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Title
The roles of Jumonji-type oxygenases in human disease
Authors
Keywords
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Journal
Epigenomics
Volume 6, Issue 1, Pages 89-120
Publisher
Future Medicine Ltd
Online
2014-02-28
DOI
10.2217/epi.13.79
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- KDM8, a H3K36me2 histone demethylase that acts in the cyclin A1 coding region to regulate cancer cell proliferation
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- Long Noncoding RNA as Modular Scaffold of Histone Modification Complexes
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- Histone demethylases in development and disease
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- Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies
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- Epigenetic regulation of the alternatively activated macrophage phenotype
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- A Novel Human AlkB Homologue, ALKBH8, Contributes to Human Bladder Cancer Progression
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- Autism-associated familial microdeletion of Xp11.22
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- Human AlkB homologue 1 (ABH1) exhibits DNA lyase activity at abasic sites
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- Regulation of the osteoblast-specific transcription factor Osterix by NO66, a Jumonji family histone demethylase
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- Jmjd3 contributes to the control of gene expression in LPS-activated macrophages
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- Epigenetic reprogramming during wound healing: loss of polycomb-mediated silencing may enable upregulation of repair genes
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- Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RAS
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- The H3K27me3 demethylase JMJD3 contributes to the activation of the INK4A-ARF locus in response to oncogene- and stress-induced senescence
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- Obesity and metabolic syndrome in histone demethylase JHDM2a-deficient mice
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- Genome-wide mapping of SMAD target genes reveals the role of BMP signaling in embryonic stem cell fate determination
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- Jmjd1a Demethylase-regulated Histone Modification Is Essential for cAMP-response Element Modulator-regulated Gene Expression and Spermatogenesis
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- Nickel Ions Inhibit Histone Demethylase JMJD1A and DNA Repair Enzyme ABH2 by Replacing the Ferrous Iron in the Catalytic Centers
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- A Novel Mammalian Flavin-dependent Histone Demethylase
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- Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins
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- Expression of Mina53, a novel c-Myc target gene, is a favorable prognostic marker in early stage lung cancer
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- KDM1B is a histone H3K4 demethylase required to establish maternal genomic imprints
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- Role of Jhdm2a in regulating metabolic gene expression and obesity resistance
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- Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer
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- Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases
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- Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1
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- Gene expression analysis on anterior temporal neocortex of patients with intractable epilepsy
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- A novel mutation inJARID1C/SMCX in a patient with autism spectrum disorder (ASD)
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- Dynamic protein methylation in chromatin biology
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- Genetic Variants of FTO Influence Adiposity, Insulin Sensitivity, Leptin Levels, and Resting Metabolic Rate in the Quebec Family Study
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- Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO
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- dKDM2 couples histone H2A ubiquitylation to histone H3 demethylation during Polycomb group silencing
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- Spermatogenesis-specific association of SMCY and MSH5
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- Novel genetic variant in FTO influences insulin levels and insulin resistance in severely obese children and adolescents
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- Human AlkB Homolog 1 Is a Mitochondrial Protein That Demethylates 3-Methylcytosine in DNA and RNA
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- Comprehensive Analysis of DNA Repair Gene Variants and Risk of Meningioma
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- The Histone Demethylase KDM5b/JARID1b Plays a Role in Cell Fate Decisions by Blocking Terminal Differentiation
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- Alterations in candidate genes PHF2, FANCC, PTCH1 and XPA at chromosomal 9q22.3 region: Pathological significance in early- and late-onset breast carcinoma
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- The lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylation
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- The H3K36 demethylase Jhdm1b/Kdm2b regulates cell proliferation and senescence through p15Ink4b
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- Apoptotic signaling by c-MYC
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