Gut Metabolite TMAO Induces Synaptic Plasticity Deficits by Promoting Endoplasmic Reticulum Stress

The Links Between the Gut Microbiome, Aging, Modern Lifestyle and Alzheimer's Disease

(2020) Sholpan Askarova et al.   Frontiers in Cellular and Infection Microbiology

Gut microbe-generated metabolite trimethylamine N -oxide and the risk of diabetes: A systematic review and dose-response meta-analysis

(2019) Rulin Zhuang et al.   Obesity Reviews

Assessment of Causal Direction Between Gut Microbiota-Dependent Metabolites and Cardiometabolic Health: Abi-Directional Mendelian Randomisation Analysis

(2019) Jinzhu Jia et al.   DIABETES

Trimethylamine N-Oxide Binds and Activates PERK to Promote Metabolic Dysfunction

(2019) Sifan Chen et al.   Cell Metabolism

Neuroinflammation and the Gut Microbiota: Possible Alternative Therapeutic Targets to Counteract Alzheimer’s Disease?

(2019) Milica Cerovic et al.   Frontiers in Aging Neuroscience

Adiponectin Knockout Mice Display Cognitive and Synaptic Deficits

(2019) Jenna Bloemer et al.   Frontiers in Endocrinology

The microbiota-immune axis as a central mediator of gut-brain communication

(2019) Thomas C. Fung   NEUROBIOLOGY OF DISEASE

Trimethylamine-N -oxide promotes brain aging and cognitive impairment in mice

(2018) Dang Li et al.   AGING CELL

The gut microbiota-derived metabolite trimethylamine N-oxide is elevated in Alzheimer’s disease

(2018) Nicholas M. Vogt et al.   Alzheimers Research & Therapy

The Gut Microbiota and Alzheimer’s Disease

(2017) Chunmei Jiang et al.   JOURNAL OF ALZHEIMERS DISEASE

Local Inhibition of PERK Enhances Memory and Reverses Age-Related Deterioration of Cognitive and Neuronal Properties

(2017) Vijendra Sharma et al.   JOURNAL OF NEUROSCIENCE

Interactions between the microbiota, immune and nervous systems in health and disease

(2017) Thomas C Fung et al.   NATURE NEUROSCIENCE

Association of brain amyloidosis with pro-inflammatory gut bacterial taxa and peripheral inflammation markers in cognitively impaired elderly

(2017) Annamaria Cattaneo et al.   NEUROBIOLOGY OF AGING

The AMPA Receptor Subunit GluA1 is Required for CA1 Hippocampal Long-Term Potentiation but is not Essential for Synaptic Transmission

(2017) Akira Terashima et al.   NEUROCHEMICAL RESEARCH

The TMAO-Producing Enzyme Flavin-Containing Monooxygenase 3 Regulates Obesity and the Beiging of White Adipose Tissue

(2017) Rebecca C. Schugar et al.   Cell Reports

Diabetes is Associated with Higher Trimethylamine N-oxide Plasma Levels

(2016) M. Dambrova et al.   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

The Hybrid Mouse Diversity Panel: a resource for systems genetics analyses of metabolic and cardiovascular traits

(2016) Aldons J. Lusis et al.   JOURNAL OF LIPID RESEARCH

Trimethylamine N‐Oxide Promotes Vascular Inflammation Through Signaling of Mitogen‐Activated Protein Kinase and Nuclear Factor‐κB

(2016) Marcus M. Seldin et al.   Journal of the American Heart Association

Central activation of PPAR-gamma ameliorates diabetes induced cognitive dysfunction and improves BDNF expression

(2015) Thiruchelvam Kariharan et al.   NEUROBIOLOGY OF AGING

Review: Modulating the unfolded protein response to prevent neurodegeneration and enhance memory

(2015) Mark Halliday et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Impaired ILK Function Is Associated with Deficits in Hippocampal Based Memory and Synaptic Plasticity in a FASD Rat Model

(2015) D. Bhattacharya et al.   PLoS One

Dietary trimethylamine N-oxide exacerbates impaired glucose tolerance in mice fed a high fat diet

(2014) Xiang Gao et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

The eIF2  kinase PERK limits the expression of hippocampal metabotropic glutamate receptor-dependent long-term depression

(2014) M. A. Trinh et al.   LEARNING & MEMORY

Memory loss in Alzheimer's disease: are the alterations in the UPR network involved in the cognitive impairment?

(2014) Claudia Duran-Aniotz et al.   Frontiers in Aging Neuroscience

Neuroprotective effects of the amylin analogue pramlintide on Alzheimer's disease pathogenesis and cognition

(2013) Brittany L. Adler et al.   NEUROBIOLOGY OF AGING

NMDA Receptor-Dependent Long-Term Potentiation and Long-Term Depression (LTP/LTD)

(2012) C. Luscher et al.   Cold Spring Harbor Perspectives in Biology

Developmental nicotine exposure induced alterations in behavior and glutamate receptor function in hippocampus

(2011) Kodeeswaran Parameshwaran et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease

(2011) Zeneng Wang et al.   NATURE

Central insulin resistance and synaptic dysfunction in intracerebroventricular-streptozotocin injected rodents

(2011) Brian C. Shonesy et al.   NEUROBIOLOGY OF AGING

eIF2  Phosphorylation-Dependent Translation in CA1 Pyramidal Cells Impairs Hippocampal Memory Consolidation without Affecting General Translation

(2010) Z. Jiang et al.   JOURNAL OF NEUROSCIENCE

Differential induction of bidirectional long-term changes in neurotransmitter release by frequency-coded patterns at the cerebellar input

(2009) Anna D’Errico et al.   JOURNAL OF PHYSIOLOGY-LONDON

Translational Control of Long-Lasting Synaptic Plasticity and Memory

(2009) Mauro Costa-Mattioli et al.   NEURON

Altered protein synthesis is a trigger for long-term memory formation

(2007) Eric Klann et al.   NEUROBIOLOGY OF LEARNING AND MEMORY