Metabolic reprogramming by PCK1 promotes TCA cataplerosis, oxidative stress and apoptosis in liver cancer cells and suppresses hepatocellular carcinoma

Inhibition and Allosteric Regulation of Monomeric Phosphoenolpyruvate Carboxykinase by 3-Mercaptopicolinic Acid

(2015) Marc D. Balan et al.   BIOCHEMISTRY

Glutamate Dehydrogenase 1 Signals through Antioxidant Glutathione Peroxidase 1 to Regulate Redox Homeostasis and Tumor Growth

(2015) Lingtao Jin et al.   CANCER CELL

A miR-130a-YAP positive feedback loop promotes organ size and tumorigenesis

(2015) Shuying Shen et al.   CELL RESEARCH

SIRT3-dependent GOT2 acetylation status affects the malate-aspartate NADH shuttle activity and pancreatic tumor growth

(2015) H. Yang et al.   EMBO JOURNAL

Mitochondrial metabolism mediates oxidative stress and inflammation in fatty liver

(2015) Santhosh Satapati et al.   JOURNAL OF CLINICAL INVESTIGATION

PEPCK Coordinates the Regulation of Central Carbon Metabolism to Promote Cancer Cell Growth

(2015) Emily D. Montal et al.   MOLECULAR CELL

Mitochondrial Phosphoenolpyruvate Carboxykinase Regulates Metabolic Adaptation and Enables Glucose-Independent Tumor Growth

(2015) Emma E. Vincent et al.   MOLECULAR CELL

Fructose-1,6-bisphosphatase opposes renal carcinoma progression

(2014) Bo Li et al.   NATURE

PCK2 activation mediates an adaptive response to glucose depletion in lung cancer

(2014) K Leithner et al.   ONCOGENE

Role of the Microenvironment in the Pathogenesis and Treatment of Hepatocellular Carcinoma

(2013) Virginia Hernandez–Gea et al.   GASTROENTEROLOGY

PEPCK-M expression in mouse liver potentiates, not replaces, PEPCK-C mediated gluconeogenesis

(2013) Andrés Méndez-Lucas et al.   JOURNAL OF HEPATOLOGY

The Proto-oncometabolite Fumarate Binds Glutathione to Amplify ROS-Dependent Signaling

(2013) Lucas B. Sullivan et al.   MOLECULAR CELL

Stromal cells in tumor microenvironment and breast cancer

(2012) Yan Mao et al.   CANCER AND METASTASIS REVIEWS

Phosphoglycerate Mutase 1 Coordinates Glycolysis and Biosynthesis to Promote Tumor Growth

(2012) Taro Hitosugi et al.   CANCER CELL

Excessive Hepatic Mitochondrial TCA Cycle and Gluconeogenesis in Humans with Nonalcoholic Fatty Liver Disease

(2011) Nishanth E. Sunny et al.   Cell Metabolism

A New Method for Isolation of Interstitial Fluid from Human Solid Tumors Applied to Proteomic Analysis of Ovarian Carcinoma Tissue

(2011) Hanne Haslene-Hox et al.   PLoS One

Quantitative Metabolome Profiling of Colon and Stomach Cancer Microenvironment by Capillary Electrophoresis Time-of-Flight Mass Spectrometry

(2009) A. Hirayama et al.   CANCER RESEARCH

What Is the Metabolic Role of Phosphoenolpyruvate Carboxykinase?

(2009) Jianqi Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

Cancer Cell Metabolism: Warburg and Beyond

(2008) Peggy P. Hsu et al.   CELL