Gut microbial molecules in behavioural and neurodegenerative conditions

Establishing or Exaggerating Causality for the Gut Microbiome: Lessons from Human Microbiota-Associated Rodents

(2020) Jens Walter et al.   CELL

A gut bacterial amyloid promotes α-synuclein aggregation and motor impairment in mice

(2020) Timothy R Sampson et al.   eLife

Propionic Acid Shapes the Multiple Sclerosis Disease Course by an Immunomodulatory Mechanism

(2020) Alexander Duscha et al.   CELL

Bile acid metabolism is altered in multiple sclerosis and supplementation ameliorates neuroinflammation

(2020) Pavan Bhargava et al.   JOURNAL OF CLINICAL INVESTIGATION

Gut microbiota from persons with attention-deficit/hyperactivity disorder affects the brain in mice

(2020) Anouk C. Tengeler et al.   Microbiome

Bifidobacterium with the role of 5-hydroxytryptophan synthesis regulation alleviate the symptom of depression and related microbiota dysbiosis

(2019) Peijun Tian et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Therapeutic Effect of Agmatine on Neurological Disease: Focus on Ion Channels and Receptors

(2019) Sumit Barua et al.   NEUROCHEMICAL RESEARCH

Occurrence of the potent mutagens 2- nitrobenzanthrone and 3-nitrobenzanthrone in fine airborne particles

(2019) Aldenor G. Santos et al.   Scientific Reports

The gut microbiome from patients with schizophrenia modulates the glutamate-glutamine-GABA cycle and schizophrenia-relevant behaviors in mice

(2019) Peng Zheng et al.   Science Advances

Selective Estrogen Receptor Modulators Enhance CNS Remyelination Independent of Estrogen Receptors

(2019) Kelsey A. Rankin et al.   JOURNAL OF NEUROSCIENCE

Impact of microbiota on central nervous system and neurological diseases: the gut-brain axis

(2019) Qianquan Ma et al.   Journal of Neuroinflammation

The therapeutic and nutraceutical potential of agmatine, and its enhanced production using Aspergillus oryzae

(2019) Naoki Akasaka et al.   AMINO ACIDS

Review on Bile Acids: Effects of the Gut Microbiome, Interactions with Dietary Fiber, and Alterations in the Bioaccessibility of Bioactive Compounds

(2019) Jashbir Singh et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

TLR2 Plays a Pivotal Role in Mediating Mucosal Serotonin Production in the Gut

(2019) Huaqing Wang et al.   JOURNAL OF IMMUNOLOGY

Gene expression in oligodendrocytes during remyelination reveals cholesterol homeostasis as a therapeutic target in multiple sclerosis

(2019) Rhonda R. Voskuhl et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exposure of Hyperandrogen During Pregnancy Causes Depression- and Anxiety-Like Behaviors, and Reduced Hippocampal Neurogenesis in Rat Offspring

(2019) Juan Cheng et al.   Frontiers in Neuroscience

Fecal metabolite of a gnotobiotic mouse transplanted with gut microbiota from a patient with Alzheimer’s disease

(2019) Yusuke Fujii et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Combination of cannabinoids, delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD), mitigates experimental autoimmune encephalomyelitis (EAE) by altering the gut microbiome

(2019) Zinah Z. Al-Ghezi et al.   BRAIN BEHAVIOR AND IMMUNITY

Human Gut Microbiota from Autism Spectrum Disorder Promote Behavioral Symptoms in Mice

(2019) Gil Sharon et al.   CELL

Influence of maternal microbiota during pregnancy on infant immunity

(2019) Donald D Nyangahu et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Gonadal hormones differentially regulate sex‐specific stress effects on glia in the medial prefrontal cortex

(2019) Justin L. Bollinger et al.   JOURNAL OF NEUROENDOCRINOLOGY

Identification of Altered Metabolic Pathways during Disease Progression in EAE Mice via Metabolomics and Lipidomics

(2019) Gakyung Lee et al.   NEUROSCIENCE

Androgens and depression

(2019) Kevin T. Nead   Current Opinion in Endocrinology Diabetes and Obesity

The role of gut microbiota in shaping the relapse-remitting and chronic-progressive forms of multiple sclerosis in mouse models

(2019) K. Alexa Orr Gandy et al.   Scientific Reports

Neuroinflammation induced by lipopolysaccharide causes cognitive impairment in mice

(2019) Jiayi Zhao et al.   Scientific Reports

Role of Tryptophan in Microbiota-Induced Depressive-Like Behavior: Evidence From Tryptophan Depletion Study

(2019) Iva Lukić et al.   Frontiers in Behavioral Neuroscience

The human gut chemical landscape predicts microbe-mediated biotransformation of foods and drugs

(2019) Leah Guthrie et al.   eLife

Gut Microbiota Interventions With Clostridium butyricum and Norfloxacin Modulate Immune Response in Experimental Autoimmune Encephalomyelitis Mice

