ACSL4 reprograms fatty acid metabolism in hepatocellular carcinoma via c-Myc/SREBP1 pathway

ACSL4 promotes hepatocellular carcinoma progression via c-Myc stability mediated by ERK/FBW7/c-Myc axis

(2020) Junru Chen et al.   Oncogenesis

Hepatocellular carcinoma: Current situation and challenge

(2019) Zhao Li et al.   Hepatobiliary & Pancreatic Diseases International

SREBP1 drives Keratin-80-dependent cytoskeletal changes and invasive behavior in endocrine-resistant ERα breast cancer

(2019) Ylenia Perone et al.   Nature Communications

The MYC Oncogene Cooperates with Sterol-Regulated Element-Binding Protein to Regulate Lipogenesis Essential for Neoplastic Growth

(2019) Arvin M. Gouw et al.   Cell Metabolism

Chemical genetics in tumor lipogenesis

(2018) Simone Braig   BIOTECHNOLOGY ADVANCES

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Inhibition of the sterol regulatory element-binding protein pathway suppresses hepatocellular carcinoma by repressing inflammation in mice

(2017) Na Li et al.   HEPATOLOGY

Myc Expression Drives Aberrant Lipid Metabolism in Lung Cancer

(2016) Z. Hall et al.   CANCER RESEARCH

Tumor-suppressive functions of long-chain acyl-CoA synthetase 4 in gastric cancer

(2016) Xiaojuan Ye et al.   IUBMB LIFE

ATP Citrate Lyase (ACLY): A Promising Target for Cancer Prevention and Treatment

(2015) Amrita Khwairakpam et al.   CURRENT DRUG TARGETS

Targeting SREBP-1-driven Lipid Metabolism to Treat Cancer

(2015) Deliang Guo et al.   CURRENT PHARMACEUTICAL DESIGN

SREBP-1 Has a Prognostic Role and Contributes to Invasion and Metastasis in Human Hepatocellular Carcinoma

(2014) Chao Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

c-Myc Programs Fatty Acid Metabolism and Dictates Acetyl-CoA Abundance and Fate

(2014) Lia R. Edmunds et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cellular Fatty Acid Metabolism and Cancer

(2013) Erin Currie et al.   Cell Metabolism

Hooked on fat: the role of lipid synthesis in cancer metabolism and tumour development

(2013) F. Baenke et al.   Disease Models & Mechanisms

Integrated Metabolite and Gene Expression Profiles Identify Lipid Biomarkers Associated With Progression of Hepatocellular Carcinoma and Patient Outcomes

(2013) Anuradha Budhu et al.   GASTROENTEROLOGY

Stearoyl-CoA desaturase plays an important role in proliferation and chemoresistance in human hepatocellular carcinoma

(2013) Samiksha Bansal et al.   JOURNAL OF SURGICAL RESEARCH

Sterol regulatory element-binding protein 1 is required for ovarian tumor growth

(2013) LONG-YUN NIE et al.   ONCOLOGY REPORTS

Transcriptional Control of Hepatic Lipid Metabolism by SREBP and ChREBP

(2013) Xu Xu et al.   SEMINARS IN LIVER DISEASE

Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate

(2012) Patrick S. Ward et al.   CANCER CELL

ATP-Citrate Lyase: A Key Player in Cancer Metabolism

(2012) N. Zaidi et al.   CANCER RESEARCH

Expanding Roles for SREBP in Metabolism

(2012) Wei Shao et al.   Cell Metabolism

Expression of R132H Mutational IDH1 in Human U87 Glioblastoma Cells Affects the SREBP1a Pathway and Induces Cellular Proliferation

(2012) Jian Zhu et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Reductive carboxylation supports growth in tumour cells with defective mitochondria

(2011) Andrew R. Mullen et al.   NATURE

Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia

(2011) Christian M. Metallo et al.   NATURE

Activation of lipogenic pathway correlates with cell proliferation and poor prognosis in hepatocellular carcinoma

(2008) Taro Yamashita et al.   JOURNAL OF HEPATOLOGY