Article
Nutrition & Dietetics
Yung-Chieh Lin, Chen-Yueh Wang, Yu-Wen Pan, Yen-Ju Chen, Wen-Hao Yu, Yen-Yin Chou, Chi-Hsien Huang, Wei-Ying Chu, Chyi-Her Lin, Osuke Iwata
Summary: The study investigated the correlation between low thyroxine levels and long-term neurodevelopmental impairment (NDI) in very preterm infants with normal TSH levels. Despite evaluating the postnatal TT4 concentration at 1 month, the study found that attributing NDI to a single TT4 measurement may require further research for TSH-normal very preterm infants.
Review
Infectious Diseases
Olivier Fortin, Sarah B. Mulkey
Summary: Congenital infections are a major cause of childhood neurodevelopmental disabilities, leading to structural brain abnormalities and impairments such as cerebral palsy, epilepsy, and neurosensory impairments. New congenital infections and global viral pandemics have emerged, affecting the developing brain and causing neurodevelopmental concerns.
CURRENT OPINION IN INFECTIOUS DISEASES
(2023)
Article
Medicine, General & Internal
Bronacha Mylrea-Foley, Jim G. Thornton, Edward Mullins, Neil Marlow, Kurt Hecher, Christina Ammari, Birgit Arabin, Astrid Berger, Eva Bergman, Amarnath Bhide, Caterina Bilardo, Julia Binder, Andrew Breeze, Jana Brodszki, Pavel Calda, Rebecca Cannings-John, Andrej Cerny, Elena Cesari, Irene Cetin, Andrea Dall'Asta, Anke Diemert, Cathrine Ebbing, Torbjorn Eggebo, Ilaria Fantasia, Enrico Ferrazzi, Tiziana Frusca, Tullio Ghi, Jenny Goodier, Patrick Greimel, Wilfried Gyselaers, Wassim Hassan, Constantin Von Kaisenberg, Alexey Kholin, Philipp Klaritsch, Ladislav Krofta, Peter Lindgren, Silvia Lobmaier, Karel Marsal, Giuseppe M. Maruotti, Federico Mecacci, Kirsti Myklestad, Raffaele Napolitano, Eva Ostermayer, Aris Papageorghiou, Claire Potter, Federico Prefumo, Luigi Raio, Jute Richter, Ragnar Kvie Sande, Dietmar Schlembach, Ekkehard Schleussner, Tamara Stampalija, Basky Thilaganathan, Julia Townson, Herbert Valensise, Gerard Ha Visser, Ling Wee, Hans Wolf, Christoph C. Lees
Summary: This study aims to determine the optimal timing of delivery for cases of fetal growth restriction between 32 weeks and 36 weeks 6 days of gestation, based on cerebral blood flow redistribution. The hypothesis is that delivery based on evidence of cerebral blood flow redistribution can reduce poor perinatal outcome, death, and short-term hypoxia-related morbidity, with no worsening of neurodevelopmental outcome at 2 years.
Article
Acoustics
T. Wu, X. Gong, X. Wang, L. Li, Z. Chen, P. Yuan, J. Xie, L. Gong, X. Wang, Y. Zhao, Y. Wei
Summary: This study summarizes the experience of using radiofrequency ablation (RFA) and microwave ablation (MWA) for selective fetal reduction in complicated monochorionic pregnancies and compares the perinatal outcomes of the two techniques. The results demonstrate similar overall survival rates and neurodevelopmental outcomes between RFA and MWA, but MWA is associated with a lower risk of preterm birth.
ULTRASOUND IN OBSTETRICS & GYNECOLOGY
(2022)
Article
Clinical Neurology
Eszter Vojcek, Rozsa Graf, Anna M. Laszlo, Gyula Gyebnar, Istvan Seri
Summary: The study aimed to assess the long-term neurodevelopmental outcome of neonates born at term diagnosed with perinatal haemorrhagic stroke (PHS) and found that the territorial involvement of the stroke and clinical risk factors influenced the outcome of PHS.
DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY
(2022)
Article
Anesthesiology
L. S. Robbins, C. T. Blanchard, F. J. Biasini, M. F. Powell, B. M. Casey, A. T. Tita, L. M. Harper
Summary: General anesthesia during cesarean delivery is not significantly associated with neurodevelopmental delay at two years of age, except for a higher likelihood of severe motor delay in exposed infants. Future studies should further evaluate this association, as well as the impact of longer or multiple anesthesia exposures on neurodevelopment across different gestational ages.
INTERNATIONAL JOURNAL OF OBSTETRIC ANESTHESIA
(2021)
Article
Medicine, General & Internal
Maja Avramovska, Borislav Karanfilski, Goran Dimitrov, Elena Dzikova, Ana Daneva Markova, Marija Hadzi Lega, Gligor Tofoski, Aleksandar Sikole
Summary: This study found that isolated maternal hypothyroxinemia (IMH) was associated with adverse pregnancy outcomes, including lower birth weight, intrauterine growth restriction, lower Apgar scores, and increased likelihood of cesarean section. Additionally, TSH, TT4, and BMI were identified as strong predictors of perinatal outcomes.
ACTA CLINICA CROATICA
(2021)
Article
Medicine, General & Internal
Linghua Kong, Xinxia Chen, Yajun Liang, Yvonne Forsell, Mika Gissler, Catharina Lavebratt
Summary: This study found that simultaneous exposure to maternal preeclampsia and perinatal complications is associated with neurodevelopmental and psychiatric disorders in offspring, including intellectual disabilities, specific developmental disorders, ADHD and conduct disorders, and other behavioral and emotional disorders.
Review
Nutrition & Dietetics
Maud Martinat, Moira Rossitto, Mathieu Di Miceli, Sophie Laye
Summary: The review discusses the accumulation of n-3 and n-6 polyunsaturated fatty acids in the developing brain, including maternal dietary supply, gene polymorphisms related to their metabolism, and gender differences. It also explores the mechanisms linking their bioavailability in the developing brain, their transfer from the mother to the embryo through the placenta, and their role in brain development. Additionally, it examines the potential role of altered bioavailability of long-chain n-3 PUFAs in neurodevelopmental diseases such as autism, attention deficit and hyperactivity disorder, and schizophrenia.
Article
Pediatrics
S. Ares, B. Saenz-Rico, J. Arnaez, J. Diez-Sebastian, F. Omenaca, J. Bernal
Summary: This study aimed to assess the impact of iodine intake on thyroid function and neurodevelopment in preterm infants. The results of a randomized controlled trial showed that infants receiving iodine supplements reached recommended levels in the first days of life.
EUROPEAN JOURNAL OF PEDIATRICS
(2022)
Article
Obstetrics & Gynecology
Michael W. Varner, Elizabeth A. Thom, C. Michael Cotten, Susan R. Hintz, Grier P. Page, Dwight J. Rouse, Brian M. Mercer, Maged M. Costantine, Yoram Sorokin, John M. Thorp Jr, Susan M. Ramin, Marshall W. Carpenter, Mary J. O'Sullivan, Alan M. Peaceman, George R. Saade, Donald J. Dudley, Steve N. Caritis
Summary: This study found genetic variants associated with adverse neurodevelopmental outcomes in extremely low birth weight infants, including a variant in the SERPINE1 gene that is associated with cerebral palsy or death.
AMERICAN JOURNAL OF PERINATOLOGY
(2023)
Article
Pediatrics
Winnie M. Sigal, Ohoud Alzahrani, Gabriela M. Guadalupe, Herodes Guzman, Jerilynn Radcliffe, Nina H. Thomas, Abbas F. Jawad, Diva D. De Leon
Summary: Perinatal stress induced hyperinsulinism (PSIHI) in infants is associated with high risk of neurodevelopmental deficits, with a significant proportion scoring below average on developmental assessments compared to the general population. Risk factors include male sex, being small for gestational age (SGA), and treatment with continuous feeds.
FRONTIERS IN PEDIATRICS
(2022)
Article
Genetics & Heredity
Eline A. Verberne, Shuxiang Goh, Jade England, Manon van Ginkel, Louise Rafael-Croes, Saskia Maas, Abeltje Polstra, Yuri A. Zarate, Katherine A. Bosanko, Kieran B. Pechter, Emma Bedoukian, Kosuke Izumi, Ayeshah Chaudhry, Nathaniel H. Robin, Megan Boothe, Natalie C. Lippa, Vimla Aggarwal, Darryl C. De Vivo, Anna Lehman, Sylvia Stockler, Ange-Line Bruel, Bertrand Isidor, Jennifer Lemons, David F. Rodriguez-Buritica, Christopher M. Richmond, Zornitza Stark, Pankaj B. Agrawal, R. Frank Kooy, Marije E. C. Meuwissen, David A. Koolen, Rolf Pfundt, Agne Lieden, Britt-Marie Anderlid, Dagmar Glatz, Marcel M. A. M. Mannens, Madhura Bakshi, Frederick A. Mallette, Mieke M. van Haelst, Philippe M. Campeau
Summary: This study confirms JARID2 as a human disease gene and further elucidates the associated clinical phenotype. Results from 16 individuals suggest that deletions or variants in JARID2 may lead to developmental delay and/or intellectual disability.
GENETICS IN MEDICINE
(2021)
Article
Clinical Neurology
Alexa X. D. Zhang, Holan Liang, Fiona S. McEwen, Charlotte Tye, Emma Woodhouse, Lisa Underwood, Elizabeth Shephard, Fintan Sheerin, Patrick F. Bolton
Summary: The study found that maternal tuberous sclerosis complex (TSC) is a significant marker of increased perinatal risk. However, after controlling for confounders, there was no significant association between perinatal adversities and neurodevelopmental outcomes.
DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY
(2022)
Article
Genetics & Heredity
Ambrin Fatima, Jan Hoeber, Jens Schuster, Eriko Koshimizu, Carolina Maya-Gonzalez, Boris Keren, Cyril Mignot, Talia Akram, Zafar Ali, Satoko Miyatake, Junpei Tanigawa, Takayoshi Koike, Mitsuhiro Kato, Yoshiko Murakami, Uzma Abdullah, Muhammad Akhtar Ali, Rein Fadoul, Loora Laan, Casimiro Castillejo-Lopez, Maarika Liik, Zhe Jin, Bryndis Birnir, Naomichi Matsumoto, Shahid M. Baig, Joakim Klar, Niklas Dahl
Summary: Neurochondrin (NCDN) is a crucial neural protein involved in neural growth, glutamate receptor signaling, and synaptic plasticity. Variants in NCDN have been associated with developmental delay, intellectual disability, and epilepsy. Studies have shown that NCDN plays a role in neurite formation, synaptic transmission, and normal neuronal biophysical properties.
AMERICAN JOURNAL OF HUMAN GENETICS
(2021)
Article
Endocrinology & Metabolism
J. H. Lazarus, P. N. Taylor
ACTA ENDOCRINOLOGICA-BUCHAREST
(2016)
Article
Nutrition & Dietetics
Elizabeth N. Pearce, John H. Lazarus, Rodrigo Moreno-Reyes, Michael B. Zimmermann
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2016)
Review
Pharmacology & Pharmacy
Onyebuchi E. Okosieme, John H. Lazarus
EXPERT OPINION ON PHARMACOTHERAPY
(2016)
Review
Pharmacology & Pharmacy
I. Khan, O. E. Okosieme, J. H. Lazarus
EXPERT REVIEW OF CLINICAL PHARMACOLOGY
(2017)
Article
Endocrinology & Metabolism
Peter N. Taylor, Adrian Sayers, Onyebuchi Okosieme, Gautam Das, Mohd S. Draman, Arshiya Tabasum, Hussam Abusahmin, Mohammad Rahman, Kirsty Stevenson, Alix Groom, Kate Northstone, Wolf Woltersdorf, Andrew Taylor, Susan Ring, John H. Lazarus, John W. Gregory, Aled Rees, Nicholas Timpson, Colin M. Dayan
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2017)
Article
Genetics & Heredity
P. Perros, L. Hegedus, L. Bartalena, C. Marcocci, G. J. Kahaly, L. Baldeschi, M. Salvi, J. H. Lazarus, A. Eckstein, S. Pitz, K. Boboridis, P. Anagnostis, G. Ayvaz, A. Boschi, T. H. Brix, N. Curro, O. Konuk, M. Marino, A. L. Mitchell, B. Stankovic, F. B. Toruner, G. von Arx, M. Zarkovic, W. M. Wiersinga
ORPHANET JOURNAL OF RARE DISEASES
(2017)
Letter
Endocrinology & Metabolism
John H. Lazarus, Peter P. A. Smyth, Peter N. Taylor, Sandra Weibel, Michael B. Zimmermann
Article
Endocrinology & Metabolism
Erik K. Alexander, Elizabeth N. Pearce, Gregory A. Brent, Rosalind S. Brown, Herbert Chen, Chrysoula Dosiou, William A. Grobman, Peter Laurberg, John H. Lazarus, Susan J. Mandel, Robin P. Peeters, Scott Sullivan
Article
Endocrinology & Metabolism
Charlotte Hales, Peter N. Taylor, Sue Channon, Ruth Paradice, Kirsten McEwan, Lei Zhang, Michael Gyedu, Ameen Bakhsh, Onyebuchi Okosieme, Ilaria Muller, Mohd S. Draman, John W. Gregory, Colin Dayan, John H. Lazarus, D. Aled Rees, Marian Ludgate
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2018)
Review
Endocrinology & Metabolism
Peter N. Taylor, Diana Albrecht, Anna Scholz, Gala Gutierrez-Buey, John H. Lazarus, Colin M. Dayan, Onyebuchi E. Okosieme
NATURE REVIEWS ENDOCRINOLOGY
(2018)
Article
Endocrinology & Metabolism
Henry Voelzke, Iris Erlund, Iris Gruenert, Alicja Hubalewska-Dydejczyk, John H. Lazarus, Robin P. Peeters, Margaret P. Rayman, Uwe Siebert, Betina H. Thuesen, Michael B. Zimmermann
EUROPEAN THYROID JOURNAL
(2018)
Review
Endocrinology & Metabolism
Ishrat Khan, Onyebuchi Okosieme, John Lazarus
EXPERT REVIEW OF ENDOCRINOLOGY & METABOLISM
(2017)
Article
Ophthalmology
F. E. Mellington, C. M. Dayan, A. J. Dickinson, J. L. Hickey, C. J. MacEwen, J. McLaren, P. Perros, G. E. Rose, J. Uddin, B. Vaidya, P. Foley, J. H. Lazarus, A. Mitchell, D. G. Ezra
ORBIT-THE INTERNATIONAL JOURNAL ON ORBITAL DISORDERS-OCULOPLASTIC AND LACRIMAL SURGERY
(2017)
Article
Endocrinology & Metabolism
Raluca M. Furnica, Damien Gruson, John H. Lazarus, Dominique Maiter, Pierre Bernard, Chantal Daumerie
CLINICAL ENDOCRINOLOGY
(2017)
Review
Endocrinology & Metabolism
Henry Voelzke, Iris Erlund, Alicja Hubalewska-Dydejczyk, Till Ittermann, Robin P. Peeters, Margaret Rayman, Monika Buchberger, Uwe Siebert, Betina H. Thuesen, Michael B. Zimmermann, Stefan Gruenert, John H. Lazarus
EUROPEAN THYROID JOURNAL
(2018)
