Insights into the intestinal bacterial metabolism of flavonoids and the bioactivities of their microbe-derived ring cleavage metabolites

Biotransformation and metabolism of three mulberry anthocyanin monomers by rat gut microflora

(2017) Yao Chen et al.   FOOD CHEMISTRY

The role of metabolism (and the microbiome) in defining the clinical efficacy of dietary flavonoids

(2016) Aedín Cassidy et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Exploring the Colonic Metabolism of Grape and Strawberry Anthocyanins and Their in Vitro Apoptotic Effects in HT-29 Colon Cancer Cells

(2016) María-Carmen López de las Hazas et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

The Modulatory Effect of Anthocyanins from Purple Sweet Potato on Human Intestinal Microbiota in Vitro

(2016) Xin Zhang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

3,4-Dihydroxyphenylacetic acid, a microbiota-derived metabolite of quercetin, attenuates acetaminophen (APAP)-induced liver injury through activation of Nrf-2

(2016) Huiting Xue et al.   XENOBIOTICA

Fate of Microbial Metabolites of Dietary Polyphenols in Rats: Is the Brain Their Target Destination?

(2015) Mattia Gasperotti et al.   ACS Chemical Neuroscience

Taxifolin curbs NF-κB-mediated Wnt/β-catenin signaling via up-regulating Nrf2 pathway in experimental colon carcinogenesis

(2015) Krishnan Manigandan et al.   BIOCHIMIE

High gastrointestinal permeability and local metabolism of naringenin: influence of antibiotic treatment on absorption and metabolism

(2015) Naiara Orrego-Lagarón et al.   BRITISH JOURNAL OF NUTRITION

Interaction of dietary compounds, especially polyphenols, with the intestinal microbiota: a review

(2015) Aleksandra Duda-Chodak et al.   EUROPEAN JOURNAL OF NUTRITION

3,4-dihydroxyphenylacetic acid, a microbiota-derived metabolite of quercetin, protects against pancreatic β-cells dysfunction induced by high cholesterol

(2015) Catalina Carrasco-Pozo et al.   EXPERIMENTAL CELL RESEARCH

New insights into the bioavailability of red raspberry anthocyanins and ellagitannins

(2015) Iziar A. Ludwig et al.   FREE RADICAL BIOLOGY AND MEDICINE

Effects of Metabolites Produced from (−)-Epigallocatechin Gallate by Rat Intestinal Bacteria on Angiotensin I-Converting Enzyme Activity and Blood Pressure in Spontaneously Hypertensive Rats

(2015) Akiko Takagaki et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Isolation and characterization of human intestinalEnterococcus aviumEFEL009 converting rutin to quercetin

(2015) N.R. Shin et al.   LETTERS IN APPLIED MICROBIOLOGY

3,4-Dihydroxytoluene, a metabolite of rutin, inhibits inflammatory responses in lipopolysaccharide-activated macrophages by reducing the activation of NF-κB signaling

(2014) Kang-Yi Su et al.   BMC Complementary and Alternative Medicine

Antibacterial Activities of Flavonoids: Structure-Activity Relationship and Mechanism

(2014) Yixi Xie et al.   CURRENT MEDICINAL CHEMISTRY

Flavonoids for Allergic Diseases: Present Evidence and Future Perspective

(2014) Toshio Tanaka   CURRENT PHARMACEUTICAL DESIGN

Microbial phenolic metabolites improve glucose-stimulated insulin secretion and protect pancreatic beta cells against tert-butyl hydroperoxide-induced toxicity via ERKs and PKC pathways

(2014) Elisa Fernández-Millán et al.   FOOD AND CHEMICAL TOXICOLOGY

Metabolism of Kaempferia parviflora Polymethoxyflavones by Human Intestinal Bacterium Bautia sp. MRG-PMF1

(2014) Mihyang Kim et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Interplay between Anthocyanins and Gut Microbiota

(2014) Ana Faria et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Development of a targeted method for twenty-three metabolites related to polyphenol gut microbial metabolism in biological samples, using SPE and UHPLC–ESI-MS/MS

(2014) Mattia Gasperotti et al.   TALANTA

Metabolism of Dietary Flavonoids in Liver Microsomes

(2013) Jianbo Xiao et al.   CURRENT DRUG METABOLISM

The antioxidant activity of daidzein metabolites, O-desmethylangolensin and equol, in HepG2 cells

(2013) EUN JEONG CHOI et al.   Molecular Medicine Reports

Chemistry and Biological Activities of Flavonoids: An Overview

(2013) Shashank Kumar et al.   TheScientificWorldJOURNAL

Flavonoid Bioavailability and Attempts for Bioavailability Enhancement

(2013) Surangi Thilakarathna et al.   Nutrients

Changes in the intestinal microbiota from adulthood through to old age

(2012) P.W. O'Toole   CLINICAL MICROBIOLOGY AND INFECTION

Dihydroquercetin: More than just an impurity?

(2012) Anita Elaine Weidmann   EUROPEAN JOURNAL OF PHARMACOLOGY

The anthocyanin metabolites gallic acid, 3-O-methylgallic acid, and 2,4,6-trihydroxybenzaldehyde decrease human colon cancer cell viability by regulating pro-oncogenic signals

(2012) Sarah C. Forester et al.   MOLECULAR CARCINOGENESIS

The role of the gut microbiota in nutrition and health

(2012) Harry J. Flint et al.   Nature Reviews Gastroenterology & Hepatology

A state-of-the-art overview of the effect of metabolic conjugation on the biological activity of flavonoids

(2012) Karsten Beekmann et al.   Food & Function

Comparison of the Effects of Antimicrobial Agents from Three Different Classes on Metabolism of Isoflavonoids by Colonic Microflora Using Etest Strips

(2011) John B. Sutherland et al.   CURRENT MICROBIOLOGY

Colonic Catabolism of Ellagitannins, Ellagic Acid, and Raspberry Anthocyanins: In Vivo and In Vitro Studies

(2011) R. Gonzalez-Barrio et al.   DRUG METABOLISM AND DISPOSITION

Metabolic pathways of the colonic metabolism of flavonoids (flavonols, flavones and flavanones) and phenolic acids

(2011) Aida Serra et al.   FOOD CHEMISTRY

Daidzein and Genistein Are Converted to Equol and 5-Hydroxy-Equol by Human Intestinal Slackia isoflavoniconvertens in Gnotobiotic Rats

(2011) Anastasia Matthies et al.   JOURNAL OF NUTRITION

Gut Metabolites of Anthocyanins, Gallic Acid, 3-O-Methylgallic Acid, and 2,4,6-Trihydroxybenzaldehyde, Inhibit Cell Proliferation of Caco-2 Cells

(2010) Sarah C. Forester et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

In Vitro Bioconversion of Polyphenols from Black Tea and Red Wine/Grape Juice by Human Intestinal Microbiota Displays Strong Interindividual Variability

(2010) Gabriele Gross et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Equol: History, Chemistry, and Formation

(2010) Kenneth D. R. Setchell et al.   JOURNAL OF NUTRITION

Recovery and metabolism of xanthohumol in germ-free and human microbiota-associated rats

(2010) Laura Hanske et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Protocatechuic acid inhibits neurotoxicity induced by MPTP in vivo

(2010) Hong-Ning Zhang et al.   NEUROSCIENCE LETTERS

Flavonoids as anti-inflammatory agents

(2010) Mauro Serafini et al.   PROCEEDINGS OF THE NUTRITION SOCIETY

Dihydroxylated phenolic acids derived from microbial metabolism reduce lipopolysaccharide-stimulated cytokine secretion by human peripheral blood mononuclear cells

(2009) María Monagas et al.   BRITISH JOURNAL OF NUTRITION

Protective effects of flavonoids and two metabolites against oxidative stress in neuronal PC12 cells

(2009) Sanja Pavlica et al.   LIFE SCIENCES

Polyphenol metabolites from colonic microbiota exert anti-inflammatory activity on different inflammation models

(2009) Mar Larrosa et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Microbial metabolism of soy isoflavones by human intestinal bacterial strains

(2008) Ryota Tsuchihashi et al.   Journal of Natural Medicines

Inhibition of histone-deacetylase activity by short-chain fatty acids and some polyphenol metabolites formed in the colon

(2008) Markus Waldecker et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY