Exploring links between 2‐oxoglutarate‐dependent oxygenases and Alzheimer's disease
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Title
Exploring links between 2‐oxoglutarate‐dependent oxygenases and Alzheimer's disease
Authors
Keywords
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Journal
Alzheimers & Dementia
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2022-07-19
DOI
10.1002/alz.12733
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Note: Only part of the references are listed.- Single cell sequencing coupled with bioinformatics reveals PHYH as a potential biomarker in kidney ischemia reperfusion injury
- (2022) Ruiquan Xu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Iron Dyshomeostasis and Ferroptosis: A New Alzheimer’s Disease Hypothesis?
- (2022) Feixue Wang et al. Frontiers in Aging Neuroscience
- Regional brain iron associated with deterioration in Alzheimer's disease: A large cohort study and theoretical significance
- (2021) Scott Ayton et al. Alzheimers & Dementia
- The histone demethylase KDM5 is required for synaptic structure and function at the Drosophila neuromuscular junction
- (2021) Helen M. Belalcazar et al. Cell Reports
- Human Oxygenase Variants Employing a Single Protein Fe II Ligand Are Catalytically Active
- (2021) Amelia Brasnett et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- VEGF counteracts amyloid-β-induced synaptic dysfunction
- (2021) Laurent Martin et al. Cell Reports
- A KDM5–Prospero transcriptional axis functions during early neurodevelopment to regulate mushroom body formation
- (2021) Hayden AM Hatch et al. eLife
- The Role of 2-Oxoglutarate Dependent Dioxygenases in Gliomas and Glioblastomas: A Review of Epigenetic Reprogramming and Hypoxic Response
- (2021) Rebekah L. I. Crake et al. Frontiers in Oncology
- Hypoxia and brain aging: Neurodegeneration or neuroprotection?
- (2021) Johannes Burtscher et al. AGEING RESEARCH REVIEWS
- The histone demethylase PHF8 regulates astrocyte differentiation and function
- (2021) Simona Iacobucci et al. DEVELOPMENT
- Molecular and cellular events linking variants in the histone demethylase KDM5C to the intellectual disability disorder Claes‐Jensen syndrome
- (2021) Hayden A. M. Hatch et al. FEBS Journal
- Erythropoietin and derivatives: Potential beneficial effects on the brain
- (2021) Daniela C. Vittori et al. JOURNAL OF NEUROCHEMISTRY
- Clinical trial of neuroEPO in mild‐to‐moderate Alzheimer’s disease
- (2021) Leslie Pérez et al. Alzheimers & Dementia
- Kinetic parameters of human aspartate/asparagine-β-hydroxylase suggest that it has a possible function in oxygen sensing
- (2020) Lennart Brewitz et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inhibition of Endothelial PHD2 Suppresses Post-Ischemic Kidney Inflammation through Hypoxia-Inducible Factor-1
- (2020) Ganeshkumar Rajendran et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Abnormality of m6A mRNA Methylation Is Involved in Alzheimer’s Disease
- (2020) Min Han et al. Frontiers in Neuroscience
- Iron dyshomeostasis, lipid peroxidation and perturbed expression of cystine/glutamate antiporter in Alzheimer’s disease: Evidence of ferroptosis
- (2020) Azhaar Ashraf et al. Redox Biology
- In vivo measurement of widespread synaptic loss in Alzheimer's disease with SV2A PET
- (2020) Adam P. Mecca et al. Alzheimers & Dementia
- Understanding the Oxygen Sensing Pathway and Its Therapeutic Implications in Diseases
- (2020) Chengheng Liao et al. AMERICAN JOURNAL OF PATHOLOGY
- Extracellular matrix proteins involved in Alzheimer’s disease
- (2020) Jun Ma et al. CHEMISTRY-A EUROPEAN JOURNAL
- Hypoxia and hypoxia mimetics differentially modulate histone post-translational modifications
- (2020) Kuo-Feng Hsu et al. Epigenetics
- Selective loss of 5hmC promotes neurodegeneration in the mouse model of Alzheimer's disease
- (2020) Ying Zhang et al. FASEB JOURNAL
- Ascorbate deficiency decreases dopamine release in gulo –/– and APP/PSEN1 mice
- (2020) David C. Consoli et al. JOURNAL OF NEUROCHEMISTRY
- Epigenetic regulators of neuronal ferroptosis identify novel therapeutics for neurological diseases: HDACs, transglutaminases, and HIF prolyl hydroxylases
- (2020) Orjon Rroji et al. NEUROBIOLOGY OF DISEASE
- Hypoxia induces rapid changes to histone methylation and reprograms chromatin
- (2019) Michael Batie et al. SCIENCE
- Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
- (2019) Abhishek A. Chakraborty et al. SCIENCE
- Nuclear factor‐kappa β as a therapeutic target for Alzheimer's disease
- (2019) Niraj Kumar Jha et al. JOURNAL OF NEUROCHEMISTRY
- JAK2/STAT3 signaling mediates IL-6-inhibited neurogenesis of neural stem cells through DNA demethylation/methylation
- (2019) Xuejian Kong et al. BRAIN BEHAVIOR AND IMMUNITY
- Inhibition of EHMT1/2 rescues synaptic and cognitive functions for Alzheimer’s disease
- (2019) Yan Zheng et al. BRAIN
- The small members of the JMJD protein family: Enzymatic jewels or jinxes?
- (2019) Sangphil Oh et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Tau protein aggregates inhibit the protein-folding and vesicular trafficking arms of the cellular proteostasis network
- (2019) Anan Yu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Polycomb Repressive 2 Complex—Molecular Mechanisms of Function
- (2019) Valentina L Kouznetsova et al. PROTEIN SCIENCE
- Genetic and Real-World Clinical Data, Combined with Empirical Validation, Nominate Jak-Stat Signaling as a Target for Alzheimer’s Disease Therapeutic Development
- (2019) Nevado-Holgado et al. Cells
- Metal Ions in Alzheimer’s Disease: A Key Role or Not?
- (2019) Yan Liu et al. ACCOUNTS OF CHEMICAL RESEARCH
- Synaptic Elimination in Neurological Disorders
- (2019) Fabíola M. Ribeiro et al. Current Neuropharmacology
- Vascular Cognitive Impairment and Dementia
- (2019) Costantino Iadecola et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- TET enzymes in neurophysiology and brain function
- (2019) Cláudia Antunes et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- Hypoxia-Inducible Factor Activators in Renal Anemia: Current Clinical Experience
- (2019) Neil S. Sanghani et al. ADVANCES IN CHRONIC KIDNEY DISEASE
- DRG2 knockdown induces Golgi fragmentation via GSK3β phosphorylation and microtubule stabilization
- (2019) Muralidharan Mani et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Long Non-coding RNA MALAT1 Inhibits Neuron Apoptosis and Neuroinflammation While Stimulates Neurite Outgrowth and Its Correlation With MiR-125b Mediates PTGS2, CDK5 and FOXQ1 in Alzheimer's Disease
- (2019) Peizhi Ma et al. Current Alzheimer Research
- Association between alcohol consumption and Alzheimer's disease: A Mendelian randomization study
- (2019) Shea J. Andrews et al. Alzheimers & Dementia
- The neural stem cell/carnitine malnutrition hypothesis: new prospects for effective reduction of autism risk?
- (2019) Vytas A. Bankaitis et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- FTO: An Emerging Molecular Player in Neuropsychiatric Diseases
- (2019) P.K. Annapoorna et al. NEUROSCIENCE
- TET2 Regulates the Neuroinflammatory Response in Microglia
- (2019) Alejandro Carrillo-Jimenez et al. Cell Reports
- Reduction of Tet2 exacerbates early stage Alzheimer’s pathology and cognitive impairments in 2 × Tg-ad mice
- (2019) Liping Li et al. HUMAN MOLECULAR GENETICS
- Ethnicity-specific and overlapping alterations of brain hydroxymethylome in Alzheimer’s disease
- (2019) Lixia Qin et al. HUMAN MOLECULAR GENETICS
- Aluminium-induced synaptic plasticity injury via the PHF8–H3K9me2-BDNF signalling pathway
- (2019) Huan Li et al. CHEMOSPHERE
- A systematic integrated analysis of brain expression profiles reveals YAP1 and other prioritized hub genes as important upstream regulators in Alzheimer's disease
- (2018) Min Xu et al. Alzheimers & Dementia
- FTO is involved in Alzheimer's disease by targeting TSC1-mTOR-Tau signaling
- (2018) Huajie Li et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- LncRNA-MALAT1 promotes CPC proliferation and migration in hypoxia by up-regulation of JMJD6 via sponging miR-125
- (2018) Linlin Li et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Mitochondria and Hypoxia: Metabolic Crosstalk in Cell-Fate Decisions
- (2018) David Bargiela et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- MicroRNA-455-3p as a Potential Biomarker for Alzheimer's Disease: An Update
- (2018) Subodh Kumar et al. Frontiers in Aging Neuroscience
- UTX Affects Neural Stem Cell Proliferation and Differentiation through PTEN Signaling
- (2018) Xuepei Lei et al. Stem Cell Reports
- Striking while the iron is hot: Iron metabolism and Ferroptosis in neurodegeneration
- (2018) Shashank Masaldan et al. FREE RADICAL BIOLOGY AND MEDICINE
- Microglia in Alzheimer’s disease
- (2017) Heela Sarlus et al. JOURNAL OF CLINICAL INVESTIGATION
- Hypoxia/ischemia activate processing of Amyloid Precursor Protein: impact of vascular dysfunction in the pathogenesis of Alzheimer's disease
- (2017) Antero Salminen et al. JOURNAL OF NEUROCHEMISTRY
- Clipping of arginine-methylated histone tails by JMJD5 and JMJD7
- (2017) Haolin Liu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Small things matter: Implications of APP intracellular domain AICD nuclear signaling in the progression and pathogenesis of Alzheimer’s disease
- (2017) Hassan Bukhari et al. PROGRESS IN NEUROBIOLOGY
- Molecular and cellular mechanisms of HIF prolyl hydroxylase inhibitors in clinical trials
- (2017) Tzu-Lan Yeh et al. Chemical Science
- Acute and Chronic Sustained Hypoxia Do Not Substantially Regulate Amyloid-β Peptide Generation In Vivo
- (2017) Alberto Serrano-Pozo et al. PLoS One
- JMJD8 Regulates Angiogenic Sprouting and Cellular Metabolism by Interacting With Pyruvate Kinase M2 in Endothelial CellsHighlights
- (2016) Jes-Niels Boeckel et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Phyhd1, an XPhyH-like homologue, is induced in mouse T cells upon T cell stimulation
- (2016) Yuri Furusawa et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Prolyl-4-hydroxylase 2 and 3 coregulate murine erythropoietin in brain pericytes
- (2016) Andres A. Urrutia et al. BLOOD
- ALKBH1-Mediated tRNA Demethylation Regulates Translation
- (2016) Fange Liu et al. CELL
- Adult Neurogenesis in the Hippocampus: From Stem Cells to Behavior
- (2016) J. Tiago Gonçalves et al. CELL
- NSUN3 and ABH1 modify the wobble position of mt‐tRNAMetto expand codon recognition in mitochondrial translation
- (2016) Sara Haag et al. EMBO JOURNAL
- Neuronal prolyl-4-hydroxylase 2 deficiency improves cognitive abilities in a murine model of cerebral hypoperfusion
- (2016) Daniel Gruneberg et al. EXPERIMENTAL NEUROLOGY
- Role of TET enzymes in DNA methylation, development, and cancer
- (2016) Kasper Dindler Rasmussen et al. GENES & DEVELOPMENT
- Tuning the Transcriptional Response to Hypoxia by Inhibiting Hypoxia-inducible Factor (HIF) Prolyl and Asparaginyl Hydroxylases
- (2016) Mun Chiang Chan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Arginine demethylation is catalysed by a subset of JmjC histone lysine demethylases
- (2016) Louise J. Walport et al. Nature Communications
- Hypoxia-Inducible Histone Lysine Demethylases: Impact on the Aging Process and Age-Related Diseases
- (2016) Salminen Antero et al. Aging and Disease
- JMJD8 is a positive regulator of TNF-induced NF-κB signaling
- (2016) Kok Siong Yeo et al. Scientific Reports
- Noncanonical regulation of alkylation damage resistance by the OTUD4 deubiquitinase
- (2015) Y. Zhao et al. EMBO JOURNAL
- JMJD3 as an epigenetic regulator in development and disease
- (2015) Jana S. Burchfield et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Epigenetics of Aging and Alzheimer’s Disease: Implications for Pharmacogenomics and Drug Response
- (2015) Ramón Cacabelos et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Protein Hydroxylation Catalyzed by 2-Oxoglutarate-dependent Oxygenases
- (2015) Suzana Markolovic et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The AlkB Family of Fe(II)/α-Ketoglutarate-dependent Dioxygenases: Repairing Nucleic Acid Alkylation Damage and Beyond
- (2015) Bogdan I. Fedeles et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Multi-target iron-chelators improve memory loss in a rat model of sporadic Alzheimer's disease
- (2015) Melita Salkovic-Petrisic et al. LIFE SCIENCES
- Tet2 is required to resolve inflammation by recruiting Hdac2 to specifically repress IL-6
- (2015) Qian Zhang et al. NATURE
- Aberrant intracellular localization of H3k4me3 demonstrates an early epigenetic phenomenon in Alzheimer's disease
- (2015) Diego Mastroeni et al. NEUROBIOLOGY OF AGING
- Impaired mitochondrial energy metabolism in Alzheimer's disease: Impact on pathogenesis via disturbed epigenetic regulation of chromatin landscape
- (2015) Antero Salminen et al. PROGRESS IN NEUROBIOLOGY
- Aspartate-β-hydroxylase induces epitope-specific T cell responses in hepatocellular carcinoma
- (2015) Yoshito Tomimaru et al. VACCINE
- Genes associated with the progression of neurofibrillary tangles in Alzheimer’s disease
- (2015) A Miyashita et al. Translational Psychiatry
- Genetic modification of the relationship between phosphorylated tau and neurodegeneration
- (2014) Timothy J. Hohman et al. Alzheimers & Dementia
- Therapeutic potential of intermittent hypoxia: a matter of dose
- (2014) Angela Navarrete-Opazo et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- Role of the N6-methyladenosine RNA mark in gene regulation and its implications on development and disease
- (2014) U. Chandola et al. Briefings in Functional Genomics
- Neurogenesis in the Striatum of the Adult Human Brain
- (2014) Aurélie Ernst et al. CELL
- Early miR-155 upregulation contributes to neuroinflammation in Alzheimer's disease triple transgenic mouse model
- (2014) Joana R. Guedes et al. HUMAN MOLECULAR GENETICS
- miR-155 Activates Cytokine Gene Expression in Th17 Cells by Regulating the DNA-Binding Protein Jarid2 to Relieve Polycomb-Mediated Repression
- (2014) Thelma M. Escobar et al. IMMUNITY
- The Atomic Resolution Structure of Human AlkB Homolog 7 (ALKBH7), a Key Protein for Programmed Necrosis and Fat Metabolism
- (2014) Guoqiang Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structures of Human ALKBH5 Demethylase Reveal a Unique Binding Mode for Specific Single-strandedN6-Methyladenosine RNA Demethylation
- (2014) Chao Xu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Crystal Structures of the Human RNA Demethylase Alkbh5 Reveal Basis for Substrate Recognition
- (2014) Chong Feng et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Coordinated Regulation of Retinoic Acid Signaling Pathway by KDM5B and Polycomb Repressive Complex 2
- (2014) Yu Zhang et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Homology modeling, molecular dynamics, and site-directed mutagenesis study of AlkB human homolog 1 (ALKBH1)
- (2014) Pavel Silvestrov et al. JOURNAL OF MOLECULAR GRAPHICS & MODELLING
- Optimal Translational Termination Requires C4 Lysyl Hydroxylation of eRF1
- (2014) Tianshu Feng et al. MOLECULAR CELL
- Tau promotes neurodegeneration through global chromatin relaxation
- (2014) Bess Frost et al. NATURE NEUROSCIENCE
- The dynamic epitranscriptome: N6-methyladenosine and gene expression control
- (2014) Kate D. Meyer et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Inhibition of HIF prolyl-4-hydroxylases by FG-4497 Reduces Brain Tissue Injury and Edema Formation during Ischemic Stroke
- (2014) Stefan Reischl et al. PLoS One
- JMJD6 Regulates ERα Methylation on Arginine
- (2014) Coralie Poulard et al. PLoS One
- OGFOD1 catalyzes prolyl hydroxylation of RPS23 and is involved in translation control and stress granule formation
- (2014) R. S. Singleton et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The roles of Jumonji-type oxygenases in human disease
- (2014) Catrine Johansson et al. Epigenomics
- Nontranscriptional Role of Hif-1α in Activation of γ-Secretase and Notch Signaling in Breast Cancer
- (2014) Jennifer C. Villa et al. Cell Reports
- Activation of Neuronal Gene Expression by the JMJD3 Demethylase Is Required for Postnatal and Adult Brain Neurogenesis
- (2014) Dae Hwi Park et al. Cell Reports
- Epigenetic studies in Alzheimer's disease: Current findings, caveats, and considerations for future studies
- (2013) Katie Lunnon et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS
- A covalent protein–DNA 5′-product adduct is generated following AP lyase activity of human ALKBH1 (AlkB homologue 1)
- (2013) Tina A. Müller et al. BIOCHEMICAL JOURNAL
- Structural insights into how 5-hydroxymethylation influences transcription factor binding
- (2013) Lukas Lercher et al. CHEMICAL COMMUNICATIONS
- Human ALKBH7 is required for alkylation and oxidation-induced programmed necrosis
- (2013) D. Fu et al. GENES & DEVELOPMENT
- Hypoxia-inducible Factor 1 (HIF-1) Promotes Extracellular Matrix Remodeling under Hypoxic Conditions by InducingP4HA1, P4HA2,andPLOD2Expression in Fibroblasts
- (2013) Daniele M. Gilkes et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Epigenetic changes in the progression of Alzheimer's disease
- (2013) M.A. Bradley-Whitman et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Suppression of eIF2α kinases alleviates Alzheimer's disease–related plasticity and memory deficits
- (2013) Tao Ma et al. NATURE NEUROSCIENCE
- Disruption of neocortical histone H3 homeostasis by soluble Aβ: implications for Alzheimer's disease
- (2013) Christina Unger Lithner et al. NEUROBIOLOGY OF AGING
- Blood pressure decrease correlates with tau pathology and memory decline in hypertensive elderly
- (2013) Lidia Glodzik et al. NEUROBIOLOGY OF AGING
- ALKBH1 Is Dispensable for Abasic Site Cleavage during Base Excision Repair and Class Switch Recombination
- (2013) Tina A. Müller et al. PLoS One
- JMJD5 regulates PKM2 nuclear translocation and reprograms HIF-1 -mediated glucose metabolism
- (2013) H.-J. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Deletion of mouse Alkbh7 leads to obesity
- (2013) A. Solberg et al. Journal of Molecular Cell Biology
- ALKBH4-dependent demethylation of actin regulates actomyosin dynamics
- (2013) Ming-Ming Li et al. Nature Communications
- Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
- (2012) Scott J. Dixon et al. CELL
- Neural Stem Cells and Neurogenesis in the Adult
- (2012) Christian Göritz et al. Cell Stem Cell
