Flavonoids bridging the gut and the brain: Intestinal metabolic fate, and direct or indirect effects of natural supporters against neuroinflammation and neurodegeneration

Soybean Meal Extract Preserves Memory Ability by Increasing Presynaptic Function and Modulating Gut Microbiota in Rats

(2022) Kun-Chieh Yeh et al.   MOLECULAR NEUROBIOLOGY

Genistein: A Review on its Anti-Inflammatory Properties

(2022) Yu Xian Goh et al.   Frontiers in Pharmacology

Calycosin Alleviates Paraquat-Induced Neurodegeneration by Improving Mitochondrial Functions and Regulating Autophagy in a Drosophila Model of Parkinson’s Disease

(2022) Hitesh Singh Chaouhan et al.   Antioxidants

Exploring the multifactorial aspects of Gut Microbiome in Parkinson’s Disease

(2022) Sujith Pavan et al.   FOLIA MICROBIOLOGICA

The multimodal action of genistein in Alzheimer's and other age-related diseases

(2022) Cristina Mas-Bargues et al.   FREE RADICAL BIOLOGY AND MEDICINE

In Vitro Microbial Metabolism of (+)-Catechin Reveals Fast and Slow Converters with Individual-Specific Microbial and Metabolite Markers

(2022) Qiqiong Li et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Diet Patterns, the Gut Microbiome, and Alzheimer’s Disease

(2022) Andrea McGrattan et al.   JOURNAL OF ALZHEIMERS DISEASE

Genistein: A focus on several neurodegenerative diseases

(2022) Rongzi Li et al.   JOURNAL OF FOOD BIOCHEMISTRY

Epigallocatechin gallate: Phytochemistry, bioavailability, utilization challenges, and strategies

(2022) Shomaila Mehmood et al.   JOURNAL OF FOOD BIOCHEMISTRY

Bioactive compounds for neuropathic pain: An update on preclinical studies and future perspectives

(2022) Chwan-Li Shen et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

The Role of Microbiome in Brain Development and Neurodegenerative Diseases

(2022) Varsha Nandwana et al.   MOLECULES

Protective effects of functional foods against Parkinson's disease: A narrative review on pharmacology, phytochemistry, and molecular mechanisms

(2022) Milad Iranshahy et al.   PHYTOTHERAPY RESEARCH

The Inverse Correlation of Isoflavone Dietary Intake and Headache in Peri- and Post-Menopausal Women

(2022) Mayuko Kazama et al.   Nutrients

Bioactive Compounds for Fibromyalgia-like Symptoms: A Narrative Review and Future Perspectives

(2022) Chwan-Li Shen et al.   International Journal of Environmental Research and Public Health

Microbiota and Pain: Save Your Gut Feeling

(2022) Chiara Morreale et al.   Cells

Epigallocatechin-3-Gallate (EGCG): New Therapeutic Perspectives for Neuroprotection, Aging, and Neuroinflammation for the Modern Age

(2022) Ashley Payne et al.   Biomolecules

Does Plant Breeding for Antioxidant-Rich Foods Have an Impact on Human Health?

(2022) Laura Bassolino et al.   Antioxidants

Exploring the potential antidepressant mechanisms of puerarin: Anti-inflammatory response via the gut-brain axis

(2022) Xujiao Song et al.   JOURNAL OF AFFECTIVE DISORDERS

Role of gut microbiota in neuropathy and neuropathic pain states: A systematic preclinical review

(2022) Katia Pane et al.   NEUROBIOLOGY OF DISEASE

Curcumin, Quercetin, Catechins and Metabolic Diseases: The Role of Gut Microbiota

(2021) Umair Shabbir et al.   Nutrients

Inhibitory Mechanism of the Isoflavone Derivative Genistein in the Human CaV3.3 Channel

(2021) Maricruz Rangel-Galván et al.   ACS Chemical Neuroscience

Antinociceptive effects of maqui-berry (Aristotelia chilensis (Mol.) Stuntz)

(2021) Vicente Agulló et al.   INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION

Quercetin-Conjugated Superparamagnetic Iron Oxide Nanoparticles Protect AlCl3-Induced Neurotoxicity in a Rat Model of Alzheimer’s Disease via Antioxidant Genes, APP Gene, and miRNA-101

(2021) Elnaz Amanzadeh Jajin et al.   Frontiers in Neuroscience

The Impact of Microbiota on the Pathogenesis of Amyotrophic Lateral Sclerosis and the Possible Benefits of Polyphenols. An Overview

(2021) Julia Casani-Cubel et al.   Metabolites

Administration of quercetin improves mitochondria quality control and protects the neurons in 6-OHDA-lesioned Parkinson's disease models

(2021) Wen-Wen Wang et al.   Aging-US

Mechanistic new insights of flavonols on neurodegenerative diseases

(2021) Muhammad Shoaib Tahir et al.   BIOMEDICINE & PHARMACOTHERAPY

Quercetin Alleviates Neuropathic Pain in the Rat CCI Model by Mediating AMPK/MAPK Pathway

(2021) Guangyao Ye et al.   Journal of Pain Research

Epigallocatechin Gallate in Relapsing-Remitting Multiple Sclerosis

(2021) Judith Bellmann-Strobl et al.   Neurology-Neuroimmunology & Neuroinflammation

Local administration of genistein as a local anesthetic agent inhibits the trigeminal nociceptive neuronal activity in rats

(2021) Manaka Yamaguchi et al.   BRAIN RESEARCH BULLETIN

Interactions between dietary flavonoids and the gut microbiome: A comprehensive review

(2021) Mostafa H. Baky et al.   BRITISH JOURNAL OF NUTRITION

Pharmacological implications of ipriflavone against environmental metal–induced neurodegeneration and dementia in rats

(2021) Hend M. Hussien et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Antioxidant activity of calycosin against α-synuclein amyloid fibrils-induced oxidative stress in neural-like cells as a model of preventive care studies in Parkinson's disease

(2021) Qichen Pan et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Genistein reverses the effect of 17β‐estradiol on exacerbating experimental occlusal interference‐induced chronic masseter hyperalgesia in ovariectomised rats

(2021) Yun Liu et al.   JOURNAL OF ORAL REHABILITATION

Anthocyanin-rich Blueberry Extracts and Anthocyanin Metabolite Protocatechuic Acid promote Autophagy-lysosomal Pathway and alleviate Neurons Damage in vivo and in vitro Models of Alzheimer's Disease

(2021) Hui Li et al.   NUTRITION

Therapeutic Potential of Isoflavones with an Emphasis on Daidzein

(2021) Mohammed M. Alshehri et al.   Oxidative Medicine and Cellular Longevity

Genistein-3′-sodium sulfonate ameliorates cerebral ischemia injuries by blocking neuroinflammation through the α7nAChR-JAK2/STAT3 signaling pathway in rats

(2021) Jiali Xie et al.   PHYTOMEDICINE

Modulation of the Gut Microbiota Structure with Probiotics and Isoflavone Alleviates Metabolic Disorder in Ovariectomized Mice

(2021) Qian Chen et al.   Nutrients

Possible Role of Butyrylcholinesterase in Fat Loss and Decreases in Inflammatory Levels in Patients with Multiple Sclerosis after Treatment with Epigallocatechin Gallate and Coconut Oil: A Pilot Study

(2021) Jose Enrique de la Rubia Ortí et al.   Nutrients

Roles and Mechanisms of Gut Microbiota in Patients With Alzheimer’s Disease

(2021) Shaochang Wu et al.   Frontiers in Aging Neuroscience

Quercetin hinders microglial activation to alleviate neurotoxicity via the interplay between NLRP3 inflammasome and mitophagy

(2021) Xiaojuan Han et al.   Redox Biology

Isoflavone diet ameliorates experimental autoimmune encephalomyelitis through modulation of gut bacteria depleted in patients with multiple sclerosis

(2021) Samantha N. Jensen et al.   Science Advances

Dietary Effects of Anthocyanins in Human Health: A Comprehensive Review

(2021) Ana C. Gonçalves et al.   Pharmaceuticals

Prenylated isoflavones from the roots of Flemingia philippinensis as potential inhibitors of β-amyloid aggregation