(2019) Hao Chen et al.   Frontiers in Immunology

Large-Scale Analyses of Human Microbiomes Reveal Thousands of Small, Novel Genes

(2019) Hila Sberro et al.   CELL

The Landscape of Genetic Content in the Gut and Oral Human Microbiome

(2019) Braden T. Tierney et al.   Cell Host & Microbe

Suppression of gut dysbiosis by Bifidobacterium longum alleviates cognitive decline in 5XFAD transgenic and aged mice

(2019) Hae-Ji Lee et al.   Scientific Reports

Integrated Analyses of Microbiome and Longitudinal Metabolome Data Reveal Microbial-Host Interactions on Sulfur Metabolism in Parkinson’s Disease

(2019) Johannes Hertel et al.   Cell Reports

Short-Chain Fatty Acids Improve Poststroke Recovery via Immunological Mechanisms

(2019) Rebecca Sadler et al.   JOURNAL OF NEUROSCIENCE

Differences in fecal microbial metabolites and microbiota of children with autism spectrum disorders

(2018) Dae-Wook Kang et al.   ANAEROBE

Ketamine and ketamine metabolites as novel estrogen receptor ligands: Induction of cytochrome P450 and AMPA glutamate receptor gene expression

(2018) Ming-Fen Ho et al.   BIOCHEMICAL PHARMACOLOGY

Analysis of polyamine biosynthetic- and transport ability of human indigenous Bifidobacterium

(2018) Yuta Sugiyama et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Dysbiosis of microbiome and probiotic treatment in a genetic model of autism spectrum disorders

(2018) Laure Tabouy et al.   BRAIN BEHAVIOR AND IMMUNITY

Neurotransmitter modulation by the gut microbiota

(2018) Philip Strandwitz   BRAIN RESEARCH

The Gut Microbiota Mediates the Anti-Seizure Effects of the Ketogenic Diet

(2018) Christine A. Olson et al.   CELL

Influence of 4-week multi-strain probiotic administration on resting-state functional connectivity in healthy volunteers

(2018) Deepika Bagga et al.   EUROPEAN JOURNAL OF NUTRITION

Microbiome-Gut-Brain Axis and Toll-Like Receptors in Parkinson’s Disease

(2018) Valentina Caputi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

ThedesAanddesBgenes fromClostridium scindensATCC 35704 encode steroid-17,20-desmolase

(2018) Saravanan Devendran et al.   JOURNAL OF LIPID RESEARCH

Developmental effects of androgens in the human brain

(2018) T.-V. Nguyen   JOURNAL OF NEUROENDOCRINOLOGY

Antibiotics protect against EAE by increasing regulatory and anti-inflammatory cells

(2018) Hilary A. Seifert et al.   METABOLIC BRAIN DISEASE

Microglial control of astrocytes in response to microbial metabolites

(2018) Veit Rothhammer et al.   NATURE

Rapamycin relieves anxious emotion and synaptic plasticity deficits induced by hindlimb unloading in mice

(2018) Baohui Zhai et al.   NEUROSCIENCE LETTERS

Screening of quorum sensing peptides for biological effects in neuronal cells

(2018) Yorick Janssens et al.   PEPTIDES

Reduced microbiome alpha diversity in young patients with ADHD

(2018) Alexander Prehn-Kristensen et al.   PLoS One

Gut microbiota regulates maturation of the adult enteric nervous system via enteric serotonin networks

(2018) Filipe De Vadder et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Inflammation-Centric View of Neurological Disease: Beyond the Neuron

(2018) Stephen D. Skaper et al.   Frontiers in Cellular Neuroscience

Epigenetic modulation of inflammation and synaptic plasticity promotes resilience against stress in mice

(2018) Jun Wang et al.   Nature Communications

Glutamate and GABA in autism spectrum disorder—a translational magnetic resonance spectroscopy study in man and rodent models

(2018) Jamie Horder et al.   Translational Psychiatry

Indole, a Signaling Molecule Produced by the Gut Microbiota, Negatively Impacts Emotional Behaviors in Rats

(2018) Mathilde Jaglin et al.   Frontiers in Neuroscience

Steroid Transport, Local Synthesis, and Signaling within the Brain: Roles in Neurogenesis, Neuroprotection, and Sexual Behaviors

(2018) Nicolas Diotel et al.   Frontiers in Neuroscience

The Gut Microbiota Regulates Endocrine Vitamin D Metabolism through Fibroblast Growth Factor 23

(2018) Stephanie A. Bora et al.   Frontiers in Immunology

Effects of Oligosaccharides From Morinda officinalis on Gut Microbiota and Metabolome of APP/PS1 Transgenic Mice

(2018) Yang Xin et al.   Frontiers in Neurology

Microbiome–host systems interactions: protective effects of propionate upon the blood–brain barrier

(2018) Lesley Hoyles et al.   Microbiome

Enterochromaffin 5-HT cells – A major target for GLP-1 and gut microbial metabolites

(2018) Mari L. Lund et al.   Molecular Metabolism

Sodium Butyrate Improves Memory Function in an Alzheimer's Disease Mouse Model When Administered at an Advanced Stage of Disease Progression

(2018) Nambirajan Govindarajan et al.   JOURNAL OF ALZHEIMERS DISEASE

Cocoa Extracts Reduce Oligomerization of Amyloid-β: Implications for Cognitive Improvement in Alzheimer's Disease

(2018) Jun Wang et al.   JOURNAL OF ALZHEIMERS DISEASE

Microbiota influence the development of the brain and behaviors in C57BL/6J mice

(2018) Jing Lu et al.   PLoS One

Gut Microbiota and Relevant Metabolites Analysis in Alcohol Dependent Mice

(2018) Guanhao Wang et al.   Frontiers in Microbiology

Gut microbiota regulates mouse behaviors through glucocorticoid receptor pathway genes in the hippocampus

(2018) Yuanyuan Luo et al.   Translational Psychiatry

An update on the human and animal enteric pathogen Clostridium perfringens

(2018) Raymond Kiu et al.   Emerging Microbes & Infections

Short-chain fatty acids and gut microbiota in multiple sclerosis

(2018) Pernille Melbye et al.   ACTA NEUROLOGICA SCANDINAVICA

Altered bile acid profile in mild cognitive impairment and Alzheimer's disease: Relationship to neuroimaging and CSF biomarkers

(2018) Kwangsik Nho et al.   Alzheimers & Dementia

Altered bile acid profile associates with cognitive impairment in Alzheimer's disease—An emerging role for gut microbiome

(2018) Siamak MahmoudianDehkordi et al.   Alzheimers & Dementia

Prenatal Programming of Neuroendocrine System Development by Lipopolysaccharide: Long-Term Effects

(2018) Marina Izvolskaia et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mechanisms Underlying Microbial-Mediated Changes in Social Behavior in Mouse Models of Autism Spectrum Disorder

(2018) Martina Sgritta et al.   NEURON

The valproic acid rat model of autism presents with gut bacterial dysbiosis similar to that in human autism

(2018) Fang Liu et al.   Molecular Autism

Estrogen-mediated gut microbiome alterations influence sexual dimorphism in metabolic syndrome in mice

(2018) Kanakaraju Kaliannan et al.   Microbiome

GABA-modulating bacteria of the human gut microbiota

(2018) Philip Strandwitz et al.   Nature Microbiology

Gut microbiota functions: metabolism of nutrients and other food components

(2017) Ian Rowland et al.   EUROPEAN JOURNAL OF NUTRITION

Ferulic acid exerts neuroprotective effects against cerebral ischemia/reperfusion-induced injury via antioxidant and anti-apoptotic mechanisms in vitro and in vivo

(2017) Zhongkun Ren et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

TUDCA: An Agonist of the Bile Acid Receptor GPBAR1/TGR5 With Anti-Inflammatory Effects in Microglial Cells

(2017) Natalia Yanguas-Casás et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Bacterial Signaling to the Nervous System through Toxins and Metabolites

(2017) Nicole J. Yang et al.   JOURNAL OF MOLECULAR BIOLOGY

Estrogen–gut microbiome axis: Physiological and clinical implications

(2017) James M. Baker et al.   MATURITAS

The microbiome regulates amygdala-dependent fear recall

(2017) A E Hoban et al.   MOLECULAR PSYCHIATRY

Resveratrol and Grape Extract-loaded Solid Lipid Nanoparticles for the Treatment of Alzheimer’s Disease

(2017) Joana Loureiro et al.   MOLECULES

Endothelial TLR4 and the microbiome drive cerebral cavernous malformations

(2017) Alan T. Tang et al.   NATURE

A gut bacterial pathway metabolizes aromatic amino acids into nine circulating metabolites

(2017) Dylan Dodd et al.   NATURE

Agmatine ameliorates type 2 diabetes induced-Alzheimer's disease-like alterations in high-fat diet-fed mice via reactivation of blunted insulin signalling

(2017) Somang Kang et al.   NEUROPHARMACOLOGY

Stress-related regulation of the kynurenine pathway: Relevance to neuropsychiatric and degenerative disorders

(2017) Katherine O'Farrell et al.   NEUROPHARMACOLOGY

Trial of Minocycline in a Clinically Isolated Syndrome of Multiple Sclerosis

(2017) Luanne M. Metz et al.   NEW ENGLAND JOURNAL OF MEDICINE

Structural basis for the regulation of β-glucuronidase expression by human gut Enterobacteriaceae

(2017) Michael S. Little et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chemical transformation of xenobiotics by the human gut microbiota

(2017) Nitzan Koppel et al.   SCIENCE

Ferulic acid reverses depression-like behavior and oxidative stress induced by chronic corticosterone treatment in mice

(2017) Ana Lúcia Bertarello Zeni et al.   STEROIDS

Low-dose penicillin in early life induces long-term changes in murine gut microbiota, brain cytokines and behavior

(2017) Sophie Leclercq et al.   Nature Communications

Human Gut-Derived Commensal Bacteria Suppress CNS Inflammatory and Demyelinating Disease

(2017) Ashutosh Mangalam et al.   Cell Reports

The role of microbial amyloid in neurodegeneration

(2017) Robert P. Friedland et al.   PLoS Pathogens

Microbiota Modulate Anxiety-Like Behavior and Endocrine Abnormalities in Hypothalamic-Pituitary-Adrenal Axis

(2017) Ran Huo et al.   Frontiers in Cellular and Infection Microbiology

Bile Acid Signaling Pathways from the Enterohepatic Circulation to the Central Nervous System

(2017) Kim L. Mertens et al.   Frontiers in Neuroscience

Indoxyl Sulfate Affects Glial Function Increasing Oxidative Stress and Neuroinflammation in Chronic Kidney Disease: Interaction between Astrocytes and Microglia

(2017) Simona Adesso et al.   Frontiers in Pharmacology

Visceral Inflammation and Immune Activation Stress the Brain

(2017) Peter Holzer et al.   Frontiers in Immunology

Microbiota Transfer Therapy alters gut ecosystem and improves gastrointestinal and autism symptoms: an open-label study

(2017) Dae-Wook Kang et al.   Microbiome

Microbiota-related Changes in Bile Acid & Tryptophan Metabolism are Associated with Gastrointestinal Dysfunction in a Mouse Model of Autism

(2017) Anna V. Golubeva et al.   EBioMedicine

The Human Microbiota in Health and Disease

(2017) Baohong Wang et al.   Engineering

Bioavailability of Gallic Acid and Catechins from Grape Seed Polyphenol Extract is Improved by Repeated Dosing in Rats: Implications for Treatment in Alzheimer's Disease

(2017) Mario G. Ferruzzi et al.   JOURNAL OF ALZHEIMERS DISEASE

Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasiveness

(2017) Michiru Nishita et al.   Scientific Reports

Lipopolysaccharide enters the rat brain by a lipoprotein-mediated transport mechanism in physiological conditions

(2017) Alejandra Vargas-Caraveo et al.   Scientific Reports

Gut microbiome alterations in Alzheimer’s disease

(2017) Nicholas M. Vogt et al.   Scientific Reports

Neuroprotective effects of intravenous transplantation of bone marrow mononuclear cells from 5-fluorouracil pre-treated rats on ischemic stroke

(2016) Y. Li et al.   BEHAVIOURAL BRAIN RESEARCH

Organoids as an ex vivo model for studying the serotonin system in the murine small intestine and colon epithelium

(2016) Takeshi Tsuruta et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cognitive impairment by antibiotic-induced gut dysbiosis: Analysis of gut microbiota-brain communication

(2016) Esther E. Fröhlich et al.   BRAIN BEHAVIOR AND IMMUNITY

The potential health effects of dietary phytoestrogens

(2016) Ivonne M C M Rietjens et al.   BRITISH JOURNAL OF PHARMACOLOGY

Microbial Reconstitution Reverses Maternal Diet-Induced Social and Synaptic Deficits in Offspring

(2016) Shelly A. Buffington et al.   CELL

Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease

(2016) Timothy R. Sampson et al.   CELL

From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites

(2016) Ara Koh et al.   CELL

LPS-induced Murine Neuroinflammation Model: Main Features and Suitability for Pre-clinical Assessment of Nutraceuticals

(2016) Miryam Nava Catorce et al.   Current Neuropharmacology

Expanding role of gut microbiota in lipid metabolism

(2016) Anatole Ghazalpour et al.   CURRENT OPINION IN LIPIDOLOGY

Estrogens, Neuroinflammation, and Neurodegeneration

(2016) Alessandro Villa et al.   ENDOCRINE REVIEWS

Adult microbiota-deficient mice have distinct dendritic morphological changes: differential effects in the amygdala and hippocampus

(2016) Pauline Luczynski et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Effects of bile acids on neurological function and disease

(2016) Matthew McMillin et al.   FASEB JOURNAL

Nudging oligodendrocyte intrinsic signaling to remyelinate and repair: Estrogen receptor ligand effects

(2016) Anna J. Khalaj et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

HDAC Inhibitor Sodium Butyrate-Mediated Epigenetic Regulation Enhances Neuroprotective Function of Microglia During Ischemic Stroke

(2016) Radhika Patnala et al.   MOLECULAR NEUROBIOLOGY

The bacterial peptidoglycan-sensing molecule Pglyrp2 modulates brain development and behavior

(2016) T Arentsen et al.   MOLECULAR PSYCHIATRY

Gut microbiome remodeling induces depressive-like behaviors through a pathway mediated by the host’s metabolism

(2016) P Zheng et al.   MOLECULAR PSYCHIATRY

Diet–microbiota interactions as moderators of human metabolism

(2016) Justin L. Sonnenburg et al.   NATURE

Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor

(2016) Veit Rothhammer et al.   NATURE MEDICINE

GABA-producing Bifidobacterium dentium modulates visceral sensitivity in the intestine

(2016) K. Pokusaeva et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Behavioural and neurochemical consequences of chronic gut microbiota depletion during adulthood in the rat

(2016) A.E. Hoban et al.   NEUROSCIENCE

Obeticholic acid, a synthetic bile acid agonist of the farnesoid X receptor, attenuates experimental autoimmune encephalomyelitis

(2016) Peggy P. Ho et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alterations of the human gut microbiome in multiple sclerosis

(2016) Sushrut Jangi et al.   Nature Communications

Microbial metabolism of dietary components to bioactive metabolites: opportunities for new therapeutic interventions

(2016) Linda S. Zhang et al.   Genome Medicine

Microbiota-driven transcriptional changes in prefrontal cortex override genetic differences in social behavior

(2016) Mar Gacias et al.   eLife

Regulation of prefrontal cortex myelination by the microbiota

(2016) A E Hoban et al.   Translational Psychiatry

Bifidobacterium longum 1714 as a translational psychobiotic: modulation of stress, electrophysiology and neurocognition in healthy volunteers

(2016) A P Allen et al.   Translational Psychiatry

Interplay between microbial d-amino acids and host d-amino acid oxidase modifies murine mucosal defence and gut microbiota

(2016) Jumpei Sasabe et al.   Nature Microbiology

Exposure to the Functional Bacterial Amyloid Protein Curli Enhances Alpha-Synuclein Aggregation in Aged Fischer 344 Rats and Caenorhabditis elegans

(2016) Shu G. Chen et al.   Scientific Reports

Alterations of the Host Microbiome Affect Behavioral Responses to Cocaine

(2016) Drew D. Kiraly et al.   Scientific Reports

Fate of Microbial Metabolites of Dietary Polyphenols in Rats: Is the Brain Their Target Destination?

(2015) Mattia Gasperotti et al.   ACS Chemical Neuroscience

Gut microbiota depletion from early adolescence in mice: Implications for brain and behaviour

(2015) Lieve Desbonnet et al.   BRAIN BEHAVIOR AND IMMUNITY

Altered fecal microbiota composition in patients with major depressive disorder

(2015) Haiyin Jiang et al.   BRAIN BEHAVIOR AND IMMUNITY

A randomized controlled trial to test the effect of multispecies probiotics on cognitive reactivity to sad mood

(2015) Laura Steenbergen et al.   BRAIN BEHAVIOR AND IMMUNITY

Phenolic sulfates as new and highly abundant metabolites in human plasma after ingestion of a mixed berry fruit purée

(2015) Rui C. Pimpão et al.   BRITISH JOURNAL OF NUTRITION

Indigenous Bacteria from the Gut Microbiota Regulate Host Serotonin Biosynthesis

(2015) Jessica M. Yano et al.   CELL

The Gut Microbiome Contributes to a Substantial Proportion of the Variation in Blood LipidsNovelty and Significance

(2015) Jingyuan Fu et al.   CIRCULATION RESEARCH

Anterior cingulate Glutamate–Glutamine cycle metabolites are altered in euthymic bipolar I disorder

(2015) Márcio Gerhardt Soeiro-de-Souza et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Gut microbes promote colonic serotonin production through an effect of short-chain fatty acids on enterochromaffin cells

(2015) Christopher S. Reigstad et al.   FASEB JOURNAL

Untargeted Plasma Metabolomics Identifies Endogenous Metabolite with Drug-like Properties in Chronic Animal Model of Multiple Sclerosis

(2015) Laila M. Poisson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TGR5 signaling reduces neuroinflammation during hepatic encephalopathy

(2015) Matthew McMillin et al.   JOURNAL OF NEUROCHEMISTRY

Investigation of the Association Between the Fecal Microbiota and Breast Cancer in Postmenopausal Women: a Population-Based Case-Control Pilot Study

(2015) James J. Goedert et al.   JNCI-Journal of the National Cancer Institute

Plasma bioavailability and regional brain distribution of polyphenols from apple/grape seed and bilberry extracts in a young swine model

(2015) Tzu-Ying Chen et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Role of intestinal microbiota in the generation of polyphenol-derived phenolic acid mediated attenuation of Alzheimer's disease β-amyloid oligomerization

(2015) Dongjie Wang et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Host microbiota constantly control maturation and function of microglia in the CNS

(2015) Daniel Erny et al.   NATURE NEUROSCIENCE

Novel application of brain-targeting polyphenol compounds in sleep deprivation-induced cognitive dysfunction

(2015) Wei Zhao et al.   NEUROCHEMISTRY INTERNATIONAL

Effects of sodium butyrate on aversive memory in rats submitted to sepsis

(2015) Amanda V. Steckert et al.   NEUROSCIENCE LETTERS

PRR-signaling pathways: Learning from microbial tactics

(2015) Gernot Sellge et al.   SEMINARS IN IMMUNOLOGY

Genome architecture of Lactobacillus plantarum PS128, a probiotic strain with potential immunomodulatory activity

(2015) Wei-Hsien Liu et al.   Gut Pathogens

Bioavailability of Dietary Polyphenols and Gut Microbiota Metabolism: Antimicrobial Properties

(2015) Laura Marín et al.   Biomed Research International

Investigation of the Association Between the Fecal Microbiota and Breast Cancer in Postmenopausal Women: a Population-Based Case-Control Pilot Study

(2015) James J. Goedert et al.   JNCI-Journal of the National Cancer Institute

Systematic genome assessment of B-vitamin biosynthesis suggests co-operation among gut microbes

(2015) Stefanía Magnúsdóttir et al.   Frontiers in Genetics

Urinaryp-cresol is elevated in young French children with autism spectrum disorder: a replication study

(2014) Stefano Gabriele et al.   BIOMARKERS

Sphingolipids from a Symbiotic Microbe Regulate Homeostasis of Host Intestinal Natural Killer T Cells

(2014) Dingding An et al.   CELL

Associations of the Fecal Microbiome With Urinary Estrogens and Estrogen Metabolites in Postmenopausal Women

(2014) Barbara J. Fuhrman et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Sodium Butyrate Prevents Memory Impairment by Re-establishing BDNF and GDNF Expression in Experimental Pneumococcal Meningitis

(2014) Tatiana Barichello et al.   MOLECULAR NEUROBIOLOGY

Glycoursodeoxycholic Acid Reduces Matrix Metalloproteinase-9 and Caspase-9 Activation in a Cellular Model of Superoxide Dismutase-1 Neurodegeneration

(2014) Ana Rita Vaz et al.   MOLECULAR NEUROBIOLOGY

Gut microbiota are related to Parkinson's disease and clinical phenotype

(2014) Filip Scheperjans et al.   MOVEMENT DISORDERS

Estrogen Receptors, the Hippocampus, and Memory

(2014) Linda A. Bean et al.   NEUROSCIENTIST

The gut microbiota influences blood-brain barrier permeability in mice

(2014) V. Braniste et al.   Science Translational Medicine

Differential Modulation by Akkermansia muciniphila and Faecalibacterium prausnitzii of Host Peripheral Lipid Metabolism and Histone Acetylation in Mouse Gut Organoids

(2014) S. Lukovac et al.   mBio

The short-chain fatty acid acetate reduces appetite via a central homeostatic mechanism

(2014) Gary Frost et al.   Nature Communications

Androgen modulation of social decision-making mechanisms in the brain: an integrative and embodied perspective

(2014) Gonçalo A. Oliveira et al.   Frontiers in Neuroscience

Synbiotic consumption changes the metabolism and composition of the gut microbiota in older people and modifies inflammatory processes: a randomised, double-blind, placebo-controlled crossover study

(2013) S. Macfarlane et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

In vivo and in vitro metabolism of trans-resveratrol by human gut microbiota

(2013) Lisa M Bode et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Species-Dependent Blood-Brain Barrier Disruption of Lipopolysaccharide: Amelioration by ColistinIn VitroandIn Vivo

(2013) Liang Jin et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Agmatine attenuates acquisition but not the expression of ethanol conditioned place preference in mice

(2013) Shaikh M. Sameer et al.   BEHAVIOURAL PHARMACOLOGY

β-Arrestin 2 Mediates G Protein-Coupled Receptor 43 Signals to Nuclear Factor-κB

(2013) Su Ui Lee et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Microbiota Modulate Behavioral and Physiological Abnormalities Associated with Neurodevelopmental Disorders

(2013) Elaine Y. Hsiao et al.   CELL

Consumption of Fermented Milk Product With Probiotic Modulates Brain Activity

(2013) Kirsten Tillisch et al.   GASTROENTEROLOGY

Clostridium scindens: a human gut microbe with a high potential to convert glucocorticoids into androgens

(2013) Jason M. Ridlon et al.   JOURNAL OF LIPID RESEARCH

Anti-inflammatory Effect of Acetylpuerarin on Eicosanoid Signaling Pathway in Primary Rat Astrocytes

(2013) Yanxiao Xiang et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Microbiota is essential for social development in the mouse

(2013) L Desbonnet et al.   MOLECULAR PSYCHIATRY

Restoring polyamines protects from age-induced memory impairment in an autophagy-dependent manner

(2013) Varun K Gupta et al.   NATURE NEUROSCIENCE

Prebiotic feeding elevates central brain derived neurotrophic factor, N-methyl-d-aspartate receptor subunits and d-serine

(2013) Helene M. Savignac et al.   NEUROCHEMISTRY INTERNATIONAL

Ferulic Acid Is a Nutraceutical β-Secretase Modulator That Improves Behavioral Impairment and Alzheimer-like Pathology in Transgenic Mice

(2013) Takashi Mori et al.   PLoS One

Estrogen receptor (ER)   expression in oligodendrocytes is required for attenuation of clinical disease by an ER  ligand

(2013) A. J. Khalaj et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sex Differences in the Gut Microbiome Drive Hormone-Dependent Regulation of Autoimmunity

(2013) J. G. M. Markle et al.   SCIENCE

Vitamin K and Brain Function

(2013) Guylaine Ferland   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Bioavailability of dietary (poly)phenols: a study with ileostomists to discriminate between absorption in small and large intestine

(2013) Gina Borges et al.   Food & Function

The Interplay Between Fiber and the Intestinal Microbiome in the Inflammatory Response

(2013) Shiu-Ming Kuo   Advances in Nutrition

The clinical antidepressant effect of exogenous agmatine is not reversed by parachlorophenylalanine: a pilot study

(2012) Baron Shopsin   ACTA NEUROPSYCHIATRICA

Critical role of gut microbiota in the production of biologically active, free catecholamines in the gut lumen of mice

(2012) Yasunari Asano et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Maternal immune activation yields offspring displaying mouse versions of the three core symptoms of autism

(2012) Natalia V. Malkova et al.   BRAIN BEHAVIOR AND IMMUNITY

Dysfunctional hippocampal activity affects emotion and cognition in mood disorders

(2012) Teresa Femenía et al.   BRAIN RESEARCH

Bacteria as vitamin suppliers to their host: a gut microbiota perspective

(2012) Jean Guy LeBlanc et al.   CURRENT OPINION IN BIOTECHNOLOGY

Phylogenetic distribution of genes encoding β-glucuronidase activity in human colonic bacteria and the impact of diet on faecal glycosidase activities

(2012) Freda M. McIntosh et al.   ENVIRONMENTAL MICROBIOLOGY

Identification of brain-targeted bioactive dietary quercetin-3-O-glucuronide as a novel intervention for Alzheimer's disease

(2012) Lap Ho et al.   FASEB JOURNAL

α5β1-integrins are sensors for tauroursodeoxycholic acid in hepatocytes

(2012) Holger Gohlke et al.   HEPATOLOGY

The gut microbiota regulates bone mass in mice

(2012) Klara Sjögren et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Carbamate Derivatives of Indolines as Cholinesterase Inhibitors and Antioxidants for the Treatment of Alzheimer’s Disease

(2012) Inessa Yanovsky et al.   JOURNAL OF MEDICINAL CHEMISTRY

Brain-Targeted Proanthocyanidin Metabolites for Alzheimer's Disease Treatment

(2012) J. Wang et al.   JOURNAL OF NEUROSCIENCE

Fecal microbial determinants of fecal and systemic estrogens and estrogen metabolites: a cross-sectional study

(2012) Roberto Flores et al.   Journal of Translational Medicine

The microbiome-gut-brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner

(2012) G Clarke et al.   MOLECULAR PSYCHIATRY

Structure, function and diversity of the healthy human microbiome

(2012)   NATURE

The human microbiome: at the interface of health and disease

(2012) Ilseung Cho et al.   NATURE REVIEWS GENETICS

Kynurenines in the mammalian brain: when physiology meets pathology

(2012) Robert Schwarcz et al.   NATURE REVIEWS NEUROSCIENCE

Effects of antidepressants on alternations in serum cytokines and depressive-like behavior in mice after lipopolysaccharide administration

(2012) Yuta Ohgi et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Resveratrol Inhibits Inflammatory Responses via the Mammalian Target of Rapamycin Signaling Pathway in Cultured LPS-Stimulated Microglial Cells

(2012) Lian-Mei Zhong et al.   PLoS One

Waking Action of Ursodeoxycholic Acid (UDCA) Involves Histamine and GABAA Receptor Block

(2012) Yevgenij Yanovsky et al.   PLoS One

Impact of Intestinal Microbiota on Intestinal Luminal Metabolome

(2012) Mitsuharu Matsumoto et al.   Scientific Reports

Role of Sex Steroid Hormones in Bacterial-Host Interactions

(2012) Elizabeth García-Gómez et al.   Biomed Research International

Suppression of the HPA axis during extrahepatic biliary obstruction induces cholangiocyte proliferation in the rat

(2011) Matthew Quinn et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Lipopolysaccharide-Induced Sickness Behaviour Evaluated in Different Models of Anxiety and Innate Fear in Rats

(2011) Gabriel S. Bassi et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Microbiome and Malignancy

(2011) Claudia S. Plottel et al.   Cell Host & Microbe

Toll-like receptors in health and disease in the brain: mechanisms and therapeutic potential

(2011) Mark L. Hanke et al.   CLINICAL SCIENCE

Labeled Acetate as a Marker of Astrocytic Metabolism

(2011) Matthias T Wyss et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination

(2011) Kerstin Berer et al.   NATURE

GSPE interferes with tau aggregation in vivo: implication for treating tauopathy

(2011) Ismael Santa-Maria et al.   NEUROBIOLOGY OF AGING

The anxiolytic effect of Bifidobacterium longum NCC3001 involves vagal pathways for gut-brain communication

(2011) P. Bercik et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Memory impairment induced by brain iron overload is accompanied by reduced H3K9 acetylation and ameliorated by sodium butyrate

(2011) P.F. da Silva et al.   NEUROSCIENCE

The bile steroid chenodeoxycholate is a potent antagonist at NMDA and GABAA receptors

(2011) S.R. Schubring et al.   NEUROSCIENCE LETTERS

Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve

(2011) J. A. Bravo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Normal gut microbiota modulates brain development and behavior

(2011) R. D. Heijtz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modulation of Mucosal Immune Response, Tolerance, and Proliferation in Mice Colonized by the Mucin-Degrader Akkermansia muciniphila

(2011) Muriel Derrien et al.   Frontiers in Microbiology

Bacterial degradation of bile salts

(2010) Bodo Philipp   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Protection of dopaminergic cells from MPP+-mediated toxicity by histone deacetylase inhibition

(2010) Sarah K. Kidd et al.   BRAIN RESEARCH

Assessment of psychotropic-like properties of a probiotic formulation ( Lactobacillus helveticus R0052 and Bifidobacterium longum R0175) in rats and human subjects

(2010) Michaël Messaoudi et al.   BRITISH JOURNAL OF NUTRITION

Agmatine, an endogenous imidazoline receptor ligand modulates ethanol anxiolysis and withdrawal anxiety in rats

(2010) Brijesh G Taksande et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The bile acid receptor TGR5 (Gpbar-1) acts as a neurosteroid receptor in brain

(2010) Verena Keitel et al.   GLIA

Bile acids modulate glucocorticoid metabolism and the hypothalamic–pituitary–adrenal axis in obstructive jaundice

(2010) Alison D. McNeilly et al.   JOURNAL OF HEPATOLOGY

On the mechanism of accumulation of cholestanol in the brain of mice with a disruption of sterol 27-hydroxylase

(2010) Ann Båvner et al.   JOURNAL OF LIPID RESEARCH

TLR2 activation inhibits embryonic neural progenitor cell proliferation

(2010) Eitan Okun et al.   JOURNAL OF NEUROCHEMISTRY

Reduced anxiety-like behavior and central neurochemical change in germ-free mice

(2010) K. M. Neufeld et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Genetic association studies of glutamate, GABA and related genes in schizophrenia and bipolar disorder: A decade of advance

(2010) Suat Ying Tan Cherlyn et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

A metagenomic  -glucuronidase uncovers a core adaptive function of the human intestinal microbiome

(2010) K. Gloux et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bacterial Toxins and the Nervous System: Neurotoxins and Multipotential Toxins Interacting with Neuronal Cells

(2010) Michel R. Popoff et al.   Toxins

Crystal Structure of the Acid-Induced Arginine Decarboxylase fromEscherichia coli: Reversible Decamer Assembly Controls Enzyme Activity

(2009) Juni Andréll et al.   BIOCHEMISTRY

Putting the ‘HAT’ back on survival signalling: the promises and challenges of HDAC inhibition in the treatment of neurological conditions

(2009) Sama F Sleiman et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Structure and Regulation of the gab Gene Cluster, Involved in the  -Aminobutyric Acid Shunt, Are Controlled by a  54 Factor in Bacillus thuringiensis

(2009) L. Zhu et al.   JOURNAL OF BACTERIOLOGY

Role of Gut Commensal Microflora in the Development of Experimental Autoimmune Encephalomyelitis

(2009) J. Ochoa-Reparaz et al.   JOURNAL OF IMMUNOLOGY

Bile acids as regulatory molecules

(2009) Phillip B. Hylemon et al.   JOURNAL OF LIPID RESEARCH

The gut microbiota modulates host energy and lipid metabolism in mice

(2009) Vidya R. Velagapudi et al.   JOURNAL OF LIPID RESEARCH

Common CYP7A1 promoter polymorphism associated with risk of neuromyelitis optica

(2009) Ho Jin Kim et al.   NEUROBIOLOGY OF DISEASE

Inhibitors of Class 1 Histone Deacetylases Reverse Contextual Memory Deficits in a Mouse Model of Alzheimer's Disease

(2009) Mark Kilgore et al.   NEUROPSYCHOPHARMACOLOGY

Histone deactylase inhibition combined with behavioral therapy enhances learning and memory following traumatic brain injury

(2009) P.K. Dash et al.   NEUROSCIENCE

Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites

(2009) W. R. Wikoff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Luminal regulation of normal and neoplastic human EC cell serotonin release is mediated by bile salts, amines, tastants, and olfactants

(2008) Mark Kidd et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Intracerebroventricular injections of the enteric bacterial metabolic product propionic acid impair cognition and sensorimotor ability in the Long–Evans rat: Further development of a rodent model of autism

(2008) Sandy R. Shultz et al.   BEHAVIOURAL BRAIN RESEARCH

Distribution of β-glucosidase and β-glucuronidase activity and of β-glucuronidase gene gus in human colonic bacteria

(2008) Marta Dabek et al.   FEMS MICROBIOLOGY ECOLOGY

Lipopolysaccharide-induced depressive-like behavior is mediated by indoleamine 2,3-dioxygenase activation in mice

(2008) J C O'Connor et al.   MOLECULAR PSYCHIATRY

An Alternative Menaquinone Biosynthetic Pathway Operating in Microorganisms

(2008) T. Hiratsuka et al.   SCIENCE

Trace amine-associated receptors and their ligands

(2006) R Zucchi et al.   BRITISH JOURNAL OF PHARMACOLOGY