O-GlcNAc elevation through activation of the hexosamine biosynthetic pathway enhances cancer cell chemoresistance

The New Chemical Reporter 6-Alkynyl-6-deoxy-GlcNAc Reveals O-GlcNAc Modification of the Apoptotic Caspases That Can Block the Cleavage/Activation of Caspase-8

(2017) Kelly N. Chuh et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Small Molecule That Inhibits OGT Activity in Cells

(2015) Rodrigo F. Ortiz-Meoz et al.   ACS Chemical Biology

O-GlcNAc signaling in cancer metabolism and epigenetics

(2015) Jay Prakash Singh et al.   CANCER LETTERS

OGT Mediated Histone H2B S112 GlcNAcylation Regulates DNA Damage Response

(2015) Panfei Wang et al.   Journal of Genetics and Genomics

Linking Cancer Metabolism to DNA Repair and Accelerated Senescence

(2015) E. V. Efimova et al.   MOLECULAR CANCER RESEARCH

Quantitative phosphoproteomics reveals crosstalk between phosphorylation andO-GlcNAc in the DNA damage response pathway

(2015) Jun Zhong et al.   PROTEOMICS

Akt Inhibitor MK2206 Prevents Influenza pH1N1 Virus InfectionIn Vitro

(2014) Oxana V. Denisova et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Multi-drug resistance in cancer chemotherapeutics: Mechanisms and lab approaches

(2014) Qiong Wu et al.   CANCER LETTERS

Spliced X-Box Binding Protein 1 Couples the Unfolded Protein Response to Hexosamine Biosynthetic Pathway

(2014) Zhao V. Wang et al.   CELL

JunB protects β-cells from lipotoxicity via the XBP1–AKT pathway

(2014) D A Cunha et al.   CELL DEATH AND DIFFERENTIATION

Targeting cellular metabolism to improve cancer therapeutics

(2013) Y Zhao et al.   Cell Death & Disease

O-GlcNAc modification affects the ATM-mediated DNA damage response

(2012) Yuri Miura et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Cancer Cell Metabolism: One Hallmark, Many Faces

(2012) Jason R. Cantor et al.   Cancer Discovery

MiR-34a inhibits lymphatic metastasis potential of mouse hepatoma cells

(2011) Yanjie Guo et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Anticancer Targets in the Glycolytic Metabolism of Tumors: A Comprehensive Review

(2011) Paolo E. Porporato et al.   Frontiers in Pharmacology

The dynamic stress-induced “O-GlcNAc-ome” highlights functions for O-GlcNAc in regulating DNA damage/repair and other cellular pathways

(2010) Natasha E. Zachara et al.   AMINO ACIDS

O-GlcNAc signaling: a metabolic link between diabetes and cancer?

(2010) C. Slawson et al.   TRENDS IN BIOCHEMICAL SCIENCES

Glutamine enhances heat shock protein 70 expression via increased hexosamine biosynthetic pathway activity

(2009) Christine R. Hamiel et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

O-linked β-N-acetylglucosamine (O-GlcNAc): Extensive crosstalk with phosphorylation to regulate signaling and transcription in response to nutrients and stress

(2009) Chutikarn Butkinaree et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Glycolysis: a bioenergetic or a survival pathway?

(2009) Juan P. Bolaños et al.   TRENDS IN BIOCHEMICAL SCIENCES

Preventing the unfolded protein response via aberrant activation of 4E-binding protein 1 by versipelostatin

(2008) Junichi Matsuo et al.   CANCER SCIENCE