

(2010) Ping Hu et al.   FEBS LETTERS

BlockingO-Linked GlcNAc Cycling inDrosophilaInsulin-producing Cells Perturbs Glucose-Insulin Homeostasis

(2010) Osamu Sekine et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulating the Regulators: The Post-Translational Code of Class I HDAC1 and HDAC2

(2010) Chiara V. Segré et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

 -N-acetylglucosamine (O-GlcNAc) is part of the histone code

(2010) K. Sakabe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Extensive Crosstalk Between O-GlcNAcylation and Phosphorylation Regulates Cytokinesis

(2010) Z. Wang et al.   Science Signaling

O-linked β-N-acetylglucosamine (O-GlcNAc): Extensive crosstalk with phosphorylation to regulate signaling and transcription in response to nutrients and stress

(2009) Chutikarn Butkinaree et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

The phosphoproteomics data explosion

(2009) Simone Lemeer et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

SH2 domains: modulators of nonreceptor tyrosine kinase activity

(2009) Panagis Filippakopoulos et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Regulation of Calcium/Calmodulin-dependent Kinase IV byO-GlcNAc Modification

(2009) Wagner B. Dias et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

O-LinkedN-Acetylglucosamine Modification of Insulin Receptor Substrate-1 Occurs in Close Proximity to Multiple SH2 Domain Binding Motifs

(2009) Amanda L. Klein et al.   MOLECULAR & CELLULAR PROTEOMICS

Loss of p53 enhances catalytic activity of IKK  through O-linked  -N-acetyl glucosamine modification

(2009) K. Kawauchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of protein O-GlcNAcylation sites using electron transfer dissociation mass spectrometry on native peptides

(2009) R. J. Chalkley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A post-translational modification code for transcription factors: sorting through a sea of signals

(2009) Bérénice A. Benayoun et al.   TRENDS IN CELL BIOLOGY

Regulation of IκB Kinase Complex by Phosphorylation of γ-Binding Domain of IκB Kinase β by Polo-like Kinase 1

(2008) Tomoyasu Higashimoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

O-Linked β-N-Acetylglucosaminyltransferase Substrate Specificity Is Regulated by Myosin Phosphatase Targeting and Other Interacting Proteins

(2008) Win D. Cheung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterization of β-N-Acetylglucosaminidase Cleavage by Caspase-3 during Apoptosis

(2008) Chutikarn Butkinaree et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

O-GlcNAc Regulates FoxO Activation in Response to Glucose

(2008) Michael P. Housley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AMP-activated Protein Kinase and p38 MAPK ActivateO-GlcNAcylation of Neuronal Proteins during Glucose Deprivation

(2008) Win D. Cheung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of theO-Linked β-N-Acetylglucosamine Transferase by Insulin Signaling

(2008) Stephen A. Whelan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance

(2008) Xiaoyong Yang et al.   NATURE

Chemical approaches to understanding O-GlcNAc glycosylation in the brain

(2008) Jessica E Rexach et al.   Nature Chemical Biology

Cross-talk between GlcNAcylation and phosphorylation: Site-specific phosphorylation dynamics in response to globally elevated O-GlcNAc

(2008) Z. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA