The vicious circle of hypometabolism in neurodegenerative diseases: Ways and mechanisms of metabolic correction

Inflammation in epileptogenesis after traumatic brain injury

(2017) Kyria M. Webster et al.   Journal of Neuroinflammation

Selfish brain and selfish immune system interplay: A theoretical framework for metabolic comorbidities of mood disorders

(2017) Ana Sayuri Yamagata et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

How does the ketogenic diet induce anti-seizure effects?

(2017) Jong M. Rho   NEUROSCIENCE LETTERS

Glucose deficit triggers tau pathology and synaptic dysfunction in a tauopathy mouse model

(2017) E Lauretti et al.   Translational Psychiatry

Brain Insulin-Like Growth Factor and Neurotrophin Resistance in Parkinson's Disease and Dementia with Lewy Bodies: Potential Role of Manganese Neurotoxicity

(2017) Ming Tong et al.   JOURNAL OF ALZHEIMERS DISEASE

An Integrative View of the Role of Oxidative Stress, Mitochondria and Insulin in Alzheimer's Disease

(2017) Paula I. Moreira et al.   JOURNAL OF ALZHEIMERS DISEASE

Oxidatively Modified Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) and Alzheimer's Disease: Many Pathways to Neurodegeneration

(2017) D. Allan Butterfield et al.   JOURNAL OF ALZHEIMERS DISEASE

The genetic background of Parkinson's disease: current progress and future prospects

(2016) K. Kalinderi et al.   ACTA NEUROLOGICA SCANDINAVICA

Toward a consensus recommendation for defining the asymptomatic-preclinical phases of putative Alzheimer's disease?

(2016) Zaven S. Khachaturian et al.   Alzheimers & Dementia

Incidence and impact of subclinical epileptiform activity in Alzheimer's disease

(2016) Keith A. Vossel et al.   ANNALS OF NEUROLOGY

Can ketones compensate for deteriorating brain glucose uptake during aging? Implications for the risk and treatment of Alzheimer's disease

(2016) Stephen C. Cunnane et al.   Annals of the New York Academy of Sciences

Parkinson's disease: Autoimmunity and neuroinflammation

(2016) Armando De Virgilio et al.   AUTOIMMUNITY REVIEWS

Risk of epilepsy in type 1 diabetes mellitus: a population-based cohort study

(2016) I-Ching Chou et al.   DIABETOLOGIA

Insulin Resistance and Neurodegeneration: Progress Towards the Development of New Therapeutics for Alzheimer’s Disease

(2016) Suzanne M. de la Monte   DRUGS

Amyloid-β suppresses AMP-activated protein kinase (AMPK) signaling and contributes to α-synuclein-induced cytotoxicity

(2016) Chih-Li Lin et al.   EXPERIMENTAL NEUROLOGY

Oxidative challenge in Alzheimer's disease: state of knowledge and future needs

(2016) Carlo Cervellati et al.   JOURNAL OF INVESTIGATIVE MEDICINE

Aerobic glycolysis during brain activation: adrenergic regulation and influence of norepinephrine on astrocytic metabolism

(2016) Gerald A. Dienel et al.   JOURNAL OF NEUROCHEMISTRY

Hippocampal α-Synuclein in Dementia with Lewy Bodies Contributes to Memory Impairment and Is Consistent with Spread of Pathology

(2016) David H. Adamowicz et al.   JOURNAL OF NEUROSCIENCE

The Cerebral Network of Parkinson's Tremor: An Effective Connectivity fMRI Study

(2016) Michiel F. Dirkx et al.   JOURNAL OF NEUROSCIENCE

KV7/M channels as targets for lipopolysaccharide-induced inflammatory neuronal hyperexcitability

(2016) Arik Tzour et al.   JOURNAL OF PHYSIOLOGY-LONDON

[18F]FDG PET Neuroimaging Predicts Pentylenetetrazole (PTZ) Kindling Outcome in Rats