(2021) Sheng-Li Niu et al.   FITOTERAPIA

The bioavailability of soy isoflavones in vitro and their effects on gut microbiota in the simulator of the human intestinal microbial ecosystem

(2021) Pin Chen et al.   FOOD RESEARCH INTERNATIONAL

Isoformononetin, a dietary isoflavone protects against streptozotocin induced rat model of neuroinflammation through inhibition of NLRP3/ASC/IL-1 axis activation

(2021) Swati Chaturvedi et al.   LIFE SCIENCES

Reversal of haloperidol-induced orofacial dyskinesia and neuroinflammation by isoflavones

(2021) Natália Fernandes Mezzomo et al.   MOLECULAR BIOLOGY REPORTS

The role of microbiota-gut-brain axis in neuropsychiatric and neurological disorders

(2021) Katarzyna Socała et al.   PHARMACOLOGICAL RESEARCH

Quercetin exhibits potent antioxidant activity, restores motor and non-motor deficits induced by rotenone toxicity

(2021) Syeda Madiha et al.   PLoS One

Dietary Regulation of Gut-Brain Axis in Alzheimer’s Disease: Importance of Microbiota Metabolites

(2021) Dulce M. Frausto et al.   Frontiers in Neuroscience

Role of Food Antioxidants in Modulating Gut Microbial Communities: Novel Understandings in Intestinal Oxidative Stress Damage and Their Impact on Host Health

(2021) Muhammad Shahid Riaz Rajoka et al.   Antioxidants

Quercetin and Baicalein Act as Potent Antiamyloidogenic and Fibril Destabilizing Agents for SOD1 Fibrils

(2020) Nidhi K. Bhatia et al.   ACS Chemical Neuroscience

Qi-activating quercetin alleviates mitochondrial dysfunction and neuroinflammation in vivo and in vitro

(2020) Sora Kang et al.   ARCHIVES OF PHARMACAL RESEARCH

Promising Polyphenols in Parkinson’s Disease Therapeutics

(2020) Ashish Singh et al.   NEUROCHEMICAL RESEARCH

The Efficacy and Safety of Ipriflavone in Postmenopausal Women with Osteopenia or Osteoporosis: A Systematic Review and Meta-analysis

(2020) Qinsheng Hu et al.   PHARMACOLOGICAL RESEARCH

Gut Microbiota, Its Role in Induction of Alzheimer’s Disease Pathology, and Possible Therapeutic Interventions: Special Focus on Anthocyanins

(2020) Muhammad Sohail Khan et al.   Cells

Hibiscus sabdariffa L.: A potent natural neuroprotective agent for the prevention of streptozotocin-induced Alzheimer’s disease in mice

(2020) Riham A. El-Shiekh et al.   BIOMEDICINE & PHARMACOTHERAPY

Targeting the microbiota in pharmacology of psychiatric disorders

(2020) Alessia Pascale et al.   PHARMACOLOGICAL RESEARCH

Protocatechuic Acid Extends Survival, Improves Motor Function, Diminishes Gliosis, and Sustains Neuromuscular Junctions in the hSOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis

(2020) Lilia A. Koza et al.   Nutrients

The recent failure of the PROMESA clinical trial for multiple system atrophy raises the question—are polyphenols a viable therapeutic option against proteinopathies?

(2020) Gal Bitan   Annals of Translational Medicine

Stabilization of delphinidin in a complex with sulfobutylether-β-cyclodextrin allows for antinociception in inflammatory pain

(2020) Reine-Solange Sauer et al.   ANTIOXIDANTS & REDOX SIGNALING

Genistein ameliorates inflammation and insulin resistance through mediation of gut microbiota composition in type 2 diabetic mice

(2020) Rui Yang et al.   EUROPEAN JOURNAL OF NUTRITION

Quercetin attenuates diabetic neuropathic pain by inhibiting mTOR/p70S6K pathway-mediated changes of synaptic morphology and synaptic protein levels in spinal dorsal horn of db/db mice

