Nuclear factor‐kappa β as a therapeutic target for Alzheimer's disease
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Title
Nuclear factor‐kappa β as a therapeutic target for Alzheimer's disease
Authors
Keywords
-
Journal
JOURNAL OF NEUROCHEMISTRY
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2019-02-26
DOI
10.1111/jnc.14687
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Note: Only part of the references are listed.- Melatonin ameliorates Aβ42 -induced alteration of βAPP-processing secretases via the melatonin receptor through the Pin1/GSK3β/NF-κB pathway in SH-SY5Y cells
- (2018) Vorapin Chinchalongporn et al. JOURNAL OF PINEAL RESEARCH
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- (2017) Asokan Prema et al. JOURNAL OF ALZHEIMERS DISEASE
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- (2017) Zhong-Hong Kong et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Berberine attenuates cognitive impairment and ameliorates tau hyperphosphorylation by limiting the self-perpetuating pathogenic cycle between NF-κB signaling, oxidative stress and neuroinflammation
- (2017) Wenbo He et al. Pharmacological Reports
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- (2017) Youngjin Park et al. Scientific Reports
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- (2017) Ilias Kounatidis et al. Cell Reports
- Acute Hypoxia Induced an Imbalanced M1/M2 Activation of Microglia through NF-κB Signaling in Alzheimer’s Disease Mice and Wild-Type Littermates
- (2017) Feng Zhang et al. Frontiers in Aging Neuroscience
- NF‐κB Signaling in Gastric Cancer
- (2017) Olga Sokolova et al. Toxins
- Nuclear Factor-Kappa B and Alzheimer Disease, Unifying Genetic and Environmental Risk Factors from Cell to Humans
- (2017) Simon Vann Jones et al. Frontiers in Immunology
- Why has therapy development for dementia failed in the last two decades?
- (2016) Serge Gauthier et al. Alzheimers & Dementia
- Bioactive effects of quercetin in the central nervous system: Focusing on the mechanisms of actions
- (2016) Natarajan Suganthy et al. BIOMEDICINE & PHARMACOTHERAPY
- Efficacy of omega-3 highly unsaturated fatty acids in the treatment of depression
- (2016) Brian Hallahan et al. BRITISH JOURNAL OF PSYCHIATRY
- Alcohol resistance inDrosophilais modulated by the Toll innate immune pathway
- (2016) B. R. Troutwine et al. GENES BRAIN AND BEHAVIOR
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- (2016) LiMei Qin et al. JOURNAL OF NEUROCHEMISTRY
- Rapamycin inhibits lipopolysaccharide-induced neuroinflammation in vitro and in vivo
- (2016) Na-Shun Mengke et al. Molecular Medicine Reports
- Regulation of SET Gene Expression by NFkB
- (2016) Yi Feng et al. MOLECULAR NEUROBIOLOGY
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- (2016) Shafiq Ur Rehman et al. MOLECULAR NEUROBIOLOGY
- The Curcumin Analog C-150, Influencing NF-κB, UPR and Akt/Notch Pathways Has Potent Anticancer Activity In Vitro and In Vivo
- (2016) László Hackler et al. PLoS One
- Amyloid-β peptide protects against microbial infection in mouse and worm models of Alzheimer’s disease
- (2016) Deepak Kumar Vijaya Kumar et al. Science Translational Medicine
- Reactive Oxygen Species, Redox Signaling and Neuroinflammation in Alzheimer's Disease: The NF-κB Connection
- (2015) Upinder Kaur et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Alzheimer-associated A oligomers impact the central nervous system to induce peripheral metabolic deregulation
- (2015) J. R. Clarke et al. EMBO Molecular Medicine
- Significance of NF-κB as a pivotal therapeutic target in the neurodegenerative pathologies of Alzheimer’s disease and multiple sclerosis
- (2015) Mythily Srinivasan et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- All-trans-retinoic Acid ReducesBACE1Expression under Inflammatory Conditions via Modulation of Nuclear Factor κB (NFκB) Signaling
- (2015) Ruishan Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The protein arginine methyltransferase PRMT5 regulates Aβ-induced toxicity in human cells andCaenorhabditis elegansmodels of Alzheimer's disease
- (2015) Xin Quan et al. JOURNAL OF NEUROCHEMISTRY
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- (2015) Yves Dondelinger et al. MOLECULAR CELL
- β-amyloid disrupts human NREM slow waves and related hippocampus-dependent memory consolidation
- (2015) Bryce A Mander et al. NATURE NEUROSCIENCE
- RIPK1 and RIPK3: critical regulators of inflammation and cell death
- (2015) Kim Newton TRENDS IN CELL BIOLOGY
- Metabolic learning and memory formation by the brain influence systemic metabolic homeostasis
- (2015) Yumin Zhang et al. Nature Communications
- Integrated genomic approaches identify major pathways and upstream regulators in late onset Alzheimer’s disease
- (2015) Xinzhong Li et al. Scientific Reports
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- (2015) David S. Black et al. JAMA Internal Medicine
- Plant polyphenols as inhibitors of NF-κB induced cytokine production—a potential anti-inflammatory treatment for Alzheimer's disease?
- (2015) Niloo Karunaweera et al. Frontiers in Molecular Neuroscience
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- (2015) Barbara Kaltschmidt et al. Frontiers in Molecular Neuroscience
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- (2015) Annamaria Lanzillotta et al. Frontiers in Neurology
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- (2015) Young-Mi Lim et al. PLoS One
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- (2014) Arumugam R. Jayakumar et al. JOURNAL OF NEUROTRAUMA
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- (2014) Xi-Chen Zhu et al. MOLECULAR NEUROBIOLOGY
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- (2012) P W Gold et al. MOLECULAR PSYCHIATRY
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- (2012) Vinod Tiwari et al. NEUROCHEMISTRY INTERNATIONAL
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- (2012) Stefka Mincheva-Tasheva et al. NEUROSCIENTIST
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- (2012) Koon-Ho Chan et al. PLoS One
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- (2012) A. J. Petersen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Circadian clock protein cryptochrome regulates the expression of proinflammatory cytokines
- (2012) R. Narasimamurthy et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2011) Rebecca G. Baker et al. Cell Metabolism
- Increased NF-κB signalling up-regulates BACE1 expression and its therapeutic potential in Alzheimer's disease
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- (2011) Dong Kug Choi et al. MOLECULES
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- (2011) Sudarshana Purkayastha et al. NATURE MEDICINE
- Induction of Innate Immune Gene Expression Cascades in Brain Slice Cultures by Ethanol: Key Role of NF-κB and Proinflammatory Cytokines
- (2010) Jian Zou et al. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH
- Non-canonical NF-κB signaling pathway
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- (2010) Michela Guglielmotto et al. NEUROBIOLOGY OF AGING
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- (2010) Jill Wentzell et al. NEUROBIOLOGY OF DISEASE
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- (2009) L. R. Squire JOURNAL OF NEUROSCIENCE
- Green Tea (-)-Epigallocatechin-3-Gallate Inhibits β-Amyloid-Induced Cognitive Dysfunction through Modification of Secretase Activity via Inhibition of ERK and NF-κB Pathways in Mice
- (2009) Jae Woong Lee et al. JOURNAL OF NUTRITION
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- (2009) Clifford R Jack et al. LANCET NEUROLOGY
- Targeting p38 MAPK pathway for the treatment of Alzheimer's disease
- (2009) Lenka Munoz et al. NEUROPHARMACOLOGY
- Apolipoprotein E-Mimetics Inhibit Neurodegeneration and Restore Cognitive Functions in a Transgenic Drosophila Model of Alzheimer's Disease
- (2009) Svetlana Sarantseva et al. PLoS One
- NF- B in the Nervous System
- (2009) B. Kaltschmidt et al. Cold Spring Harbor Perspectives in Biology
- The NF- B Family of Transcription Factors and Its Regulation
- (2009) A. Oeckinghaus et al. Cold Spring Harbor Perspectives in Biology
- Hypothalamic proinflammatory lipid accumulation, inflammation, and insulin resistance in rats fed a high-fat diet
- (2008) Kelly A. Posey et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Hypothalamic IKKβ/NF-κB and ER Stress Link Overnutrition to Energy Imbalance and Obesity
- (2008) Xiaoqing Zhang et al. CELL
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- (2008) Ellen Niederberger et al. FASEB JOURNAL
- The Toll→NFκB Signaling Pathway Mediates the Neuropathological Effects of the Human Alzheimer's Aβ42 Polypeptide in Drosophila
- (2008) Lihua Tan et al. PLoS One
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