Breg Cells Are Numerically Decreased and Functionally Impaired in Patients With Systemic Sclerosis

Regulatory B cells are enriched within the IgM memory and transitional subsets in healthy donors but are deficient in chronic GVHD

(2014) A. Khoder et al.   BLOOD

TLR-mediated STAT3 and ERK activation controls IL-10 secretion by human B cells

(2014) Bi-Sheng Liu et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

IL-10 production by B cells is differentially regulated by immune-mediated and infectious stimuli and requires p38 activation

(2014) Francesca Mion et al.   MOLECULAR IMMUNOLOGY

Interleukin-35 induces regulatory B cells that suppress autoimmune disease

(2014) Ren-Xi Wang et al.   NATURE MEDICINE

Altered B cell balance, but unaffected B cell capacity to limit monocyte activation in anti-neutrophil cytoplasmic antibody-associated vasculitis in remission

(2014) N. Lepse et al.   RHEUMATOLOGY

Regulatory B cells are numerically but not functionally deficient in anti-neutrophil cytoplasm antibody-associated vasculitis

(2014) S. K. Todd et al.   RHEUMATOLOGY

Regulatory B cells in ANCA-associated vasculitis

(2013) B Wilde et al.   ANNALS OF THE RHEUMATIC DISEASES

Donor-derived regulatory B cells are important for suppression of murine sclerodermatous chronic graft-versus-host disease

(2013) D. Le Huu et al.   BLOOD

IgG4 production is confined to human IL-10–producing regulatory B cells that suppress antigen-specific immune responses

(2013) Willem van de Veen et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

CD19+CD24hiCD38hi B Cells Maintain Regulatory T Cells While Limiting TH1 and TH17 Differentiation

(2013) F. Flores-Borja et al.   Science Translational Medicine

B lymphocytes and B-cell activating factor promote collagen and profibrotic markers expression by dermal fibroblasts in systemic sclerosis

(2013) Antoine François et al.   ARTHRITIS RESEARCH & THERAPY

IL-10-producing regulatory B cells (B10 cells) in autoimmune disease

(2013) Ioannis Kalampokis et al.   ARTHRITIS RESEARCH & THERAPY

IL-10–Producing Regulatory B10 Cells Ameliorate Collagen-Induced Arthritis via Suppressing Th17 Cell Generation

(2012) Min Yang et al.   AMERICAN JOURNAL OF PATHOLOGY

CD19+CD1d+CD5+ B cell frequencies are increased in patients with tuberculosis and suppress Th17 responses

(2012) Mingxia Zhang et al.   CELLULAR IMMUNOLOGY

B cell depletion therapy ameliorates autoimmune disease through ablation of IL-6–producing B cells

(2012) Tom A. Barr et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Unknown

(2012) Matthew Klinker et al.   MOLECULAR MEDICINE

Regulatory B cells control T-cell autoimmunity through IL-21-dependent cognate interactions

(2012) Ayumi Yoshizaki et al.   NATURE

Decrease in Proportion of CD19+CD24hiCD27+ B Cells and Impairment of Their Suppressive Function in Graves’ Disease

(2012) Bingbing Zha et al.   PLoS One

Human CD19+CD25high B regulatory cells suppress proliferation of CD4+ T cells and enhance Foxp3 and CTLA-4 expression in T-regulatory cells

(2011) Aharon Kessel et al.   AUTOIMMUNITY REVIEWS

Regulatory B cells are identified by expression of TIM-1 and can be induced through TIM-1 ligation to promote tolerance in mice

(2011) Qing Ding et al.   JOURNAL OF CLINICAL INVESTIGATION

Recent insights into the mechanism of action of glatiramer acetate

(2011) Mrinalini Kala et al.   JOURNAL OF NEUROIMMUNOLOGY

IL-10 is Predominantly Produced by CD19(low)CD5(+) Regulatory B Cell Subpopulation: Characterisation of CD19 (high) and CD19(low) Subpopulations of CD5(+) B cells

(2011) Jae Ho Lee et al.   YONSEI MEDICAL JOURNAL

Characterization of a rare IL-10-competent B-cell subset in humans that parallels mouse regulatory B10 cells

(2010) Y. Iwata et al.   BLOOD

CD19+CD24hiCD38hi B Cells Exhibit Regulatory Capacity in Healthy Individuals but Are Functionally Impaired in Systemic Lupus Erythematosus Patients

(2010) Paul A. Blair et al.   IMMUNITY

B cell depletion in diffuse progressive systemic sclerosis: safety, skin score modification and IL-6 modulation in an up to thirty-six months follow-up open-label trial

(2010) Silvia Bosello et al.   ARTHRITIS RESEARCH & THERAPY

B cell depletion with rituximab in patients with diffuse cutaneous systemic sclerosis

(2009) Robert Lafyatis et al.   ARTHRITIS AND RHEUMATISM

Autoantibody-mediated regulation of B cell responses by functional anti-CD22 autoantibodies in patients with systemic sclerosis

(2009) M. Odaka et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

The Development and Function of Regulatory B Cells Expressing IL-10 (B10 Cells) Requires Antigen Receptor Diversity and TLR Signals

(2009) K. Yanaba et al.   JOURNAL OF IMMUNOLOGY

Experience with rituximab in scleroderma: results from a 1-year, proof-of-principle study

(2009) Dimitrios Daoussis et al.   RHEUMATOLOGY

CD19 regulates the development of bleomycin-induced pulmonary fibrosis in a mouse model

(2008) Kazuhiro Komura et al.   ARTHRITIS AND RHEUMATISM

Transitional B cells in humans: Characterization and insight from B lymphocyte reconstitution after hematopoietic stem cell transplantation

(2008) Aude Marie-Cardine et al.   CLINICAL IMMUNOLOGY

Role of the spleen in peripheral memory B-cell homeostasis in patients with autoimmune thrombocytopenia purpura

(2008) Lorena Martinez-Gamboa et al.   CLINICAL IMMUNOLOGY

A Regulatory B Cell Subset with a Unique CD1dhiCD5+ Phenotype Controls T Cell-Dependent Inflammatory Responses

(2008) Koichi Yanaba et al.   IMMUNITY

Regulatory B cells as inhibitors of immune responses and inflammation

(2008) Jean-David Bouaziz et al.   IMMUNOLOGICAL REVIEWS