Nongenomic actions of thyroid hormone

l-Thyroxine promotes a proliferative airway smooth muscle phenotype in the presence of TGF-β1

(2015) Bart G. J. Dekkers et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Overlapping nongenomic and genomic actions of thyroid hormone and steroids

(2015) Stephen R. Hammes et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Thyroid hormones and tetrac: new regulators of tumour stroma formation via integrin αvβ3

(2015) Kathrin A Schmohl et al.   ENDOCRINE-RELATED CANCER

3,5-Diiodo-L-Thyronine (3,5-T2) Exerts Thyromimetic Effects on Hypothalamus-Pituitary-Thyroid Axis, Body Composition, and Energy Metabolism in Male Diet-Induced Obese Mice

(2015) Wenke Jonas et al.   ENDOCRINOLOGY

Prothrombotic changes due to an increase in thyroid hormone levels

(2015) J. Horacek et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Insights into Enzyme Catalysis and Thyroid Hormone Regulation of Cerebral Ketimine Reductase/μ-Crystallin Under Physiological Conditions

(2015) André Hallen et al.   NEUROCHEMICAL RESEARCH

Thyroid hormone and anti-apoptosis in tumor cells

(2015) Hung-Yun Lin et al.   Oncotarget

3,5-Diiodo-L-Thyronine Activates Brown Adipose Tissue Thermogenesis in Hypothyroid Rats

(2015) Assunta Lombardi et al.   PLoS One

Thyroid hormone regulates adhesion, migration and matrix metalloproteinase 9 activity via αvβ3 integrin in myeloma cells

(2015) Keren Cohen et al.   Oncotarget

Modulation of angiogenesis by thyroid hormone and hormone analogues: implications for cancer management

(2014) Shaker A. Mousa et al.   ANGIOGENESIS

Integrin  v 3 acting as membrane receptor for thyroid hormones mediates angiogenesis in malignant T cells

(2014) F. Cayrol et al.   BLOOD

Integrin  v 3 and thyroid hormones promote expansion of progenitors in embryonic neocortex

(2014) D. Stenzel et al.   DEVELOPMENT

Cytosolic T3-binding protein modulates dynamic alteration of T3-mediated gene expression in cells

(2014) Keiko Takeshige et al.   ENDOCRINE JOURNAL

Thyroid Hormone, Thyromimetics, and Metabolic Efficiency

(2014) Einav Yehuda-Shnaidman et al.   ENDOCRINE REVIEWS

A Rapid Cytoplasmic Mechanism for PI3 Kinase Regulation by the Nuclear Thyroid Hormone Receptor, TRβ, and Genetic Evidence for Its Role in the Maturation of Mouse Hippocampal Synapses In Vivo

(2014) Negin P. Martin et al.   ENDOCRINOLOGY

Triiodothyronine Prevents Cardiac Ischemia/Reperfusion Mitochondrial Impairment and Cell Loss by Regulating miR30a/p53 Axis

(2014) Francesca Forini et al.   ENDOCRINOLOGY

p28, a truncated form of TRα1 regulates mitochondrial physiology

(2014) Laurence Pessemesse et al.   FEBS LETTERS

Administration of 3,5‐diiodothyronine (3,5‐T2) causes central hypothyroidism and stimulates thyroid‐sensitive tissues

(2014) Alvaro Souto Padron et al.   JOURNAL OF ENDOCRINOLOGY

Thyroid hormone induced angiogenesis through the integrin αvβ3/protein kinase D/histone deacetylase 5 signaling pathway

(2014) Xin Liu et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Relevance of the thyroid hormones–αvβ3 pathway in primary myeloma bone marrow cells and to bortezomib action

(2014) Keren Cohen et al.   LEUKEMIA & LYMPHOMA

Nongenomic Thyroid Hormone Signaling Occurs Through a Plasma Membrane-Localized Receptor

(2014) H. Kalyanaraman et al.   Science Signaling

Recurrence of Differentiated Thyroid Carcinoma During Full TSH Suppression: Is the Tumor Now Thyroid Hormone Dependent?

(2014) Paul J. Davis et al.   Hormones & Cancer

3,5-Diiodo-l-thyronine ameliorates diabetic nephropathy in streptozotocin-induced diabetic rats

(2013) Guoguo Shang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Thyroid hormones differentially regulate phosphorylation of ERK and Akt via integrinαvβ3 receptor in undifferentiated and differentiated PC-12 cells

(2013) Tamar Barbakadze et al.   CELL BIOCHEMISTRY AND FUNCTION

Signaling networks of Rho GTPases in cell motility

(2013) Samer Hanna et al.   CELLULAR SIGNALLING

Nuclear monomeric integrin αv in cancer cells is a coactivator regulated by thyroid hormone

(2013) Hung-Yun Lin et al.   FASEB JOURNAL

FoxO1 Deacetylation Regulates Thyroid Hormone-induced Transcription of Key Hepatic Gluconeogenic Genes

(2013) Brijesh Kumar Singh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

3,5-di-iodothyronine stimulates tilapia growth through an alternate isoform of thyroid hormone receptor β1

(2013) Pamela Navarrete-Ramírez et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Thyroid hormones and mitochondria: With a brief look at derivatives and analogues

(2013) Federica Cioffi et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Tetraiodothyroacetic acid-conjugated PLGA nanoparticles: a nanomedicine approach to treat drug-resistant breast cancer

(2013) Dhruba J Bharali et al.   Nanomedicine

Mice Lacking the p43 Mitochondrial T3 Receptor Become Glucose Intolerant and Insulin Resistant during Aging

(2013) Christelle Bertrand et al.   PLoS One

Inherited defects of thyroid hormone-cell-membrane transport

(2013) Jiao Fu et al.   Current Opinion in Endocrinology Diabetes and Obesity

Response of Human Pancreatic Cancer Cell Xenografts to Tetraiodothyroacetic Acid Nanoparticles

(2013) Murat Yalcin et al.   Hormones & Cancer

Integrin participates in the effect of thyroxine on plasma membrane in immature rat testis

(2012) Ana Paula Zanatta et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Thyroid Hormone Reduces Cholesterol via a Non-LDL Receptor-Mediated Pathway

(2012) Ira J. Goldberg et al.   ENDOCRINOLOGY

Thyroid hormone is highly permissive in angioproliferative pulmonary hypertension in rats

(2012) A. Al Husseini et al.   EUROPEAN RESPIRATORY JOURNAL

Combined QM/MM Study of Thyroid and Steroid Hormone Analogue Interactions with Integrin

(2012) Marek Freindorf et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Molecular components underlying nongenomic thyroid hormone signaling in embryonic zebrafish neurons

(2012) Marc A Yonkers et al.   Neural Development

Thyroid Hormone Enhances Nitric Oxide-Mediated Bacterial Clearance and Promotes Survival after Meningococcal Infection

(2012) Yao Chen et al.   PLoS One

Severe Pulmonary Hypertension: The Role of Metabolic and Endocrine Disorders

(2012) Harm J. Bogaard et al.   Pulmonary Circulation

Membrane Receptor for Thyroid Hormone: Physiologic and Pharmacologic Implications

(2011) Paul J. Davis et al.   Annual Review of Pharmacology and Toxicology

The pro-apoptotic action of stilbene-induced COX-2 in cancer cells: Convergence with the anti-apoptotic effect of thyroid hormone

(2011) Hung-Yun Lin et al.   CELL CYCLE

Modification of survival pathway gene expression in human breast cancer cells by tetraiodothyroacetic acid (tetrac)

(2011) Anna B. Glinskii et al.   CELL CYCLE

Nonthyrotoxic Prevention of Diet-Induced Insulin Resistance by 3,5-Diiodo-L-Thyronine in Rats

(2011) Pieter de Lange et al.   DIABETES

Inhibition of pathological retinal angiogenesis by the integrin αvβ3 antagonist tetraiodothyroacetic acid (tetrac)

(2011) Takeshi Yoshida et al.   EXPERIMENTAL EYE RESEARCH

3,5-Diiodo-l-thyronine prevents high-fat-diet-induced insulin resistance in rat skeletal muscle through metabolic and structural adaptations

(2011) Maria Moreno et al.   FASEB JOURNAL

3,5,3′triiodo-L-thyronine induces SREBP-1 expression by non-genomic actions in human HEP G2 cells

(2011) Gabriele V. Gnoni et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Non-receptor-mediated actions are responsible for the lipid-lowering effects of iodothyronines in FaO rat hepatoma cells

(2011) Elena Grasselli et al.   JOURNAL OF ENDOCRINOLOGY

Tetraiodothyroacetic acid and its nanoformulation inhibit thyroid hormone stimulation of non-small cell lung cancer cells in vitro and its growth in xenografts

(2011) Shaker A. Mousa et al.   LUNG CANCER

Coordination of mitochondrial biogenesis by thyroid hormone

(2011) Joachim M. Weitzel et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Differential Recruitment of Nuclear Coregulators Directs the Isoform-Dependent Action of Mutant Thyroid Hormone Receptors

(2011) Laura Fozzatti et al.   MOLECULAR ENDOCRINOLOGY

Crosstalk between Integrin αvβ3 and Estrogen Receptor-α Is Involved in Thyroid Hormone-Induced Proliferation in Human Lung Carcinoma Cells

(2011) Ran Meng et al.   PLoS One

Pharmacodynamic Modeling of Anti-Cancer Activity of Tetraiodothyroacetic Acid in a Perfused Cell Culture System

(2011) Hung-Yun Lin et al.   PLoS Computational Biology

Atomic Force Microscopy-Based Molecular Recognition of a Fibrinogen Receptor on Human Erythrocytes

(2010) Filomena A. Carvalho et al.   ACS Nano

Molecular Aspects of Thyroid Hormone Actions

(2010) Sheue-Yann Cheng et al.   ENDOCRINE REVIEWS

Tetraiodothyroacetic Acid (Tetrac) and Nanoparticulate Tetrac Arrest Growth of Medullary Carcinoma of the Thyroid

(2010) M. Yalcin et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Thyroid hormones induce activation of rat hepatic stellate cells through increased expression of p75 neurotrophin receptor and direct activation of Rho

(2010) Isabel Zvibel et al.   LABORATORY INVESTIGATION

Minireview: Thyroid Hormone Transporters: The Knowns and the Unknowns

(2010) W. Edward Visser et al.   MOLECULAR ENDOCRINOLOGY

Tetraiodothyroacetic Acid and Tetraiodothyroacetic Acid Nanoparticle Effectively Inhibit the Growth of Human Follicular Thyroid Cell Carcinoma

(2010) Murat Yalcin et al.   THYROID

l-Thyroxine vs. 3,5,3′-triiodo-l-thyronine and cell proliferation: activation of mitogen-activated protein kinase and phosphatidylinositol 3-kinase

(2009) Hung-Yun Lin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Human Platelet Aggregation and Degranulation Is Induced In Vitro by L-Thyroxine, but Not by 3,5,3′-Triiodo-L-Thyronine or Diiodothyropropionic Acid (DITPA)

(2009) Shaymaa S. Mousa et al.   CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS

Cytoplasm-To-Nucleus Shuttling Of Thyroid Hormone Receptor-β1 (Trβ1) Is Directed From A Plasma Membrane Integrin Receptor By Thyroid Hormone

(2009) H. James Cao et al.   ENDOCRINE RESEARCH

Thyroid hormone action during brain development: More questions than answers

(2009) Sigrun Horn et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Thyroid hormone and angiogenesis

(2009) Mary K. Luidens et al.   VASCULAR PHARMACOLOGY

Cell-specific signal transduction pathways regulating Na+-K+-ATPase. Focus on “Short-term effects of thyroid hormones on the Na+-K+-ATPase activity of chick embryo hepatocytes during development: focus on signal transduction”

(2008) Jianxun Lei et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

T3 increases Na-K-ATPase activity via a MAPK/ERK1/2-dependent pathway in rat adult alveolar epithelial cells

(2008) Jianxun Lei et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Activation of Phosphatidylinositol 3-Kinase Signaling Promotes Aberrant Pituitary Growth in a Mouse Model of Thyroid-Stimulating Hormone-Secreting Pituitary Tumors

(2008) Changxue Lu et al.   ENDOCRINOLOGY

Modulation of erythroid adhesion receptor expression by hydroxyurea in children with sickle cell disease

(2008) M.-H. Odievre et al.   HAEMATOLOGICA

Thyroid hormone stimulation of extracellular signal-regulated kinase and cell proliferation in human osteoblast-like cells is initiated at integrin αVβ3

(2008) A Scarlett et al.   JOURNAL OF ENDOCRINOLOGY

Sensory Neuron Sodium Current Requires Nongenomic Actions of Thyroid Hormone During Development

(2008) Marc A. Yonkers et al.   JOURNAL OF NEUROPHYSIOLOGY