(2016) Pablo Bascuñana et al.   MOLECULAR IMAGING AND BIOLOGY

Alternative Fuels in Epilepsy and Amyotrophic Lateral Sclerosis

(2016) Tesfaye W. Tefera et al.   NEUROCHEMICAL RESEARCH

13C metabolic flux analysis in neurons utilizing a model that accounts for hexose phosphate recycling within the pentose phosphate pathway

(2016) Hoda M. Gebril et al.   NEUROCHEMISTRY INTERNATIONAL

Inflammatory mediators in human epilepsy: A systematic review and meta-analysis

(2016) Evelien E. de Vries et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Human striatal recordings reveal abnormal discharge of projection neurons in Parkinson’s disease

(2016) Arun Singh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Brain aerobic glycolysis and motor adaptation learning

(2016) Benjamin J. Shannon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Insulin resistance and Parkinson’s disease: A new target for disease modification?

(2016) D. Athauda et al.   PROGRESS IN NEUROBIOLOGY

Oxidative stress: A major pathogenesis and potential therapeutic target of antioxidative agents in Parkinson’s disease and Alzheimer’s disease

(2016) Tianfang Jiang et al.   PROGRESS IN NEUROBIOLOGY

The Warburg Effect: How Does it Benefit Cancer Cells?

(2016) Maria V. Liberti et al.   TRENDS IN BIOCHEMICAL SCIENCES

Anti-Inflammatory Small Molecules To Treat Seizures and Epilepsy: From Bench to Bedside

(2016) Avijit Dey et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Mechanisms of Action of Antiseizure Drugs and the Ketogenic Diet

(2016) Michael A. Rogawski et al.   Cold Spring Harbor Perspectives in Medicine

Chronic Pyruvate Supplementation Increases Exploratory Activity and Brain Energy Reserves in Young and Middle-Aged Mice

(2016) Hennariikka Koivisto et al.   Frontiers in Aging Neuroscience

Can Ketones Help Rescue Brain Fuel Supply in Later Life? Implications for Cognitive Health during Aging and the Treatment of Alzheimer’s Disease

(2016) Stephen C. Cunnane et al.   Frontiers in Molecular Neuroscience

Triple-target treatment for Alzheimer’s: Correcting hypometabolism, oxidative stress, and neuroinflammation

(2015) Misha Zilberter et al.   Alzheimers & Dementia

Influence of microglial activation on neuronal function in Alzheimer's and Parkinson's disease dementia

(2015) Zhen Fan et al.   Alzheimers & Dementia

Neuronal hyperactivity - A key defect in Alzheimer's disease?

(2015) Marc Aurel Busche et al.   BIOESSAYS

Mitochondrial dysfunction: the missing link between aging and sporadic Alzheimer’s disease

(2015) Amandine Grimm et al.   BIOGERONTOLOGY

Cytosolic thiol switches regulating basic cellular functions: GAPDH as an information hub?

(2015) Thomas Hildebrandt et al.   BIOLOGICAL CHEMISTRY

Oxidative stress, mitochondrial dysfunction and neurodegenerative diseases; a mechanistic insight

(2015) Aashiq Hussain Bhat et al.   BIOMEDICINE & PHARMACOTHERAPY

Can the disease course in Parkinson’s disease be slowed?

(2015) Amos D. Korczyn et al.   BMC Medicine

Cellular and metabolic alterations in the hippocampus caused by insulin signalling dysfunction and its association with cognitive impairment during aging and Alzheimer's disease: studies in animal models

(2015) Erika Calvo-Ochoa et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Dietary therapy is not the best option for refractory nonsurgical epilepsy

(2015) María Magdalena Vaccarezza et al.   EPILEPSIA

Systemic pyruvate administration markedly reduces neuronal death and cognitive impairment in a rat model of Alzheimer's disease

(2015) Xiaonan Wang et al.   EXPERIMENTAL NEUROLOGY

FDG-PET and NeuN-GFAP Immunohistochemistry of Hippocampus at Different Phases of the Pilocarpine Model of Temporal Lobe Epilepsy

(2015) Liang Zhang et al.   International Journal of Medical Sciences

Early metabolic responses to lithium/pilocarpine-induced status epilepticus in rat brain

(2015) Imran Imran et al.   JOURNAL OF NEUROCHEMISTRY

Effects of ketone bodies in Alzheimer's disease in relation to neural hypometabolism, β-amyloid toxicity, and astrocyte function

(2015) Leif Hertz et al.   JOURNAL OF NEUROCHEMISTRY

The CardioMetabolic Health Alliance

(2015) Laurence S. Sperling et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Mitochondrial dysfunction and seizures: the neuronal energy crisis

(2015) Gábor Zsurka et al.   LANCET NEUROLOGY

Neuroinflammation in Alzheimer's disease

(2015) Michael T Heneka et al.   LANCET NEUROLOGY

PARP-1 involvement in neurodegeneration: A focus on Alzheimer’s and Parkinson’s diseases

(2015) Sara Martire et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Post-traumatic neurodegeneration and chronic traumatic encephalopathy

(2015) Daniel H. Daneshvar et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Metabolic Remodeling in Times of Stress: Who Shoots Faster than His Shadow?

(2015) Tobias P. Dick et al.   MOLECULAR CELL

Anaplerotic treatment of long-chain fat oxidation disorders with triheptanoin: Review of 15years Experience

(2015) Charles R. Roe et al.   MOLECULAR GENETICS AND METABOLISM

Amyloid deposition in Parkinson's disease and cognitive impairment: A systematic review

(2015) Myria Petrou et al.   MOVEMENT DISORDERS

Hippocampal insulin resistance and cognitive dysfunction

(2015) Geert Jan Biessels et al.   NATURE REVIEWS NEUROSCIENCE

PET Radioligands Reveal the Basis of Dementia in Parkinson's Disease and Dementia with Lewy Bodies

(2015) Stephen N. Gomperts et al.   Neurodegenerative Diseases

Alzheimer’s Pathogenesis and Its Link to the Mitochondrion

(2015) C. Simoncini et al.   Oxidative Medicine and Cellular Longevity

The restless brain: how intrinsic activity organizes brain function

(2015) M. E. Raichle   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Targeting LDH enzymes with a stiripentol analog to treat epilepsy

(2015) N. Sada et al.   SCIENCE

The Epileptic Thalamocortical Network is a Macroscopic Self-Sustained Oscillator: Evidence from Frequency-Locking Experiments in Rat Brains

(2015) J. L. Perez Velazquez et al.   Scientific Reports

Epileptogenesis

(2015) Asla Pitkänen et al.   Cold Spring Harbor Perspectives in Medicine

Low Cerebral Glucose Metabolism: A Potential Predictor for the Severity of Vascular Parkinsonism and Parkinson's Disease

(2015) Xu Yunqi et al.   Aging and Disease

Metabolic Risk Factors of Sporadic Alzheimer's Disease: Implications in the Pathology, Pathogenesis and Treatment

(2015) Sasanka Chakrabarti et al.   Aging and Disease

A unique array of neuroprotective effects of pyruvate in neuropathology

(2015) Yuri Zilberter et al.   Frontiers in Neuroscience

Methylglyoxal, the dark side of glycolysis

(2015) Igor Allaman et al.   Frontiers in Neuroscience

Aberrant insulin signaling in Alzheimer's disease: current knowledge

(2015) Gaurav Bedse et al.   Frontiers in Neuroscience

How does brain insulin resistance develop in Alzheimer's disease?