(2020) Ruiyao Wang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Genistein attenuates amyloid-beta-induced cognitive impairment in rats by modulation of hippocampal synaptotoxicity and hyperphosphorylation of Tau

(2020) Fernanda dos Santos Petry et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Gut microbiome in neuroendocrine and neuroimmune interactions: The case of genistein

(2020) Tai L. Guo et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Gut Microbiota Approach—A New Strategy to Treat Parkinson’s Disease

(2020) Jing Liu et al.   Frontiers in Cellular and Infection Microbiology

The Therapeutic Potential of Anthocyanins: Current Approaches Based on Their Molecular Mechanism of Action

(2020) Bahare Salehi et al.   Frontiers in Pharmacology

The Anti-Neuroinflammatory Role of Anthocyanins and Their Metabolites for the Prevention and Treatment of Brain Disorders

(2020) Joana F. Henriques et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Gut-Brain Axis: How Microbiota and Host Inflammasome Influence Brain Physiology and Pathology

(2020) Andrina Rutsch et al.   Frontiers in Immunology

Isolation of Neuroprotective Anthocyanins from Black Chokeberry (Aronia melanocarpa) against Amyloid-β-Induced Cognitive Impairment

(2020) Haichao Wen et al.   Foods

Quercetin‐3‐ O ‐Glucuronide Alleviates Cognitive Deficit and Toxicity in Aβ 1‐42 ‐Induced AD‐Like Mice and SH‐SY5Y Cells

(2020) Mengdai Xu et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Bioactivity of dietary polyphenols: The role of metabolites

(2019) Simon Vlad Luca et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

The Effect of a Pilot Dietary Intervention on Pain Outcomes in Patients Attending a Tertiary Pain Service

(2019) Katherine Brain et al.   Nutrients

Application of quercetin in neurological disorders: from nutrition to nanomedicine

(2019) Elnaz Amanzadeh et al.   REVIEWS IN THE NEUROSCIENCES

Neuroprotective benefits of grape seed and skin extract in a mouse model of Parkinson’s disease

(2019) Sarah Ben Youssef et al.   NUTRITIONAL NEUROSCIENCE

Natural Antioxidant Anthocyanins—A Hidden Therapeutic Candidate in Metabolic Disorders with Major Focus in Neurodegeneration

(2019) Ullah et al.   Nutrients

Neuroprotective Effects of Genistein in a SOD1-G93A Transgenic Mouse Model of Amyotrophic Lateral Sclerosis

(2019) Zichun Zhao et al.   Journal of Neuroimmune Pharmacology

Preventive Effect of Quercetin in a Triple Transgenic Alzheimer’s Disease Mice Model

(2019) Pérez-Corredor Paula et al.   MOLECULES

Liver Dysfunction as a Novel Player in Alzheimer’s Progression: Looking Outside the Brain

(2019) Lisbell D. Estrada et al.   Frontiers in Aging Neuroscience

Pain regulation by gut microbiota: molecular mechanisms and therapeutic potential

(2019) Ran Guo et al.   BRITISH JOURNAL OF ANAESTHESIA

The Gut Microbiota in Multiple Sclerosis: An Overview of Clinical Trials

(2019) Giovanni Schepici et al.   CELL TRANSPLANTATION

Safety and efficacy of epigallocatechin gallate in multiple system atrophy (PROMESA): a randomised, double-blind, placebo-controlled trial

(2019) Johannes Levin et al.   LANCET NEUROLOGY

The Microbiota-Gut-Brain Axis

(2019) John F. Cryan et al.   PHYSIOLOGICAL REVIEWS

Neuroprotective Effect of Quercetin in Combination with Piperine Against Rotenone- and Iron Supplement–Induced Parkinson’s Disease in Experimental Rats

(2019) Shakshi Sharma et al.   NEUROTOXICITY RESEARCH

Protective Effect of (−)Epigallocatechin-3-gallate on Rotenone-Induced Parkinsonism-like Symptoms in Rats

(2019) Hsiang-Chien Tseng et al.   NEUROTOXICITY RESEARCH

Combined therapies to treat complex diseases: The role of the gut microbiota in multiple sclerosis

(2018) Laura Calvo-Barreiro et al.   AUTOIMMUNITY REVIEWS

Flavonoid metabolism: the interaction of metabolites and gut microbiota

(2018) Kaeko Murota et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Insights into the intestinal bacterial metabolism of flavonoids and the bioactivities of their microbe-derived ring cleavage metabolites

(2018) Xinchi Feng et al.   DRUG METABOLISM REVIEWS

Anti-inflammatory effects of flavonoids in neurodegenerative disorders

(2018) Carmela Spagnuolo et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Regulation of redox status in neuronal SH-SY5Y cells by blueberry ( Vaccinium myrtillus L.) juice, cranberry ( Vaccinium macrocarpon A.) juice and cyanidin

(2018) Guillermo Cásedas et al.   FOOD AND CHEMICAL TOXICOLOGY

Genistein modulates the expression of Toll-like receptors in experimental autoimmune encephalomyelitis

(2018) Alyria Teixeira Dias et al.   INFLAMMATION RESEARCH

Anthocyanins as a potential pharmacological agent to manage memory deficit, oxidative stress and alterations in ion pump activity induced by experimental sporadic dementia of Alzheimer's type

(2018) Simone Muniz Pacheco et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Gut Microbiota in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis: Current Applications and Future Perspectives

(2018) Fengna Chu et al.   MEDIATORS OF INFLAMMATION

Anthocyanins Improve Hippocampus-Dependent Memory Function and Prevent Neurodegeneration via JNK/Akt/GSK3β Signaling in LPS-Treated Adult Mice

(2018) Muhammad Sohail Khan et al.   MOLECULAR NEUROBIOLOGY

A Review on the Weight-Loss Effects of Oxidized Tea Polyphenols

(2018) Dylan Rothenberg et al.   MOLECULES

Dietary polyphenols: A novel strategy to modulate microbiota-gut-brain axis

(2018) Diana Serra et al.   TRENDS IN FOOD SCIENCE & TECHNOLOGY

Body composition differences between adults with multiple sclerosis and BMI-matched controls without MS

(2018) Brooks C. Wingo et al.   Disability and Health Journal

Quercetin attenuates AZT-induced neuroinflammation in the CNS

(2018) Yi Yang et al.   Scientific Reports

Antioxidant and prebiotic activity of five peonidin-based anthocyanins extracted from purple sweet potato (Ipomoea batatas (L.) Lam.)

(2018) Hanju Sun et al.   Scientific Reports

Quercetin relieved diabetic neuropathic pain by inhibiting upregulated P2X4 receptor in dorsal root ganglia

(2018) Runan Yang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Neuroprotective effects of genistein on SH-SY5Y cells overexpressing A53T mutant α-synuclein

(2018) Sai Zhang et al.   Neural Regeneration Research

Gut microbiota modulation accounts for the neuroprotective properties of anthocyanins

(2018) Cláudia Marques et al.   Scientific Reports

Metabolism of anthocyanins and consequent effects on the gut microbiota

(2018) Lingmin Tian et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Calycosin attenuates MPTP-induced Parkinson's disease by suppressing the activation of TLR/NF-κB and MAPK pathways

(2018) Jing Yang et al.   PHYTOTHERAPY RESEARCH

Cuprizone-induced demyelination in the mouse hippocampus is alleviated by phytoestrogen genistein

(2018) Tomohiro Ohgomori et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Purple Corn Extract as Anti-allodynic Treatment for Trigeminal Pain: Role of Microglia

(2018) Giulia Magni et al.   Frontiers in Cellular Neuroscience

The Gut-Microglia Connection: Implications for Central Nervous System Diseases

(2018) Yiliang Wang et al.   Frontiers in Immunology

Malvidin attenuates pain and inflammation in rats with osteoarthritis by suppressing NF-κB signaling pathway

(2017) Teng Dai et al.   INFLAMMATION RESEARCH

Effect of the oral administration of nanoencapsulated quercetin on a mouse model of Alzheimer’s disease

(2017) Lina Clara Gayoso e Ibiapina Moreno et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Natural Dietary Supplementation of Anthocyanins via PI3K/Akt/Nrf2/HO-1 Pathways Mitigate Oxidative Stress, Neurodegeneration, and Memory Impairment in a Mouse Model of Alzheimer’s Disease

(2017) Tahir Ali et al.   MOLECULAR NEUROBIOLOGY

Enhanced neuroprotection of anthocyanin-loaded PEG-gold nanoparticles against Aβ 1-42 -induced neuroinflammation and neurodegeneration via the NF- K B /JNK/GSK3β signaling pathway

(2017) Min Ju Kim et al.   Nanomedicine-Nanotechnology Biology and Medicine

The “Gut Feeling”: Breaking Down the Role of Gut Microbiome in Multiple Sclerosis

(2017) Samantha N. Freedman et al.   Neurotherapeutics

Black Raspberries and Their Anthocyanin and Fiber Fractions Alter the Composition and Diversity of Gut Microbiota in F-344 Rats

(2017) Pan Pan et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

An anthocyanin-enriched extract from strawberries delays disease onset and extends survival in the hSOD1G93A mouse model of amyotrophic lateral sclerosis

(2017) Aimee N. Winter et al.   NUTRITIONAL NEUROSCIENCE

Quercitrin and quercetin 3-β-d-glucoside as chemical chaperones for the A4V SOD1 ALS-causing mutant

(2017) Philbert Ip et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Neuroprotective effect of ipriflavone against scopolamine-induced memory impairment in rats

(2017) Hani S. Hafez et al.   PSYCHOPHARMACOLOGY

The roles of epigallocatechin-3-gallate in the treatment of neuropathic pain: an update on preclinical in vivo studies and future perspectives

(2017) Sabrina Bimonte et al.   Drug Design Development and Therapy

16S rRNA Next Generation Sequencing Analysis Shows Bacteria in Alzheimer’s Post-Mortem Brain

(2017) David C. Emery et al.   Frontiers in Aging Neuroscience

Anthocyanins encapsulated by PLGA@PEG nanoparticles potentially improved its free radical scavenging capabilities via p38/JNK pathway against Aβ1–42-induced oxidative stress

(2017) Faiz Ul Amin et al.   JOURNAL OF NANOBIOTECHNOLOGY

Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease

(2016) Timothy R. Sampson et al.   CELL

The Modulatory Effect of Anthocyanins from Purple Sweet Potato on Human Intestinal Microbiota in Vitro

(2016) Xin Zhang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Gut instincts: microbiota as a key regulator of brain development, ageing and neurodegeneration

(2016) Timothy G. Dinan et al.   JOURNAL OF PHYSIOLOGY-LONDON

Anthocyanin-Loaded PEG-Gold Nanoparticles Enhanced the Neuroprotection of Anthocyanins in an Aβ1–42 Mouse Model of Alzheimer’s Disease

(2016) Tahir Ali et al.   MOLECULAR NEUROBIOLOGY

Understanding the mechanisms of faecal microbiota transplantation

(2016) Alexander Khoruts et al.   Nature Reviews Gastroenterology & Hepatology

Anthocyanins protect against LPS-induced oxidative stress-mediated neuroinflammation and neurodegeneration in the adult mouse cortex

(2016) Muhammad Sohail Khan et al.   NEUROCHEMISTRY INTERNATIONAL

Probiotics and prebiotic fiber for constipation associated with Parkinson disease

(2016) Michela Barichella et al.   NEUROLOGY

Mechanisms of Neuroprotection by Quercetin: Counteracting Oxidative Stress and More

(2016) Lucio G. Costa et al.   Oxidative Medicine and Cellular Longevity

(-)-Epigallocatechin-3-Gallate Antihyperalgesic Effect Associates With Reduced CX3CL1 Chemokine Expression in Spinal Cord

(2016) Marc Bosch-Mola et al.   PHYTOTHERAPY RESEARCH

The biological activities, chemical stability, metabolism and delivery systems of quercetin: A review

