Microbial-derived metabolites as a risk factor of age-related cognitive decline and dementia
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Title
Microbial-derived metabolites as a risk factor of age-related cognitive decline and dementia
Authors
Keywords
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Journal
Molecular Neurodegeneration
Volume 17, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2022-06-17
DOI
10.1186/s13024-022-00548-6
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Note: Only part of the references are listed.- Role of Microbiota-Gut-Brain Axis in Regulating Dopaminergic Signaling
- (2022) Sevag Hamamah et al. Biomedicines
- Neuronal Mitophagy: Friend or Foe?
- (2021) Christina Doxaki et al. Frontiers in Cell and Developmental Biology
- Age-related cognitive decline is associated with microbiota-gut-brain axis disorders and neuroinflammation in mice
- (2021) Mei-Ling Wu et al. BEHAVIOURAL BRAIN RESEARCH
- Going with the grain: Fiber, cognition, and the microbiota-gut-brain-axis
- (2021) Kirsten Berding et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- Mining Microbes for Mental Health: Determining the Role of Microbial Metabolic Pathways in Human Brain Health and Disease
- (2021) Simon Spichak et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- Impaired eIF5A function causes a Mendelian disorder that is partially rescued in model systems by spermidine
- (2021) Víctor Faundes et al. Nature Communications
- Mitochondrial Dysfunction and Oxidative Stress in Alzheimer’s Disease
- (2021) Afzal Misrani et al. Frontiers in Aging Neuroscience
- Structural and Functional Dysbiosis of Fecal Microbiota in Chinese Patients With Alzheimer's Disease
- (2021) Zongxin Ling et al. Frontiers in Cell and Developmental Biology
- Diet quality, gut microbiota, and microRNAs associated with mild cognitive impairment in middle-aged and elderly Chinese population
- (2021) Xiaona Zhang et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Can Natural Products Exert Neuroprotection without Crossing the Blood–Brain Barrier?
- (2021) Manon Leclerc et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Untargeted Stable Isotope Probing of the Gut Microbiota Metabolome Using 13C-Labeled Dietary Fibers
- (2021) Pan Deng et al. JOURNAL OF PROTEOME RESEARCH
- Dietary spermidine improves cognitive function
- (2021) Sabrina Schroeder et al. Cell Reports
- Microbiota-derived short chain fatty acids modulate microglia and promote Aβ plaque deposition
- (2021) Alessio Vittorio Colombo et al. eLife
- Plasma TMAO increase after healthy diets: results from 2 randomized controlled trials with dietary fish, polyphenols, and whole-grain cereals
- (2021) Giuseppina Costabile et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Tryptophan-metabolizing gut microbes regulate adult neurogenesis via the aryl hydrocarbon receptor
- (2021) George Zhang Wei et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- In vivo and neuropathology data support locus coeruleus integrity as indicator of Alzheimer’s disease pathology and cognitive decline
- (2021) Heidi I. L. Jacobs et al. Science Translational Medicine
- Review: microbial transformations of human bile acids
- (2021) Douglas V. Guzior et al. Microbiome
- Neuroinflammation and the Kynurenine Pathway in CNS Disease: Molecular Mechanisms and Therapeutic Implications
- (2021) Mustafa N. Mithaiwala et al. Cells
- Association of small intestinal bacterial overgrowth with nonalcoholic fatty liver disease in children: A meta-analysis
- (2021) Linghan Kuang et al. PLoS One
- Regulation of blood–brain barrier integrity by microbiome-associated methylamines and cognition by trimethylamine N-oxide
- (2021) Lesley Hoyles et al. Microbiome
- Concomitant memantine and Lactobacillus plantarum treatment attenuates cognitive impairments in APP/PS1 mice
- (2020) Qiu-Jun Wang et al. Aging-US
- Spermidine in dementia
- (2020) Thomas Pekar et al. WIENER KLINISCHE WOCHENSCHRIFT
- Spermidine and spermine delay brain aging by inducing autophagy in SAMP8 mice
- (2020) Ting-Ting Xu et al. Aging-US
- Aryl Hydrocarbon Receptor in Post-Mortem Hippocampus and in Serum from Young, Elder, and Alzheimer’s Patients
- (2020) Nicte Alaide Ramos-García et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Gut‐brain axis serotonergic responses to acute stress exposure are microbiome‐dependent
- (2020) Joshua M. Lyte et al. NEUROGASTROENTEROLOGY AND MOTILITY
- Role of Gut Microbiota in Neuroendocrine Regulation of Carbohydrate and Lipid Metabolism via the Microbiota-Gut-Brain-Liver Axis
- (2020) Shu-Zhi Wang et al. Microorganisms
- Developmental Signatures of Microbiota-Derived Metabolites in the Mouse Brain
- (2020) Jonathan R. Swann et al. Metabolites
- P-cresol Alters Brain Dopamine Metabolism and Exacerbates Autism-Like Behaviors in the BTBR Mouse
- (2020) Tiziana Pascucci et al. Brain Sciences
- Mechanisms by which autophagy regulates memory capacity in ageing
- (2020) Maria De Risi et al. AGING CELL
- Microbial Imidazole Propionate Affects Responses to Metformin through p38γ-Dependent Inhibitory AMPK Phosphorylation
- (2020) Ara Koh et al. Cell Metabolism
- Dementia prevention, intervention, and care: 2020 report of the Lancet Commission
- (2020) Gill Livingston et al. LANCET
- Gut Metabolite TMAO Induces Synaptic Plasticity Deficits by Promoting Endoplasmic Reticulum Stress
- (2020) Manoj Govindarajulu et al. Frontiers in Molecular Neuroscience
- Microbiome definition re-visited: old concepts and new challenges
- (2020) Gabriele Berg et al. Microbiome
- Increase in blood–brain barrier leakage in healthy, older adults
- (2020) Inge C. M. Verheggen et al. GeroScience
- ROS Generation in Microglia: Understanding Oxidative Stress and Inflammation in Neurodegenerative Disease
- (2020) Dominic S. A. Simpson et al. Antioxidants
- p-Cresol Sulfate Caused Behavior Disorders and Neurodegeneration in Mice with Unilateral Nephrectomy Involving Oxidative Stress and Neuroinflammation
- (2020) Chiao-Yin Sun et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Short-Chain Fatty Acids and Lipopolysaccharide as Mediators Between Gut Dysbiosis and Amyloid Pathology in Alzheimer’s Disease
- (2020) Moira Marizzoni et al. JOURNAL OF ALZHEIMERS DISEASE
- Gut Microbiota and Dysbiosis in Alzheimer’s Disease: Implications for Pathogenesis and Treatment
- (2020) Shan Liu et al. MOLECULAR NEUROBIOLOGY
- Gut microbial metabolites as multi-kingdom intermediates
- (2020) Kimberly A. Krautkramer et al. NATURE REVIEWS MICROBIOLOGY
- Gut microbial molecules in behavioural and neurodegenerative conditions
- (2020) Brittany D. Needham et al. NATURE REVIEWS NEUROSCIENCE
- Trimethylamine N-Oxide, a Gut Microbiota-Dependent Metabolite, is Associated with Frailty in Older Adults with Cardiovascular Disease
- (2020) Wei He et al. Clinical Interventions in Aging
- Gut mycobiome and its interaction with diet, gut bacteria and alzheimer's disease markers in subjects with mild cognitive impairment: A pilot study
- (2020) Ravinder Nagpal et al. EBioMedicine
- The gut microbiome–derived metabolite trimethylamine N-oxide modulates neuroinflammation and cognitive function with aging
- (2020) Vienna E. Brunt et al. GeroScience
- Results from a pilot study: The effects of nicotinamide riboside on mild cognitive impairment
- (2020) Miranda E. Orr et al. Alzheimers & Dementia
- Nutraceutical Approaches of Autophagy and Neuroinflammation in Alzheimer’s Disease: A Systematic Review
- (2020) Reinhard Gruendler et al. MOLECULES
- The positive effect of spermidine in older adults suffering from dementia
- (2020) Thomas Pekar et al. WIENER KLINISCHE WOCHENSCHRIFT
- Imidazole propionate is increased in diabetes and associated with dietary patterns and altered microbial ecology
- (2020) Antonio Molinaro et al. Nature Communications
- Urinary metabolic phenotyping for Alzheimer’s disease
- (2020) Natalja Kurbatova et al. Scientific Reports
- Blood–Brain Barrier Leakage Is Increased in Parkinson’s Disease
- (2020) Sarah Al-Bachari et al. Frontiers in Physiology
- Gut bacterial tyrosine decarboxylases restrict levels of levodopa in the treatment of Parkinson’s disease
- (2019) Sebastiaan P. van Kessel et al. Nature Communications
- The Relationships Between Vitamin K and Cognition: A Review of Current Evidence
- (2019) Ludovico Alisi et al. Frontiers in Neurology
- Gut Microbe to Brain Signaling: What Happens in Vagus…
- (2019) Christine Fülling et al. NEURON
- The Role of Gut Microbiota in Pathogenesis of Alzheimer's Disease
- (2019) Mehmet Bostanciklioğlu JOURNAL OF APPLIED MICROBIOLOGY
- Altered microbiomes distinguish Alzheimer’s disease from amnestic mild cognitive impairment and health in a Chinese cohort
- (2019) Ping Liu et al. BRAIN BEHAVIOR AND IMMUNITY
- Polyamines and eIF5A Hypusination Modulate Mitochondrial Respiration and Macrophage Activation
- (2019) Daniel J. Puleston et al. Cell Metabolism
- APOE genotype influences the gut microbiome structure and function in humans and mice: relevance for Alzheimer’s disease pathophysiology
- (2019) Tam T. T. Tran et al. FASEB JOURNAL
- Epigenetic mechanisms related to cognitive decline during aging
- (2019) María F. Harman et al. JOURNAL OF NEUROSCIENCE RESEARCH
- The kynurenine pathway: a finger in every pie
- (2019) Jonathan Savitz MOLECULAR PSYCHIATRY
- Alzheimer’s Disease Microbiome Is Associated with Dysregulation of the Anti-Inflammatory P-Glycoprotein Pathway
- (2019) John P. Haran et al. mBio
- Effects of spermidine supplementation on cognition and biomarkers in older adults with subjective cognitive decline (SmartAge)—study protocol for a randomized controlled trial
- (2019) Miranka Wirth et al. Alzheimers Research & Therapy
- Tryptophan Metabolic Pathways and Brain Serotonergic Activity: A Comparative Review
- (2019) Erik Höglund et al. Frontiers in Endocrinology
- Alzheimer’s disease: pathogenesis, diagnostics, and therapeutics
- (2019) Sneham Tiwari et al. International Journal of Nanomedicine
- Role of Tryptophan in Microbiota-Induced Depressive-Like Behavior: Evidence From Tryptophan Depletion Study
- (2019) Iva Lukić et al. Frontiers in Behavioral Neuroscience
- Mild cognitive impairment has similar alterations as Alzheimer's disease in gut microbiota
- (2019) Binyin Li et al. Alzheimers & Dementia
- Exploratory analysis of covariation of microbiota-derived vitamin K and cognition in older adults
- (2019) Angela McCann et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Higher Circulating Trimethylamine N-oxide Sensitizes Sevoflurane-Induced Cognitive Dysfunction in Aged Rats Probably by Downregulating Hippocampal Methionine Sulfoxide Reductase A
- (2019) Liang Zhao et al. NEUROCHEMICAL RESEARCH
- Association of plasma trimethylamine-N-oxide levels with post-stroke cognitive impairment: a 1-year longitudinal study
- (2019) Chen Zhu et al. NEUROLOGICAL SCIENCES
- The Microbiota-Gut-Brain Axis
- (2019) John F. Cryan et al. PHYSIOLOGICAL REVIEWS
- Gut microbes and metabolites as modulators of blood-brain barrier integrity and brain health
- (2019) Aimée Parker et al. Gut Microbes
- Decreased levels of circulating trimethylamine N-oxide alleviate cognitive and pathological deterioration in transgenic mice: a potential therapeutic approach for Alzheimer’s disease
- (2019) Qiang Gao et al. Aging-US
- Higher cerebrospinal fluid to plasma ratio of p-cresol sulfate and indoxyl sulfate in patients with Parkinson’s disease
- (2019) Bartłomiej Sankowski et al. CLINICA CHIMICA ACTA
- Decreased plasmatic spermidine and increased spermine in mild cognitive impairment and Alzheimer’s disease patients
- (2019) HELENA P. G. JOAQUIM et al. Archives of Clinical Psychiatry
- Interplay between the human gut microbiome and host metabolism
- (2019) Alessia Visconti et al. Nature Communications
- The relationship between the gut microbiome and mild cognitive impairment in patients without dementia: a cross-sectional study conducted in Japan
- (2019) Naoki Saji et al. Scientific Reports
- Spermidine protects from age-related synaptic alterations at hippocampal mossy fiber-CA3 synapses
- (2019) Marta Maglione et al. Scientific Reports
- Trimethylamine-N -oxide promotes brain aging and cognitive impairment in mice
- (2018) Dang Li et al. AGING CELL
- Safety and tolerability of spermidine supplementation in mice and older adults with subjective cognitive decline
- (2018) Claudia Schwarz et al. Aging-US
- The cholinergic system in the pathophysiology and treatment of Alzheimer’s disease
- (2018) Harald Hampel et al. BRAIN
- Sodium butyrate abolishes lipopolysaccharide-induced depression-like behaviors and hippocampal microglial activation in mice
- (2018) Yosuke Yamawaki et al. BRAIN RESEARCH
- Neurotransmitter modulation by the gut microbiota
- (2018) Philip Strandwitz BRAIN RESEARCH
- Gut Microbiota Regulation of Tryptophan Metabolism in Health and Disease
- (2018) Allison Agus et al. Cell Host & Microbe
- A randomized controlled trial on the efficacy of resistant dextrin, as functional food, in women with type 2 diabetes: Targeting the hypothalamic–pituitary–adrenal axis and immune system
- (2018) Mahdieh Abbasalizad Farhangi et al. CLINICAL NUTRITION
- Dysregulated bile acid synthesis and dysbiosis are implicated in Western diet–induced systemic inflammation, microglial activation, and reduced neuroplasticity
- (2018) Prasant Kumar Jena et al. FASEB JOURNAL
- Protein-bounded uremic toxin p-cresylsulfate induces vascular permeability alternations
- (2018) Wei-Hua Tang et al. HISTOCHEMISTRY AND CELL BIOLOGY
- Aryl Hydrocarbon Receptor Activation Modulates Intestinal Epithelial Barrier Function by Maintaining Tight Junction Integrity
- (2018) Min Yu et al. International Journal of Biological Sciences
- Vascular Cognitive Impairment and the Gut Microbiota
- (2018) Sinian Li et al. JOURNAL OF ALZHEIMERS DISEASE
- Gut Microbiota is Altered in Patients with Alzheimer’s Disease
- (2018) Zhen-Qian Zhuang et al. JOURNAL OF ALZHEIMERS DISEASE
- The Gut Microbiome Alterations and Inflammation-Driven Pathogenesis of Alzheimer’s Disease—a Critical Review
- (2018) Marta Sochocka et al. MOLECULAR NEUROBIOLOGY
- Blood–brain barrier breakdown in Alzheimer disease and other neurodegenerative disorders
- (2018) Melanie D. Sweeney et al. Nature Reviews Neurology
- Sodium butyrate triggers a functional elongation of microglial process via Akt-small RhoGTPase activation and HDACs inhibition
- (2018) Peng Wang et al. NEUROBIOLOGY OF DISEASE
- Phenyl sulfate, indoxyl sulfate and p-cresyl sulfate decrease glutathione level to render cells vulnerable to oxidative stress in renal tubular cells
- (2018) Takeo Edamatsu et al. PLoS One
- Spermidine in health and disease
- (2018) Frank Madeo et al. SCIENCE
- Vitamin K Deficiency Induced by Warfarin Is Associated With Cognitive and Behavioral Perturbations, and Alterations in Brain Sphingolipids in Rats
- (2018) Sahar Tamadon-Nejad et al. Frontiers in Aging Neuroscience
- Impact of the Gut Microbiota on Intestinal Immunity Mediated by Tryptophan Metabolism
- (2018) Jing Gao et al. Frontiers in Cellular and Infection Microbiology
- The Vagus Nerve at the Interface of the Microbiota-Gut-Brain Axis
- (2018) Bruno Bonaz et al. Frontiers in Neuroscience
- Neurally Released GABA Acts via GABAC Receptors to Modulate Ca2+ Transients Evoked by Trains of Synaptic Inputs, but Not Responses Evoked by Single Stimuli, in Myenteric Neurons of Mouse Ileum
- (2018) Katerina Koussoulas et al. Frontiers in Physiology
- Polyamines: Bio-Molecules with Diverse Functions in Plant and Human Health and Disease
- (2018) Avtar K. Handa et al. Frontiers in Chemistry
- A Neural Circuit for Gut-Induced Reward
- (2018) Wenfei Han et al. CELL
- The IDO Inhibitor Coptisine Ameliorates Cognitive Impairment in a Mouse Model of Alzheimer's Disease
- (2018) Dan Yu et al. JOURNAL OF ALZHEIMERS DISEASE
- Cultivable butyrate-producing bacteria of elderly Japanese diagnosed with Alzheimer’s disease
- (2018) Thi Thuy Tien Nguyen et al. JOURNAL OF MICROBIOLOGY
- Microbial tryptophan catabolites in health and disease
- (2018) Henrik M. Roager et al. Nature Communications
- Healthy Aging and Dementia: Two Roads Diverging in Midlife?
- (2018) Katie Irwin et al. Frontiers in Aging Neuroscience
- Gut microbiota, cognitive frailty and dementia in older individuals: a systematic review
- (2018) Andrea Ticinesi et al. Clinical Interventions in Aging
- Bile Acid Synthesis: From Nature to the Chemical Modification and Synthesis and Their Applications as Drugs and Nutrients
- (2018) Tanja M. Šarenac et al. Frontiers in Pharmacology
- Altered bile acid profile in mild cognitive impairment and Alzheimer's disease: Relationship to neuroimaging and CSF biomarkers
- (2018) Kwangsik Nho et al. Alzheimers & Dementia
- Altered bile acid profile associates with cognitive impairment in Alzheimer's disease—An emerging role for gut microbiome
- (2018) Siamak MahmoudianDehkordi et al. Alzheimers & Dementia
- Spermidine: a physiological autophagy inducer acting as an anti-aging vitamin in humans?
- (2018) Frank Madeo et al. Autophagy
- The kynurenine pathway and cognitive performance in community-dwelling older adults. The Hordaland Health Study
- (2018) Stein-Erik Hafstad Solvang et al. BRAIN BEHAVIOR AND IMMUNITY
- Microbially Produced Imidazole Propionate Impairs Insulin Signaling through mTORC1
- (2018) Ara Koh et al. CELL
- Dopamine: Functions, Signaling, and Association with Neurological Diseases
- (2018) Marianne O. Klein et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- The effect of spermidine on memory performance in older adults at risk for dementia: A randomized controlled trial
- (2018) Miranka Wirth et al. CORTEX
- Activation of Nrf2/ARE pathway alleviates the cognitive deficits in PS1V97L-Tg mouse model of Alzheimer’s disease through modulation of oxidative stress
- (2018) Yuanruhua Tian et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Vitamin K status and inflammation are associated with cognition in older Irish adults
- (2018) A. Kiely et al. NUTRITIONAL NEUROSCIENCE
- Low Serum Tryptophan Levels as an Indicator of Global Cognitive Performance in Nondemented Women over 50 Years of Age
- (2018) L. A. Ramos-Chávez et al. Oxidative Medicine and Cellular Longevity
- Implication of Trimethylamine N-Oxide (TMAO) in Disease: Potential Biomarker or New Therapeutic Target
- (2018) Manuel Janeiro et al. Nutrients
- Trimethylamine-N-oxide (TMAO) as Novel Potential Biomarker of Early Predictors of Metabolic Syndrome
- (2018) Luigi Barrea et al. Nutrients
- The gut microbiota-derived metabolite trimethylamine N-oxide is elevated in Alzheimer’s disease
- (2018) Nicholas M. Vogt et al. Alzheimers Research & Therapy
- GABA-modulating bacteria of the human gut microbiota
- (2018) Philip Strandwitz et al. Nature Microbiology
- Gut microbiota functions: metabolism of nutrients and other food components
- (2017) Ian Rowland et al. EUROPEAN JOURNAL OF NUTRITION
- Protective roles of intestinal microbiota derived short chain fatty acids in Alzheimer’s disease-type beta-amyloid neuropathological mechanisms
- (2017) Lap Ho et al. Expert Review of Neurotherapeutics
- Probiotic Bifidobacterium longum NCC3001 Reduces Depression Scores and Alters Brain Activity: A Pilot Study in Patients With Irritable Bowel Syndrome
- (2017) Maria Ines Pinto-Sanchez et al. GASTROENTEROLOGY
- TUDCA: An Agonist of the Bile Acid Receptor GPBAR1/TGR5 With Anti-Inflammatory Effects in Microglial Cells
- (2017) Natalia Yanguas-Casás et al. JOURNAL OF CELLULAR PHYSIOLOGY
- The vicious circle of hypometabolism in neurodegenerative diseases: Ways and mechanisms of metabolic correction
- (2017) Yuri Zilberter et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Mass spectrometry-based metabolomics: Targeting the crosstalk between gut microbiota and brain in neurodegenerative disorders
- (2017) Hemi Luan et al. MASS SPECTROMETRY REVIEWS
- Bile acid quantification of 20 plasma metabolites identifies lithocholic acid as a putative biomarker in Alzheimer’s disease
- (2017) Josef Marksteiner et al. Metabolomics
- Association of brain amyloidosis with pro-inflammatory gut bacterial taxa and peripheral inflammation markers in cognitively impaired elderly
- (2017) Annamaria Cattaneo et al. NEUROBIOLOGY OF AGING
- L-Tryptophan-kynurenine pathway enzymes are therapeutic target for neuropsychiatric diseases: Focus on cell type differences
- (2017) Hidetsugu Fujigaki et al. NEUROPHARMACOLOGY
- Recent evidence for an expanded role of the kynurenine pathway of tryptophan metabolism in neurological diseases
- (2017) Michael D. Lovelace et al. NEUROPHARMACOLOGY
- The relationship between obesity and cognitive health and decline
- (2017) Louise Dye et al. PROCEEDINGS OF THE NUTRITION SOCIETY
- Lactobacillus reuteriinduces gut intraepithelial CD4+CD8αα+T cells
- (2017) Luisa Cervantes-Barragan et al. SCIENCE
- Unconjugated bile acids in rat brain: Analytical method based on LC/ESI-MS/MS with chemical derivatization and estimation of their origin by comparison to serum levels
- (2017) Tatsuya Higashi et al. STEROIDS
- The Gut Microbial Metabolite Trimethylamine-N-Oxide Is Present in Human Cerebrospinal Fluid
- (2017) Daniele Del Rio et al. Nutrients
- The Neuroprotective Effects of Phenolic Acids: Molecular Mechanism of Action
- (2017) et al. Nutrients
- Protein-bound uremic toxins impaired mitochondrial dynamics and functions
- (2017) Chiao-Yin Sun et al. Oncotarget
- Protective roles of intestinal microbiota derived short chain fatty acids in Alzheimer’s disease-type beta-amyloid neuropathological mechanisms
- (2017) Lap Ho et al. Expert Review of Neurotherapeutics
- Trimethylamine‐N‐Oxide Induces Vascular Inflammation by Activating the NLRP3 Inflammasome Through the SIRT3‐SOD2‐mtROS Signaling Pathway
- (2017) Ming‐liang Chen et al. Journal of the American Heart Association
- Bile Acid Signaling Pathways from the Enterohepatic Circulation to the Central Nervous System
- (2017) Kim L. Mertens et al. Frontiers in Neuroscience
- Blood Trimethylamine-N-Oxide Originates from Microbiota Mediated Breakdown of Phosphatidylcholine and Absorption from Small Intestine
- (2017) Wolfgang Stremmel et al. PLoS One
- Hepatic alterations are accompanied by changes to bile acid transporter-expressing neurons in the hypothalamus after traumatic brain injury
- (2017) Damir Nizamutdinov et al. Scientific Reports
- Functional Coupling of Human Microphysiology Systems: Intestine, Liver, Kidney Proximal Tubule, Blood-Brain Barrier and Skeletal Muscle
- (2017) Lawrence Vernetti et al. Scientific Reports
- Gut microbiome alterations in Alzheimer’s disease
- (2017) Nicholas M. Vogt et al. Scientific Reports
- Blood metabolite markers of preclinical Alzheimer's disease in two longitudinally followed cohorts of older individuals
- (2016) Ramon Casanova et al. Alzheimers & Dementia
- Age-related changes in gut microbiota composition from newborn to centenarian: a cross-sectional study
- (2016) Toshitaka Odamaki et al. BMC MICROBIOLOGY
- Towards understanding brain-gut-microbiome connections in Alzheimer’s disease
- (2016) Rong Xu et al. BMC Systems Biology
- Cognitive impairment by antibiotic-induced gut dysbiosis: Analysis of gut microbiota-brain communication
- (2016) Esther E. Fröhlich et al. BRAIN BEHAVIOR AND IMMUNITY
- Sodium butyrate exerts neuroprotective effects by restoring the blood-brain barrier in traumatic brain injury mice
- (2016) Haixiao Li et al. BRAIN RESEARCH
- Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk
- (2016) Weifei Zhu et al. CELL
- Alzheimer's disease: Targeting the Cholinergic System
- (2016) Talita H. Ferreira-Vieira et al. Current Neuropharmacology
- Effects of bile acids on neurological function and disease
- (2016) Matthew McMillin et al. FASEB JOURNAL
- Chitosan oligosaccharides alleviate cognitive deficits in an amyloid-β1–42-induced rat model of Alzheimer's disease
- (2016) Shiliang Jia et al. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
- Growing up in a Bubble: Using Germ-Free Animals to Assess the Influence of the Gut Microbiota on Brain and Behavior
- (2016) Pauline Luczynski et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- Increased dietary vitamin K intake is associated with less severe subjective memory complaint among older adults
- (2016) Anne Soutif-Veillon et al. MATURITAS
- HDAC Inhibitor Sodium Butyrate-Mediated Epigenetic Regulation Enhances Neuroprotective Function of Microglia During Ischemic Stroke
- (2016) Radhika Patnala et al. MOLECULAR NEUROBIOLOGY
- Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor
- (2016) Veit Rothhammer et al. NATURE MEDICINE
- The neuropharmacology of butyrate: The bread and butter of the microbiota-gut-brain axis?
- (2016) Roman M. Stilling et al. NEUROCHEMISTRY INTERNATIONAL
- Effects of scFOS on the composition of fecal microbiota and anxiety in patients with irritable bowel syndrome: a randomized, double blind, placebo controlled study
- (2016) F. Azpiroz et al. NEUROGASTROENTEROLOGY AND MOTILITY
- Modulation of learning and memory by natural polyamines
- (2016) Gustavo Petri Guerra et al. PHARMACOLOGICAL RESEARCH
- p-Cresyl sulfate affects the oxidative burst, phagocytosis process, and antigen presentation of monocyte-derived macrophages
- (2016) M.L.V. Azevedo et al. TOXICOLOGY LETTERS
- Influence of Tryptophan and Serotonin on Mood and Cognition with a Possible Role of the Gut-Brain Axis
- (2016) Trisha Jenkins et al. Nutrients
- Trimethylamine N-Oxide: The Good, the Bad and the Unknown
- (2016) Manuel Velasquez et al. Toxins
- Trimethylamine N‐Oxide Promotes Vascular Inflammation Through Signaling of Mitogen‐Activated Protein Kinase and Nuclear Factor‐κB
- (2016) Marcus M. Seldin et al. Journal of the American Heart Association
- Serum Trimethylamine-N-Oxide Is Strongly Related to Renal Function and Predicts Outcome in Chronic Kidney Disease
- (2016) Catharina Missailidis et al. PLoS One
- Impact of diabetes on cognitive function and brain structure
- (2015) Amir Moheet et al. Annals of the New York Academy of Sciences
- Gut microbiota depletion from early adolescence in mice: Implications for brain and behaviour
- (2015) Lieve Desbonnet et al. BRAIN BEHAVIOR AND IMMUNITY
- The roles of peripheral serotonin in metabolic homeostasis
- (2015) Rabih El-Merahbi et al. FEBS LETTERS
- Gut permeability, its interaction with gut microflora and effects on metabolic health are mediated by the lymphatics system, liver and bile acid
- (2015) Cuong D Tran et al. Future Microbiology
- Modulation of Gut Microbiota–Brain Axis by Probiotics, Prebiotics, and Diet
- (2015) Xiaofei Liu et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Role of intestinal microbiota in the generation of polyphenol-derived phenolic acid mediated attenuation of Alzheimer's disease β-amyloid oligomerization
- (2015) Dongjie Wang et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Gut biogeography of the bacterial microbiota
- (2015) Gregory P. Donaldson et al. NATURE REVIEWS MICROBIOLOGY
- Amyloid-β pathology is attenuated by tauroursodeoxycholic acid treatment in APP/PS1 mice after disease onset
- (2015) Pedro A. Dionísio et al. NEUROBIOLOGY OF AGING
- TMAO: A small molecule of great expectations
- (2015) Marcin Ufnal et al. NUTRITION
- Gut microbiota and aging
- (2015) P. W. OToole et al. SCIENCE
- What has serotonin to do with depression?
- (2015) Philip J. Cowen et al. World Psychiatry
- Mild cognitive impairment and its management in older people
- (2015) Sima Ataollahi Eshkoor et al. Clinical Interventions in Aging
- Plasma 24-metabolite Panel Predicts Preclinical Transition to Clinical Stages of Alzheimer’s Disease
- (2015) Massimo S. Fiandaca et al. Frontiers in Neurology
- Antidepressant-Like Effect of Sodium Butyrate is Associated with an Increase in TET1 and in 5-Hydroxymethylation Levels in the Bdnf Gene
- (2015) Y. B. Wei et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- Adaptation of the human aryl hydrocarbon receptor to sense microbiota-derived indoles
- (2015) Troy D. Hubbard et al. Scientific Reports
- Measurement of trimethylamine-N-oxide by stable isotope dilution liquid chromatography tandem mass spectrometry
- (2014) Zeneng Wang et al. ANALYTICAL BIOCHEMISTRY
- Role of Monocarboxylate Transporters in Drug Delivery to the Brain
- (2014) Nisha Vijay et al. CURRENT PHARMACEUTICAL DESIGN
- Bile acids permeabilize the blood brain barrier after bile duct ligation in rats via Rac1-dependent mechanisms
- (2014) Matthew Quinn et al. DIGESTIVE AND LIVER DISEASE
- Arsenic Exposure Perturbs the Gut Microbiome and Its Metabolic Profile in Mice: An Integrated Metagenomics and Metabolomics Analysis
- (2014) Kun Lu et al. ENVIRONMENTAL HEALTH PERSPECTIVES
- Dietary trimethylamine N-oxide exacerbates impaired glucose tolerance in mice fed a high fat diet
- (2014) Xiang Gao et al. JOURNAL OF BIOSCIENCE AND BIOENGINEERING
- Gut Microbes and the Brain: Paradigm Shift in Neuroscience
- (2014) E. A. Mayer et al. JOURNAL OF NEUROSCIENCE
- Prognostic Value of Elevated Levels of Intestinal Microbe-Generated Metabolite Trimethylamine-N-Oxide in Patients With Heart Failure
- (2014) W.H. Wilson Tang et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- The gut microbiota influences blood-brain barrier permeability in mice
- (2014) V. Braniste et al. Science Translational Medicine
- Upregulation of colonic luminal polyamines produced by intestinal microbiota delays senescence in mice
- (2014) Ryoko Kibe et al. Scientific Reports
- White matter microstructure in late middle-age: Effects of apolipoprotein E4 and parental family history of Alzheimer's disease
- (2014) Nagesh Adluru et al. NeuroImage-Clinical
- The kynurenine pathway as a therapeutic target in cognitive and neurodegenerative disorders
- (2013) Trevor W Stone et al. BRITISH JOURNAL OF PHARMACOLOGY
- Serotonin – Kynurenine Hypothesis of Depression: Historical Overview and Recent Developments
- (2013) Gregory Oxenkrug CURRENT DRUG TARGETS
- Tryptophan Catabolites from Microbiota Engage Aryl Hydrocarbon Receptor and Balance Mucosal Reactivity via Interleukin-22
- (2013) Teresa Zelante et al. IMMUNITY
- Altered profile of human gut microbiome is associated with cirrhosis and its complications
- (2013) Jasmohan S. Bajaj et al. JOURNAL OF HEPATOLOGY
- The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism
- (2013) Gijs den Besten et al. JOURNAL OF LIPID RESEARCH
- The role of serotonin in cognitive function: evidence from recent studies and implications for understanding depression
- (2013) Philip Cowen et al. JOURNAL OF PSYCHOPHARMACOLOGY
- Major phenylpropanoid-derived metabolites in the human gut can arise from microbial fermentation of protein
- (2013) Wendy R. Russell et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Richness of human gut microbiome correlates with metabolic markers
- (2013) Emmanuelle Le Chatelier et al. NATURE
- Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis
- (2013) Robert A Koeth et al. NATURE MEDICINE
- The immune marker CD68 correlates with cognitive impairment in normally aged rats
- (2013) Mark Farso et al. NEUROBIOLOGY OF AGING
- Quinolinic Acid: An Endogenous Neurotoxin with Multiple Targets
- (2013) Rafael Lugo-Huitrón et al. Oxidative Medicine and Cellular Longevity
- Commensal Bacteria-Dependent Indole Production Enhances Epithelial Barrier Function in the Colon
- (2013) Yosuke Shimada et al. PLoS One
- Dopamine Signaling in reward-related behaviors
- (2013) Ja-Hyun Baik Frontiers in Neural Circuits
- Metabolic profiling of Alzheimer's disease brains
- (2013) Koichi Inoue et al. Scientific Reports
- Alterations in metabolic pathways and networks in Alzheimer’s disease
- (2013) R Kaddurah-Daouk et al. Translational Psychiatry
- Toward a unified biological hypothesis for the BDNF Val66Met-associated memory deficits in humans: a model of impaired dendritic mRNA trafficking
- (2013) Gabriele Baj et al. Frontiers in Neuroscience
- Colonic mucosal microbiome differs from stool microbiome in cirrhosis and hepatic encephalopathy and is linked to cognition and inflammation
- (2012) Jasmohan S. Bajaj et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Critical role of gut microbiota in the production of biologically active, free catecholamines in the gut lumen of mice
- (2012) Yasunari Asano et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- The association between cognitive function and white matter lesion location in older adults: a systematic review
- (2012) Niousha Bolandzadeh et al. BMC Neurology
- Tryptophan depletion in depressed patients occurs independent of kynurenine pathway activation
- (2012) Martina M. Hughes et al. BRAIN BEHAVIOR AND IMMUNITY
- Modulation of Inflammatory Cytokines and Mitogen-activated Protein Kinases by Acetate in Primary Astrocytes
- (2012) Mahmoud L. Soliman et al. Journal of Neuroimmune Pharmacology
- Acetate supplementation modulates brain histone acetylation and decreases interleukin-1β expression in a rat model of neuroinflammation
- (2012) Mahmoud L Soliman et al. Journal of Neuroinflammation
- TUDCA, a Bile Acid, Attenuates Amyloid Precursor Protein Processing and Amyloid-β Deposition in APP/PS1 Mice
- (2012) Ana F. Nunes et al. MOLECULAR NEUROBIOLOGY
- The microbiome-gut-brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner
- (2012) G Clarke et al. MOLECULAR PSYCHIATRY
- Brain endogenous liver X receptor ligands selectively promote midbrain neurogenesis
- (2012) Spyridon Theofilopoulos et al. Nature Chemical Biology
- Kynurenines in the mammalian brain: when physiology meets pathology
- (2012) Robert Schwarcz et al. NATURE REVIEWS NEUROSCIENCE
- Gray matter network associated with risk for Alzheimer's disease in young to middle-aged adults
- (2012) Gene E. Alexander et al. NEUROBIOLOGY OF AGING
- Microbial conversion of choline to trimethylamine requires a glycyl radical enzyme
- (2012) S. Craciun et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Host-Gut Microbiota Metabolic Interactions
- (2012) J. K. Nicholson et al. SCIENCE
- Impact of Intestinal Microbiota on Intestinal Luminal Metabolome
- (2012) Mitsuharu Matsumoto et al. Scientific Reports
- Linkage of gut microbiome with cognition in hepatic encephalopathy
- (2011) Jasmohan S. Bajaj et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Deoxycholic and chenodeoxycholic bile acids induce apoptosis via oxidative stress in human colon adenocarcinoma cells
- (2011) Juan Ignacio Barrasa et al. APOPTOSIS
- Role of pro-inflammatory cytokines released from microglia in neurodegenerative diseases
- (2011) Joshua A. Smith et al. BRAIN RESEARCH BULLETIN
- Kynurenine 3-Monooxygenase Inhibition in Blood Ameliorates Neurodegeneration
- (2011) Daniel Zwilling et al. CELL
- Nontraditional Risk Factors and Biomarkers for Cardiovascular Disease: Mechanistic, Research, and Clinical Considerations for Youth
- (2011) Prabhakaran (Babu) Balagopal et al. CIRCULATION
- The Intestinal Microbiota Affect Central Levels of Brain-Derived Neurotropic Factor and Behavior in Mice
- (2011) Premysl Bercik et al. GASTROENTEROLOGY
- Mechanism of acute tryptophan depletion: is it only serotonin?