(2014) Fernanda G. De Felice et al.   Alzheimers & Dementia

Non-preferential fuelling of the Na+/K+-ATPase pump

(2014) Ignacio Fernández-Moncada et al.   BIOCHEMICAL JOURNAL

Brain metabolic dysfunction at the core of Alzheimer's disease

(2014) Suzanne M. de la Monte et al.   BIOCHEMICAL PHARMACOLOGY

The return of metabolism: biochemistry and physiology of the pentose phosphate pathway

(2014) Anna Stincone et al.   BIOLOGICAL REVIEWS

Oxidative stress, redox signalling and endothelial dysfunction in ageing-related neurodegenerative diseases: a role of NADPH oxidase 2

(2014) Sarah Cahill-Smith et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Synopsis on the Linkage of Alzheimer's and Parkinson's Disease with Chronic Diseases

(2014) Nasimudeen R. Jabir et al.   CNS Neuroscience & Therapeutics

Insulin Reverses the High-Fat Diet-Induced Increase in Brain A  and Improves Memory in an Animal Model of Alzheimer Disease

(2014) M. Vandal et al.   DIABETES

Glucose metabolism transporters and epilepsy: Only GLUT1 has an established role

(2014) Michael S. Hildebrand et al.   EPILEPSIA

Structural analysis of glyceraldehyde-3-phosphate dehydrogenase functional diversity

(2014) Michael A. Sirover   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Brain hypometabolism triggers PHF-like phosphorylation of tau, a major hallmark of Alzheimer’s disease pathology

(2014) Thomas Arendt et al.   JOURNAL OF NEURAL TRANSMISSION

Metabolism of stromal and immune cells in health and disease

(2014) Bart Ghesquière et al.   NATURE

System-based approaches to decode the molecular links in Parkinson's disease and diabetes

(2014) Jose A. Santiago et al.   NEUROBIOLOGY OF DISEASE

Epilepsy, energy deficiency and new therapeutic approaches including diet

(2014) Christopher A. Reid et al.   PHARMACOLOGY & THERAPEUTICS

Poly(ADP-ribose) polymerase-dependent energy depletion occurs through inhibition of glycolysis

(2014) S. A. Andrabi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Insulin resistance, selfish brain, and selfish immune system: an evolutionarily positively selected program used in chronic inflammatory diseases

(2014) Rainer H Straub   ARTHRITIS RESEARCH & THERAPY

The Role of Functional Neuroimaging in Pre-Surgical Epilepsy Evaluation

(2014) Francesca Pittau et al.   Frontiers in Neurology

The Alzheimer's disease mitochondrial cascade hypothesis: Progress and perspectives

(2013) Russell H. Swerdlow et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Alzheimer’s as a metabolic disease

(2013) Lloyd A. Demetrius et al.   BIOGERONTOLOGY

The role of inflammation in sporadic and familial Parkinson’s disease

(2013) Michela Deleidi et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Antiepileptics Topiramate and Levetiracetam Alleviate Behavioral Deficits and Reduce Neuropathology in APPswe/PS1dE9 Transgenic Mice

(2013) Jian-Quan Shi et al.   CNS Neuroscience & Therapeutics

Phenotypic Spectrum of Glucose Transporter Type 1 Deficiency Syndrome (Glut1 DS)

(2013) Toni S. Pearson et al.   Current Neurology and Neuroscience Reports

Shared cognitive and behavioral impairments in epilepsy and Alzheimer's disease and potential underlying mechanisms

(2013) Jeannie Chin et al.   EPILEPSY & BEHAVIOR

Targeting deficiencies in mitochondrial respiratory complex I and functional uncoupling exerts anti-seizure effects in a genetic model of temporal lobe epilepsy and in a model of acute temporal lobe seizures

(2013) Kristina A. Simeone et al.   EXPERIMENTAL NEUROLOGY

Inflammatory response of microglial BV-2 cells includes a glycolytic shift and is modulated by mitochondrial glucose-regulated protein 75/mortalin

(2013) Ludmila A. Voloboueva et al.   FEBS LETTERS

Mitochondrial involvement and oxidative stress in temporal lobe epilepsy

(2013) Shane Rowley et al.   FREE RADICAL BIOLOGY AND MEDICINE

Parkinson disease: from pathology to molecular disease mechanisms

(2013) David T. Dexter et al.   FREE RADICAL BIOLOGY AND MEDICINE

Ketosis Proportionately Spares Glucose Utilization in Brain

(2013) Yifan Zhang et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Glycolysis and Oxidative Phosphorylation in Neurons and Astrocytes during Network Activity in Hippocampal Slices

(2013) Anton I Ivanov et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

How Does the Ketogenic Diet Work? Four Potential Mechanisms

(2013) Nika N. Danial et al.   JOURNAL OF CHILD NEUROLOGY

The Role of Inflammatory and Oxidative Stress Mechanisms in the Pathogenesis of Parkinson’s Disease: Focus on Astrocytes

(2013) Rituraj Niranjan   MOLECULAR NEUROBIOLOGY

Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy

(2013) Chia-Chen Liu et al.   Nature Reviews Neurology

Dysregulation of glucose metabolism is an early event in sporadic Parkinson's disease

(2013) Laura Dunn et al.   NEUROBIOLOGY OF AGING

Oxidative stress, DNA damage, and the telomeric complex as therapeutic targets in acute neurodegeneration

(2013) Joshua A. Smith et al.   NEUROCHEMISTRY INTERNATIONAL

CREB regulates the expression of neuronal glucose transporter 3: a possible mechanism related to impaired brain glucose uptake in Alzheimer's disease

(2013) N. Jin et al.   NUCLEIC ACIDS RESEARCH

Tremor: Pathophysiology

(2013) Mark Hallett   PARKINSONISM & RELATED DISORDERS

Integrative Network Analysis Unveils Convergent Molecular Pathways in Parkinson's Disease and Diabetes

(2013) Jose A. Santiago et al.   PLoS One

Decoding Alzheimer's disease from perturbed cerebral glucose metabolism: Implications for diagnostic and therapeutic strategies

(2013) Zhichun Chen et al.   PROGRESS IN NEUROBIOLOGY

Seizures and Epileptiform Activity in the Early Stages of Alzheimer Disease

(2013) Keith A. Vossel et al.   JAMA Neurology

Cerebrovascular Effects of Apolipoprotein E

(2013) Berislav V. Zlokovic   JAMA Neurology

Combined in vivo and in silico investigations of activation of glycolysis in contracting skeletal muscle

(2012) J. P. J. Schmitz et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Parkinson's disease, insulin resistance and novel agents of neuroprotection

(2012) Iciar Aviles-Olmos et al.   BRAIN

The ketogenic diet increases brain glucose and ketone uptake in aged rats: A dual tracer PET and volumetric MRI study

(2012) Maggie Roy et al.   BRAIN RESEARCH

Roles of Glycogen Synthase Kinase 3 in Alzheimer’s Disease

(2012) Zhiyou Cai et al.   Current Alzheimer Research

Brain Insulin Resistance and Deficiency as Therapeutic Targets in Alzheimers Disease

(2012) Suzanne M. de la Monte   Current Alzheimer Research

The Role of Reactive Species in Epileptogenesis and Influence of Antiepileptic Drug Therapy on Oxidative Stress

(2012) Bostjan Martinc et al.   Current Neuropharmacology

Ketogenic diets

(2012) Eric H. Kossoff et al.   CURRENT OPINION IN NEUROLOGY

Targeting Oxidative Stress Component in the Therapeutics of Epilepsy

(2012) Faizul Azam et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Changes in glucose metabolism and metabolites during the epileptogenic process in the lithium-pilocarpine model of epilepsy

(2012) Eun Mi Lee et al.   EPILEPSIA

Hypometabolism precedes limbic atrophy and spontaneous recurrent seizures in a rat model of TLE

(2012) Bianca Jupp et al.   EPILEPSIA

MECHANISMS IN ENDOCRINOLOGY: Seizures and type 1 diabetes mellitus: current state of knowledge

(2012) Alberto Verrotti et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Mitochondrial defects and oxidative stress in Alzheimer disease and Parkinson disease

(2012) Michael H. Yan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Demonstrated brain insulin resistance in Alzheimer’s disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline

(2012) Konrad Talbot et al.   JOURNAL OF CLINICAL INVESTIGATION

Effects of hypoglycaemia on neuronal metabolism in the adult brain: role of alternative substrates to glucose

(2012) Ana I. Amaral   JOURNAL OF INHERITED METABOLIC DISEASE

Dietary energy substrates reverse early neuronal hyperactivity in a mouse model of Alzheimer's disease

(2012) Misha Zilberter et al.   JOURNAL OF NEUROCHEMISTRY

The many faces of insulin-like peptide signalling in the brain

(2012) Ana M. Fernandez et al.   NATURE REVIEWS NEUROSCIENCE

Mitochondrial dysfunction and oxidative stress in Parkinson's disease and monogenic parkinsonism

(2012) David N. Hauser et al.   NEUROBIOLOGY OF DISEASE

Activation of PARP by Oxidative Stress Induced by β-Amyloid: Implications for Alzheimer’s Disease

(2012) Rosella Abeti et al.   NEUROCHEMICAL RESEARCH

Energy depletion in seizures: Anaplerosis as a strategy for future therapies

(2012) Stjepana Kovac et al.   NEUROPHARMACOLOGY

Variant of TREM2 Associated with the Risk of Alzheimer's Disease

(2012) Thorlakur Jonsson et al.   NEW ENGLAND JOURNAL OF MEDICINE

TREM2 Variants in Alzheimer's Disease

(2012) Rita Guerreiro et al.   NEW ENGLAND JOURNAL OF MEDICINE

Oxidative Stress and Epilepsy: Literature Review

(2012) Carlos Clayton Torres Aguiar et al.   Oxidative Medicine and Cellular Longevity

Chronic Temporal Lobe Epilepsy Is Associated with Enhanced Alzheimer-Like Neuropathology in 3×Tg-AD Mice

(2012) Xiao-Xin Yan et al.   PLoS One

Levetiracetam suppresses neuronal network dysfunction and reverses synaptic and cognitive deficits in an Alzheimer's disease model

(2012) P. E. Sanchez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effect of Glutamate and Blood Glutamate Scavengers Oxaloacetate and Pyruvate on Neurological Outcome and Pathohistology of the Hippocampus after Traumatic Brain Injury in Rats

(2011) Alexander Zlotnik et al.   ANESTHESIOLOGY

β-amyloid activates PARP causing astrocytic metabolic failure and neuronal death

(2011) Rosella Abeti et al.   BRAIN

Brain glucose transporter (Glut3) haploinsufficiency does not impair mouse brain glucose uptake

(2011) Charles A. Stuart et al.   BRAIN RESEARCH

Abnormal tau, mitochondrial dysfunction, impaired axonal transport of mitochondria, and synaptic deprivation in Alzheimer's disease

(2011) P. Hemachandra Reddy   BRAIN RESEARCH

The ketogenic and related diets in adolescents and adults-A review

(2011) Natasha E. Payne et al.   EPILEPSIA

A perfect storm: Converging paths of epilepsy and Alzheimer’s dementia intersect in the hippocampal formation

(2011) Jeffrey Noebels   EPILEPSIA

Triheptanoin—A medium chain triglyceride with odd chain fatty acids: A new anaplerotic anticonvulsant treatment?

(2011) Karin Borges et al.   EPILEPSY RESEARCH

The effects of the ketogenic diet on behavior and cognition

(2011) Tove Hallböök et al.   EPILEPSY RESEARCH

Brain Lactate Metabolism: The Discoveries and the Controversies

(2011) Gerald A Dienel   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The contribution of activated astrocytes to Aβ production: Implications for Alzheimer's disease pathogenesis

(2011) Jie Zhao et al.   Journal of Neuroinflammation

The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics

(2011) Eric Karran et al.   NATURE REVIEWS DRUG DISCOVERY

Pyruvate incubation enhances glycogen stores and sustains neuronal function during subsequent glucose deprivation

(2011) Pavan K. Shetty et al.   NEUROBIOLOGY OF DISEASE

An immunohistochemical finding in glioneuronal lesions associated with epilepsy: The appearance of nestin-positive, CD34-positive and tau-accumulating cells

(2011) Masaya Nagaishi et al.   NEUROPATHOLOGY

Amyloid-β Production: Major Link Between Oxidative Stress and BACE1

(2011) Elena Tamagno et al.   NEUROTOXICITY RESEARCH

Cerebral blood flow and metabolic rate of oxygen, glucose, lactate, pyruvate, ketone bodies and amino acids

(2010) Ulla Lying-Tunell et al.   ACTA NEUROLOGICA SCANDINAVICA

Oligemic Hypoperfusion Differentially Affects Tau and Amyloid-β

(2010) Maya A. Koike et al.   AMERICAN JOURNAL OF PATHOLOGY

Brain Glucose Hypometabolism and Oxidative Stress in Preclinical Alzheimer's Disease

(2010) Lisa Mosconi et al.   Annals of the New York Academy of Sciences

The Revitalized Tau Hypothesis on Alzheimer's Disease

(2010) Ricardo B. Maccioni et al.   ARCHIVES OF MEDICAL RESEARCH

The biochemical basis for the anti-inflammatory and cytoprotective actions of ethyl pyruvate and related compounds

(2010) Kenneth K. Kao et al.   BIOCHEMICAL PHARMACOLOGY

Cortical hypometabolism and hypoperfusion in Parkinson’s disease is extensive: probably even at early disease stages

(2010) Per Borghammer et al.   Brain Structure & Function

The diverse functions of GAPDH: Views from different subcellular compartments

(2010) Carlos Tristan et al.   CELLULAR SIGNALLING

Mitochondrial dysfunction and oxidative stress: a contributing link to acquired epilepsy?

(2010) Simon Waldbaum et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Amyloid-β–induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks

(2010) Jorge J Palop et al.   NATURE NEUROSCIENCE

Brain fuel metabolism, aging, and Alzheimer’s disease

(2010) Stephen Cunnane et al.   NUTRITION

Anticonvulsant and antiepileptic actions of 2-deoxy-D-glucose in epilepsy models

(2009) Carl E. Stafstrom et al.   ANNALS OF NEUROLOGY

Epilepsy and Cognitive Impairments in Alzheimer Disease

(2009) Jorge J. Palop   ARCHIVES OF NEUROLOGY

The effects of a ketogenic diet on ATP concentrations and the number of hippocampal mitochondria in Aldh5a1−/− mice

(2009) Kirk Nylen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Cause and consequence: Mitochondrial dysfunction initiates and propagates neuronal dysfunction, neuronal death and behavioral abnormalities in age-associated neurodegenerative diseases

(2009) Gary E. Gibson et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Mitochondria, oxidative stress, and temporal lobe epilepsy

(2009) Simon Waldbaum et al.   EPILEPSY RESEARCH

Longitudinal microPET imaging of brain glucose metabolism in rat lithium–pilocarpine model of epilepsy

(2009) Karolien Goffin et al.   EXPERIMENTAL NEUROLOGY

Mitochondrial involvement in temporal lobe epilepsy

(2009) Alexei P. Kudin et al.   EXPERIMENTAL NEUROLOGY

The amyloid hypothesis for Alzheimer’s disease: a critical reappraisal

(2009) John Hardy   JOURNAL OF NEUROCHEMISTRY

Dynamic Changes in Presynaptic and Axonal Transport Proteins Combined with Striatal Neuroinflammation Precede Dopaminergic Neuronal Loss in a Rat Model of AAV  -Synucleinopathy

(2009) C. Y. Chung et al.   JOURNAL OF NEUROSCIENCE

Regulation of Glucose Transporter 3 Surface Expression by the AMP-Activated Protein Kinase Mediates Tolerance to Glutamate Excitation in Neurons

(2009) P. Weisova et al.   JOURNAL OF NEUROSCIENCE

Amyloid  -Induced Neuronal Hyperexcitability Triggers Progressive Epilepsy

(2009) R. Minkeviciene et al.   JOURNAL OF NEUROSCIENCE

Neuroinflammation in Parkinson's disease: a target for neuroprotection?

(2009) Etienne C Hirsch et al.   LANCET NEUROLOGY

Neuronal glucose transporter isoform 3 deficient mice demonstrate features of autism spectrum disorders

(2009) Y Zhao et al.   MOLECULAR PSYCHIATRY

Metabolic reconfiguration precedes transcriptional regulation in the antioxidant response

(2009) Markus Ralser et al.   NATURE BIOTECHNOLOGY

Reactive oxygen species are NOXious for neurons

(2009) Nicolas Demaurex et al.   NATURE NEUROSCIENCE

NADPH oxidase is the primary source of superoxide induced by NMDA receptor activation

(2009) Angela M Brennan et al.   NATURE NEUROSCIENCE

In vivo mapping of temporospatial changes in glucose utilization in rat brain during epileptogenesis: an 18F-fluorodeoxyglucose–small animal positron emission tomography study

(2009) Y. Guo et al.   NEUROSCIENCE

Protection of synapses against Alzheimer's-linked toxins: Insulin signaling prevents the pathogenic binding of Aβ oligomers

(2009) Fernanda G. De Felice et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Early involvement of the cerebral cortex in Parkinson's disease: Convergence of multiple metabolic defects

(2009) Isidre Ferrer   PROGRESS IN NEUROBIOLOGY

Synchronous Hyperactivity and Intercellular Calcium Waves in Astrocytes in Alzheimer Mice

(2009) K. V. Kuchibhotla et al.   SCIENCE

Hypometabolism as a therapeutic target in Alzheimer's disease

(2008) Lauren C Costantini et al.   BMC NEUROSCIENCE

The neuroprotective properties of calorie restriction, the ketogenic diet, and ketone bodies

(2008) Marwan Maalouf et al.   BRAIN RESEARCH REVIEWS

Lability of GABAAreceptor function in human partial epilepsy: Possible relationship to hypometabolism

(2008) René Pumain et al.   EPILEPSIA

Neurometabolism in human epilepsy

(2008) Jullie W. Pan et al.   EPILEPSIA

Optimal clinical management of children receiving the ketogenic diet: Recommendations of the International Ketogenic Diet Study Group

(2008) Eric H. Kossoff et al.   EPILEPSIA

The insulin-regulated aminopeptidase IRAP is colocalised with GLUT4 in the mouse hippocampus - potential role in modulation of glucose uptake in neurones?

(2008) Ruani N. Fernando et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Ketogenic diet-fed rats have increased fat mass and phosphoenolpyruvate carboxykinase activity

(2008) Letícia C. Ribeiro et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Endocytosis Is Required for Synaptic Activity-Dependent Release of Amyloid-β In Vivo

(2008) John R. Cirrito et al.   NEURON

Phosphorylation of the Translation Initiation Factor eIF2α Increases BACE1 Levels and Promotes Amyloidogenesis

(2008) Tracy O'Connor et al.   NEURON

Clusters of Hyperactive Neurons Near Amyloid Plaques in a Mouse Model of Alzheimer's Disease

(2008) M. A. Busche et al.   SCIENCE