(2016) Weiyou Wang et al.   TRENDS IN FOOD SCIENCE & TECHNOLOGY

Metabolic response to epigallocatechin-3-gallate in relapsing-remitting multiple sclerosis: a randomized clinical trial

(2015) Anja Mähler et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Classification, diagnosis, and differential diagnosis of multiple sclerosis

(2015) Ilana Katz Sand   CURRENT OPINION IN NEUROLOGY

Interaction of dietary compounds, especially polyphenols, with the intestinal microbiota: a review

(2015) Aleksandra Duda-Chodak et al.   EUROPEAN JOURNAL OF NUTRITION

Anthocyanins suppress the secretion of proinflammatory mediators and oxidative stress, and restore ion pump activities in demyelination

(2015) Fabiano B. Carvalho et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

The impact of chronic blackberry intake on the neuroinflammatory status of rats fed a standard or high-fat diet

(2015) Manuela Meireles et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Endogenous and exogenous mediators of quercetin bioavailability

(2015) Yi Guo et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Collective unconscious: How gut microbes shape human behavior

(2015) Timothy G. Dinan et al.   JOURNAL OF PSYCHIATRIC RESEARCH

MDS research criteria for prodromal Parkinson's disease

(2015) Daniela Berg et al.   MOVEMENT DISORDERS

Protective effects of Anthocyanins against Amyloid beta-induced neurotoxicity in vivo and in vitro

(2015) Haroon Badshah et al.   NEUROCHEMISTRY INTERNATIONAL

Modulation of BV-2 microglia functions by novel quercetin pivaloyl ester

(2015) Nataša Mrvová et al.   NEUROCHEMISTRY INTERNATIONAL

The flavonoid quercetin ameliorates Alzheimer's disease pathology and protects cognitive and emotional function in aged triple transgenic Alzheimer's disease model mice

(2015) Angélica Maria Sabogal-Guáqueta et al.   NEUROPHARMACOLOGY

Anthocyanin suppresses the toxicity of Aβ deposits through diversion of molecular forms inin vitroandin vivomodels of Alzheimer's disease

(2015) Miho Yoshida Yamakawa et al.   NUTRITIONAL NEUROSCIENCE

Isolation and characterization of rat intestinal bacteria involved in biotransformation of (−)-epigallocatechin

(2014) Akiko Takagaki et al.   ARCHIVES OF MICROBIOLOGY

Neuroprotective effects of anthocyanin- and proanthocyanidin-rich extracts in cellular models of Parkinson׳s disease

(2014) Katherine E. Strathearn et al.   BRAIN RESEARCH

Anthocyanins Protect against Kainic Acid-induced Excitotoxicity and Apoptosis via ROS-activated AMPK Pathway in Hippocampal Neurons

(2014) Ikram Ullah et al.   CNS Neuroscience & Therapeutics

Bioavailability of anthocyanins

(2014) Jim Fang   DRUG METABOLISM REVIEWS

Antimutagenic activity of ipriflavone against the DNA-damage induced by cyclophosphamide in mice

(2014) Juliana Macedo Delarmelina et al.   FOOD AND CHEMICAL TOXICOLOGY

Formation of α-synuclein Lewy neurite–like aggregates in axons impedes the transport of distinct endosomes

(2014) Laura A. Volpicelli-Daley et al.   MOLECULAR BIOLOGY OF THE CELL

Immune modulation of the brain-gut-microbe axis

(2014) Sahar El Aidy et al.   Frontiers in Microbiology

Human metabolism and elimination of the anthocyanin, cyanidin-3-glucoside: a 13C-tracer study

(2013) Charles Czank et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Transport Mechanisms for Soy Isoflavones and Microbial Metabolites Dihydrogenistein and Dihydrodaidzein Across Monolayers and Membranes

(2013) Shoko KOBAYASHI et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

The Case for Anthocyanin Consumption to Promote Human Health: A Review

(2013) Elisa Pojer et al.   COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY

The neuroprotective effects of ipriflavone against H2O2 and amyloid beta induced toxicity in human neuroblastoma SH-SY5Y cells

(2013) Zhimin Xiao et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Novel immunoregulatory properties of EGCG on reducing inflammation in EAE

(2013) Hong Nie   Frontiers in Bioscience-Landmark

Anthocyanins restore behavioral and biochemical changes caused by streptozotocin-induced sporadic dementia of Alzheimer's type

(2013) Jessié M. Gutierres et al.   LIFE SCIENCES

The antioxidant activity of daidzein metabolites, O-desmethylangolensin and equol, in HepG2 cells

(2013) EUN JEONG CHOI et al.   Molecular Medicine Reports

Anthocyanins Protect Against Ethanol-Induced Neuronal Apoptosis via GABAB1 Receptors Intracellular Signaling in Prenatal Rat Hippocampal Neurons

(2013) Shahid ali Shah et al.   MOLECULAR NEUROBIOLOGY

Absorption and metabolism of proanthocyanidins

(2013) Keqin Ou et al.   Journal of Functional Foods

Bioavailability of anthocyanins and derivatives

(2013) Iva Fernandes et al.   Journal of Functional Foods

Anthocyanins

(2012) Beverley J. Glover et al.   CURRENT BIOLOGY

Comparison of vaginal gel isoflavones versus no topical treatment in vaginal dystrophy: results of a preliminary prospective study

(2012) Cristina Tedeschi et al.   GYNECOLOGICAL ENDOCRINOLOGY

Metabolism of Anthocyanins by Human Gut Microflora and Their Influence on Gut Bacterial Growth

(2012) Maria Hidalgo et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Brain-Targeted Proanthocyanidin Metabolites for Alzheimer's Disease Treatment

(2012) J. Wang et al.   JOURNAL OF NEUROSCIENCE

Anthocyanin-enriched bilberry and blackcurrant extracts modulate amyloid precursor protein processing and alleviate behavioral abnormalities in the APP/PS1 mouse model of Alzheimer's disease

(2012) Saila Vepsäläinen et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

A Pilot Study on the Effects of S-Equol Compared to Soy Isoflavones on Menopausal Hot Flash Frequency

(2012) Belinda H. Jenks et al.   JOURNAL OF WOMENS HEALTH

The microbiome-gut-brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner

(2012) G Clarke et al.   MOLECULAR PSYCHIATRY

Gut microbiota composition correlates with diet and health in the elderly

(2012) Marcus J. Claesson et al.   NATURE

Habitual intake of dietary flavonoids and risk of Parkinson disease

(2012) X. Gao et al.   NEUROLOGY

Dietary anthocyanin-rich plants: Biochemical basis and recent progress in health benefits studies

(2011) Takanori Tsuda   MOLECULAR NUTRITION & FOOD RESEARCH

Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination

(2011) Kerstin Berer et al.   NATURE

Neuroprotective effect of cyanidin-3-O-glucoside anthocyanin in mice with focal cerebral ischemia

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Mulberry fruit protects dopaminergic neurons in toxin-induced Parkinson's disease models

(2010) Hyo Geun Kim et al.   BRITISH JOURNAL OF NUTRITION

Protective effect of panaxatriol saponins extracted from Panax notoginseng against MPTP-induced neurotoxicity in vivo

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Mucopolysaccharidosis type IIIB may predominantly present with an attenuated clinical phenotype

(2010) Marlies J. Valstar et al.   JOURNAL OF INHERITED METABOLIC DISEASE

The effect of dietary soy supplementation compared to estrogen and placebo on menopausal symptoms: A randomized controlled trial

(2010) Lucio O. Carmignani et al.   MATURITAS

Soy Isoflavones in Conjunction With Radiation Therapy in Patients With Prostate Cancer

(2010) Iftekhar U. Ahmad et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Insights into the metabolism and microbial biotransformation of dietary flavan-3-ols and the bioactivity of their metabolites

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Anthocyanin Content, Lipid Peroxidation and Cyclooxygenase Enzyme Inhibitory Activities of Sweet and Sour Cherries

(2009) Vanisree Mulabagal et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Antioxidant and cognitive promotion effects of anthocyanin-rich mulberry (Morus atropurpurea L.) on senescence-accelerated mice and prevention of Alzheimer's disease

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