Cell–3D matrix interactions: recent advances and opportunities

Precise Tuning and Characterization of Viscoelastic Interfaces for the Study of Early Epithelial–Mesenchymal Transition Behaviors

(2022) Alice Chinghsuan Chang et al.   LANGMUIR

Myofibroblast YAP/TAZ activation is a key step in organ fibrogenesis

(2022) Xiaolin He et al.   JCI Insight

Improving preclinical studies through replications

(2021) Natascha Ingrid Drude et al.   eLife

Progressive pulmonary fibrosis is caused by elevated mechanical tension on alveolar stem cells

(2021) Huijuan Wu et al.   CELL

Local accumulation of extracellular matrix regulates global morphogenetic patterning in the developing mammary gland

(2021) Bryan A. Nerger et al.   CURRENT BIOLOGY

3D mesenchymal cell migration is driven by anterior cellular contraction that generates an extracellular matrix prestrain

(2021) Andrew D. Doyle et al.   DEVELOPMENTAL CELL

A Guide to the Composition and Functions of the Extracellular Matrix

(2021) Nikos K. Karamanos et al.   FEBS Journal

Myosin II and Arp2/3 crosstalk governs intracellular hydraulic pressure and lamellipodia formation

(2021) Shivani Patel et al.   MOLECULAR BIOLOGY OF THE CELL

Fueling Cell Invasion through Extracellular Matrix

(2021) Aastha Garde et al.   TRENDS IN CELL BIOLOGY

Mechanoresponsive metabolism in cancer cell migration and metastasis

(2021) Matthew R. Zanotelli et al.   Cell Metabolism

Enhanced substrate stress relaxation promotes filopodia-mediated cell migration

(2021) Kolade Adebowale et al.   NATURE MATERIALS

Preventing Engrailed-1 activation in fibroblasts yields wound regeneration without scarring

(2021) Shamik Mascharak et al.   SCIENCE

Extracellular Matrix Alignment Directs Provisional Matrix Assembly and Three Dimensional Fibrous Tissue Closure

(2021) Shoshana L. Das et al.   TISSUE ENGINEERING PART A

Recursive feedback between matrix dissipation and chemo-mechanical signaling drives oscillatory growth of cancer cell invadopodia

(2021) Ze Gong et al.   Cell Reports

Mechanosensitive Regulation of Fibrosis

(2021) Shuying Yang et al.   Cells

Viscoelasticity and Adhesion Signaling in Biomaterials Control Human Pluripotent Stem Cell Morphogenesis in 3D Culture

(2021) Dhiraj Indana et al.   ADVANCED MATERIALS

Engineering a 3D collective cancer invasion model with control over collagen fiber alignment

(2021) Chia-Yi Su et al.   BIOMATERIALS

Budding epithelial morphogenesis driven by cell-matrix versus cell-cell adhesion

(2021) Shaohe Wang et al.   CELL

Mechano-induced cell metabolism promotes microtubule glutamylation to force metastasis

(2021) Stéphanie Torrino et al.   Cell Metabolism

The Combined Influence of Viscoelastic and Adhesive Cues on Fibroblast Spreading and Focal Adhesion Organization

(2021) Erica Hui et al.   Cellular and Molecular Bioengineering

Yap Promotes Noncanonical Wnt Signals from Cardiomyocytes for Heart Regeneration

(2021) Shijie Liu et al.   CIRCULATION RESEARCH

Tissue mechanics in stem cell fate, development, and cancer

(2021) Mary-Kate Hayward et al.   DEVELOPMENTAL CELL

Engineering hydrogels with homogeneous mechanical properties for controlling stem cell lineage specification

(2021) Bin Xue et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enhanced mechanosensing of cells in synthetic 3D matrix with controlled biophysical dynamics

(2021) Boguang Yang et al.   Nature Communications

ADF and cofilin-1 collaborate to promote cortical actin flow and the leader bleb-based migration of confined cells

(2021) Maria F Ullo et al.   eLife

From Microspikes to Stress Fibers: Actin Remodeling in Breast Acini Drives Myosin II-Mediated Basement Membrane Invasion

(2021) Julian Eschenbruch et al.   Cells

Non-muscle myosin II isoforms orchestrate substrate stiffness sensing to promote cancer cell contractility and migration

(2021) Yueting Peng et al.   CANCER LETTERS

Aligned forces: Origins and mechanisms of cancer dissemination guided by extracellular matrix architecture

(2021) Arja Ray et al.   CURRENT OPINION IN CELL BIOLOGY

The extracellular matrix viscoelasticity as a regulator of cell and tissue dynamics

(2021) Alberto Elosegui-Artola   CURRENT OPINION IN CELL BIOLOGY

Adaptations in Hippo-Yap signaling and myofibroblast fate underlie scar-free ear appendage wound healing in spiny mice

(2021) Chris M. Brewer et al.   DEVELOPMENTAL CELL

Cell–extracellular matrix dynamics

(2021) Andrew D Doyle et al.   PHYSICAL BIOLOGY

Mechanical communication in fibrosis progression

(2021) Yi Long et al.   TRENDS IN CELL BIOLOGY

Bioengineered 3D models of human pancreatic cancer recapitulate in vivo tumour biology

(2021) David Osuna de la Peña et al.   Nature Communications

Collagen polarization promotes epithelial elongation by stimulating locoregional cell proliferation

(2021) Hiroko Katsuno-Kambe et al.   eLife

Phenotypic drug screening in a human fibrosis model identified a novel class of antifibrotic therapeutics

(2021) Michael Gerckens et al.   Science Advances

Force-dependent extracellular matrix remodeling by early-stage cancer cells alters diffusion and induces carcinoma-associated fibroblasts

(2020) Wei-Hung Jung et al.   BIOMATERIALS

Basement Membrane Regulates Fibronectin Organization Using Sliding Focal Adhesions Driven by a Contractile Winch

(2020) Jiaoyang Lu et al.   DEVELOPMENTAL CELL

Of Cell Shapes and Motion: The Physical Basis of Animal Cell Migration

(2020) Dani L. Bodor et al.   DEVELOPMENTAL CELL

Cellular locomotion using environmental topography

(2020) Anne Reversat et al.   NATURE

Cell response to substrate rigidity is regulated by active and passive cytoskeletal stress

(2020) Bryant L. Doss et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Collagen microarchitecture mechanically controls myofibroblast differentiation

(2020) Bo Ri Seo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pan-Cancer Analysis of the Genomic Alterations and Mutations of the Matrisome

(2020) Valerio Izzi et al.   Cancers

Mechanical feed-forward loops contribute to Idiopathic Pulmonary Fibrosis

(2020) Margaret A.T. Freeberg et al.   AMERICAN JOURNAL OF PATHOLOGY

Crosstalk between Cell Adhesion Complexes in Regulation of Mechanotransduction

(2020) Alba Zuidema et al.   BIOESSAYS

Stiff stroma increases breast cancer risk by inducing the oncogene ZNF217

(2020) Jason J. Northey et al.   JOURNAL OF CLINICAL INVESTIGATION

Effects of extracellular matrix viscoelasticity on cellular behaviour

(2020) Ovijit Chaudhuri et al.   NATURE

Cell–cell adhesion and 3D matrix confinement determine jamming transitions in breast cancer invasion

(2020) Olga Ilina et al.   NATURE CELL BIOLOGY

Durotaxis: The Hard Path from In Vitro to In Vivo

(2020) Adam Shellard et al.   DEVELOPMENTAL CELL

The mechanobiome: a goldmine for cancer therapeutics

(2020) Eleana Parajón et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The cell pushes back: The Arp2/3 complex is a key orchestrator of cellular responses to environmental forces

(2020) Vassilis Papalazarou et al.   CURRENT OPINION IN CELL BIOLOGY

Durotaxis by Human Cancer Cells

(2019) Brian J. DuChez et al.   BIOPHYSICAL JOURNAL

Adaptive F-Actin Polymerization and Localized ATP Production Drive Basement Membrane Invasion in the Absence of MMPs

(2019) Laura C. Kelley et al.   DEVELOPMENTAL CELL

The Driving Force: Nuclear Mechanotransduction in Cellular Function, Fate, and Disease

(2019) Melanie Maurer et al.   Annual Review of Biomedical Engineering

Nuclear positioning facilitates amoeboid migration along the path of least resistance

(2019) Jörg Renkawitz et al.   NATURE

Beyond proteases: Basement membrane mechanics and cancer invasion

(2019) Julie Chang et al.   JOURNAL OF CELL BIOLOGY

Myosin IIA suppresses glioblastoma development in a mechanically sensitive manner

(2019) Hannah S. Picariello et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of nuclear architecture, mechanics, and nucleocytoplasmic shuttling of epigenetic factors by cell geometric constraints

(2019) Farid Alisafaei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamic fibroblast contractions attract remote macrophages in fibrillar collagen matrix

(2019) Pardis Pakshir et al.   Nature Communications

Cell sensing and decision-making in confinement: The role of TRPM7 in a tug of war between hydraulic pressure and cross-sectional area

(2019) Runchen Zhao et al.   Science Advances

Persistent and polarized global actin flow is essential for directionality during cell migration

(2019) Lawrence Yolland et al.   NATURE CELL BIOLOGY

Mechanisms of 3D cell migration

(2019) Kenneth M. Yamada et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Selective YAP/TAZ inhibition in fibroblasts via dopamine receptor D1 agonism reverses fibrosis

(2019) Andrew J. Haak et al.   Science Translational Medicine

Matching material and cellular timescales maximizes cell spreading on viscoelastic substrates

(2018) Ze Gong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell contraction induces long-ranged stress stiffening in the extracellular matrix

(2018) Yu Long Han et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cellular Durotaxis Revisited: Initial-Position-Dependent Determination of the Threshold Stiffness Gradient to Induce Durotaxis

(2018) Kousuke Moriyama et al.   LANGMUIR

Targeted matrisome analysis identifies thrombospondin-2 and tenascin-C in aligned collagen stroma from invasive breast carcinoma

(2018) Lucas A. Tomko et al.   Scientific Reports

Matrix mechanical plasticity regulates cancer cell migration through confining microenvironments

(2018) Katrina M. Wisdom et al.   Nature Communications

Mechanoreciprocity in cell migration

(2017) Sjoerd van Helvert et al.   NATURE CELL BIOLOGY

Activating the nuclear piston mechanism of 3D migration in tumor cells

(2016) Ryan J. Petrie et al.   JOURNAL OF CELL BIOLOGY

Fibrous nonlinear elasticity enables positive mechanical feedback between cells and ECMs

(2016) Matthew S. Hall et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Local 3D matrix microenvironment regulates cell migration through spatiotemporal dynamics of contractility-dependent adhesions

(2015) Andrew D. Doyle et al.   Nature Communications

Force Fluctuations within Focal Adhesions Mediate ECM-Rigidity Sensing to Guide Directed Cell Migration

(2012) Sergey V. Plotnikov et al.   CELL

Aligned Collagen Is a Prognostic Signature for Survival in Human Breast Carcinoma

(2011) Matthew W. Conklin et al.   AMERICAN JOURNAL OF PATHOLOGY