Risk Factors from Pregnancy to Adulthood in Multiple Sclerosis Outcome

Breastfeeding promotes early neonatal regulatory T cell expansion and immune tolerance of non‐inherited maternal antigens

(2021) HL Wood et al.   ALLERGY

BIRC3 and BIRC5: multi‐faceted inhibitors in cancer

(2021) Raffaele Frazzi   Cell and Bioscience

The Hypothalamic-Pituitary-Adrenal Axis: Development, Programming Actions of Hormones, and Maternal-Fetal Interactions

(2021) Julietta A. Sheng et al.   Frontiers in Behavioral Neuroscience

Associations of serum short-chain fatty acids with circulating immune cells and serum biomarkers in patients with multiple sclerosis

(2021) Stephanie Trend et al.   Scientific Reports

The nature of genetic and environmental susceptibility to multiple sclerosis

(2021) Douglas S. Goodin et al.   PLoS One

Gene-Based Tests of a Genome-Wide Association Study Dataset Highlight Novel Multiple Sclerosis Risk Genes

(2021) He Li et al.   Frontiers in Neuroscience

Air pollution-induced epigenetic changes: disease development and a possible link with hypersensitivity pneumonitis

(2021) Suranjana Mukherjee et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Constipation induced gut microbiota dysbiosis exacerbates experimental autoimmune encephalomyelitis in C57BL/6 mice

(2021) Xiuli Lin et al.   Journal of Translational Medicine

Circulating levels of tight junction proteins in multiple sclerosis: Association with inflammation and disease activity before and after disease modifying therapy

(2021) A. Olsson et al.   Multiple Sclerosis and Related Disorders

Review: The Nutritional Management of Multiple Sclerosis With Propionate

(2021) Derek Tobin et al.   Frontiers in Immunology

Obesity and Multiple Sclerosis—A Multifaceted Association

(2021) Thomas-Gabriel Schreiner et al.   Journal of Clinical Medicine

Comparison of the Intestinal Microbiome of Italian Patients with Multiple Sclerosis and Their Household Relatives

(2021) Paola Galluzzo et al.   Life-Basel

Vitamin D related genetic polymorphisms affect serological response to high-dose vitamin D supplementation in multiple sclerosis

(2021) Max Mimpen et al.   PLoS One

Endocrine disruptors and thyroid autoimmunity

(2020) Salvatore Benvenga et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Epigenetic aspects of multiple sclerosis and future therapeutic options

(2020) Khosro Jamebozorgi et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

Steroids, Pregnancy and Fetal Development

(2020) Maria Emilia Solano et al.   Frontiers in Immunology

Propionic Acid Shapes the Multiple Sclerosis Disease Course by an Immunomodulatory Mechanism

(2020) Alexander Duscha et al.   CELL

Reduced repressive epigenetic marks, increased DNA damage and Alzheimer's disease hallmarks in the brain of humans and mice exposed to particulate urban air pollution

(2020) Lilian Calderón-Garcidueñas et al.   ENVIRONMENTAL RESEARCH

Epigenetic insights into multiple sclerosis disease progression

(2020) L. Kular et al.   JOURNAL OF INTERNAL MEDICINE

Prenatal development of human immunity

(2020) Jong-Eun Park et al.   SCIENCE

B and T Cells Driving Multiple Sclerosis: Identity, Mechanisms and Potential Triggers

(2020) Jamie van Langelaar et al.   Frontiers in Immunology

Genomic and Non-Genomic Mechanisms of Action of Thyroid Hormones and Their Catabolite 3,5-Diiodo-L-Thyronine in Mammals

(2020) Marco Giammanco et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Immature Gut Barrier and Its Importance in Establishing Immunity in Newborn Mammals

(2020) Björn Weström et al.   Frontiers in Immunology

Multiple sclerosis risk variants regulate gene expression in innate and adaptive immune cells

(2020) Melissa M Gresle et al.   Life Science Alliance

HLA-DR15 Molecules Jointly Shape an Autoreactive T Cell Repertoire in Multiple Sclerosis

(2020) Jian Wang et al.   CELL

Gut microbial metabolites as multi-kingdom intermediates

(2020) Kimberly A. Krautkramer et al.   NATURE REVIEWS MICROBIOLOGY

Oxidative Stress Marker Aberrations in Multiple Sclerosis: A Meta-Analysis Study

(2020) Shu-Yao Zhang et al.   Frontiers in Neuroscience

Dysregulation of microRNAs regulating survivin in CD4+ T cells in multiple sclerosis

(2020) Shahin Alizadeh-Fanalou et al.   Multiple Sclerosis and Related Disorders

High birth weight and risk of multiple sclerosis: A multicentre study in Argentina

(2020) Geraldine G. Luetic et al.   Multiple Sclerosis and Related Disorders

Vitamin D/CD46 Crosstalk in Human T Cells in Multiple Sclerosis

(2020) Justin Killick et al.   Frontiers in Immunology

Oxidative Stress Related to Iron Metabolism in Relapsing Remitting Multiple Sclerosis Patients With Low Disability

(2019) Mariacristina Siotto et al.   Frontiers in Neuroscience

Variants in NLRP3 and NLRC4 inflammasome associate with susceptibility and severity of multiple sclerosis

(2019) Jaine LS Soares et al.   Multiple Sclerosis and Related Disorders

Caesarean section and infant formula feeding are associated with an earlier age of onset of multiple sclerosis

(2019) Gloria Dalla Costa et al.   Multiple Sclerosis and Related Disorders

Neuronal vulnerability and multilineage diversity in multiple sclerosis

(2019) Lucas Schirmer et al.   NATURE

New reference intervals for cortisol, cortisol binding globulin and free cortisol index in women using ethinyl estradiol

(2019) Kristine Kollerøs Panton et al.   SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION

A General Introduction to Glucocorticoid Biology

(2019) Steven Timmermans et al.   Frontiers in Immunology

Thyroid Hormone Action on Innate Immunity

(2019) María del Mar Montesinos et al.   Frontiers in Endocrinology

The roles of microRNAs in epigenetic regulation

(2019) Qian Yao et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

microRNAs are potentially regulating the survivin gene in PBMCs from systemic sclerosis patients

(2019) Hamidreza Ebrahimiyan et al.   Modern Rheumatology

Breakdown of Multiple Sclerosis Genetics to Identify an Integrated Disease Network and Potential Variant Mechanisms

(2019) C Joy Shepard et al.   PHYSIOLOGICAL GENOMICS

Ontogenetic expression of thyroid hormone signaling genes: An in vitro and in vivo species comparison

(2019) Kyla M. Walter et al.   PLoS One

Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility

(2019)   SCIENCE

Impairment of Mitochondrial Redox Status in Peripheral Lymphocytes of Multiple Sclerosis Patients

(2019) Hugo Gonzalo et al.   Frontiers in Neuroscience

Hypothyroidism and isolated hypothyroxinemia in pregnancy, from physiology to the clinic

(2019) Eunice López-Muñoz et al.   Taiwanese Journal of Obstetrics & Gynecology

Immunomodulatory Effects of Vitamin D in Pregnancy and Beyond

(2019) Farhan Cyprian et al.   Frontiers in Immunology

Oxidative Stress and Inflammation Interdependence in Multiple Sclerosis

(2019) Rodica Padureanu et al.   Journal of Clinical Medicine

Multiple sclerosis, the microbiome, TLR2, and the hygiene hypothesis

(2019) Nicholas J. Wasko et al.   AUTOIMMUNITY REVIEWS

The FTO gene polymorphism rs9939609 is associated with obesity and disability in multiple sclerosis patients

(2019) Ahmad Al-Serri et al.   Scientific Reports

Environmental risk factors for multiple sclerosis in Japanese people

(2019) Ayako Sakoda et al.   Multiple Sclerosis and Related Disorders

Thyroid disorders in alemtuzumab-treated multiple sclerosis patients: a Belgian consensus on diagnosis and management

(2018) Brigitte Decallonne et al.   ACTA NEUROLOGICA BELGICA

Survivin Monoclonal Antibodies Detect Survivin Cell Surface Expression and Inhibit Tumor GrowthIn Vivo

(2018) Robert A. Fenstermaker et al.   CLINICAL CANCER RESEARCH

Glucocorticoids and CBG during pregnancy in mammals: diversity, pattern, and function

(2018) Phoebe D. Edwards et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Impacts of microbiome metabolites on immune regulation and autoimmunity

(2018) Stefanie Haase et al.   IMMUNOLOGY

Survivin and autoimmunity; the ins and outs

(2018) Hamidreza Ebrahimiyan et al.   IMMUNOLOGY LETTERS

Multiple sclerosis

(2018) Alan J Thompson et al.   LANCET

Association of FTO rs9939609 with Obesity in the Kuwaiti Population: A Public Health Concern?

(2018) Ahmad Al-Serri et al.   MEDICAL PRINCIPLES AND PRACTICE

Reassessing B cell contributions in multiple sclerosis

(2018) Rui Li et al.   NATURE IMMUNOLOGY

Multiple Sclerosis: Mechanisms and Immunotherapy

(2018) Clare Baecher-Allan et al.   NEURON

Role of glucocorticoid negative feedback in the regulation of HPA axis pulsatility

(2018) Julia K Gjerstad et al.   STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS

Effector T Cells in Multiple Sclerosis

(2018) Belinda J. Kaskow et al.   Cold Spring Harbor Perspectives in Medicine

Oxidative Stress: A Major Player in Cerebrovascular Alterations Associated to Neurodegenerative Events

(2018) Cristina Carvalho et al.   Frontiers in Physiology

Gestational Hypothyroxinemia Affects Its Offspring With a Reduced Suppressive Capacity Impairing the Outcome of the Experimental Autoimmune Encephalomyelitis

(2018) Henny Haensgen et al.   Frontiers in Immunology

Genomic Response to Vitamin D Supplementation in the Setting of a Randomized, Placebo-Controlled Trial

(2018) Antonio J. Berlanga-Taylor et al.   EBioMedicine

Effect of Thyroid Hormones on Neurons and Neurodevelopment

(2018) Giovanni Prezioso et al.   Hormone Research in Paediatrics

Bidirectional relationship between eating disorders and autoimmune diseases

(2018) Anna Hedman et al.   JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY

New mitochondrial DNA synthesis enables NLRP3 inflammasome activation

(2018) Zhenyu Zhong et al.   NATURE

You are what you eat: diet, health and the gut microbiota

(2018) Niv Zmora et al.   Nature Reviews Gastroenterology & Hepatology

Multiple sclerosis

(2018) Jiwon Oh et al.   CURRENT OPINION IN NEUROLOGY

Metabolomic Signature in Sera of Multiple Sclerosis Patients during Pregnancy

(2018) Claudia Rossi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The miRNA Expression Profile of Experimental Autoimmune Encephalomyelitis Reveals Novel Potential Disease Biomarkers

(2018) Shivaprasad Venkatesha et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Fat Mass and Obesity Associated (FTO) Gene and Hepatic Glucose and Lipid Metabolism

(2018) Tooru Mizuno   Nutrients

Genome-wide DNA methylation changes in CD19+ B cells from relapsing-remitting multiple sclerosis patients

(2018) Vicki E. Maltby et al.   Scientific Reports

Vitamin D and body mass index in Egyptian multiple sclerosis patients

(2018) Dina Zamzam et al.   Multiple Sclerosis and Related Disorders

The interaction between smoking and HLA genes in multiple sclerosis: replication and refinement

(2017) Anna Karin Hedström et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Combined microRNA and mRNA expression analysis in pediatric multiple sclerosis: an integrated approach to uncover novel pathogenic mechanisms of the disease