- JMJD5, a Jumonji C (JmjC) Domain-containing Protein, Negatively Regulates Osteoclastogenesis by Facilitating NFATc1 Protein Degradation
- (2012) Min-Young Youn et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Histone Lysine Methylation Dynamics: Establishment, Regulation, and Biological Impact
- (2012) Joshua C. Black et al. MOLECULAR CELL
- ALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility
- (2012) Guanqun Zheng et al. MOLECULAR CELL
- Oxygenase-catalyzed ribosome hydroxylation occurs in prokaryotes and humans
- (2012) Wei Ge et al. Nature Chemical Biology
- TAp63γ Demethylation Regulates Protein Stability and Cellular Distribution during Neural Stem Cell Differentiation
- (2012) Maria B. Fonseca et al. PLoS One
- Tau proteins in serum predict neurological outcome after hypoxic brain injury from cardiac arrest: Results of a pilot study
- (2012) Jeffrey Randall et al. RESUSCITATION
- Crystal structure of PHYHD1A, a 2OG oxygenase related to phytanoyl-CoA hydroxylase
- (2011) Zhihong Zhang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Lung cancer-associated JmjC domain protein mdig suppresses formation of tri-methyl lysine 9 of histone H3
- (2011) Yongju Lu et al. CELL CYCLE
- Genome-wide and gene-based association implicates FRMD6 in alzheimer disease
- (2011) Mun-Gwan Hong et al. HUMAN MUTATION
- Interactions of Pathological Hallmark Proteins
- (2011) Judit Oláh et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Crystal Structure and RNA Binding Properties of the RNA Recognition Motif (RRM) and AlkB Domains in Human AlkB Homolog 8 (ABH8), an Enzyme Catalyzing tRNA Hypermodification
- (2011) Chiara Pastore et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Lysine-specific Demethylase 2B (KDM2B)-let-7-Enhancer of Zester Homolog 2 (EZH2) Pathway Regulates Cell Cycle Progression and Senescence in Primary Cells
- (2011) Alexandros Tzatsos et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The hydroxylation activity of Jmjd6 is required for its homo-oligomerization
- (2011) Gang Han et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Histone Methylation by PRC2 Is Inhibited by Active Chromatin Marks
- (2011) Frank W. Schmitges et al. MOLECULAR CELL
- N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO
- (2011) Guifang Jia et al. Nature Chemical Biology
- Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders
- (2011) Berislav V. Zlokovic NATURE REVIEWS NEUROSCIENCE
- Toward an integrated genetic and epigenetic approach to Alzheimer's disease
- (2011) Jonathan Mill NEUROBIOLOGY OF AGING
- Insulin-induced neurite-like process outgrowth: Acceleration of tau protein synthesis via a phosphoinositide 3-kinase∼mammalian target of rapamycin pathway
- (2011) Takayuki Nemoto et al. NEUROCHEMISTRY INTERNATIONAL
- Aspartyl-(asparaginyl) β-Hydroxylase, Hypoxia-Inducible Factor-1α and Notch Cross-Talk in Regulating Neuronal Motility
- (2011) Margot Lawton et al. Oxidative Medicine and Cellular Longevity
- Human AlkB Homologue 5 Is a Nuclear 2-Oxoglutarate Dependent Oxygenase and a Direct Target of Hypoxia-Inducible Factor 1α (HIF-1α)
- (2011) Armin Thalhammer et al. PLoS One
- ALKBH8-mediated formation of a novel diastereomeric pair of wobble nucleosides in mammalian tRNA
- (2011) Erwin van den Born et al. Nature Communications
- Why Do We Need Multifunctional Neuroprotective and Neurorestorative Drugs for Parkinson's and Alzheimer's Diseases as Disease Modifying Agents
- (2011) Moussa B. H. Youdim Experimental Neurobiology
- The AlkB Domain of Mammalian ABH8 Catalyzes Hydroxylation of 5-Methoxycarbonylmethyluridine at the Wobble Position of tRNA
- (2010) Ye Fu et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Increased activity of Th-17 and Th-9 lymphocytes and a skewing of the post-thymic differentiation pathway are seen in Alzheimer’s disease
- (2010) Marina Saresella et al. BRAIN BEHAVIOR AND IMMUNITY
- The X-linked mental retardation gene PHF8 is a histone demethylase involved in neuronal differentiation
- (2010) Jihui Qiu et al. CELL RESEARCH
- The amyloid precursor protein intracellular domain alters gene expression and induces neuron-specific apoptosis
- (2010) Takeshi Ohkawara et al. GENE
- Expanding Role of the Jumonji C Domain as an RNA Hydroxylase
- (2010) Akiko Noma et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Crystal Structure of the 2-Oxoglutarate- and Fe(II)-Dependent Lysyl Hydroxylase JMJD6
- (2010) Monica Mantri et al. JOURNAL OF MOLECULAR BIOLOGY
- Analysis of Jmjd6 Cellular Localization and Testing for Its Involvement in Histone Demethylation
- (2010) Phillip Hahn et al. PLoS One
- Jumonji domain protein JMJD5 functions in both the plant and human circadian systems
- (2010) M. A. Jones et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- KDM8, a H3K36me2 histone demethylase that acts in the cyclin A1 coding region to regulate cancer cell proliferation
- (2010) D. A. Hsia et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Epigenetic regulation in the pathophysiology of Alzheimer's disease
- (2010) Leonidas Chouliaras et al. PROGRESS IN NEUROBIOLOGY
- HIF Prolyl Hydroxylase Inhibitors Prevent Neuronal Death Induced by Mitochondrial Toxins: Therapeutic Implications for Huntington's Disease and Alzheimer's Disease
- (2009) Zoya Niatsetskaya et al. ANTIOXIDANTS & REDOX SIGNALING
- Regulation of the osteoblast-specific transcription factor Osterix by NO66, a Jumonji family histone demethylase
- (2009) Krishna M Sinha et al. EMBO JOURNAL
- Mint3 Enhances the Activity of Hypoxia-inducible Factor-1 (HIF-1) in Macrophages by Suppressing the Activity of Factor Inhibiting HIF-1
- (2009) Takeharu Sakamoto et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2009) John R Horton et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Selective targeting of perivascular macrophages for clearance of -amyloid in cerebral amyloid angiopathy
- (2009) C. A. Hawkes et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Alzheimer's disease-like pathological features in transgenic mice expressing the APP intracellular domain
- (2009) K. Ghosal et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Connective Tissue Disorder Caused by Mutations of the Lysyl Hydroxylase 3 Gene
- (2008) Antti M. Salo et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Antioxidants, HIF Prolyl Hydroxylase Inhibitors or Short Interfering RNAs to BNIP3 or PUMA, Can Prevent Prodeath Effects of the Transcriptional Activator, HIF-1α, in a Mouse Hippocampal Neuronal Line
- (2008) Leila R. Aminova et al. ANTIOXIDANTS & REDOX SIGNALING
- Regulation of Jumonji-domain-containing histone demethylases by hypoxia-inducible factor (HIF)-1α
- (2008) Patrick J. Pollard et al. BIOCHEMICAL JOURNAL
- Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO
- (2008) Guifang Jia et al. FEBS LETTERS
- Human AlkB Homolog 1 Is a Mitochondrial Protein That Demethylates 3-Methylcytosine in DNA and RNA
- (2008) Marianne Pedersen Westbye et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Characterization of Recombinant Human Prolyl 3-Hydroxylase Isoenzyme 2, an Enzyme Modifying the Basement Membrane Collagen IV
- (2008) Päivi Tiainen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Blocking TGF-β–Smad2/3 innate immune signaling mitigates Alzheimer-like pathology
- (2008) Terrence Town et al. NATURE MEDICINE
- The role of oxygen availability in embryonic development and stem cell function
- (2008) M. Celeste Simon et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Phosphorylation of the Translation Initiation Factor eIF2α Increases BACE1 Levels and Promotes Amyloidogenesis
- (2008) Tracy O'Connor et al. NEURON
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