Gut permeability, its interaction with gut microflora and effects on metabolic health are mediated by the lymphatics system, liver and bile acid

Mucosal-associated invariant T cell alterations in obese and type 2 diabetic patients

(2015) Isabelle Magalhaes et al.   JOURNAL OF CLINICAL INVESTIGATION

Dysbiosis gut microbiota associated with inflammation and impaired mucosal immune function in intestine of humans with non-alcoholic fatty liver disease

(2015) Weiwei Jiang et al.   Scientific Reports

Rapidly expanding knowledge on the role of the gut microbiome in health and disease

(2014) M.C. Cénit et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Immune Response and Intestinal Permeability in Children With Acute Gastroenteritis Treated With Lactobacillus rhamnosus GG: A Randomized, Double-Blind, Placebo-Controlled Trial

(2014) Kulandaipalayam N. C. Sindhu et al.   CLINICAL INFECTIOUS DISEASES

Host-Microbiome Interactions in Alcoholic Liver Disease

(2014) Peng Chen et al.   Gut and Liver

Human Lymphatic Endothelial Cells Express Multiple Functional TLRs

(2014) A. Pegu et al.   JOURNAL OF IMMUNOLOGY

Gut microbiota in children with type 1 diabetes differs from that in healthy children: a case-control study

(2013) Mora Murri et al.   BMC Medicine

The Origins and Drivers of Insulin Resistance

(2013) Andrew M.F. Johnson et al.   CELL

Apelin Inhibits Diet-Induced Obesity by Enhancing Lymphatic and Blood Vessel Integrity

(2013) M. Sawane et al.   DIABETES

TGR5 signalling inhibits the production of pro-inflammatory cytokines byin vitrodifferentiated inflammatory and intestinal macrophages in Crohn's disease

(2013) Kazuaki Yoneno et al.   IMMUNOLOGY

Rotavirus Infection Increases Intestinal Motility but Not Permeability at the Onset of Diarrhea

(2013) C. Istrate et al.   JOURNAL OF VIROLOGY

What is the role of adiponectin in obesity related non-alcoholic fatty liver disease?

(2013) Carmine Finelli   WORLD JOURNAL OF GASTROENTEROLOGY

Acute effects of rotavirus and malnutrition on intestinal barrier function in neonatal piglets

(2013) Sheila K Jacobi   WORLD JOURNAL OF GASTROENTEROLOGY

A novel cobiotic containing a prebiotic and an antioxidant augments the glucose control and gastrointestinal tolerability of metformin: a case report

(2013) F. Greenway et al.   Beneficial Microbes

An Adult Mouse Model of Vibrio cholerae-induced Diarrhea for Studying Pathogenesis and Potential Therapy of Cholera

(2013) Sutthipong Sawasvirojwong et al.   PLoS Neglected Tropical Diseases

Regulation of intestinal epithelial permeability by tight junctions

(2012) Takuya Suzuki   CELLULAR AND MOLECULAR LIFE SCIENCES

Connecting dysbiosis, bile-acid dysmetabolism and gut inflammation in inflammatory bowel diseases

(2012) Henri Duboc et al.   GUT

Adipokines from local fat cells shape the macrophage compartment of the creeping fat in Crohn's disease

(2012) Lea Isabell Kredel et al.   GUT

The Staphylococcus aureus Alpha-Toxin Perturbs the Barrier Function in Caco-2 Epithelial Cell Monolayers by Altering Junctional Integrity

(2012) Young-Keun Kwak et al.   INFECTION AND IMMUNITY

Reduced adipose tissue lymphatic drainage of macromolecules in obese subjects: a possible link between obesity and local tissue inflammation?

(2012) N Arngrim et al.   INTERNATIONAL JOURNAL OF OBESITY

Functional interactions between the gut microbiota and host metabolism

(2012) Valentina Tremaroli et al.   NATURE

Increase in fecal primary bile acids and dysbiosis in patients with diarrhea-predominant irritable bowel syndrome

(2012) H. Duboc et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Gut–liver axis: The impact of gut microbiota on non alcoholic fatty liver disease

(2012) D. Compare et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Potential mechanisms for the emerging link between obesity and increased intestinal permeability

(2012) Tatiana F.S. Teixeira et al.   NUTRITION RESEARCH

Lipopolysaccharides Impair Insulin Gene Expression in Isolated Islets of Langerhans via Toll-Like Receptor-4 and NF-κB Signalling

(2012) Julie Amyot et al.   PLoS One

Host-Gut Microbiota Metabolic Interactions

(2012) J. K. Nicholson et al.   SCIENCE

High-fat-induced intestinal permeability dysfunction associated with altered fecal bile acids

(2012) Lotta K Stenman   WORLD JOURNAL OF GASTROENTEROLOGY

Toll-like receptor deficiency worsens inflammation and lymphedema after lymphatic injury

(2011) Jamie C. Zampell et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Impairments in the intrinsic contractility of mesenteric collecting lymphatics in a rat model of metabolic syndrome

(2011) Scott D. Zawieja et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

'Gut health': a new objective in medicine?

(2011) Stephan C Bischoff   BMC Medicine

Role of the lymphatic system in the pathogenesis of Crohnʼs disease

(2011) Pierre-Yves von der Weid et al.   CURRENT OPINION IN GASTROENTEROLOGY

Responses of Gut Microbiota and Glucose and Lipid Metabolism to Prebiotics in Genetic Obese and Diet-Induced Leptin-Resistant Mice

(2011) Amandine Everard et al.   DIABETES

Intestinal mucosal adherence and translocation of commensal bacteria at the early onset of type 2 diabetes: molecular mechanisms and probiotic treatment

(2011) Jacques Amar et al.   EMBO Molecular Medicine

Bacterial infections in cirrhosis: role of proton pump inhibitors and intestinal permeability

(2011) Lotte G. van Vlerken et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Intestinal permeability in coeliac disease: insight into mechanisms and relevance to pathogenesis

(2011) Martine Heyman et al.   GUT

Characterization of fecal microbial communities in patients with liver cirrhosis

(2011) Yanfei Chen et al.   HEPATOLOGY

Relationship between nonalcoholic fatty liver disease and metabolic syndrome

(2011) Shao Hua CHEN et al.   Journal of Digestive Diseases

Gut microbiota, epithelial function and derangements in obesity

(2011) Helen E. Raybould   JOURNAL OF PHYSIOLOGY-LONDON

Mesenteric Lymph Flow in Endotoxemic Guinea Pigs

(2011) Kayo Nemoto et al.   Lymphatic Research and Biology

Liver Enzymes, Type 2 Diabetes, and Metabolic Syndrome in Middle-Aged, Urban Chinese Men

(2011) Raquel Villegas et al.   Metabolic Syndrome and Related Disorders

Enterotypes of the human gut microbiome

(2011) Manimozhiyan Arumugam et al.   NATURE

Role of the Gut in Visceral Fat Inflammation and Metabolic Disorders

(2011) Yan Y. Lam et al.   Obesity

Intestinal Permeability Is Associated With Visceral Adiposity in Healthy Women

(2011) Anders Gummesson et al.   Obesity

Responses of Gut Microbiota to Diet Composition and Weight Loss in Lean and Obese Mice

(2011) Yann Ravussin et al.   Obesity

Zonulin and Its Regulation of Intestinal Barrier Function: The Biological Door to Inflammation, Autoimmunity, and Cancer

(2011) Alessio Fasano   PHYSIOLOGICAL REVIEWS

The Bile Acid Receptor GPBAR-1 (TGR5) Modulates Integrity of Intestinal Barrier and Immune Response to Experimental Colitis

(2011) Sabrina Cipriani et al.   PLoS One

Intestinal Microbiota and Innate Immunity-Related Gene Alteration in Cirrhotic Rats with Liver Transplantation