- (2011) E L van Donkelaar et al. MOLECULAR PSYCHIATRY
- Converging evidence for central 5-HT effects in acute tryptophan depletion
- (2011) M J Crockett et al. MOLECULAR PSYCHIATRY
- The anxiolytic effect of Bifidobacterium longum NCC3001 involves vagal pathways for gut-brain communication
- (2011) P. Bercik et al. NEUROGASTROENTEROLOGY AND MOTILITY
- Age-related changes in the default mode network are more advanced in Alzheimer disease
- (2011) D. T. Jones et al. NEUROLOGY
- Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve
- (2011) J. A. Bravo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Normal gut microbiota modulates brain development and behavior
- (2011) R. D. Heijtz et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cognitive dysfunction with aging and the role of inflammation
- (2011) Arthur A. Simen et al. Therapeutic Advances in Chronic Disease
- Kynurenine and its metabolites in Alzheimer's disease patients
- (2010) E Gulaj et al. Advances in Medical Sciences
- The APOE ɛ4 allele modulates brain white matter integrity in healthy adults
- (2010) V Heise et al. MOLECULAR PSYCHIATRY
- Reduced anxiety-like behavior and central neurochemical change in germ-free mice
- (2010) K. M. Neufeld et al. NEUROGASTROENTEROLOGY AND MOTILITY
- Neuroinflammation and Cognitive Aging
- (2010) Raymond L. Ownby Current Psychiatry Reports
- A Gut Feeling about GABA: Focus on GABAB Receptors
- (2010) Niall P. Hyland et al. Frontiers in Pharmacology
- Small-intestinal bacterial overgrowth in cirrhosis is related to the severity of liver disease
- (2009) C. PANDE et al. ALIMENTARY PHARMACOLOGY & THERAPEUTICS
- Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology
- (2009) Paula I. Moreira et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Meta-Analysis of Alzheimer's Disease Risk with Obesity, Diabetes, and Related Disorders
- (2009) Louis A. Profenno et al. BIOLOGICAL PSYCHIATRY
- Age-associated cognitive decline
- (2009) I. J. Deary et al. BRITISH MEDICAL BULLETIN
- Proinflammatory cytokine interferon-γ increases induction of indoleamine 2,3-dioxygenase in monocytic cells primed with amyloid β peptide 1-42: implications for the pathogenesis of Alzheimer’s disease
- (2009) Akiko Yamada et al. JOURNAL OF NEUROCHEMISTRY
- Effect of quinolinic acid on human astrocytes morphology and functions: implications in Alzheimer's disease
- (2009) Ka Ting et al. Journal of Neuroinflammation
- Structure and function of the blood–brain barrier
- (2009) N. Joan Abbott et al. NEUROBIOLOGY OF DISEASE
- The Excitotoxin Quinolinic Acid Induces Tau Phosphorylation in Human Neurons
- (2009) Abdur Rahman et al. PLoS One
- Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites
- (2009) W. R. Wikoff et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The bacterial signal indole increases epithelial-cell tight-junction resistance and attenuates indicators of inflammation
- (2009) T. Bansal et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Bile acids as endogenous etiologic agents in gastrointestinal cancer
- (2009) Harris Bernstein et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Effects of Hypertension and Hypercholesterolemia on Cognitive Functioning in Patients With Alzheimer Disease
- (2008) Felicia C. Goldstein et al. ALZHEIMER DISEASE & ASSOCIATED DISORDERS
- The role of luminal factors in the recovery of gastric function and behavioral changes after chronic Helicobacter pylori infection
- (2008) Elena F. Verdu et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Subcellular localization of transporters along the rat blood–brain barrier and blood–cerebral-spinal fluid barrier by in vivo biotinylation
- (2008) L.M. Roberts et al. NEUROSCIENCE
- Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41
- (2008) B. S. Samuel et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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