(2017) Maria Liguori et al.   HUMAN MOLECULAR GENETICS

Modulating the function of the immune system by thyroid hormones and thyrotropin

(2017) Evelyn L. Jara et al.   IMMUNOLOGY LETTERS

Regulatory T cells in multiple sclerosis and myasthenia gravis

(2017) K. M. Danikowski et al.   Journal of Neuroinflammation

Association of CYP2R1 rs10766197 with MS risk and disease progression

(2017) Concetta Scazzone et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Hypothyroidism

(2017) Layal Chaker et al.   LANCET

Glucocorticoid receptor control of transcription: precision and plasticity via allostery

(2017) Emily R. Weikum et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Breastfeeding, ovulatory years, and risk of multiple sclerosis

(2017) Annette Langer-Gould et al.   NEUROLOGY

Assessing association of comorbidities with treatment choice and persistence in MS

(2017) Alice Laroni et al.   NEUROLOGY

Evidence for a causal relationship between low vitamin D, high BMI, and pediatric-onset MS

(2017) Milena A. Gianfrancesco et al.   NEUROLOGY

25-Hydroxyvitamin D deficiency and risk of MS among women in the Finnish Maternity Cohort

(2017) Kassandra L. Munger et al.   NEUROLOGY

Influence of maternal thyroid hormones during gestation on fetal brain development

(2017) N.K. Moog et al.   NEUROSCIENCE

Ocrelizumab versus Placebo in Primary Progressive Multiple Sclerosis

(2017) Xavier Montalban et al.   NEW ENGLAND JOURNAL OF MEDICINE

Maternal and Perinatal Exposures Are Associated With Risk for Pediatric-Onset Multiple Sclerosis

(2017) Jennifer S. Graves et al.   PEDIATRICS

Eating Disorders, Autoimmune, and Autoinflammatory Disease

(2017) Stephanie Zerwas et al.   PEDIATRICS

Multiple sclerosis - etiology and diagnostic potential

(2017) Joanna Kamińska et al.   Postepy Higieny I Medycyny Doswiadczalnej

Insights in pathogenesis of multiple sclerosis: nitric oxide may induce mitochondrial dysfunction of oligodendrocytes

(2017) Minghong Lan et al.   REVIEWS IN THE NEUROSCIENCES

2017 Guidelines of the American Thyroid Association for the Diagnosis and Management of Thyroid Disease During Pregnancy and the Postpartum

(2017) Erik K. Alexander et al.   THYROID

Pathology of Neurodegenerative Diseases

(2017) Brittany N. Dugger et al.   Cold Spring Harbor Perspectives in Biology

DNA methylation in demyelinated multiple sclerosis hippocampus

(2017) Anthony M. Chomyk et al.   Scientific Reports

Differential methylation at MHC in CD4+ T cells is associated with multiple sclerosis independently of HLA-DRB1

(2017) Vicki E. Maltby et al.   Clinical Epigenetics

Vitamin D receptor gene is epigenetically altered and transcriptionally up-regulated in multiple sclerosis

(2017) Teresa Ayuso et al.   PLoS One

Reactive oxygen species are required for driving efficient and sustained aerobic glycolysis during CD4+ T cell activation

(2017) Dana M. Previte et al.   PLoS One

Smoking induces DNA methylation changes in Multiple Sclerosis patients with exposure-response relationship

(2017) Francesco Marabita et al.   Scientific Reports

Mental Health Comorbidity in MS: Depression, Anxiety, and Bipolar Disorder

(2016) Aaron P. Turner et al.   Current Neurology and Neuroscience Reports

Gestational Hypothyroidism Improves the Ability of the Female Offspring to ClearStreptococcus pneumoniaeInfection and to Recover From Pneumococcal Pneumonia

(2016) Pamela A. Nieto et al.   ENDOCRINOLOGY

Coexistence of eating disorders and autoimmune diseases: Record linkage cohort study, UK

(2016) Clare J. Wotton et al.   INTERNATIONAL JOURNAL OF EATING DISORDERS

Plasma steroid-binding proteins: primary gatekeepers of steroid hormone action

(2016) Geoffrey L Hammond   JOURNAL OF ENDOCRINOLOGY

Regulatory B Cells Induce Formation of IL-10-Expressing T Cells in Mice with Autoimmune Neuroinflammation

(2016) Andrea Pennati et al.   JOURNAL OF NEUROSCIENCE

Multiple Sclerosis and Obesity: Possible Roles of Adipokines

(2016) José de Jesús Guerrero-García et al.   MEDIATORS OF INFLAMMATION

Developmental origins of inflammatory and immune diseases

(2016) Ting Chen et al.   MOLECULAR HUMAN REPRODUCTION

Hispanic Americans and African Americans with multiple sclerosis have more severe disease course than Caucasian Americans

(2016) Rachel E Ventura et al.   Multiple Sclerosis Journal

Neonatal vitamin D status and risk of multiple sclerosis

(2016) Nete Munk Nielsen et al.   NEUROLOGY

Antenatal endogenous and exogenous glucocorticoids and their impact on immune ontogeny and long-term immunity

(2016) María Emilia Solano et al.   Seminars in Immunopathology

Hispanic Americans and African Americans with multiple sclerosis have more severe disease course than Caucasian Americans

(2016) Rachel E Ventura et al.   Multiple Sclerosis Journal

Breg Cells Are Numerically Decreased and Functionally Impaired in Patients With Systemic Sclerosis

(2016) Athanasios Mavropoulos et al.   Arthritis & Rheumatology

Important role of mast cells in multiple sclerosis

(2016) P. Conti et al.   Multiple Sclerosis and Related Disorders

Multiple sclerosis patients have a distinct gut microbiota compared to healthy controls

(2016) Jun Chen et al.   Scientific Reports

Fetal programming and systemic sclerosis

(2015) Gianpaolo Donzelli et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Classification, diagnosis, and differential diagnosis of multiple sclerosis

(2015) Ilana Katz Sand   CURRENT OPINION IN NEUROLOGY

Dietary Fatty Acids Directly Impact Central Nervous System Autoimmunity via the Small Intestine

(2015) Aiden Haghikia et al.   IMMUNITY

Role of the innate and adaptive immune responses in the course of multiple sclerosis

(2015) Bernhard Hemmer et al.   LANCET NEUROLOGY

Maternal Hypothyroxinemia-Induced Neurodevelopmental Impairments in the Progeny

(2015) Hui Min et al.   MOLECULAR NEUROBIOLOGY

Nongenomic actions of thyroid hormone

(2015) Paul J. Davis et al.   Nature Reviews Endocrinology

Evolution of the immune system in humans from infancy to old age

(2015) A. Katharina Simon et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Vitamin D and Risk of Multiple Sclerosis: A Mendelian Randomization Study

(2015) Lauren E. Mokry et al.   PLOS MEDICINE

Genome-wide DNA methylation profiling of CD8+ T cells shows a distinct epigenetic signature to CD4+ T cells in multiple sclerosis patients

(2015) Vicki E. Maltby et al.   Clinical Epigenetics

Involvement of CD8+ T Cells in Multiple Sclerosis

(2015) Marion Salou et al.   Frontiers in Immunology

New regulatory CD19+CD25+ B-cell subset in clinically isolated syndrome and multiple sclerosis relapse. Changes after glucocorticoids

(2014) Clara de Andrés et al.   JOURNAL OF NEUROIMMUNOLOGY

Cervical cord lesion load is associated with disability independently from atrophy in MS

(2014) H. Kearney et al.   NEUROLOGY

Atlas of Multiple Sclerosis 2013: A growing global problem with widespread inequity

(2014) P. Browne et al.   NEUROLOGY

The Increased Risk for Autoimmune Diseases in Patients with Eating Disorders

(2014) Anu Raevuori et al.   PLoS One

Advances in epigenome-wide association studies for common diseases

(2014) Dirk S. Paul et al.   TRENDS IN MOLECULAR MEDICINE

Update on a new controversy in endocrinology: isolated maternal hypothyroxinemia

(2014) R. M. Furnica et al.   JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION

Thyroid Hormones, T3 and T4, in the Brain

(2014) Amy C. Schroeder et al.   Frontiers in Endocrinology

Macrophages in inflammatory multiple sclerosis lesions have an intermediate activation status

(2013) Daphne YS Vogel et al.   Journal of Neuroinflammation

Changes in the Maternal Hypothalamic-Pituitary-Adrenal Axis in Pregnancy and Postpartum: Influences on Maternal and Fetal Outcomes

(2013) Leanne Duthie et al.   NEUROENDOCRINOLOGY

11β-Hydroxysteroid Dehydrogenases: Intracellular Gate-Keepers of Tissue Glucocorticoid Action

(2013) Karen Chapman et al.   PHYSIOLOGICAL REVIEWS

Gestational Hypothyroidism Increases the Severity of Experimental Autoimmune Encephalomyelitis in Adult Offspring

(2013) Eduardo A. Albornoz et al.   THYROID

Myelin-based inhibitors of oligodendrocyte myelination: clues from axonal growth and regeneration

(2013) Feng Mei et al.   Neuroscience Bulletin

The influence of maternal prenatal and early childhood nutrition and maternal prenatal stress on offspring immune system development and neurodevelopmental disorders

(2013) Andrea Horvath Marques et al.   Frontiers in Neuroscience

Experimental gestational hypothyroidism evokes hypertension in adult offspring rats

(2012) Sheyla Oliveira Santos et al.   AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL

The influence of nutritional factors on the prognosis of multiple sclerosis

(2012) Gloria von Geldern et al.   Nature Reviews Neurology

Epigenetic changes in patients with multiple sclerosis

(2012) Marcus W. Koch et al.   Nature Reviews Neurology

The Cellular and Molecular Mechanisms of Immuno-Suppression by Human Type 1 Regulatory T Cells

(2012) Silvia Gregori et al.   Frontiers in Immunology

Pathogenic CD8 T Cells in Multiple Sclerosis and Its Experimental Models

(2012) Eric S. Huseby et al.   Frontiers in Immunology

Gestational vitamin D and the risk of multiple sclerosis in offspring

(2011) Fariba Mirzaei et al.   ANNALS OF NEUROLOGY

Pathology of Demyelinating Diseases

(2011) Bogdan F.Gh. Popescu et al.   Annual Review of Pathology-Mechanisms of Disease

Readers of histone modifications

(2011) Miyong Yun et al.   CELL RESEARCH

Myelin-reactive antibodies mediate the pathology of MBP–PLP fusion protein MP4-induced EAE

(2011) Stefanie Kuerten et al.   CLINICAL IMMUNOLOGY

Hypothyroxinemia and Pregnancy

(2011) Roberto Negro et al.   Endocrine Practice

High density DNA methylation array with single CpG site resolution

(2011) Marina Bibikova et al.   GENOMICS

Changed Histone Acetylation Patterns in Normal-Appearing White Matter and Early Multiple Sclerosis Lesions

(2011) X. Pedre et al.   JOURNAL OF NEUROSCIENCE

Thyroid Hormones as Modulators of Immune Activities at the Cellular Level

(2011) Paolo De Vito et al.   THYROID

Nutrition in multiple sclerosis

(2010) Mario Habek et al.   CLINICAL NEUROLOGY AND NEUROSURGERY

Histone modification levels are predictive for gene expression

(2010) R. Karlic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cross-regulation in development of neuroendocrine and immune systems

(2010) L. A. Zakharova   Russian Journal of Developmental Biology

Helminth infections associated with multiple sclerosis induce regulatory B cells

(2008) Jorge Correale et al.   ANNALS OF NEUROLOGY

Regulatory B cells inhibit EAE initiation in mice while other B cells promote disease progression

(2008) Takashi Matsushita et al.   JOURNAL OF CLINICAL INVESTIGATION