(2011) Y.R. Xie et al.   TRANSPLANTATION PROCEEDINGS

Metabolic Regulation of Mycobacterial Growth and Antibiotic Sensitivity

(2011) Seung-Hun Baek et al.   PLOS BIOLOGY

Pilot study: alterations of intestinal microbiota in obese humans are not associated with colonic inflammation or disturbances of barrier function

(2010) J. Brignardello et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Review article: lymphatic system and associated adipose tissue in the development of inflammatory bowel disease

(2010) P.-Y. Von Der Weid et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Epidemiology of Non-Alcoholic Fatty Liver Disease

(2010) Stefano Bellentani et al.   DIGESTIVE DISEASES

A human gut microbial gene catalogue established by metagenomic sequencing

(2010) Junjie Qin et al.   NATURE

Dietary fat and bile juice, but not obesity, are responsible for the increase in small intestinal permeability induced through the suppression of tight junction protein expression in LETO and OLETF rats

(2010) Takuya Suzuki et al.   Nutrition & Metabolism

Do nutrient-gut-microbiota interactions play a role in human obesity, insulin resistance and type 2 diabetes?

(2010) M. Diamant et al.   Obesity Reviews

Gut Microbiota in Human Adults with Type 2 Diabetes Differs from Non-Diabetic Adults

(2010) Nadja Larsen et al.   PLoS One

Systemic gut microbial modulation of bile acid metabolism in host tissue compartments

(2010) J. R. Swann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Small-intestinal bacterial overgrowth in cirrhosis is related to the severity of liver disease

(2009) C. PANDE et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Listeriolysin O affects barrier function and induces chloride secretion in HT-29/B6 colon epithelial cells

(2009) Jan F. Richter et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Obesity and the human microbiome

(2009) Ruth E Ley   CURRENT OPINION IN GASTROENTEROLOGY

Gut barrier disruption by an enteric bacterial pathogen accelerates insulitis in NOD mice

(2009) A. S. Lee et al.   DIABETOLOGIA

Could inflammatory markers help diagnose nonalcoholic steatohepatitis?

(2009) Giovanni Tarantino et al.   EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability

(2009) P. D. Cani et al.   GUT

Increased intestinal permeability and tight junction alterations in nonalcoholic fatty liver disease

(2009) Luca Miele et al.   HEPATOLOGY

New insights into alcoholic pancreatitis and pancreatic cancer

(2009) Minoti Apte et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Arcobacter butzleriInduces Barrier Dysfunction in Intestinal HT‐29/B6 Cells

(2009) Roland Bücker et al.   JOURNAL OF INFECTIOUS DISEASES

Subcutaneous and visceral adipose tissue: structural and functional differences

(2009) M. Mohsen Ibrahim   Obesity Reviews

Role of Bile Acids and Bile Acid Receptors in Metabolic Regulation

(2009) Philippe Lefebvre et al.   PHYSIOLOGICAL REVIEWS

SYSTEMIC INFLAMMATION INCREASES INTESTINAL PERMEABILITY DURING EXPERIMENTAL HUMAN ENDOTOXEMIA

(2009) Falco Hietbrink et al.   SHOCK

Bile-acid-activated receptors: targeting TGR5 and farnesoid-X-receptor in lipid and glucose disorders

(2009) Stefano Fiorucci et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Physiology and Function of the Tight Junction

(2009) J. M. Anderson et al.   Cold Spring Harbor Perspectives in Biology

The Link between Lymphatic Function and Adipose Biology

(2008) Natasha L. Harvey   Annals of the New York Academy of Sciences

Changes in Gut Microbiota Control Metabolic Endotoxemia-Induced Inflammation in High-Fat Diet-Induced Obesity and Diabetes in Mice

(2008) P. D. Cani et al.   DIABETES

Innate immunity and intestinal microbiota in the development of Type 1 diabetes

(2008) Li Wen et al.   NATURE

Targeting bile-acid signalling for metabolic diseases

(2008) Charles Thomas et al.   NATURE REVIEWS DRUG DISCOVERY

Endotoxaemia leads to major increases in inflammatory adipokine gene expression in white adipose tissue of mice

(2008) Martin Leuwer et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY