The histone demethylase PHF8 regulates astrocyte differentiation and function

Identification of region-specific astrocyte subtypes at single cell resolution

(2020) Mykhailo Y. Batiuk et al.   Nature Communications

Region-Specific Transcriptional Control of Astrocyte Function Oversees Local Circuit Activities

(2020) Anna Yu-Szu Huang et al.   NEURON

Sulfatase 2 promotes generation of a spinal cord astrocyte subtype that stands out through the expression of Olig2

(2019) David Ohayon et al.   GLIA

PHF2 histone demethylase prevents DNA damage and genome instability by controlling cell cycle progression of neural progenitors

(2019) Stella Pappa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Do Astrocytes Play a Role in Intellectual Disabilities?

(2019) Noémie Cresto et al.   TRENDS IN NEUROSCIENCES

Lineage specific transcription factors and epigenetic regulators mediate TGFβ-dependent enhancer activation

(2018) Raquel Fueyo et al.   NUCLEIC ACIDS RESEARCH

Cell adhesion and matricellular support by astrocytes of the tripartite synapse

(2018) Anne E.J. Hillen et al.   PROGRESS IN NEUROBIOLOGY

Phf8 histone demethylase deficiency causes cognitive impairments through the mTOR pathway

(2018) Xuemei Chen et al.   Nature Communications

Olig2-Lineage Astrocytes: A Distinct Subtype of Astrocytes That Differs from GFAP Astrocytes

(2018) Kouko Tatsumi et al.   Frontiers in Neuroanatomy

Astrocyte-Secreted Glypican 4 Regulates Release of Neuronal Pentraxin 1 from Axons to Induce Functional Synapse Formation

(2017) Isabella Farhy-Tselnicker et al.   NEURON

The histone demethylase PHF8 is a molecular safeguard of the IFNγ response

(2017) Elena Asensio-Juan et al.   NUCLEIC ACIDS RESEARCH

Phf8 loss confers resistance to depression-like and anxiety-like behaviors in mice

(2017) Ryan M. Walsh et al.   Nature Communications

Astrocytes Assemble Thalamocortical Synapses by Bridging NRX1α and NL1 via Hevin

(2016) Sandeep K. Singh et al.   CELL

Purification and Characterization of Progenitor and Mature Human Astrocytes Reveals Transcriptional and Functional Differences with Mouse

(2016) Ye Zhang et al.   NEURON

Astrocyte-secreted thrombospondin-1 modulates synapse and spine defects in the fragile X mouse model

(2016) Connie Cheng et al.   Molecular Brain

ChIPseeker: an R/Bioconductor package for ChIP peak annotation, comparison and visualization

(2015) Guangchuang Yu et al.   BIOINFORMATICS

SnapShot: Astrocytes in Health and Disease

(2015) Shane Liddelow et al.   CELL

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

Regulation of CBP and Tip60 coordinates histone acetylation at local and global levels during Ras-induced transformation

(2014) Sara Sánchez-Molina et al.   CARCINOGENESIS

Characterization of Panglial Gap Junction Networks in the Thalamus, Neocortex, and Hippocampus Reveals a Unique Population of Glial Cells

(2014) Stephanie Griemsmann et al.   CEREBRAL CORTEX

An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

(2014) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

Gliotransmitters Travel in Time and Space

(2014) Alfonso Araque et al.   NEURON

Jaccard index based similarity measure to compare transcription factor binding site models

(2013) Ilya E Vorontsov et al.   Algorithms for Molecular Biology

NFIA Controls Telencephalic Progenitor Cell Differentiation through Repression of the Notch Effector Hes1

(2013) M. Piper et al.   JOURNAL OF NEUROSCIENCE

Emerging roles of astrocytes in neural circuit development

(2013) Laura E. Clarke et al.   NATURE REVIEWS NEUROSCIENCE

A Critical Role for Sox9 in Notch-Induced Astrogliogenesis and Stem Cell Maintenance

(2013) Simone Martini et al.   STEM CELLS

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Astrocytes conspire with neurons during progression of neurological disease

(2012) James C McGann et al.   CURRENT OPINION IN NEUROBIOLOGY

Genome-wide analysis reveals that Smad3 and JMJD3 HDM co-activate the neural developmental program

(2012) C. Estaras et al.   DEVELOPMENT

NOTCH1 Nuclear Interactome Reveals Key Regulators of Its Transcriptional Activity and Oncogenic Function

(2012) Ahmad Yatim et al.   MOLECULAR CELL

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

The histone demethylase PHF8 is essential for cytoskeleton dynamics

(2012) Elena Asensio-Juan et al.   NUCLEIC ACIDS RESEARCH

Plant homeodomain fingers form a helping hand for transcription

(2011) Klaus Fortschegger et al.   Epigenetics

Macroglial Plasticity and the Origins of Reactive Astroglia in Experimental Autoimmune Encephalomyelitis

(2011) F. Guo et al.   JOURNAL OF NEUROSCIENCE

Control of excitatory CNS synaptogenesis by astrocyte-secreted proteins Hevin and SPARC

(2011) Hakan Kucukdereli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The X-linked mental retardation gene PHF8 is a histone demethylase involved in neuronal differentiation

(2010) Jihui Qiu et al.   CELL RESEARCH

Origin of New Glial Cells in Intact and Injured Adult Spinal Cord

(2010) Fanie Barnabé-Heider et al.   Cell Stem Cell

KDM7 is a dual demethylase for histone H3 Lys 9 and Lys 27 and functions in brain development

(2010) Y.-i. Tsukada et al.   GENES & DEVELOPMENT

Recognition of Histone H3K4 Trimethylation by the Plant Homeodomain of PHF2 Modulates Histone Demethylation

(2010) Hong Wen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PHF8 Targets Histone Methylation and RNA Polymerase II To Activate Transcription

(2010) K. Fortschegger et al.   MOLECULAR AND CELLULAR BIOLOGY

A Functional Link between the Histone Demethylase PHF8 and the Transcription Factor ZNF711 in X-Linked Mental Retardation

(2010) Daniela Kleine-Kohlbrecher et al.   MOLECULAR CELL

PHF8 mediates histone H4 lysine 20 demethylation events involved in cell cycle progression

(2010) Wen Liu et al.   NATURE

Histone H4K20/H3K9 demethylase PHF8 regulates zebrafish brain and craniofacial development

(2010) Hank H. Qi et al.   NATURE

Autism-associated familial microdeletion of Xp11.22

(2009) Y Qiao et al.   CLINICAL GENETICS

Committed Neuronal Precursors Confer Astrocytic Potential on Residual Neural Precursor Cells

(2009) Masakazu Namihira et al.   DEVELOPMENTAL CELL

PHF8, a gene associated with cleft lip/palate and mental retardation, encodes for an Nε-dimethyl lysine demethylase

(2009) Christoph Loenarz et al.   HUMAN MOLECULAR GENETICS

Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases

(2009) John R Horton et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Genetic and epigenetic defects in mental retardation

(2008) Jamie M. Kramer et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Autoacetylation Regulates P/CAF Nuclear Localization

(2008) Noemí Blanco-García et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Model-based Analysis of ChIP-Seq (MACS)

(2008) Yong Zhang et al.   GENOME BIOLOGY