Vitamin D and Risk of Multiple Sclerosis: A Mendelian Randomization Study

Multiple sclerosis-associated CLEC16A controls HLA class II expression via late endosome biogenesis

(2015) Marvin M. van Luijn et al.   BRAIN

Increased Circulating Levels of Vitamin D Binding Protein in MS Patients

(2015) Arturo Rinaldi et al.   Toxins

Association between circulating 25-hydroxyvitamin D and incident type 2 diabetes: a mendelian randomisation study

(2015) Zheng Ye et al.   Lancet Diabetes & Endocrinology

Vitamin D-binding protein controls T cell responses to vitamin D

(2014) Martin Kongsbak et al.   BMC IMMUNOLOGY

Mendelian randomization: genetic anchors for causal inference in epidemiological studies

(2014) G. Davey Smith et al.   HUMAN MOLECULAR GENETICS

Mendelian randomisation applied to drug development in cardiovascular disease: a review

(2014) Lauren E Mokry et al.   JOURNAL OF MEDICAL GENETICS

Serum lipoprotein composition and vitamin D metabolite levels in clinically isolated syndromes: Results from a multi-center study

(2014) Richard W. Browne et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Summary of evidence-based guideline: Complementary and alternative medicine in multiple sclerosis: Report of the Guideline Development Subcommittee of the American Academy of Neurology

(2014) S. Wright et al.   NEUROLOGY

The Causal Effect of Vitamin D Binding Protein (DBP) Levels on Calcemic and Cardiometabolic Diseases: A Mendelian Randomization Study

(2014) Aaron Leong et al.   PLOS MEDICINE

Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study

(2014) Karani S Vimaleswaran et al.   Lancet Diabetes & Endocrinology

Mendelian Randomization Analysis With Multiple Genetic Variants Using Summarized Data

(2013) Stephen Burgess et al.   GENETIC EPIDEMIOLOGY

Vitamin D-binding Protein in Cerebrospinal Fluid is Associated with Multiple Sclerosis Progression

(2013) Mingchong Yang et al.   MOLECULAR NEUROBIOLOGY

The effect of vitamin D-related interventions on multiple sclerosis relapses: a meta-analysis

(2013) Eleanor James et al.   Multiple Sclerosis Journal

Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis

(2013) Ashley H Beecham et al.   NATURE GENETICS

Discovery and refinement of loci associated with lipid levels

(2013) Cristen J Willer et al.   NATURE GENETICS

Dose-related effects of vitamin D on immune responses in patients with clinically isolated syndrome and healthy control participants: study protocol for an exploratory randomized double- blind placebo-controlled trial

(2013) Karen O’Connell et al.   Trials

Causal Relationship between Obesity and Vitamin D Status: Bi-Directional Mendelian Randomization Analysis of Multiple Cohorts

(2013) Karani S. Vimaleswaran et al.   PLOS MEDICINE

Vitamin D status predicts new brain magnetic resonance imaging activity in multiple sclerosis

(2012) Ellen M. Mowry et al.   ANNALS OF NEUROLOGY

Genetic Regulation of Vitamin D Levels

(2012) Zari Dastani et al.   CALCIFIED TISSUE INTERNATIONAL

Vitamin D-binding protein interacts with Aβ and suppresses Aβ-mediated pathology

(2012) M Moon et al.   CELL DEATH AND DIFFERENTIATION

The Nonskeletal Effects of Vitamin D: An Endocrine Society Scientific Statement

(2012) Clifford J. Rosen et al.   ENDOCRINE REVIEWS

Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study

(2012) Benjamin F Voight et al.   LANCET

An integrated map of genetic variation from 1,092 human genomes

(2012)   NATURE

Evaluation of Genetic Markers as Instruments for Mendelian Randomization Studies on Vitamin D

(2012) Diane J. Berry et al.   PLoS One

Novel Loci for Adiponectin Levels and Their Influence on Type 2 Diabetes and Metabolic Traits: A Multi-Ethnic Meta-Analysis of 45,891 Individuals

(2012) Zari Dastani et al.   PLoS Genetics

Inherited Variation in Vitamin D Genes Is Associated With Predisposition to Autoimmune Disease Type 1 Diabetes

(2011) J. D. Cooper et al.   DIABETES

Latitude is significantly associated with the prevalence of multiple sclerosis: a meta-analysis

(2011) S. Simpson et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

(2011) Georg B. Ehret et al.   NATURE

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

(2011) Stephen Sawcer et al.   NATURE

Epidemiology of Multiple Sclerosis

(2011) Sreeram V. Ramagopalan et al.   NEUROLOGIC CLINICS

A flexible genome-wide bootstrap method that accounts for rankingand threshold-selection bias in GWAS interpretation and replication study design

(2011) Laura L. Faye et al.   STATISTICS IN MEDICINE

Common genetic determinants of vitamin D insufficiency: a genome-wide association study

(2010) Thomas J Wang et al.   LANCET

A phase I/II dose-escalation trial of vitamin D3 and calcium in multiple sclerosis

(2010) J. M. Burton et al.   NEUROLOGY

Expression of the Multiple Sclerosis-Associated MHC Class II Allele HLA-DRB1*1501 Is Regulated by Vitamin D

(2009) Sreeram V. Ramagopalan et al.   PLoS Genetics

Serum 25-hydroxyvitamin D status of the US population: 1988–1994 compared with 2000–2004

(2008) Anne C Looker et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Sensitivity of between-study heterogeneity in meta-analysis: proposed metrics and empirical evaluation

(2008) Nikolaos A Patsopoulos et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Environmental factors and multiple sclerosis

(2008) George C Ebers   LANCET NEUROLOGY

Genetically Elevated C-Reactive Protein and Ischemic Vascular Disease

(2008) Jeppe Zacho et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mendelian randomization: Using genes as instruments for making causal inferences in epidemiology

(2007) Debbie A. Lawlor et al.   STATISTICS IN MEDICINE