Early miR-155 upregulation contributes to neuroinflammation in Alzheimer's disease triple transgenic mouse model

Identification of miRNA Changes in Alzheimer's Disease Brain and CSF Yields Putative Biomarkers and Insights into Disease Pathways

(2017) John P. Cogswell et al.   JOURNAL OF ALZHEIMERS DISEASE

S100P/RAGE signaling regulates microRNA-155 expression via AP-1 activation in colon cancer

(2013) Benjamin Chidi Onyeagucha et al.   EXPERIMENTAL CELL RESEARCH

Operational dissection of β-amyloid cytopathic effects on cultured neurons

(2013) Noelle Callizot et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Functional Impairment of Microglia Coincides with Beta-Amyloid Deposition in Mice with Alzheimer-Like Pathology

(2013) Grietje Krabbe et al.   PLoS One

Tumor-targeted Chlorotoxin-coupled Nanoparticles for Nucleic Acid Delivery to Glioblastoma Cells: A Promising System for Glioblastoma Treatment

(2013) Pedro M Costa et al.   Molecular Therapy-Nucleic Acids

The Classification of Microglial Activation Phenotypes on Neurodegeneration and Regeneration in Alzheimer’s Disease Brain

(2012) Megan M. Varnum et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Calpastatin-mediated inhibition of calpains in the mouse brain prevents mutant ataxin 3 proteolysis, nuclear localization and aggregation, relieving Machado-Joseph disease

(2012) A. T. Simoes et al.   BRAIN

MicroRNAs are universal regulators of differentiation, activation, and polarization of microglia and macrophages in normal and diseased CNS

(2012) Eugene D. Ponomarev et al.   GLIA

A pathway-based analysis provides additional support for an immune-related genetic susceptibility to Parkinson's disease

(2012) Peter Holmans et al.   HUMAN MOLECULAR GENETICS

Enhanced Expression of Glia Maturation Factor Correlates with Glial Activation in the Brain of Triple Transgenic Alzheimer’s Disease Mice

(2012) Smita Zaheer et al.   NEUROCHEMICAL RESEARCH

TREM2 Variants in Alzheimer's Disease

(2012) Rita Guerreiro et al.   NEW ENGLAND JOURNAL OF MEDICINE

MicroRNA-155 Modulates Treg and Th17 Cells Differentiation and Th17 Cell Function by Targeting SOCS1

(2012) Rui Yao et al.   PLoS One

The diagnosis of mild cognitive impairment due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Marilyn S. Albert et al.   Alzheimers & Dementia

Interferon regulatory factor 3 inhibits astrocyte inflammatory gene expression through suppression of the proinflammatory miR-155 and miR-155*

(2011) Leonid Tarassishin et al.   GLIA

miR-155 modulates microglia-mediated immune response by down-regulating SOCS-1 and promoting cytokine and nitric oxide production

(2011) Ana L. Cardoso et al.   IMMUNOLOGY

Inflammation in the early stages of neurodegenerative pathology

(2011) Preeti J. Khandelwal et al.   JOURNAL OF NEUROIMMUNOLOGY

Differential expression of miRNA-146a-regulated inflammatory genes in human primary neural, astroglial and microglial cells

(2011) Yuan Yuan Li et al.   NEUROSCIENCE LETTERS

Species-specific microRNA roles elucidated following astrocyte activation

(2011) Eyal Mor et al.   NUCLEIC ACIDS RESEARCH

MicroRNAs in NF- B signaling

(2011) X. Ma et al.   Journal of Molecular Cell Biology

Mechanisms Underlying Inflammation in Neurodegeneration

(2010) Christopher K. Glass et al.   CELL

Astrocyte TLR4 activation induces a proinflammatory environment through the interplay between MyD88-dependent NFκB signaling, MAPK, and Jak1/Stat1 pathways

(2010) Roser Gorina et al.   GLIA

β-Amyloid1–42Gene Transfer Model Exhibits Intraneuronal Amyloid, Gliosis, Tau Phosphorylation, and Neuronal Loss

(2010) G. William Rebeck et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Micro RNA-125b (miRNA-125b) function in astrogliosis and glial cell proliferation

(2010) A.I. Pogue et al.   NEUROSCIENCE LETTERS

Genetic Evidence Implicates the Immune System and Cholesterol Metabolism in the Aetiology of Alzheimer's Disease

(2010) Lesley Jones et al.   PLoS One

A Nurr1/CoREST Pathway in Microglia and Astrocytes Protects Dopaminergic Neurons from Inflammation-Induced Death

(2009) Kaoru Saijo et al.   CELL

Tf-lipoplex-mediated c-Jun silencing improves neuronal survival following excitotoxic damage in vivo

(2009) A.L.C. Cardoso et al.   JOURNAL OF CONTROLLED RELEASE

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

(2009) Cameron R Stewart et al.   NATURE IMMUNOLOGY

Expression of inflammatory genes induced by beta-amyloid peptides in human brain endothelial cells and in Alzheimer's brain is mediated by the JNK-AP1 signaling pathway

(2009) Vanja Vukic et al.   NEUROBIOLOGY OF DISEASE

Immune Activation in Brain Aging and Neurodegeneration: Too Much or Too Little?

(2009) Kurt M. Lucin et al.   NEURON

Silencing of microRNA-155 in mice during acute inflammatory response leads to derepression of c/ebp Beta and down-regulation of G-CSF

(2009) Jesper Worm et al.   NUCLEIC ACIDS RESEARCH

Imaging individual microRNAs in single mammalian cells in situ

(2009) J. Lu et al.   NUCLEIC ACIDS RESEARCH

SOCS1 and SOCS3 in the control of CNS immunity

(2009) Brandi J. Baker et al.   TRENDS IN IMMUNOLOGY

Alterations of the microRNA network cause neurodegenerative disease

(2009) Sébastien S. Hébert et al.   TRENDS IN NEUROSCIENCES

Chronic Neuron-Specific Tumor Necrosis Factor-Alpha Expression Enhances the Local Inflammatory Environment Ultimately Leading to Neuronal Death in 3xTg-AD Mice

(2008) Michelle C. Janelsins et al.   AMERICAN JOURNAL OF PATHOLOGY

Toll-like receptor-4 mediates neuronal apoptosis induced by amyloid β-peptide and the membrane lipid peroxidation product 4-hydroxynonenal

(2008) Sung-Chun Tang et al.   EXPERIMENTAL NEUROLOGY

An NF-κB-sensitive Micro RNA-146a-mediated Inflammatory Circuit in Alzheimer Disease and in Stressed Human Brain Cells

(2008) Walter J. Lukiw et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neurotoxic effect of oligomeric and fibrillar species of amyloid-beta peptide 1-42: Involvement of endoplasmic reticulum calcium release in oligomer-induced cell death

(2008) R. Resende et al.   NEUROSCIENCE

Epstein–Barr virus latent membrane protein 1 trans-activates miR-155 transcription through the NF-κB pathway

(2008) Graziana Gatto et al.   NUCLEIC ACIDS RESEARCH

Mechanisms of microglia accumulation in Alzheimer’s disease: therapeutic implications

(2008) Joseph El Khoury et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Screening of innate immune receptors in neurodegenerative diseases: A similar pattern

(2007) Maryse Letiembre et al.   NEUROBIOLOGY OF AGING